Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | Assay Description A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain... | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform C of Bromodomain-containing protein 4 (Short) (Homo sapiens (Human)) | BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM298346 (US10124009, Compound 1) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | Assay Description A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain... | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform C of Bromodomain-containing protein 4 (Short) (Homo sapiens (Human)) | BDBM298346 (US10124009, Compound 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM298347 (US10124009, Compound 2) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | Assay Description A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain... | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform C of Bromodomain-containing protein 4 (Short) (Homo sapiens (Human)) | BDBM298347 (US10124009, Compound 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform C of Bromodomain-containing protein 4 (Short) (Homo sapiens (Human)) | BDBM298351 (US10124009, Compound 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform C of Bromodomain-containing protein 4 (Short) (Homo sapiens (Human)) | BDBM298348 (US10124009, Compound 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM298349 (US10124009, Compound 4) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | Assay Description A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain... | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform C of Bromodomain-containing protein 4 (Short) (Homo sapiens (Human)) | BDBM298349 (US10124009, Compound 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM298350 (US10124009, Compound 5) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | Assay Description A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain... | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform C of Bromodomain-containing protein 4 (Short) (Homo sapiens (Human)) | BDBM298350 (US10124009, Compound 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM298351 (US10124009, Compound 7) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | Assay Description A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain... | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM298348 (US10124009, Compound 3) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | Assay Description A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain... | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | |||||||||||
More data for this Ligand-Target Pair |