Compile Data Set for Download or QSAR

Found 122 hits Enz. Inhib. hit(s) with all data for entry = 50043304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439017 (CHEMBL2420827) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(Nc2ccncn2)c1 Show InChI InChI=1S/C16H11Cl2N5O/c17-11-2-1-3-12(18)15(11)16(24)22-10-4-7-20-14(8-10)23-13-5-6-19-9-21-13/h1-9H,(H2,19,20,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50434821 (CHEMBL2387224) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C16H13Cl2N3O2/c17-11-2-1-3-12(18)14(11)16(23)20-10-6-7-19-13(8-10)21-15(22)9-4-5-9/h1-3,6-9H,4-5H2,(H2,19,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439014 (CHEMBL2420829) Show SMILES CCn1cc(Nc2cc(NC(=O)c3c(Cl)cccc3Cl)ccn2)cn1 Show InChI InChI=1S/C17H15Cl2N5O/c1-2-24-10-12(9-21-24)22-15-8-11(6-7-20-15)23-17(25)16-13(18)4-3-5-14(16)19/h3-10H,2H2,1H3,(H2,20,22,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439011 (CHEMBL2420826) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(Nc2cnccn2)c1 Show InChI InChI=1S/C16H11Cl2N5O/c17-11-2-1-3-12(18)15(11)16(24)22-10-4-5-20-13(8-10)23-14-9-19-6-7-21-14/h1-9H,(H2,20,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439018 (CHEMBL2420831) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1cc[nH]c(=O)c1 Show InChI InChI=1S/C12H8Cl2N2O2/c13-8-2-1-3-9(14)11(8)12(18)16-7-4-5-15-10(17)6-7/h1-6H,(H2,15,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439006 (CHEMBL2420828) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(Nc2cccnn2)c1 Show InChI InChI=1S/C16H11Cl2N5O/c17-11-3-1-4-12(18)15(11)16(24)21-10-6-8-19-14(9-10)22-13-5-2-7-20-23-13/h1-9H,(H2,19,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439012 (CHEMBL2420812) Show SMILES CCNC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C15H14Cl2N4O2/c1-2-18-15(23)21-12-8-9(6-7-19-12)20-14(22)13-10(16)4-3-5-11(13)17/h3-8H,2H2,1H3,(H3,18,19,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50434821 (CHEMBL2387224) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C16H13Cl2N3O2/c17-11-2-1-3-12(18)14(11)16(23)20-10-6-7-19-13(8-10)21-15(22)9-4-5-9/h1-3,6-9H,4-5H2,(H2,19,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439018 (CHEMBL2420831) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1cc[nH]c(=O)c1 Show InChI InChI=1S/C12H8Cl2N2O2/c13-8-2-1-3-9(14)11(8)12(18)16-7-4-5-15-10(17)6-7/h1-6H,(H2,15,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50434821 (CHEMBL2387224) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C16H13Cl2N3O2/c17-11-2-1-3-12(18)14(11)16(23)20-10-6-7-19-13(8-10)21-15(22)9-4-5-9/h1-3,6-9H,4-5H2,(H2,19,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of CDK9 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439007 (CHEMBL2420824) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(Nc2ccccn2)c1 Show InChI InChI=1S/C17H12Cl2N4O/c18-12-4-3-5-13(19)16(12)17(24)22-11-7-9-21-15(10-11)23-14-6-1-2-8-20-14/h1-10H,(H2,20,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439017 (CHEMBL2420827) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(Nc2ccncn2)c1 Show InChI InChI=1S/C16H11Cl2N5O/c17-11-2-1-3-12(18)15(11)16(24)22-10-4-7-20-14(8-10)23-13-5-6-19-9-21-13/h1-9H,(H2,19,20,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439005 (CHEMBL2420830) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc2[nH]ccc12 Show InChI InChI=1S/C14H9Cl2N3O/c15-9-2-1-3-10(16)12(9)14(20)19-11-5-7-18-13-8(11)4-6-17-13/h1-7H,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439016 (CHEMBL2420832) Show SMILES CCC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C15H13Cl2N3O2/c1-2-13(21)20-12-8-9(6-7-18-12)19-15(22)14-10(16)4-3-5-11(14)17/h3-8H,2H2,1H3,(H2,18,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50434821 (CHEMBL2387224) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C16H13Cl2N3O2/c17-11-2-1-3-12(18)14(11)16(23)20-10-6-7-19-13(8-10)21-15(22)9-4-5-9/h1-3,6-9H,4-5H2,(H2,19,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	253	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439015 (CHEMBL2420821) Show SMILES CC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C14H11Cl2N3O2/c1-8(20)18-12-7-9(5-6-17-12)19-14(21)13-10(15)3-2-4-11(13)16/h2-7H,1H3,(H2,17,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439014 (CHEMBL2420829) Show SMILES CCn1cc(Nc2cc(NC(=O)c3c(Cl)cccc3Cl)ccn2)cn1 Show InChI InChI=1S/C17H15Cl2N5O/c1-2-24-10-12(9-21-24)22-15-8-11(6-7-20-15)23-17(25)16-13(18)4-3-5-14(16)19/h3-10H,2H2,1H3,(H2,20,22,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439013 (CHEMBL2420835) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(NC(=O)CC2CC2)c1 Show InChI InChI=1S/C17H15Cl2N3O2/c18-12-2-1-3-13(19)16(12)17(24)21-11-6-7-20-14(9-11)22-15(23)8-10-4-5-10/h1-3,6-7,9-10H,4-5,8H2,(H2,20,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439012 (CHEMBL2420812) Show SMILES CCNC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C15H14Cl2N4O2/c1-2-18-15(23)21-12-8-9(6-7-19-12)20-14(22)13-10(16)4-3-5-11(13)17/h3-8H,2H2,1H3,(H3,18,19,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439011 (CHEMBL2420826) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(Nc2cnccn2)c1 Show InChI InChI=1S/C16H11Cl2N5O/c17-11-2-1-3-12(18)15(11)16(24)22-10-4-5-20-13(8-10)23-14-9-19-6-7-21-14/h1-9H,(H2,20,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439010 (CHEMBL2420836) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(NC(=O)C2CCC2)c1 Show InChI InChI=1S/C17H15Cl2N3O2/c18-12-5-2-6-13(19)15(12)17(24)21-11-7-8-20-14(9-11)22-16(23)10-3-1-4-10/h2,5-10H,1,3-4H2,(H2,20,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439009 (CHEMBL2420813) Show SMILES COC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C14H11Cl2N3O3/c1-22-14(21)19-11-7-8(5-6-17-11)18-13(20)12-9(15)3-2-4-10(12)16/h2-7H,1H3,(H2,17,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439008 (CHEMBL2420823) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(Nc2ccccc2)c1 Show InChI InChI=1S/C18H13Cl2N3O/c19-14-7-4-8-15(20)17(14)18(24)23-13-9-10-21-16(11-13)22-12-5-2-1-3-6-12/h1-11H,(H2,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439007 (CHEMBL2420824) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(Nc2ccccn2)c1 Show InChI InChI=1S/C17H12Cl2N4O/c18-12-4-3-5-13(19)16(12)17(24)22-11-7-9-21-15(10-11)23-14-6-1-2-8-20-14/h1-10H,(H2,20,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439006 (CHEMBL2420828) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(Nc2cccnn2)c1 Show InChI InChI=1S/C16H11Cl2N5O/c17-11-3-1-4-12(18)15(11)16(24)21-10-6-8-19-14(9-10)22-13-5-2-7-20-23-13/h1-9H,(H2,19,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439005 (CHEMBL2420830) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc2[nH]ccc12 Show InChI InChI=1S/C14H9Cl2N3O/c15-9-2-1-3-10(16)12(9)14(20)19-11-5-7-18-13-8(11)4-6-17-13/h1-7H,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439025 (CHEMBL1327969) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccncc1 Show InChI InChI=1S/C12H8Cl2N2O/c13-9-2-1-3-10(14)11(9)12(17)16-8-4-6-15-7-5-8/h1-7H,(H,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439034 (CHEMBL2420811) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(NC(=O)C2CCCO2)c1 Show InChI InChI=1S/C17H15Cl2N3O3/c18-11-3-1-4-12(19)15(11)17(24)21-10-6-7-20-14(9-10)22-16(23)13-5-2-8-25-13/h1,3-4,6-7,9,13H,2,5,8H2,(H2,20,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439032 (CHEMBL2420839) Show SMILES OCC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C14H11Cl2N3O3/c15-9-2-1-3-10(16)13(9)14(22)18-8-4-5-17-11(6-8)19-12(21)7-20/h1-6,20H,7H2,(H2,17,18,19,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439033 (CHEMBL2420817) Show SMILES Clc1cccc(Cl)c1-c1nc(c[nH]1)-c1ccncc1 Show InChI InChI=1S/C14H9Cl2N3/c15-10-2-1-3-11(16)13(10)14-18-8-12(19-14)9-4-6-17-7-5-9/h1-8H,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439010 (CHEMBL2420836) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(NC(=O)C2CCC2)c1 Show InChI InChI=1S/C17H15Cl2N3O2/c18-12-5-2-6-13(19)15(12)17(24)21-11-7-8-20-14(9-11)22-16(23)10-3-1-4-10/h2,5-10H,1,3-4H2,(H2,20,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439028 (CHEMBL2420844) Show SMILES Fc1cccc(Cl)c1C(=O)Nc1ccncc1 Show InChI InChI=1S/C12H8ClFN2O/c13-9-2-1-3-10(14)11(9)12(17)16-8-4-6-15-7-5-8/h1-7H,(H,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439031 (CHEMBL2420846) Show SMILES Nc1cccc(Cl)c1C(=O)Nc1ccncc1 Show InChI InChI=1S/C12H10ClN3O/c13-9-2-1-3-10(14)11(9)12(17)16-8-4-6-15-7-5-8/h1-7H,14H2,(H,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439030 (CHEMBL1702157) Show SMILES Clc1ccccc1C(=O)Nc1ccncc1 Show InChI InChI=1S/C12H9ClN2O/c13-11-4-2-1-3-10(11)12(16)15-9-5-7-14-8-6-9/h1-8H,(H,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439026 (CHEMBL2420851) Show SMILES Clc1ccc(Cl)c(c1)C(=O)Nc1ccncc1 Show InChI InChI=1S/C12H8Cl2N2O/c13-8-1-2-11(14)10(7-8)12(17)16-9-3-5-15-6-4-9/h1-7H,(H,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439029 (CHEMBL2420852) Show SMILES FC(F)(F)c1ccc(Cl)c(c1)C(=O)Nc1ccncc1 Show InChI InChI=1S/C13H8ClF3N2O/c14-11-2-1-8(13(15,16)17)7-10(11)12(20)19-9-3-5-18-6-4-9/h1-7H,(H,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439028 (CHEMBL2420844) Show SMILES Fc1cccc(Cl)c1C(=O)Nc1ccncc1 Show InChI InChI=1S/C12H8ClFN2O/c13-9-2-1-3-10(14)11(9)12(17)16-8-4-6-15-7-5-8/h1-7H,(H,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439027 (CHEMBL2420818) Show SMILES Clc1cccc(Cl)c1-c1nnc([nH]1)-c1ccncc1 Show InChI InChI=1S/C13H8Cl2N4/c14-9-2-1-3-10(15)11(9)13-17-12(18-19-13)8-4-6-16-7-5-8/h1-7H,(H,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439029 (CHEMBL2420852) Show SMILES FC(F)(F)c1ccc(Cl)c(c1)C(=O)Nc1ccncc1 Show InChI InChI=1S/C13H8ClF3N2O/c14-11-2-1-8(13(15,16)17)7-10(11)12(20)19-9-3-5-18-6-4-9/h1-7H,(H,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439026 (CHEMBL2420851) Show SMILES Clc1ccc(Cl)c(c1)C(=O)Nc1ccncc1 Show InChI InChI=1S/C12H8Cl2N2O/c13-8-1-2-11(14)10(7-8)12(17)16-9-3-5-15-6-4-9/h1-7H,(H,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439025 (CHEMBL1327969) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccncc1 Show InChI InChI=1S/C12H8Cl2N2O/c13-9-2-1-3-10(14)11(9)12(17)16-8-4-6-15-7-5-8/h1-7H,(H,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439023 (CHEMBL2420840) Show SMILES NCC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C14H12Cl2N4O2/c15-9-2-1-3-10(16)13(9)14(22)19-8-4-5-18-11(6-8)20-12(21)7-17/h1-6H,7,17H2,(H2,18,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439016 (CHEMBL2420832) Show SMILES CCC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C15H13Cl2N3O2/c1-2-13(21)20-12-8-9(6-7-18-12)19-15(22)14-10(16)4-3-5-11(14)17/h3-8H,2H2,1H3,(H2,18,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439024 (CHEMBL2420837) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(NC(=O)C2CCCC2)c1 Show InChI InChI=1S/C18H17Cl2N3O2/c19-13-6-3-7-14(20)16(13)18(25)22-12-8-9-21-15(10-12)23-17(24)11-4-1-2-5-11/h3,6-11H,1-2,4-5H2,(H2,21,22,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439022 (CHEMBL2420825) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(Nc2ncccn2)c1 Show InChI InChI=1S/C16H11Cl2N5O/c17-11-3-1-4-12(18)14(11)15(24)22-10-5-8-19-13(9-10)23-16-20-6-2-7-21-16/h1-9H,(H2,19,20,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439009 (CHEMBL2420813) Show SMILES COC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C14H11Cl2N3O3/c1-22-14(21)19-11-7-8(5-6-17-11)18-13(20)12-9(15)3-2-4-10(12)16/h2-7H,1H3,(H2,17,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439021 (CHEMBL2420838) Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccnc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C19H13Cl2N3O2/c20-14-7-4-8-15(21)17(14)19(26)23-13-9-10-22-16(11-13)24-18(25)12-5-2-1-3-6-12/h1-11H,(H2,22,23,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM39263 (2,6-bis(fluoranyl)-N-pyridin-4-yl-benzamide | 2,6-...) Show SMILES Fc1cccc(F)c1C(=O)Nc1ccncc1 Show InChI InChI=1S/C12H8F2N2O/c13-9-2-1-3-10(14)11(9)12(17)16-8-4-6-15-7-5-8/h1-7H,(H,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439042 (CHEMBL2420819) Show SMILES Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C12H9Cl2N3O/c13-8-2-1-3-9(14)11(8)12(18)17-7-4-5-16-10(15)6-7/h1-6H,(H3,15,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439015 (CHEMBL2420821) Show SMILES CC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C14H11Cl2N3O2/c1-8(20)18-12-7-9(5-6-17-12)19-14(21)13-10(15)3-2-4-11(13)16/h2-7H,1H3,(H2,17,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair

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