Compile Data Set for Download or QSAR

Found 72 hits Enz. Inhib. hit(s) with all data for entry = 1013   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM303064 (US9598447, Ref No. FF) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(c1=O)P(O)(O)=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C26H36N3O4P/c1-16-9-17-11-18(10-16)13-21(12-17)28-19-5-4-6-20(28)15-22(14-19)29-24-8-3-2-7-23(24)27-25(26(29)30)34(31,32)33/h2-3,7-8,16-22H,4-6,9-15H2,1H3,(H2,31,32,33)/t16-,17-,18+,19-,20+,21+,22+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303069 (US9598447, Ref No. PP) Show SMILES CCOP(=O)(OCC)\C=C\c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@@H]2C[C@H]3C[C@H](C)C[C@H](C3)C2)c1=O |r,THB:28:27:19.20.26:22.24.23| Show InChI InChI=1S/C32H46N3O4P/c1-4-38-40(37,39-5-2)14-13-30-32(36)35(31-12-7-6-11-29(31)33-30)28-20-25-9-8-10-26(21-28)34(25)27-18-23-15-22(3)16-24(17-23)19-27/h6-7,11-14,22-28H,4-5,8-10,15-21H2,1-3H3/b14-13+/t22-,23-,24+,25-,26+,27+,28+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303069 (US9598447, Ref No. PP) Show SMILES CCOP(=O)(OCC)\C=C\c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@@H]2C[C@H]3C[C@H](C)C[C@H](C3)C2)c1=O |r,THB:28:27:19.20.26:22.24.23| Show InChI InChI=1S/C32H46N3O4P/c1-4-38-40(37,39-5-2)14-13-30-32(36)35(31-12-7-6-11-29(31)33-30)28-20-25-9-8-10-26(21-28)34(25)27-18-23-15-22(3)16-24(17-23)19-27/h6-7,11-14,22-28H,4-5,8-10,15-21H2,1-3H3/b14-13+/t22-,23-,24+,25-,26+,27+,28+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303068 (US9598447, Ref No. OO) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(NCCP(O)(O)=O)c1=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C28H41N4O4P/c1-18-11-19-13-20(12-18)15-23(14-19)31-21-5-4-6-22(31)17-24(16-21)32-26-8-3-2-7-25(26)30-27(28(32)33)29-9-10-37(34,35)36/h2-3,7-8,18-24H,4-6,9-17H2,1H3,(H,29,30)(H2,34,35,36)/t18-,19-,20+,21-,22+,23+,24+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303071 (US9598447, Ref No. TT) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(CCP(O)(O)=O)c1=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C28H40N3O4P/c1-18-11-19-13-20(12-18)15-23(14-19)30-21-5-4-6-22(30)17-24(16-21)31-27-8-3-2-7-25(27)29-26(28(31)32)9-10-36(33,34)35/h2-3,7-8,18-24H,4-6,9-17H2,1H3,(H2,33,34,35)/t18-,19-,20+,21-,22+,23+,24+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303070 (US9598447, Ref No. QQ) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(\C=C\P(O)(O)=O)c1=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C28H38N3O4P/c1-18-11-19-13-20(12-18)15-23(14-19)30-21-5-4-6-22(30)17-24(16-21)31-27-8-3-2-7-25(27)29-26(28(31)32)9-10-36(33,34)35/h2-3,7-10,18-24H,4-6,11-17H2,1H3,(H2,33,34,35)/b10-9+/t18-,19-,20+,21-,22+,23+,24+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303074 (US9598447, Ref No. XX) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(N2CCC(=CC2)P(C)(O)=O)c1=O |r,c:36,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C32H45N4O3P/c1-21-14-22-16-23(15-21)18-26(17-22)35-24-6-5-7-25(35)20-27(19-24)36-30-9-4-3-8-29(30)33-31(32(36)37)34-12-10-28(11-13-34)40(2,38)39/h3-4,8-10,21-27H,5-7,11-20H2,1-2H3,(H,38,39)/t21-,22-,23+,24-,25+,26+,27+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303065 (US9598447, Ref No. HH) Show SMILES OP(O)(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@@H]2C[C@H]3CCC[C@H](C3)C2)c1=O |r,THB:22:21:13.14.20:16.18.17| Show InChI InChI=1S/C25H34N3O4P/c29-25-24(33(30,31)32)26-22-9-1-2-10-23(22)28(25)21-14-18-7-4-8-19(15-21)27(18)20-12-16-5-3-6-17(11-16)13-20/h1-2,9-10,16-21H,3-8,11-15H2,(H2,30,31,32)/t16-,17+,18-,19+,20+,21+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303072 (US9598447, Ref No. VV) Show SMILES CC1(C)[C@@H]2CC1[C@H](CCN1[C@H]3CCC[C@@H]1C[C@@H](C3)n1c3ccccc3nc(c1=O)P(O)(O)=O)CC2 |r,THB:8:9:16.17.15:11.13.12| Show InChI InChI=1S/C27H38N3O4P/c1-27(2)18-11-10-17(22(27)14-18)12-13-29-19-6-5-7-20(29)16-21(15-19)30-24-9-4-3-8-23(24)28-25(26(30)31)35(32,33)34/h3-4,8-9,17-22H,5-7,10-16H2,1-2H3,(H2,32,33,34)/t17-,18-,19-,20+,21+,22?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303073 (US9598447, Ref No. WW) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(c1=O)P(O)(=O)OCOC(=O)c1ccccc1 |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C34H42N3O6P/c1-22-14-23-16-24(15-22)18-28(17-23)36-26-10-7-11-27(36)20-29(19-26)37-31-13-6-5-12-30(31)35-32(33(37)38)44(40,41)43-21-42-34(39)25-8-3-2-4-9-25/h2-6,8-9,12-13,22-24,26-29H,7,10-11,14-21H2,1H3,(H,40,41)/t22-,23-,24+,26-,27+,28+,29+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	12.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303067 (US9598447, Ref No. MM) Show SMILES OP(O)(=O)CCNc1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@@H]2C[C@H]3CCC[C@H](C3)C2)c1=O |r,THB:25:24:16.17.23:19.21.20| Show InChI InChI=1S/C27H39N4O4P/c32-27-26(28-11-12-36(33,34)35)29-24-9-1-2-10-25(24)31(27)23-16-20-7-4-8-21(17-23)30(20)22-14-18-5-3-6-19(13-18)15-22/h1-2,9-10,18-23H,3-8,11-17H2,(H,28,29)(H2,33,34,35)/t18-,19+,20-,21+,22+,23+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	24.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM303064 (US9598447, Ref No. FF) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(c1=O)P(O)(O)=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C26H36N3O4P/c1-16-9-17-11-18(10-16)13-21(12-17)28-19-5-4-6-20(28)15-22(14-19)29-24-8-3-2-7-23(24)27-25(26(29)30)34(31,32)33/h2-3,7-8,16-22H,4-6,9-15H2,1H3,(H2,31,32,33)/t16-,17-,18+,19-,20+,21+,22+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	28.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303063 (US9598447, Ref No. DD) Show SMILES OP(O)(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3C2CCCCCCC2)c1=O |r,THB:22:21:13.14.20:16.18.17| Show InChI InChI=1S/C24H34N3O4P/c28-24-23(32(29,30)31)25-21-13-6-7-14-22(21)27(24)20-15-18-11-8-12-19(16-20)26(18)17-9-4-2-1-3-5-10-17/h6-7,13-14,17-20H,1-5,8-12,15-16H2,(H2,29,30,31)/t18-,19+,20+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	29.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM303069 (US9598447, Ref No. PP) Show SMILES CCOP(=O)(OCC)\C=C\c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@@H]2C[C@H]3C[C@H](C)C[C@H](C3)C2)c1=O |r,THB:28:27:19.20.26:22.24.23| Show InChI InChI=1S/C32H46N3O4P/c1-4-38-40(37,39-5-2)14-13-30-32(36)35(31-12-7-6-11-29(31)33-30)28-20-25-9-8-10-26(21-28)34(25)27-18-23-15-22(3)16-24(17-23)19-27/h6-7,11-14,22-28H,4-5,8-10,15-21H2,1-3H3/b14-13+/t22-,23-,24+,25-,26+,27+,28+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	29.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303061 (US9598447, Ref No. AA) Show SMILES CCOP(=O)(OCC)c1nc2ccccc2n([C@@H]2C[C@@H]3CC[C@H](C2)N3C23CC4CC2CC(C3)C4)c1=O |r,TLB:28:27:32:29.30,THB:25:24:17.18.23:20.21,28:29:32:33.27.26,30:31:29.28:26| Show InChI InChI=1S/C28H38N3O4P/c1-3-34-36(33,35-4-2)26-27(32)30(25-8-6-5-7-24(25)29-26)23-14-21-9-10-22(15-23)31(21)28-16-18-11-19(17-28)13-20(28)12-18/h5-8,18-23H,3-4,9-17H2,1-2H3/t18?,19?,20?,21-,22+,23+,28?	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	31.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303073 (US9598447, Ref No. WW) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(c1=O)P(O)(=O)OCOC(=O)c1ccccc1 |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C34H42N3O6P/c1-22-14-23-16-24(15-22)18-28(17-23)36-26-10-7-11-27(36)20-29(19-26)37-31-13-6-5-12-30(31)35-32(33(37)38)44(40,41)43-21-42-34(39)25-8-3-2-4-9-25/h2-6,8-9,12-13,22-24,26-29H,7,10-11,14-21H2,1H3,(H,40,41)/t22-,23-,24+,26-,27+,28+,29+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	37.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303072 (US9598447, Ref No. VV) Show SMILES CC1(C)[C@@H]2CC1[C@H](CCN1[C@H]3CCC[C@@H]1C[C@@H](C3)n1c3ccccc3nc(c1=O)P(O)(O)=O)CC2 |r,THB:8:9:16.17.15:11.13.12| Show InChI InChI=1S/C27H38N3O4P/c1-27(2)18-11-10-17(22(27)14-18)12-13-29-19-6-5-7-20(29)16-21(15-19)30-24-9-4-3-8-23(24)28-25(26(30)31)35(32,33)34/h3-4,8-9,17-22H,5-7,10-16H2,1-2H3,(H2,32,33,34)/t17-,18-,19-,20+,21+,22?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	43.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303061 (US9598447, Ref No. AA) Show SMILES CCOP(=O)(OCC)c1nc2ccccc2n([C@@H]2C[C@@H]3CC[C@H](C2)N3C23CC4CC2CC(C3)C4)c1=O |r,TLB:28:27:32:29.30,THB:25:24:17.18.23:20.21,28:29:32:33.27.26,30:31:29.28:26| Show InChI InChI=1S/C28H38N3O4P/c1-3-34-36(33,35-4-2)26-27(32)30(25-8-6-5-7-24(25)29-26)23-14-21-9-10-22(15-23)31(21)28-16-18-11-19(17-28)13-20(28)12-18/h5-8,18-23H,3-4,9-17H2,1-2H3/t18?,19?,20?,21-,22+,23+,28?	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	48.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303062 (US9598447, Ref No. BB) Show SMILES OP(O)(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CC[C@H](C2)N3C23CC4CC2CC(C3)C4)c1=O |r,TLB:24:23:28:25.26,THB:21:20:13.14.19:16.17,24:25:28:29.23.22,26:27:25.24:22| Show InChI InChI=1S/C24H30N3O4P/c28-23-22(32(29,30)31)25-20-3-1-2-4-21(20)26(23)19-10-17-5-6-18(11-19)27(17)24-12-14-7-15(13-24)9-16(24)8-14/h1-4,14-19H,5-13H2,(H2,29,30,31)/t14?,15?,16?,17-,18+,19+,24?	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	58.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303071 (US9598447, Ref No. TT) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(CCP(O)(O)=O)c1=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C28H40N3O4P/c1-18-11-19-13-20(12-18)15-23(14-19)30-21-5-4-6-22(30)17-24(16-21)31-27-8-3-2-7-25(27)29-26(28(31)32)9-10-36(33,34)35/h2-3,7-8,18-24H,4-6,9-17H2,1H3,(H2,33,34,35)/t18-,19-,20+,21-,22+,23+,24+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM303071 (US9598447, Ref No. TT) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(CCP(O)(O)=O)c1=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C28H40N3O4P/c1-18-11-19-13-20(12-18)15-23(14-19)30-21-5-4-6-22(30)17-24(16-21)31-27-8-3-2-7-25(27)29-26(28(31)32)9-10-36(33,34)35/h2-3,7-8,18-24H,4-6,9-17H2,1H3,(H2,33,34,35)/t18-,19-,20+,21-,22+,23+,24+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303066 (US9598447, Ref No. KK) Show SMILES OP(O)(=O)NC(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3C2CCCCCCC2)c1=O |r,THB:25:24:16.17.23:19.21.20| Show InChI InChI=1S/C25H35N4O5P/c30-24(27-35(32,33)34)23-25(31)29(22-14-7-6-13-21(22)26-23)20-15-18-11-8-12-19(16-20)28(18)17-9-4-2-1-3-5-10-17/h6-7,13-14,17-20H,1-5,8-12,15-16H2,(H3,27,30,32,33,34)/t18-,19+,20+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303064 (US9598447, Ref No. FF) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(c1=O)P(O)(O)=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C26H36N3O4P/c1-16-9-17-11-18(10-16)13-21(12-17)28-19-5-4-6-20(28)15-22(14-19)29-24-8-3-2-7-23(24)27-25(26(29)30)34(31,32)33/h2-3,7-8,16-22H,4-6,9-15H2,1H3,(H2,31,32,33)/t16-,17-,18+,19-,20+,21+,22+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	267	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM303073 (US9598447, Ref No. WW) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(c1=O)P(O)(=O)OCOC(=O)c1ccccc1 |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C34H42N3O6P/c1-22-14-23-16-24(15-22)18-28(17-23)36-26-10-7-11-27(36)20-29(19-26)37-31-13-6-5-12-30(31)35-32(33(37)38)44(40,41)43-21-42-34(39)25-8-3-2-4-9-25/h2-6,8-9,12-13,22-24,26-29H,7,10-11,14-21H2,1H3,(H,40,41)/t22-,23-,24+,26-,27+,28+,29+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	396	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303070 (US9598447, Ref No. QQ) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(\C=C\P(O)(O)=O)c1=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C28H38N3O4P/c1-18-11-19-13-20(12-18)15-23(14-19)30-21-5-4-6-22(30)17-24(16-21)31-27-8-3-2-7-25(27)29-26(28(31)32)9-10-36(33,34)35/h2-3,7-10,18-24H,4-6,11-17H2,1H3,(H2,33,34,35)/b10-9+/t18-,19-,20+,21-,22+,23+,24+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	403	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM303061 (US9598447, Ref No. AA) Show SMILES CCOP(=O)(OCC)c1nc2ccccc2n([C@@H]2C[C@@H]3CC[C@H](C2)N3C23CC4CC2CC(C3)C4)c1=O |r,TLB:28:27:32:29.30,THB:25:24:17.18.23:20.21,28:29:32:33.27.26,30:31:29.28:26| Show InChI InChI=1S/C28H38N3O4P/c1-3-34-36(33,35-4-2)26-27(32)30(25-8-6-5-7-24(25)29-26)23-14-21-9-10-22(15-23)31(21)28-16-18-11-19(17-28)13-20(28)12-18/h5-8,18-23H,3-4,9-17H2,1-2H3/t18?,19?,20?,21-,22+,23+,28?	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	429	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM303070 (US9598447, Ref No. QQ) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(\C=C\P(O)(O)=O)c1=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C28H38N3O4P/c1-18-11-19-13-20(12-18)15-23(14-19)30-21-5-4-6-22(30)17-24(16-21)31-27-8-3-2-7-25(27)29-26(28(31)32)9-10-36(33,34)35/h2-3,7-10,18-24H,4-6,11-17H2,1H3,(H2,33,34,35)/b10-9+/t18-,19-,20+,21-,22+,23+,24+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	505	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM303062 (US9598447, Ref No. BB) Show SMILES OP(O)(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CC[C@H](C2)N3C23CC4CC2CC(C3)C4)c1=O |r,TLB:24:23:28:25.26,THB:21:20:13.14.19:16.17,24:25:28:29.23.22,26:27:25.24:22| Show InChI InChI=1S/C24H30N3O4P/c28-23-22(32(29,30)31)25-20-3-1-2-4-21(20)26(23)19-10-17-5-6-18(11-19)27(17)24-12-14-7-15(13-24)9-16(24)8-14/h1-4,14-19H,5-13H2,(H2,29,30,31)/t14?,15?,16?,17-,18+,19+,24?	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303063 (US9598447, Ref No. DD) Show SMILES OP(O)(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3C2CCCCCCC2)c1=O |r,THB:22:21:13.14.20:16.18.17| Show InChI InChI=1S/C24H34N3O4P/c28-24-23(32(29,30)31)25-21-13-6-7-14-22(21)27(24)20-15-18-11-8-12-19(16-20)26(18)17-9-4-2-1-3-5-10-17/h6-7,13-14,17-20H,1-5,8-12,15-16H2,(H2,29,30,31)/t18-,19+,20+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM303064 (US9598447, Ref No. FF) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(c1=O)P(O)(O)=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C26H36N3O4P/c1-16-9-17-11-18(10-16)13-21(12-17)28-19-5-4-6-20(28)15-22(14-19)29-24-8-3-2-7-23(24)27-25(26(29)30)34(31,32)33/h2-3,7-8,16-22H,4-6,9-15H2,1H3,(H2,31,32,33)/t16-,17-,18+,19-,20+,21+,22+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM303063 (US9598447, Ref No. DD) Show SMILES OP(O)(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3C2CCCCCCC2)c1=O |r,THB:22:21:13.14.20:16.18.17| Show InChI InChI=1S/C24H34N3O4P/c28-24-23(32(29,30)31)25-21-13-6-7-14-22(21)27(24)20-15-18-11-8-12-19(16-20)26(18)17-9-4-2-1-3-5-10-17/h6-7,13-14,17-20H,1-5,8-12,15-16H2,(H2,29,30,31)/t18-,19+,20+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303062 (US9598447, Ref No. BB) Show SMILES OP(O)(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CC[C@H](C2)N3C23CC4CC2CC(C3)C4)c1=O |r,TLB:24:23:28:25.26,THB:21:20:13.14.19:16.17,24:25:28:29.23.22,26:27:25.24:22| Show InChI InChI=1S/C24H30N3O4P/c28-23-22(32(29,30)31)25-20-3-1-2-4-21(20)26(23)19-10-17-5-6-18(11-19)27(17)24-12-14-7-15(13-24)9-16(24)8-14/h1-4,14-19H,5-13H2,(H2,29,30,31)/t14?,15?,16?,17-,18+,19+,24?	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.96E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM303069 (US9598447, Ref No. PP) Show SMILES CCOP(=O)(OCC)\C=C\c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@@H]2C[C@H]3C[C@H](C)C[C@H](C3)C2)c1=O |r,THB:28:27:19.20.26:22.24.23| Show InChI InChI=1S/C32H46N3O4P/c1-4-38-40(37,39-5-2)14-13-30-32(36)35(31-12-7-6-11-29(31)33-30)28-20-25-9-8-10-26(21-28)34(25)27-18-23-15-22(3)16-24(17-23)19-27/h6-7,11-14,22-28H,4-5,8-10,15-21H2,1-3H3/b14-13+/t22-,23-,24+,25-,26+,27+,28+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM303073 (US9598447, Ref No. WW) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(c1=O)P(O)(=O)OCOC(=O)c1ccccc1 |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C34H42N3O6P/c1-22-14-23-16-24(15-22)18-28(17-23)36-26-10-7-11-27(36)20-29(19-26)37-31-13-6-5-12-30(31)35-32(33(37)38)44(40,41)43-21-42-34(39)25-8-3-2-4-9-25/h2-6,8-9,12-13,22-24,26-29H,7,10-11,14-21H2,1H3,(H,40,41)/t22-,23-,24+,26-,27+,28+,29+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM303070 (US9598447, Ref No. QQ) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(\C=C\P(O)(O)=O)c1=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C28H38N3O4P/c1-18-11-19-13-20(12-18)15-23(14-19)30-21-5-4-6-22(30)17-24(16-21)31-27-8-3-2-7-25(27)29-26(28(31)32)9-10-36(33,34)35/h2-3,7-10,18-24H,4-6,11-17H2,1H3,(H2,33,34,35)/b10-9+/t18-,19-,20+,21-,22+,23+,24+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.59E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM303071 (US9598447, Ref No. TT) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(CCP(O)(O)=O)c1=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C28H40N3O4P/c1-18-11-19-13-20(12-18)15-23(14-19)30-21-5-4-6-22(30)17-24(16-21)31-27-8-3-2-7-25(27)29-26(28(31)32)9-10-36(33,34)35/h2-3,7-8,18-24H,4-6,9-17H2,1H3,(H2,33,34,35)/t18-,19-,20+,21-,22+,23+,24+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303066 (US9598447, Ref No. KK) Show SMILES OP(O)(=O)NC(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3C2CCCCCCC2)c1=O |r,THB:25:24:16.17.23:19.21.20| Show InChI InChI=1S/C25H35N4O5P/c30-24(27-35(32,33)34)23-25(31)29(22-14-7-6-13-21(22)26-23)20-15-18-11-8-12-19(16-20)28(18)17-9-4-2-1-3-5-10-17/h6-7,13-14,17-20H,1-5,8-12,15-16H2,(H3,27,30,32,33,34)/t18-,19+,20+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	7.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM303066 (US9598447, Ref No. KK) Show SMILES OP(O)(=O)NC(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3C2CCCCCCC2)c1=O |r,THB:25:24:16.17.23:19.21.20| Show InChI InChI=1S/C25H35N4O5P/c30-24(27-35(32,33)34)23-25(31)29(22-14-7-6-13-21(22)26-23)20-15-18-11-8-12-19(16-20)28(18)17-9-4-2-1-3-5-10-17/h6-7,13-14,17-20H,1-5,8-12,15-16H2,(H3,27,30,32,33,34)/t18-,19+,20+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM303072 (US9598447, Ref No. VV) Show SMILES CC1(C)[C@@H]2CC1[C@H](CCN1[C@H]3CCC[C@@H]1C[C@@H](C3)n1c3ccccc3nc(c1=O)P(O)(O)=O)CC2 |r,THB:8:9:16.17.15:11.13.12| Show InChI InChI=1S/C27H38N3O4P/c1-27(2)18-11-10-17(22(27)14-18)12-13-29-19-6-5-7-20(29)16-21(15-19)30-24-9-4-3-8-23(24)28-25(26(30)31)35(32,33)34/h3-4,8-9,17-22H,5-7,10-16H2,1-2H3,(H2,32,33,34)/t17-,18-,19-,20+,21+,22?/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM303066 (US9598447, Ref No. KK) Show SMILES OP(O)(=O)NC(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3C2CCCCCCC2)c1=O |r,THB:25:24:16.17.23:19.21.20| Show InChI InChI=1S/C25H35N4O5P/c30-24(27-35(32,33)34)23-25(31)29(22-14-7-6-13-21(22)26-23)20-15-18-11-8-12-19(16-20)28(18)17-9-4-2-1-3-5-10-17/h6-7,13-14,17-20H,1-5,8-12,15-16H2,(H3,27,30,32,33,34)/t18-,19+,20+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM303063 (US9598447, Ref No. DD) Show SMILES OP(O)(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3C2CCCCCCC2)c1=O |r,THB:22:21:13.14.20:16.18.17| Show InChI InChI=1S/C24H34N3O4P/c28-24-23(32(29,30)31)25-21-13-6-7-14-22(21)27(24)20-15-18-11-8-12-19(16-20)26(18)17-9-4-2-1-3-5-10-17/h6-7,13-14,17-20H,1-5,8-12,15-16H2,(H2,29,30,31)/t18-,19+,20+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM303061 (US9598447, Ref No. AA) Show SMILES CCOP(=O)(OCC)c1nc2ccccc2n([C@@H]2C[C@@H]3CC[C@H](C2)N3C23CC4CC2CC(C3)C4)c1=O |r,TLB:28:27:32:29.30,THB:25:24:17.18.23:20.21,28:29:32:33.27.26,30:31:29.28:26| Show InChI InChI=1S/C28H38N3O4P/c1-3-34-36(33,35-4-2)26-27(32)30(25-8-6-5-7-24(25)29-26)23-14-21-9-10-22(15-23)31(21)28-16-18-11-19(17-28)13-20(28)12-18/h5-8,18-23H,3-4,9-17H2,1-2H3/t18?,19?,20?,21-,22+,23+,28?	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM303062 (US9598447, Ref No. BB) Show SMILES OP(O)(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CC[C@H](C2)N3C23CC4CC2CC(C3)C4)c1=O |r,TLB:24:23:28:25.26,THB:21:20:13.14.19:16.17,24:25:28:29.23.22,26:27:25.24:22| Show InChI InChI=1S/C24H30N3O4P/c28-23-22(32(29,30)31)25-20-3-1-2-4-21(20)26(23)19-10-17-5-6-18(11-19)27(17)24-12-14-7-15(13-24)9-16(24)8-14/h1-4,14-19H,5-13H2,(H2,29,30,31)/t14?,15?,16?,17-,18+,19+,24?	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM303072 (US9598447, Ref No. VV) Show SMILES CC1(C)[C@@H]2CC1[C@H](CCN1[C@H]3CCC[C@@H]1C[C@@H](C3)n1c3ccccc3nc(c1=O)P(O)(O)=O)CC2 |r,THB:8:9:16.17.15:11.13.12| Show InChI InChI=1S/C27H38N3O4P/c1-27(2)18-11-10-17(22(27)14-18)12-13-29-19-6-5-7-20(29)16-21(15-19)30-24-9-4-3-8-23(24)28-25(26(30)31)35(32,33)34/h3-4,8-9,17-22H,5-7,10-16H2,1-2H3,(H2,32,33,34)/t17-,18-,19-,20+,21+,22?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303071 (US9598447, Ref No. TT) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(CCP(O)(O)=O)c1=O |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C28H40N3O4P/c1-18-11-19-13-20(12-18)15-23(14-19)30-21-5-4-6-22(30)17-24(16-21)31-27-8-3-2-7-25(27)29-26(28(31)32)9-10-36(33,34)35/h2-3,7-8,18-24H,4-6,9-17H2,1H3,(H2,33,34,35)/t18-,19-,20+,21-,22+,23+,24+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303072 (US9598447, Ref No. VV) Show SMILES CC1(C)[C@@H]2CC1[C@H](CCN1[C@H]3CCC[C@@H]1C[C@@H](C3)n1c3ccccc3nc(c1=O)P(O)(O)=O)CC2 |r,THB:8:9:16.17.15:11.13.12| Show InChI InChI=1S/C27H38N3O4P/c1-27(2)18-11-10-17(22(27)14-18)12-13-29-19-6-5-7-20(29)16-21(15-19)30-24-9-4-3-8-23(24)28-25(26(30)31)35(32,33)34/h3-4,8-9,17-22H,5-7,10-16H2,1-2H3,(H2,32,33,34)/t17-,18-,19-,20+,21+,22?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303072 (US9598447, Ref No. VV) Show SMILES CC1(C)[C@@H]2CC1[C@H](CCN1[C@H]3CCC[C@@H]1C[C@@H](C3)n1c3ccccc3nc(c1=O)P(O)(O)=O)CC2 |r,THB:8:9:16.17.15:11.13.12| Show InChI InChI=1S/C27H38N3O4P/c1-27(2)18-11-10-17(22(27)14-18)12-13-29-19-6-5-7-20(29)16-21(15-19)30-24-9-4-3-8-23(24)28-25(26(30)31)35(32,33)34/h3-4,8-9,17-22H,5-7,10-16H2,1-2H3,(H2,32,33,34)/t17-,18-,19-,20+,21+,22?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM303073 (US9598447, Ref No. WW) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(c1=O)P(O)(=O)OCOC(=O)c1ccccc1 |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C34H42N3O6P/c1-22-14-23-16-24(15-22)18-28(17-23)36-26-10-7-11-27(36)20-29(19-26)37-31-13-6-5-12-30(31)35-32(33(37)38)44(40,41)43-21-42-34(39)25-8-3-2-4-9-25/h2-6,8-9,12-13,22-24,26-29H,7,10-11,14-21H2,1H3,(H,40,41)/t22-,23-,24+,26-,27+,28+,29+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM303073 (US9598447, Ref No. WW) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(c1=O)P(O)(=O)OCOC(=O)c1ccccc1 |r,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C34H42N3O6P/c1-22-14-23-16-24(15-22)18-28(17-23)36-26-10-7-11-27(36)20-29(19-26)37-31-13-6-5-12-30(31)35-32(33(37)38)44(40,41)43-21-42-34(39)25-8-3-2-4-9-25/h2-6,8-9,12-13,22-24,26-29H,7,10-11,14-21H2,1H3,(H,40,41)/t22-,23-,24+,26-,27+,28+,29+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM303074 (US9598447, Ref No. XX) Show SMILES C[C@H]1C[C@H]2C[C@@H](C1)C[C@@H](C2)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(N2CCC(=CC2)P(C)(O)=O)c1=O |r,c:36,THB:8:10:17.18.16:12.14.13| Show InChI InChI=1S/C32H45N4O3P/c1-21-14-22-16-23(15-21)18-26(17-22)35-24-6-5-7-25(35)20-27(19-24)36-30-9-4-3-8-29(30)33-31(32(36)37)34-12-10-28(11-13-34)40(2,38)39/h3-4,8-10,21-27H,5-7,11-20H2,1-2H3,(H,38,39)/t21-,22-,23+,24-,25+,26+,27+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	26.6	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...				US Patent US9598447 (2017) BindingDB Entry DOI: 10.7270/Q2P27168
					More data for this Ligand-Target Pair

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