Compile Data Set for Download or QSAR

Found 19 hits Enz. Inhib. hit(s) with all data for entry = 50004402   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50235738 (Hippuristanol) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)CC[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@]1(C[C@H](C)C(C)(C)O1)O2 |r| Show InChI InChI=1S/C28H46O5/c1-15-13-28(33-24(15,2)3)27(6,31)23-21(32-28)12-19-18-8-7-16-11-17(29)9-10-25(16,4)22(18)20(30)14-26(19,23)5/h15-23,29-31H,7-14H2,1-6H3/t15-,16-,17+,18-,19-,20-,21-,22+,23-,25-,26-,27+,28+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482563 (CHEMBL449854 | Hippurin-1) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)[C@@H](C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@]1(C[C@H](C)C(C)(C)O1)O2)OC(C)=O |r| Show InChI InChI=1S/C30H48O7/c1-15-12-30(37-26(15,3)4)29(7,34)25-22(36-30)11-19-18-9-8-17-10-20(32)23(35-16(2)31)14-27(17,5)24(18)21(33)13-28(19,25)6/h15,17-25,32-34H,8-14H2,1-7H3/t15-,17-,18-,19-,20-,21-,22-,23+,24+,25-,27-,28-,29+,30+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482566 (CHEMBL1222376) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)[C@H](O)C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@]1(C[C@H](C)C(C)(C)O1)O2 |r| Show InChI InChI=1S/C28H46O6/c1-14-11-28(34-24(14,2)3)27(6,32)23-21(33-28)10-17-16-8-7-15-9-18(29)19(30)12-25(15,4)22(16)20(31)13-26(17,23)5/h14-23,29-32H,7-13H2,1-6H3/t14-,15-,16-,17-,18-,19+,20-,21-,22+,23-,25-,26-,27+,28+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482552 (CHEMBL507260) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](OC(C)=O)[C@H](O)C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@]1(C[C@H](C)C(C)(C)O1)O2 |r| Show InChI InChI=1S/C30H48O7/c1-15-12-30(37-26(15,3)4)29(7,34)25-23(36-30)11-19-18-9-8-17-10-22(35-16(2)31)20(32)13-27(17,5)24(18)21(33)14-28(19,25)6/h15,17-25,32-34H,8-14H2,1-7H3/t15-,17-,18-,19-,20+,21-,22-,23-,24+,25-,27-,28-,29+,30+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482553 (CHEMBL1222377) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)[C@@H](C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@]1(C[C@H](C)C(C)(C)O1)O2)OC(=O)CCCC(O)=O |r| Show InChI InChI=1S/C33H52O9/c1-17-14-33(42-29(17,2)3)32(6,39)28-23(41-33)13-20-19-11-10-18-12-21(34)24(40-26(38)9-7-8-25(36)37)16-30(18,4)27(19)22(35)15-31(20,28)5/h17-24,27-28,34-35,39H,7-16H2,1-6H3,(H,36,37)/t17-,18-,19-,20-,21-,22-,23-,24+,27+,28-,30-,31-,32+,33+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482550 (CHEMBL1222374 | Hippuristanol 11-One) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)CC[C@]5(C)[C@@]4([H])C(=O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@]1(C[C@H](C)C(C)(C)O1)O2 |r| Show InChI InChI=1S/C28H44O5/c1-15-13-28(33-24(15,2)3)27(6,31)23-21(32-28)12-19-18-8-7-16-11-17(29)9-10-25(16,4)22(18)20(30)14-26(19,23)5/h15-19,21-23,29,31H,7-14H2,1-6H3/t15-,16-,17+,18-,19-,21-,22+,23-,25-,26-,27+,28+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482560 (CHEMBL1222308 | Hippuristanol 3-Acetate) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@@H](CC[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@]1(C[C@H](C)C(C)(C)O1)O2)OC(C)=O |r| Show InChI InChI=1S/C30H48O6/c1-16-14-30(36-26(16,3)4)29(7,33)25-23(35-30)13-21-20-9-8-18-12-19(34-17(2)31)10-11-27(18,5)24(20)22(32)15-28(21,25)6/h16,18-25,32-33H,8-15H2,1-7H3/t16-,18-,19+,20-,21-,22-,23-,24+,25-,27-,28-,29+,30+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482559 (CHEMBL457151) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)[C@H](O)C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@@]1(C[C@H](C)C(C)(C)O1)O2 |r| Show InChI InChI=1S/C28H46O6/c1-14-11-28(34-24(14,2)3)27(6,32)23-21(33-28)10-17-16-8-7-15-9-18(29)19(30)12-25(15,4)22(16)20(31)13-26(17,23)5/h14-23,29-32H,7-13H2,1-6H3/t14-,15-,16-,17-,18-,19+,20-,21-,22+,23-,25-,26-,27+,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482565 (CHEMBL1221511) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)[C@@H](C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@@]1(C[C@H](C)C(C)(C)O1)O2)OC(=O)CCCC(O)=O |r| Show InChI InChI=1S/C33H52O9/c1-17-14-33(42-29(17,2)3)32(6,39)28-23(41-33)13-20-19-11-10-18-12-21(34)24(40-26(38)9-7-8-25(36)37)16-30(18,4)27(19)22(35)15-31(20,28)5/h17-24,27-28,34-35,39H,7-16H2,1-6H3,(H,36,37)/t17-,18-,19-,20-,21-,22-,23-,24+,27+,28-,30-,31-,32+,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482551 (CHEMBL1222375 | Hippuristanol 3,11-Dione) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])CC(=O)CC[C@]5(C)[C@@]4([H])C(=O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@]1(C[C@H](C)C(C)(C)O1)O2 |r| Show InChI InChI=1S/C28H42O5/c1-15-13-28(33-24(15,2)3)27(6,31)23-21(32-28)12-19-18-8-7-16-11-17(29)9-10-25(16,4)22(18)20(30)14-26(19,23)5/h15-16,18-19,21-23,31H,7-14H2,1-6H3/t15-,16-,18-,19-,21-,22+,23-,25-,26-,27+,28+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482557 (CHEMBL506697) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](OC(C)=O)[C@H](O)C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@@]1(C[C@H](C)C(C)(C)O1)O2 |r| Show InChI InChI=1S/C30H48O7/c1-15-12-30(37-26(15,3)4)29(7,34)25-23(36-30)11-19-18-9-8-17-10-22(35-16(2)31)20(32)13-27(17,5)24(18)21(33)14-28(19,25)6/h15,17-25,32-34H,8-14H2,1-7H3/t15-,17-,18-,19-,20+,21-,22-,23-,24+,25-,27-,28-,29+,30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482562 (CHEMBL1222309 | Hippuristanol 3,11-Diacetate) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@@H](CC[C@]5(C)[C@@]4([H])[C@H](C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@]1(C[C@H](C)C(C)(C)O1)O2)OC(C)=O)OC(C)=O |r| Show InChI InChI=1S/C32H50O7/c1-17-15-32(39-28(17,4)5)31(8,35)27-24(38-32)14-23-22-10-9-20-13-21(36-18(2)33)11-12-29(20,6)26(22)25(37-19(3)34)16-30(23,27)7/h17,20-27,35H,9-16H2,1-8H3/t17-,20-,21+,22-,23-,24-,25-,26+,27-,29-,30-,31+,32+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482558 (Hippuristanohemiacetal) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@@H](CC[C@]5(C)[C@@]4([H])[C@@H](O)C[C@@]33[C@H](O)O[C@](C)([C@@]13[H])[C@@]1(C[C@H](C)C(C)(C)O1)O2)OC(C)=O |r| Show InChI InChI=1S/C30H46O7/c1-15-13-30(37-26(15,3)4)28(6)24-22(35-30)12-20-19-8-7-17-11-18(34-16(2)31)9-10-27(17,5)23(19)21(32)14-29(20,24)25(33)36-28/h15,17-25,32-33H,7-14H2,1-6H3/t15-,17-,18+,19-,20-,21-,22-,23+,24+,25+,27-,28+,29+,30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482561 (CHEMBL1221461 | Epihippuristanol 3,11-Diacetate) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@@H](CC[C@]5(C)[C@@]4([H])[C@H](C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@@]1(C[C@H](C)C(C)(C)O1)O2)OC(C)=O)OC(C)=O |r| Show InChI InChI=1S/C32H50O7/c1-17-15-32(39-28(17,4)5)31(8,35)27-24(38-32)14-23-22-10-9-20-13-21(36-18(2)33)11-12-29(20,6)26(22)25(37-19(3)34)16-30(23,27)7/h17,20-27,35H,9-16H2,1-8H3/t17-,20-,21+,22-,23-,24-,25-,26+,27-,29-,30-,31+,32-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482556 (Epihippurin 1) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)[C@@H](C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@@]1(C[C@H](C)C(C)(C)O1)O2)OC(C)=O |r| Show InChI InChI=1S/C30H48O7/c1-15-12-30(37-26(15,3)4)29(7,34)25-22(36-30)11-19-18-9-8-17-10-20(32)23(35-16(2)31)14-27(17,5)24(18)21(33)13-28(19,25)6/h15,17-25,32-34H,8-14H2,1-7H3/t15-,17-,18-,19-,20-,21-,22-,23+,24+,25-,27-,28-,29+,30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482554 (CHEMBL1221460 | Epihippuristanol 3-Acetate) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@@H](CC[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@@]1(C[C@H](C)C(C)(C)O1)O2)OC(C)=O |r| Show InChI InChI=1S/C30H48O6/c1-16-14-30(36-26(16,3)4)29(7,33)25-23(35-30)13-21-20-9-8-18-12-19(34-17(2)31)10-11-27(18,5)24(20)22(32)15-28(21,25)6/h16,18-25,32-33H,8-15H2,1-7H3/t16-,18-,19+,20-,21-,22-,23-,24+,25-,27-,28-,29+,30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482564 (CHEMBL1221464 | Epihippuristanol 3,11-Dione) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])CC(=O)CC[C@]5(C)[C@@]4([H])C(=O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@@]1(C[C@H](C)C(C)(C)O1)O2 |r| Show InChI InChI=1S/C28H42O5/c1-15-13-28(33-24(15,2)3)27(6,31)23-21(32-28)12-19-18-8-7-16-11-17(29)9-10-25(16,4)22(18)20(30)14-26(19,23)5/h15-16,18-19,21-23,31H,7-14H2,1-6H3/t15-,16-,18-,19-,21-,22+,23-,25-,26-,27+,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482567 (22-Epi-Hippuristanol | Epihippuristanol) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)CC[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@@]1(C[C@H](C)C(C)(C)O1)O2 |r| Show InChI InChI=1S/C28H46O5/c1-15-13-28(33-24(15,2)3)27(6,31)23-21(32-28)12-19-18-8-7-16-11-17(29)9-10-25(16,4)22(18)20(30)14-26(19,23)5/h15-23,29-31H,7-14H2,1-6H3/t15-,16-,17+,18-,19-,20-,21-,22+,23-,25-,26-,27+,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482555 (CHEMBL1221463 | Epihippuristanol 11-One) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)CC[C@]5(C)[C@@]4([H])C(=O)C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@@]1(C[C@H](C)C(C)(C)O1)O2 |r| Show InChI InChI=1S/C28H44O5/c1-15-13-28(33-24(15,2)3)27(6,31)23-21(32-28)12-19-18-8-7-16-11-17(29)9-10-25(16,4)22(18)20(30)14-26(19,23)5/h15-19,21-23,29,31H,7-14H2,1-6H3/t15-,16-,17+,18-,19-,21-,22+,23-,25-,26-,27+,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
					More data for this Ligand-Target Pair