Compile Data Set for Download or QSAR

Found 88 hits Enz. Inhib. hit(s) with all data for entry = 50006387   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50499430 (CHEMBL3740472) Show SMILES [H][C@@]12CN(CCCOC)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C21H30N4O2/c1-14(2)20-23-19(18-7-4-5-9-25(18)20)21(26)22-11-15-16-12-24(13-17(15)16)8-6-10-27-3/h4-5,7,9,14-17H,6,8,10-13H2,1-3H3,(H,22,26)/t15-,16-,17+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins by LC-MS/MS analysis in presence of NADPH regeneration syste...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50499447 (CHEMBL3739521) Show SMILES CC(C)N1CCC(CC1)NC(=O)c1nc(C(C)C)n2ccccc12 Show InChI InChI=1S/C19H28N4O/c1-13(2)18-21-17(16-7-5-6-10-23(16)18)19(24)20-15-8-11-22(12-9-15)14(3)4/h5-7,10,13-15H,8-9,11-12H2,1-4H3,(H,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins by LC-MS/MS analysis in presence of NADPH regeneration syste...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50499430 (CHEMBL3740472) Show SMILES [H][C@@]12CN(CCCOC)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C21H30N4O2/c1-14(2)20-23-19(18-7-4-5-9-25(18)20)21(26)22-11-15-16-12-24(13-17(15)16)8-6-10-27-3/h4-5,7,9,14-17H,6,8,10-13H2,1-3H3,(H,22,26)/t15-,16-,17+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of human ERG channel expressed in HEK293 cells after 5 mins by patch clamp assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50499445 (CHEMBL3741608) Show SMILES CC(C)c1nc(C(=O)NCC2CCN(CC3CCOCC3)CC2)c2ccccn12 Show InChI InChI=1S/C23H34N4O2/c1-17(2)22-25-21(20-5-3-4-10-27(20)22)23(28)24-15-18-6-11-26(12-7-18)16-19-8-13-29-14-9-19/h3-5,10,17-19H,6-9,11-16H2,1-2H3,(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins by LC-MS/MS analysis in presence of NADPH regenerati...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50499450 (CHEMBL3741776) Show SMILES COCCCN1CCC(CC1)NC(=O)c1nc(C(C)C)n2ccccc12 Show InChI InChI=1S/C20H30N4O2/c1-15(2)19-22-18(17-7-4-5-11-24(17)19)20(25)21-16-8-12-23(13-9-16)10-6-14-26-3/h4-5,7,11,15-16H,6,8-10,12-14H2,1-3H3,(H,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins by LC-MS/MS analysis in presence of NADPH regeneration syste...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50499428 (CHEMBL3741377) Show SMILES [H][C@@]12CN(CC(C)(C)O)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C21H30N4O2/c1-13(2)19-23-18(17-7-5-6-8-25(17)19)20(26)22-9-14-15-10-24(11-16(14)15)12-21(3,4)27/h5-8,13-16,27H,9-12H2,1-4H3,(H,22,26)/t14-,15-,16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins by LC-MS/MS analysis in presence of NADPH regeneration syste...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50499437 (CHEMBL3739470) Show SMILES CC(C)c1nc(C(=O)NC2CCN(CC3CC3)CC2)c2ccccn12 Show InChI InChI=1S/C20H28N4O/c1-14(2)19-22-18(17-5-3-4-10-24(17)19)20(25)21-16-8-11-23(12-9-16)13-15-6-7-15/h3-5,10,14-16H,6-9,11-13H2,1-2H3,(H,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins by LC-MS/MS analysis in presence of NADPH regeneration syste...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50499430 (CHEMBL3740472) Show SMILES [H][C@@]12CN(CCCOC)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C21H30N4O2/c1-14(2)20-23-19(18-7-4-5-9-25(18)20)21(26)22-11-15-16-12-24(13-17(15)16)8-6-10-27-3/h4-5,7,9,14-17H,6,8,10-13H2,1-3H3,(H,22,26)/t15-,16-,17+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins by LC-MS/MS analysis in presence of NADPH regenerati...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50499445 (CHEMBL3741608) Show SMILES CC(C)c1nc(C(=O)NCC2CCN(CC3CCOCC3)CC2)c2ccccn12 Show InChI InChI=1S/C23H34N4O2/c1-17(2)22-25-21(20-5-3-4-10-27(20)22)23(28)24-15-18-6-11-26(12-7-18)16-19-8-13-29-14-9-19/h3-5,10,17-19H,6-9,11-16H2,1-2H3,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins by LC-MS/MS analysis in presence of NADPH regeneration syste...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50499455 (CHEMBL3741821) Show SMILES COCCCN1CCC(CNC(=O)c2nc(C(C)C)n3ccccc23)CC1 Show InChI InChI=1S/C21H32N4O2/c1-16(2)20-23-19(18-7-4-5-11-25(18)20)21(26)22-15-17-8-12-24(13-9-17)10-6-14-27-3/h4-5,7,11,16-17H,6,8-10,12-15H2,1-3H3,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins by LC-MS/MS analysis in presence of NADPH regeneration syste...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50499448 (CHEMBL3740908) Show SMILES CC(C)c1nc(C(=O)NC2CCN(CCF)CC2)c2ccccn12 Show InChI InChI=1S/C18H25FN4O/c1-13(2)17-21-16(15-5-3-4-9-23(15)17)18(24)20-14-6-10-22(11-7-14)12-8-19/h3-5,9,13-14H,6-8,10-12H2,1-2H3,(H,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins by LC-MS/MS analysis in presence of NADPH regeneration syste...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50499450 (CHEMBL3741776) Show SMILES COCCCN1CCC(CC1)NC(=O)c1nc(C(C)C)n2ccccc12 Show InChI InChI=1S/C20H30N4O2/c1-15(2)19-22-18(17-7-4-5-11-24(17)19)20(25)21-16-8-12-23(13-9-16)10-6-14-26-3/h4-5,7,11,15-16H,6,8-10,12-14H2,1-3H3,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins by LC-MS/MS analysis in presence of NADPH regenerati...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50499434 (CHEMBL3739647) Show SMILES [H][C@@]12CN(CC3CCOCC3)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C23H32N4O2/c1-15(2)22-25-21(20-5-3-4-8-27(20)22)23(28)24-11-17-18-13-26(14-19(17)18)12-16-6-9-29-10-7-16/h3-5,8,15-19H,6-7,9-14H2,1-2H3,(H,24,28)/t17-,18-,19+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins by LC-MS/MS analysis in presence of NADPH regeneration syste...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50499428 (CHEMBL3741377) Show SMILES [H][C@@]12CN(CC(C)(C)O)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C21H30N4O2/c1-13(2)19-23-18(17-7-5-6-8-25(17)19)20(26)22-9-14-15-10-24(11-16(14)15)12-21(3,4)27/h5-8,13-16,27H,9-12H2,1-4H3,(H,22,26)/t14-,15-,16+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins by LC-MS/MS analysis in presence of NADPH regenerati...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50499432 (CHEMBL3741595) Show SMILES [H][C@@]12CN(CC(C)(C)F)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C21H29FN4O/c1-13(2)19-24-18(17-7-5-6-8-26(17)19)20(27)23-9-14-15-10-25(11-16(14)15)12-21(3,4)22/h5-8,13-16H,9-12H2,1-4H3,(H,23,27)/t14-,15-,16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins by LC-MS/MS analysis in presence of NADPH regeneration syste...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50499455 (CHEMBL3741821) Show SMILES COCCCN1CCC(CNC(=O)c2nc(C(C)C)n3ccccc23)CC1 Show InChI InChI=1S/C21H32N4O2/c1-16(2)20-23-19(18-7-4-5-11-25(18)20)21(26)22-15-17-8-12-24(13-9-17)10-6-14-27-3/h4-5,7,11,16-17H,6,8-10,12-15H2,1-3H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins by LC-MS/MS analysis in presence of NADPH regenerati...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50499447 (CHEMBL3739521) Show SMILES CC(C)N1CCC(CC1)NC(=O)c1nc(C(C)C)n2ccccc12 Show InChI InChI=1S/C19H28N4O/c1-13(2)18-21-17(16-7-5-6-10-23(16)18)19(24)20-15-8-11-22(12-9-15)14(3)4/h5-7,10,13-15H,8-9,11-12H2,1-4H3,(H,20,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins by LC-MS/MS analysis in presence of NADPH regenerati...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50499446 (CHEMBL3740669) Show SMILES [H][C@@]12CN(CC3CCN(CC3)C(=O)OC)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C25H35N5O3/c1-16(2)23-27-22(21-6-4-5-9-30(21)23)24(31)26-12-18-19-14-28(15-20(18)19)13-17-7-10-29(11-8-17)25(32)33-3/h4-6,9,16-20H,7-8,10-15H2,1-3H3,(H,26,31)/t18-,19-,20+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins by LC-MS/MS analysis in presence of NADPH regeneration syste...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50499446 (CHEMBL3740669) Show SMILES [H][C@@]12CN(CC3CCN(CC3)C(=O)OC)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C25H35N5O3/c1-16(2)23-27-22(21-6-4-5-9-30(21)23)24(31)26-12-18-19-14-28(15-20(18)19)13-17-7-10-29(11-8-17)25(32)33-3/h4-6,9,16-20H,7-8,10-15H2,1-3H3,(H,26,31)/t18-,19-,20+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins by LC-MS/MS analysis in presence of NADPH regenerati...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50499434 (CHEMBL3739647) Show SMILES [H][C@@]12CN(CC3CCOCC3)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C23H32N4O2/c1-15(2)22-25-21(20-5-3-4-8-27(20)22)23(28)24-11-17-18-13-26(14-19(17)18)12-16-6-9-29-10-7-16/h3-5,8,15-19H,6-7,9-14H2,1-2H3,(H,24,28)/t17-,18-,19+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins by LC-MS/MS analysis in presence of NADPH regenerati...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50499448 (CHEMBL3740908) Show SMILES CC(C)c1nc(C(=O)NC2CCN(CCF)CC2)c2ccccn12 Show InChI InChI=1S/C18H25FN4O/c1-13(2)17-21-16(15-5-3-4-9-23(15)17)18(24)20-14-6-10-22(11-7-14)12-8-19/h3-5,9,13-14H,6-8,10-12H2,1-2H3,(H,20,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins by LC-MS/MS analysis in presence of NADPH regenerati...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50499437 (CHEMBL3739470) Show SMILES CC(C)c1nc(C(=O)NC2CCN(CC3CC3)CC2)c2ccccn12 Show InChI InChI=1S/C20H28N4O/c1-14(2)19-22-18(17-5-3-4-10-24(17)19)20(25)21-16-8-11-23(12-9-16)13-15-6-7-15/h3-5,10,14-16H,6-9,11-13H2,1-2H3,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins by LC-MS/MS analysis in presence of NADPH regenerati...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50499432 (CHEMBL3741595) Show SMILES [H][C@@]12CN(CC(C)(C)F)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C21H29FN4O/c1-13(2)19-24-18(17-7-5-6-8-26(17)19)20(27)23-9-14-15-10-25(11-16(14)15)12-21(3,4)22/h5-8,13-16H,9-12H2,1-4H3,(H,23,27)/t14-,15-,16+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.34E+5	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins by LC-MS/MS analysis in presence of NADPH regenerati...				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499437 (CHEMBL3739470) Show SMILES CC(C)c1nc(C(=O)NC2CCN(CC3CC3)CC2)c2ccccn12 Show InChI InChI=1S/C20H28N4O/c1-14(2)19-22-18(17-5-3-4-10-24(17)19)20(25)21-16-8-11-23(12-9-16)13-15-6-7-15/h3-5,10,14-16H,6-9,11-13H2,1-2H3,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499438 (CHEMBL3739467) Show SMILES COCCCN1CCC(CC1)c1nnc(o1)-c1nc(C(C)C)n2ccccc12 Show InChI InChI=1S/C21H29N5O2/c1-15(2)19-22-18(17-7-4-5-11-26(17)19)21-24-23-20(28-21)16-8-12-25(13-9-16)10-6-14-27-3/h4-5,7,11,15-16H,6,8-10,12-14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	736	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499439 (CHEMBL3740000) Show SMILES CC(C)c1nc(-c2nnc(o2)C2CCN(CC3CC3)CC2)c2ccccn12 Show InChI InChI=1S/C21H27N5O/c1-14(2)19-22-18(17-5-3-4-10-26(17)19)21-24-23-20(27-21)16-8-11-25(12-9-16)13-15-6-7-15/h3-5,10,14-16H,6-9,11-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	857	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499440 (CHEMBL3741062) Show SMILES CC(C)c1nc(C(=O)NCC2(C)CCN(CC3CCOCC3)CC2)c2ccccn12 Show InChI InChI=1S/C24H36N4O2/c1-18(2)22-26-21(20-6-4-5-11-28(20)22)23(29)25-17-24(3)9-12-27(13-10-24)16-19-7-14-30-15-8-19/h4-6,11,18-19H,7-10,12-17H2,1-3H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499441 (CHEMBL3739459) Show SMILES CC(C)c1nc(C(=O)NCC2(O)CCN(CC3CCOCC3)CC2)c2ccccn12 Show InChI InChI=1S/C23H34N4O3/c1-17(2)21-25-20(19-5-3-4-10-27(19)21)22(28)24-16-23(29)8-11-26(12-9-23)15-18-6-13-30-14-7-18/h3-5,10,17-18,29H,6-9,11-16H2,1-2H3,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499442 (CHEMBL3740278) Show SMILES CC(C)c1nc(C(=O)NCC2(F)CCN(CC3CCOCC3)CC2)c2ccccn12 Show InChI InChI=1S/C23H33FN4O2/c1-17(2)21-26-20(19-5-3-4-10-28(19)21)22(29)25-16-23(24)8-11-27(12-9-23)15-18-6-13-30-14-7-18/h3-5,10,17-18H,6-9,11-16H2,1-2H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499443 (CHEMBL3740864) Show SMILES COCCCN1CCC(F)(CNC(=O)c2nc(C(C)C)n3ccccc23)CC1 Show InChI InChI=1S/C21H31FN4O2/c1-16(2)19-24-18(17-7-4-5-11-26(17)19)20(27)23-15-21(22)8-12-25(13-9-21)10-6-14-28-3/h4-5,7,11,16H,6,8-10,12-15H2,1-3H3,(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	633	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499444 (CHEMBL3741733) Show SMILES CC(C)c1nc(C(=O)NCC2CCN(CC2)C2CCC2)c2ccccn12 Show InChI InChI=1S/C21H30N4O/c1-15(2)20-23-19(18-8-3-4-11-25(18)20)21(26)22-14-16-9-12-24(13-10-16)17-6-5-7-17/h3-4,8,11,15-17H,5-7,9-10,12-14H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499445 (CHEMBL3741608) Show SMILES CC(C)c1nc(C(=O)NCC2CCN(CC3CCOCC3)CC2)c2ccccn12 Show InChI InChI=1S/C23H34N4O2/c1-17(2)22-25-21(20-5-3-4-10-27(20)22)23(28)24-15-18-6-11-26(12-7-18)16-19-8-13-29-14-9-19/h3-5,10,17-19H,6-9,11-16H2,1-2H3,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499430 (CHEMBL3740472) Show SMILES [H][C@@]12CN(CCCOC)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C21H30N4O2/c1-14(2)20-23-19(18-7-4-5-9-25(18)20)21(26)22-11-15-16-12-24(13-17(15)16)8-6-10-27-3/h4-5,7,9,14-17H,6,8,10-13H2,1-3H3,(H,22,26)/t15-,16-,17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5-HT4A receptor assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499430 (CHEMBL3740472) Show SMILES [H][C@@]12CN(CCCOC)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C21H30N4O2/c1-14(2)20-23-19(18-7-4-5-9-25(18)20)21(26)22-11-15-16-12-24(13-17(15)16)8-6-10-27-3/h4-5,7,9,14-17H,6,8,10-13H2,1-3H3,(H,22,26)/t15-,16-,17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5-HT4D receptor assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50436989 (CHEMBL2402904) Show SMILES COC(=O)N1CCC(CN2CCC(CNC(=O)c3cccc4nc([nH]c34)C(C)C)CC2)CC1 Show InChI InChI=1S/C25H37N5O3/c1-17(2)23-27-21-6-4-5-20(22(21)28-23)24(31)26-15-18-7-11-29(12-8-18)16-19-9-13-30(14-10-19)25(32)33-3/h4-6,17-19H,7-16H2,1-3H3,(H,26,31)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.60	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at 5-HT4 receptor in guinea pig colon				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (RAT)	BDBM84950 (CAS_183782 | NSC_183782 | RS 67333) Show SMILES CCCCN1CCC(CCC(=O)c2cc(Cl)c(N)cc2OC)CC1 Show InChI InChI=1S/C19H29ClN2O2/c1-3-4-9-22-10-7-14(8-11-22)5-6-18(23)15-12-16(20)17(21)13-19(15)24-2/h12-14H,3-11,21H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8.70	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at 5-HT4 receptor in Sprague-Dawley rat oesophagus assessed as relaxation of carbachol precontracted oesophagus				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(N)c2CCOc12 Show InChI InChI=1S/C18H26ClN3O3/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (RAT)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at 5HT2b receptor in Wistar rat fundus measured for 90 secs				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM29526 (2-Piperidinoethyl 4-amino-5-chloro-2-methoxybenzoa...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCCCC1 Show InChI InChI=1S/C15H21ClN2O3/c1-20-14-10-13(17)12(16)9-11(14)15(19)21-8-7-18-5-3-2-4-6-18/h9-10H,2-8,17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at 5-HT4 receptor in guinea pig ileum assessed as increase in response to electrical stimulation				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499449 (CHEMBL3742086) Show SMILES CC(C)c1nc(C(=O)NC2CCN(CC(C)(C)F)CC2)c2ccccn12 Show InChI InChI=1S/C20H29FN4O/c1-14(2)18-23-17(16-7-5-6-10-25(16)18)19(26)22-15-8-11-24(12-9-15)13-20(3,4)21/h5-7,10,14-15H,8-9,11-13H2,1-4H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	132	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499450 (CHEMBL3741776) Show SMILES COCCCN1CCC(CC1)NC(=O)c1nc(C(C)C)n2ccccc12 Show InChI InChI=1S/C20H30N4O2/c1-15(2)19-22-18(17-7-4-5-11-24(17)19)20(25)21-16-8-12-23(13-9-16)10-6-14-26-3/h4-5,7,11,15-16H,6,8-10,12-14H2,1-3H3,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499447 (CHEMBL3739521) Show SMILES CC(C)N1CCC(CC1)NC(=O)c1nc(C(C)C)n2ccccc12 Show InChI InChI=1S/C19H28N4O/c1-13(2)18-21-17(16-7-5-6-10-23(16)18)19(24)20-15-8-11-22(12-9-15)14(3)4/h5-7,10,13-15H,8-9,11-12H2,1-4H3,(H,20,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.40	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499451 (CHEMBL3741199) Show SMILES CC(C)c1nc(-c2nnc(o2)C2CCN(CC2)C2CCC2)c2ccccn12 Show InChI InChI=1S/C21H27N5O/c1-14(2)19-22-18(17-8-3-4-11-26(17)19)21-24-23-20(27-21)15-9-12-25(13-10-15)16-6-5-7-16/h3-4,8,11,14-16H,5-7,9-10,12-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	840	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499452 (CHEMBL3740030) Show SMILES COCCCN1CCC(O)(CNC(=O)c2nc(C(C)C)n3ccccc23)CC1 Show InChI InChI=1S/C21H32N4O3/c1-16(2)19-23-18(17-7-4-5-11-25(17)19)20(26)22-15-21(27)8-12-24(13-9-21)10-6-14-28-3/h4-5,7,11,16,27H,6,8-10,12-15H2,1-3H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499453 (CHEMBL3742190) Show SMILES COCCN1CCC(CC1)NC(=O)c1nc(C(C)C)n2ccccc12 Show InChI InChI=1S/C19H28N4O2/c1-14(2)18-21-17(16-6-4-5-9-23(16)18)19(24)20-15-7-10-22(11-8-15)12-13-25-3/h4-6,9,14-15H,7-8,10-13H2,1-3H3,(H,20,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	144	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499454 (CHEMBL3742145) Show SMILES CC(C)c1nc(C(=O)NCC2(O)CCN(CC(C)(C)O)CC2)c2ccccn12 Show InChI InChI=1S/C21H32N4O3/c1-15(2)18-23-17(16-7-5-6-10-25(16)18)19(26)22-13-21(28)8-11-24(12-9-21)14-20(3,4)27/h5-7,10,15,27-28H,8-9,11-14H2,1-4H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	72	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499456 (CHEMBL3741548) Show SMILES [H][C@@]12CN(CC(C)(C)CO)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C22H32N4O2/c1-14(2)20-24-19(18-7-5-6-8-26(18)20)21(28)23-9-15-16-10-25(11-17(15)16)12-22(3,4)13-27/h5-8,14-17,27H,9-13H2,1-4H3,(H,23,28)/t15-,16-,17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM84950 (CAS_183782 | NSC_183782 | RS 67333) Show SMILES CCCCN1CCC(CCC(=O)c2cc(Cl)c(N)cc2OC)CC1 Show InChI InChI=1S/C19H29ClN2O2/c1-3-4-9-22-10-7-14(8-11-22)5-6-18(23)15-12-16(20)17(21)13-19(15)24-2/h12-14H,3-11,21H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499446 (CHEMBL3740669) Show SMILES [H][C@@]12CN(CC3CCN(CC3)C(=O)OC)C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12 |r| Show InChI InChI=1S/C25H35N5O3/c1-16(2)23-27-22(21-6-4-5-9-30(21)23)24(31)26-12-18-19-14-28(15-20(18)19)13-17-7-10-29(11-8-17)25(32)33-3/h4-6,9,16-20H,7-8,10-15H2,1-3H3,(H,26,31)/t18-,19-,20+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.70	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50499457 (CHEMBL3741787) Show SMILES [H][C@@]12CN(C[C@]1([H])[C@H]2CNC(=O)c1nc(C(C)C)n2ccccc12)C1CCN(CC1)C(=O)OC |r| Show InChI InChI=1S/C24H33N5O3/c1-15(2)22-26-21(20-6-4-5-9-29(20)22)23(30)25-12-17-18-13-28(14-19(17)18)16-7-10-27(11-8-16)24(31)32-3/h4-6,9,15-19H,7-8,10-14H2,1-3H3,(H,25,30)/t17-,18-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.70	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair

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