Found 42 hits Enz. Inhib. hit(s) with all data for entry = 50006809 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503606
(CHEMBL4462756)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2cc(ccc12)C(O)=O)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C27H26N2O5/c30-19-6-4-14-10-20-27(33)11-17-16-5-3-15(25(31)32)9-18(16)28-22(17)24-26(27,21(14)23(19)34-24)7-8-29(20)12-13-1-2-13/h3-6,9,13,20,24,28,30,33H,1-2,7-8,10-12H2,(H,31,32)/t20-,24+,26+,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503604
(Naldemedine | S-297995)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)(C)c1nc(no1)-c1ccccc1)=C2O)ccc3O |r,c:43| Show InChI InChI=1S/C32H34N4O6/c1-30(2,29-33-27(35-42-29)18-6-4-3-5-7-18)34-28(39)20-15-32(40)22-14-19-10-11-21(37)25-23(19)31(32,26(41-25)24(20)38)12-13-36(22)16-17-8-9-17/h3-7,10-11,17,22,26,37-38,40H,8-9,12-16H2,1-2H3,(H,34,39)/t22-,26+,31+,32-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 0.910 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503597
(CHEMBL4534307)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(C)=O)=C2O)ccc3O |r,c:27,THB:10:9:17:4.5.6| Show InChI InChI=1S/C22H25NO5/c1-11(24)14-9-22(27)16-8-13-4-5-15(25)19-17(13)21(22,20(28-19)18(14)26)6-7-23(16)10-12-2-3-12/h4-5,12,16,20,25-27H,2-3,6-10H2,1H3/t16-,20+,21+,22-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503601
(CHEMBL4529950)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)Nc1ccccc1)=C2O)ccc3O |r,c:34,THB:10:9:17:4.5.6| Show InChI InChI=1S/C27H28N2O5/c30-19-9-8-16-12-20-27(33)13-18(25(32)28-17-4-2-1-3-5-17)22(31)24-26(27,21(16)23(19)34-24)10-11-29(20)14-15-6-7-15/h1-5,8-9,15,20,24,30-31,33H,6-7,10-14H2,(H,28,32)/t20-,24+,26+,27-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503611
(CHEMBL4468216)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2c(Cl)c(ccc12)C(O)=O)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C27H25ClN2O5/c28-20-15(25(32)33)5-4-14-16-10-27(34)18-9-13-3-6-17(31)23-19(13)26(27,7-8-30(18)11-12-1-2-12)24(35-23)22(16)29-21(14)20/h3-6,12,18,24,29,31,34H,1-2,7-11H2,(H,32,33)/t18-,24+,26+,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503604
(Naldemedine | S-297995)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)(C)c1nc(no1)-c1ccccc1)=C2O)ccc3O |r,c:43| Show InChI InChI=1S/C32H34N4O6/c1-30(2,29-33-27(35-42-29)18-6-4-3-5-7-18)34-28(39)20-15-32(40)22-14-19-10-11-21(37)25-23(19)31(32,26(41-25)24(20)38)12-13-36(22)16-17-8-9-17/h3-7,10-11,17,22,26,37-38,40H,8-9,12-16H2,1-2H3,(H,34,39)/t22-,26+,31+,32-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503596
(CHEMBL4561876)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NCc1ccccc1)=C2O)ccc3O |r,c:35,THB:10:9:17:4.5.6| Show InChI InChI=1S/C28H30N2O5/c31-20-9-8-18-12-21-28(34)13-19(26(33)29-14-16-4-2-1-3-5-16)23(32)25-27(28,22(18)24(20)35-25)10-11-30(21)15-17-6-7-17/h1-5,8-9,17,21,25,31-32,34H,6-7,10-15H2,(H,29,33)/t21-,25+,27+,28-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503599
(CHEMBL4439770)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c(C)n[nH]c21)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C22H25N3O3/c1-11-14-9-22(27)16-8-13-4-5-15(26)19-17(13)21(22,20(28-19)18(14)24-23-11)6-7-25(16)10-12-2-3-12/h4-5,12,16,20,26-27H,2-3,6-10H2,1H3,(H,23,24)/t16-,20+,21+,22-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503598
(CHEMBL4551066)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)CC)=C2O)ccc3O |r,c:28,THB:10:9:17:4.5.6| Show InChI InChI=1S/C23H27NO5/c1-2-15(25)14-10-23(28)17-9-13-5-6-16(26)20-18(13)22(23,21(29-20)19(14)27)7-8-24(17)11-12-3-4-12/h5-6,12,17,21,26-28H,2-4,7-11H2,1H3/t17-,21+,22+,23-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM102406
(US8536192, I-135)Show SMILES COC(=O)C1(CC1)NC(=O)C1=C(O)[C@@H]2Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]24[C@@]5(O)C1)ccc3O |r,c:11,TLB:21:20:28:16.17.18| Show InChI InChI=1S/C26H30N2O7/c1-34-23(32)24(6-7-24)27-22(31)15-11-26(33)17-10-14-4-5-16(29)20-18(14)25(26,21(35-20)19(15)30)8-9-28(17)12-13-2-3-13/h4-5,13,17,21,29-30,33H,2-3,6-12H2,1H3,(H,27,31)/t17-,21+,25+,26-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503600
(CHEMBL4542825)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)C)=C2O)ccc3O |r,c:30,THB:10:9:17:4.5.6| Show InChI InChI=1S/C24H30N2O5/c1-12(2)25-22(29)15-10-24(30)17-9-14-5-6-16(27)20-18(14)23(24,21(31-20)19(15)28)7-8-26(17)11-13-3-4-13/h5-6,12-13,17,21,27-28,30H,3-4,7-11H2,1-2H3,(H,25,29)/t17-,21+,23+,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503610
(CHEMBL4516674)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c(C)nc(N)nc21)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C23H26N4O3/c1-11-14-9-23(29)16-8-13-4-5-15(28)19-17(13)22(23,6-7-27(16)10-12-2-3-12)20(30-19)18(14)26-21(24)25-11/h4-5,12,16,20,28-29H,2-3,6-10H2,1H3,(H2,24,25,26)/t16-,20+,22+,23-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503594
(CHEMBL4574150)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)Nc1ccc4cc[nH]c4c1)=C2O)ccc3O |r,c:38,THB:10:9:17:4.5.6| Show InChI InChI=1S/C29H29N3O5/c33-21-6-4-17-11-22-29(36)13-19(27(35)31-18-5-3-16-7-9-30-20(16)12-18)24(34)26-28(29,23(17)25(21)37-26)8-10-32(22)14-15-1-2-15/h3-7,9,12,15,22,26,30,33-34,36H,1-2,8,10-11,13-14H2,(H,31,35)/t22-,26+,28+,29-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503600
(CHEMBL4542825)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)C)=C2O)ccc3O |r,c:30,THB:10:9:17:4.5.6| Show InChI InChI=1S/C24H30N2O5/c1-12(2)25-22(29)15-10-24(30)17-9-14-5-6-16(27)20-18(14)23(24,21(31-20)19(15)28)7-8-26(17)11-13-3-4-13/h5-6,12-13,17,21,27-28,30H,3-4,7-11H2,1-2H3,(H,25,29)/t17-,21+,23+,24-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503612
(CHEMBL4459343)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)(C)C(=O)OC)=C2O)ccc3O |r,c:34,THB:10:9:17:4.5.6| Show InChI InChI=1S/C26H32N2O7/c1-24(2,23(32)34-3)27-22(31)15-11-26(33)17-10-14-6-7-16(29)20-18(14)25(26,21(35-20)19(15)30)8-9-28(17)12-13-4-5-13/h6-7,13,17,21,29-30,33H,4-5,8-12H2,1-3H3,(H,27,31)/t17-,21+,25+,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503607
(CHEMBL4452187)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)N1CCCC1)=C2O)ccc3O |r,c:32,THB:10:9:17:4.5.6| Show InChI InChI=1S/C25H30N2O5/c28-17-6-5-15-11-18-25(31)12-16(23(30)26-8-1-2-9-26)20(29)22-24(25,19(15)21(17)32-22)7-10-27(18)13-14-3-4-14/h5-6,14,18,22,28-29,31H,1-4,7-13H2/t18-,22+,24+,25-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503605
(CHEMBL4457877)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)Nc1ccc(cc1)C#N)=C2O)ccc3O |r,c:36,THB:10:9:17:4.5.6| Show InChI InChI=1S/C28H27N3O5/c29-13-15-3-6-18(7-4-15)30-26(34)19-12-28(35)21-11-17-5-8-20(32)24-22(17)27(28,25(36-24)23(19)33)9-10-31(21)14-16-1-2-16/h3-8,16,21,25,32-33,35H,1-2,9-12,14H2,(H,30,34)/t21-,25+,27+,28-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50278337
(CHEMBL470617 | Naltrexone methiodide)Show SMILES C[N+]1(CC2CC2)CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CCC4=O)ccc5O |r| Show InChI InChI=1S/C21H25NO4/c1-22(11-12-2-3-12)9-8-20-17-13-4-5-14(23)18(17)26-19(20)15(24)6-7-21(20,25)16(22)10-13/h4-5,12,16,19,25H,2-3,6-11H2,1H3/p+1/t16-,19+,20+,21-,22?/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Similars
| DrugBank
Article
PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503602
(CHEMBL4472077)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)(C)C(=O)NS(C)(=O)=O)=C2O)ccc3O |r,c:37,THB:10:9:17:4.5.6| Show InChI InChI=1S/C26H33N3O8S/c1-24(2,23(33)28-38(3,35)36)27-22(32)15-11-26(34)17-10-14-6-7-16(30)20-18(14)25(26,21(37-20)19(15)31)8-9-29(17)12-13-4-5-13/h6-7,13,17,21,30-31,34H,4-5,8-12H2,1-3H3,(H,27,32)(H,28,33)/t17-,21+,25+,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503608
(CHEMBL4445736)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)(C)c1nc(C)no1)=C2O)ccc3O |r,c:37,THB:10:9:17:4.5.6| Show InChI InChI=1S/C27H32N4O6/c1-13-28-24(37-30-13)25(2,3)29-23(34)16-11-27(35)18-10-15-6-7-17(32)21-19(15)26(27,22(36-21)20(16)33)8-9-31(18)12-14-4-5-14/h6-7,14,18,22,32-33,35H,4-5,8-12H2,1-3H3,(H,29,34)/t18-,22+,26+,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503609
(CHEMBL4543425)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)Nc1ccccn1)=C2O)ccc3O |r,c:34,THB:10:9:17:4.5.6| Show InChI InChI=1S/C26H27N3O5/c30-17-7-6-15-11-18-26(33)12-16(24(32)28-19-3-1-2-9-27-19)21(31)23-25(26,20(15)22(17)34-23)8-10-29(18)13-14-4-5-14/h1-3,6-7,9,14,18,23,30-31,33H,4-5,8,10-13H2,(H,27,28,32)/t18-,23+,25+,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503601
(CHEMBL4529950)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)Nc1ccccc1)=C2O)ccc3O |r,c:34,THB:10:9:17:4.5.6| Show InChI InChI=1S/C27H28N2O5/c30-19-9-8-16-12-20-27(33)13-18(25(32)28-17-4-2-1-3-5-17)22(31)24-26(27,21(16)23(19)34-24)10-11-29(20)14-15-6-7-15/h1-5,8-9,15,20,24,30-31,33H,6-7,10-14H2,(H,28,32)/t20-,24+,26+,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503608
(CHEMBL4445736)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)(C)c1nc(C)no1)=C2O)ccc3O |r,c:37,THB:10:9:17:4.5.6| Show InChI InChI=1S/C27H32N4O6/c1-13-28-24(37-30-13)25(2,3)29-23(34)16-11-27(35)18-10-15-6-7-17(32)21-19(15)26(27,22(36-21)20(16)33)8-9-31(18)12-14-4-5-14/h6-7,14,18,22,32-33,35H,4-5,8-12H2,1-3H3,(H,29,34)/t18-,22+,26+,27-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503607
(CHEMBL4452187)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)N1CCCC1)=C2O)ccc3O |r,c:32,THB:10:9:17:4.5.6| Show InChI InChI=1S/C25H30N2O5/c28-17-6-5-15-11-18-25(31)12-16(23(30)26-8-1-2-9-26)20(29)22-24(25,19(15)21(17)32-22)7-10-27(18)13-14-3-4-14/h5-6,14,18,22,28-29,31H,1-4,7-13H2/t18-,22+,24+,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503610
(CHEMBL4516674)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c(C)nc(N)nc21)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C23H26N4O3/c1-11-14-9-23(29)16-8-13-4-5-15(28)19-17(13)22(23,6-7-27(16)10-12-2-3-12)20(30-19)18(14)26-21(24)25-11/h4-5,12,16,20,28-29H,2-3,6-10H2,1H3,(H2,24,25,26)/t16-,20+,22+,23-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503609
(CHEMBL4543425)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)Nc1ccccn1)=C2O)ccc3O |r,c:34,THB:10:9:17:4.5.6| Show InChI InChI=1S/C26H27N3O5/c30-17-7-6-15-11-18-26(33)12-16(24(32)28-19-3-1-2-9-27-19)21(31)23-25(26,20(15)22(17)34-23)8-10-29(18)13-14-4-5-14/h1-3,6-7,9,14,18,23,30-31,33H,4-5,8,10-13H2,(H,27,28,32)/t18-,23+,25+,26-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 9.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM102406
(US8536192, I-135)Show SMILES COC(=O)C1(CC1)NC(=O)C1=C(O)[C@@H]2Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]24[C@@]5(O)C1)ccc3O |r,c:11,TLB:21:20:28:16.17.18| Show InChI InChI=1S/C26H30N2O7/c1-34-23(32)24(6-7-24)27-22(31)15-11-26(33)17-10-14-4-5-16(29)20-18(14)25(26,21(35-20)19(15)30)8-9-28(17)12-13-2-3-13/h4-5,13,17,21,29-30,33H,2-3,6-12H2,1H3,(H,27,31)/t17-,21+,25+,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503598
(CHEMBL4551066)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)CC)=C2O)ccc3O |r,c:28,THB:10:9:17:4.5.6| Show InChI InChI=1S/C23H27NO5/c1-2-15(25)14-10-23(28)17-9-13-5-6-16(26)20-18(13)22(23,21(29-20)19(14)27)7-8-24(17)11-12-3-4-12/h5-6,12,17,21,26-28H,2-4,7-11H2,1H3/t17-,21+,22+,23-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 9.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503605
(CHEMBL4457877)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)Nc1ccc(cc1)C#N)=C2O)ccc3O |r,c:36,THB:10:9:17:4.5.6| Show InChI InChI=1S/C28H27N3O5/c29-13-15-3-6-18(7-4-15)30-26(34)19-12-28(35)21-11-17-5-8-20(32)24-22(17)27(28,25(36-24)23(19)33)9-10-31(21)14-16-1-2-16/h3-8,16,21,25,32-33,35H,1-2,9-12,14H2,(H,30,34)/t21-,25+,27+,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503595
(CHEMBL4435773)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)(C)C(O)=O)=C2O)ccc3O |r,c:33,THB:10:9:17:4.5.6| Show InChI InChI=1S/C25H30N2O7/c1-23(2,22(31)32)26-21(30)14-10-25(33)16-9-13-5-6-15(28)19-17(13)24(25,20(34-19)18(14)29)7-8-27(16)11-12-3-4-12/h5-6,12,16,20,28-29,33H,3-4,7-11H2,1-2H3,(H,26,30)(H,31,32)/t16-,20+,24+,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503596
(CHEMBL4561876)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NCc1ccccc1)=C2O)ccc3O |r,c:35,THB:10:9:17:4.5.6| Show InChI InChI=1S/C28H30N2O5/c31-20-9-8-18-12-21-28(34)13-19(26(33)29-14-16-4-2-1-3-5-16)23(32)25-27(28,22(18)24(20)35-25)10-11-30(21)15-17-6-7-17/h1-5,8-9,17,21,25,31-32,34H,6-7,10-15H2,(H,29,33)/t21-,25+,27+,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503612
(CHEMBL4459343)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)(C)C(=O)OC)=C2O)ccc3O |r,c:34,THB:10:9:17:4.5.6| Show InChI InChI=1S/C26H32N2O7/c1-24(2,23(32)34-3)27-22(31)15-11-26(33)17-10-14-6-7-16(29)20-18(14)25(26,21(35-20)19(15)30)8-9-28(17)12-13-4-5-13/h6-7,13,17,21,29-30,33H,4-5,8-12H2,1-3H3,(H,27,31)/t17-,21+,25+,26-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503603
(CHEMBL4521187)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)N[C@H](C)CO)=C2O)ccc3O |r,c:31,THB:10:9:17:4.5.6| Show InChI InChI=1S/C24H30N2O6/c1-12(11-27)25-22(30)15-9-24(31)17-8-14-4-5-16(28)20-18(14)23(24,21(32-20)19(15)29)6-7-26(17)10-13-2-3-13/h4-5,12-13,17,21,27-29,31H,2-3,6-11H2,1H3,(H,25,30)/t12-,17-,21+,23+,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503606
(CHEMBL4462756)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2cc(ccc12)C(O)=O)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C27H26N2O5/c30-19-6-4-14-10-20-27(33)11-17-16-5-3-15(25(31)32)9-18(16)28-22(17)24-26(27,21(14)23(19)34-24)7-8-29(20)12-13-1-2-13/h3-6,9,13,20,24,28,30,33H,1-2,7-8,10-12H2,(H,31,32)/t20-,24+,26+,27-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503594
(CHEMBL4574150)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)Nc1ccc4cc[nH]c4c1)=C2O)ccc3O |r,c:38,THB:10:9:17:4.5.6| Show InChI InChI=1S/C29H29N3O5/c33-21-6-4-17-11-22-29(36)13-19(27(35)31-18-5-3-16-7-9-30-20(16)12-18)24(34)26-28(29,23(17)25(21)37-26)8-10-32(22)14-15-1-2-15/h3-7,9,12,15,22,26,30,33-34,36H,1-2,8,10-11,13-14H2,(H,31,35)/t22-,26+,28+,29-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503611
(CHEMBL4468216)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2c(Cl)c(ccc12)C(O)=O)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C27H25ClN2O5/c28-20-15(25(32)33)5-4-14-16-10-27(34)18-9-13-3-6-17(31)23-19(13)26(27,7-8-30(18)11-12-1-2-12)24(35-23)22(16)29-21(14)20/h3-6,12,18,24,29,31,34H,1-2,7-11H2,(H,32,33)/t18-,24+,26+,27-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503603
(CHEMBL4521187)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)N[C@H](C)CO)=C2O)ccc3O |r,c:31,THB:10:9:17:4.5.6| Show InChI InChI=1S/C24H30N2O6/c1-12(11-27)25-22(30)15-9-24(31)17-8-14-4-5-16(28)20-18(14)23(24,21(32-20)19(15)29)6-7-26(17)10-13-2-3-13/h4-5,12-13,17,21,27-29,31H,2-3,6-11H2,1H3,(H,25,30)/t12-,17-,21+,23+,24-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503599
(CHEMBL4439770)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c(C)n[nH]c21)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C22H25N3O3/c1-11-14-9-22(27)16-8-13-4-5-15(26)19-17(13)21(22,20(28-19)18(14)24-23-11)6-7-25(16)10-12-2-3-12/h4-5,12,16,20,26-27H,2-3,6-10H2,1H3,(H,23,24)/t16-,20+,21+,22-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50503597
(CHEMBL4534307)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(C)=O)=C2O)ccc3O |r,c:27,THB:10:9:17:4.5.6| Show InChI InChI=1S/C22H25NO5/c1-11(24)14-9-22(27)16-8-13-4-5-15(25)19-17(13)21(22,20(28-19)18(14)26)6-7-23(16)10-12-2-3-12/h4-5,12,16,20,25-27H,2-3,6-10H2,1H3/t16-,20+,21+,22-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503595
(CHEMBL4435773)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)(C)C(O)=O)=C2O)ccc3O |r,c:33,THB:10:9:17:4.5.6| Show InChI InChI=1S/C25H30N2O7/c1-23(2,22(31)32)26-21(30)14-10-25(33)16-9-13-5-6-15(28)19-17(13)24(25,20(34-19)18(14)29)7-8-27(16)11-12-3-4-12/h5-6,12,16,20,28-29,33H,3-4,7-11H2,1-2H3,(H,26,30)(H,31,32)/t16-,20+,24+,25-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50503602
(CHEMBL4472077)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC(C(=O)NC(C)(C)C(=O)NS(C)(=O)=O)=C2O)ccc3O |r,c:37,THB:10:9:17:4.5.6| Show InChI InChI=1S/C26H33N3O8S/c1-24(2,23(33)28-38(3,35)36)27-22(32)15-11-26(34)17-10-14-6-7-16(30)20-18(14)25(26,21(37-20)19(15)31)8-9-29(17)12-13-4-5-13/h6-7,13,17,21,30-31,34H,4-5,8-12H2,1-3H3,(H,27,32)(H,28,33)/t17-,21+,25+,26-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50278337
(CHEMBL470617 | Naltrexone methiodide)Show SMILES C[N+]1(CC2CC2)CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CCC4=O)ccc5O |r| Show InChI InChI=1S/C21H25NO4/c1-22(11-12-2-3-12)9-8-20-17-13-4-5-14(23)18(17)26-19(20)15(24)6-7-21(20,25)16(22)10-13/h4-5,12,16,19,25H,2-3,6-11H2,1H3/p+1/t16-,19+,20+,21-,22?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi Co., Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 29: 73-77 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.007
BindingDB Entry DOI: 10.7270/Q2H41VQS |
More data for this
Ligand-Target Pair | |
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