Compile Data Set for Download or QSAR

Found 26 hits Enz. Inhib. hit(s) with all data for entry = 1594   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332027 ((E)-N'-(3-methoxy-2- hydroxybenzal)-2-{N-{2-[N- (n...) Show SMILES COc1cccc(\C=N\NC(=O)CN(C)CCN(C)Cc2cccc3ccccc23)c1O Show InChI InChI=1S/C25H30N4O3/c1-28(17-21-11-6-9-19-8-4-5-12-22(19)21)14-15-29(2)18-24(30)27-26-16-20-10-7-13-23(32-3)25(20)31/h4-13,16,31H,14-15,17-18H2,1-3H3,(H,27,30)/b26-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332042 ((E)-N'-(2,3- dihydroxybenzal)-2-{N-{2- [N-(3-metho...) Show SMILES COc1cccc(CN(C)CCN(C)CC(=O)N\N=C\c2cccc(O)c2O)c1 Show InChI InChI=1S/C21H28N4O4/c1-24(14-16-6-4-8-18(12-16)29-3)10-11-25(2)15-20(27)23-22-13-17-7-5-9-19(26)21(17)28/h4-9,12-13,26,28H,10-11,14-15H2,1-3H3,(H,23,27)/b22-13+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	820	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332029 ((E)-N'-(3-ethoxy-2- hydroxybenzal)-2-{N-{2- [N-(na...) Show SMILES CCOc1cccc(\C=N\NC(=O)CN(C)CCN(C)Cc2cccc3ccccc23)c1O Show InChI InChI=1S/C26H32N4O3/c1-4-33-24-14-8-11-21(26(24)32)17-27-28-25(31)19-30(3)16-15-29(2)18-22-12-7-10-20-9-5-6-13-23(20)22/h5-14,17,32H,4,15-16,18-19H2,1-3H3,(H,28,31)/b27-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332030 ((E)-N'-[(2- hydroxynaphthalen-1- yl)methylene]-2-{...) Show SMILES CN(CCN(C)Cc1cccc2ccccc12)CC(=O)N\N=C\c1c(O)ccc2ccccc12 Show InChI InChI=1S/C28H30N4O2/c1-31(19-23-11-7-10-21-8-3-5-12-24(21)23)16-17-32(2)20-28(34)30-29-18-26-25-13-6-4-9-22(25)14-15-27(26)33/h3-15,18,33H,16-17,19-20H2,1-2H3,(H,30,34)/b29-18+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	830	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332031 ((E)-N'-(4-N,N- diethylamino-2- hydroxybenzal)-2-{N...) Show SMILES CCN(CC)c1ccc(\C=N\NC(=O)CN(C)CCN(C)Cc2cccc3ccccc23)c(O)c1 Show InChI InChI=1S/C28H37N5O2/c1-5-33(6-2)25-15-14-23(27(34)18-25)19-29-30-28(35)21-32(4)17-16-31(3)20-24-12-9-11-22-10-7-8-13-26(22)24/h7-15,18-19,34H,5-6,16-17,20-21H2,1-4H3,(H,30,35)/b29-19+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	780	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332032 ((E)-N'-(3,5-di-tert-butyl-2- hydroxybenzal)-2-{N-{...) Show SMILES CN(CCN(C)Cc1cccc(c1)C(F)(F)F)CC(=O)N\N=C\c1cc(cc(c1O)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C29H41F3N4O2/c1-27(2,3)23-15-21(26(38)24(16-23)28(4,5)6)17-33-34-25(37)19-36(8)13-12-35(7)18-20-10-9-11-22(14-20)29(30,31)32/h9-11,14-17,38H,12-13,18-19H2,1-8H3,(H,34,37)/b33-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.23E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332033 ((E)-N'-(4-N,N- diethylamino-2- hydroxybenzal)-2-{N...) Show SMILES CCN(CC)c1ccc(\C=N\NC(=O)CN(C)CCN(C)Cc2cccc(c2)C(F)(F)F)c(O)c1 Show InChI InChI=1S/C25H34F3N5O2/c1-5-33(6-2)22-11-10-20(23(34)15-22)16-29-30-24(35)18-32(4)13-12-31(3)17-19-8-7-9-21(14-19)25(26,27)28/h7-11,14-16,34H,5-6,12-13,17-18H2,1-4H3,(H,30,35)/b29-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332034 ((E)-N'-(2,3- dihydroxybenzal)-2-{N-{2- [N-(3- trif...) Show SMILES CN(CCN(C)Cc1cccc(c1)C(F)(F)F)CC(=O)N\N=C\c1cccc(O)c1O Show InChI InChI=1S/C21H25F3N4O3/c1-27(13-15-5-3-7-17(11-15)21(22,23)24)9-10-28(2)14-19(30)26-25-12-16-6-4-8-18(29)20(16)31/h3-8,11-12,29,31H,9-10,13-14H2,1-2H3,(H,26,30)/b25-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332035 ((E)-N'-[(3-ethoxy-2- hydroxybenzal)methylene]- 2-{...) Show SMILES CCOc1cccc(\C=N\NC(=O)CN(C)CCN(C)Cc2ccc(cc2)C(C)C)c1O Show InChI InChI=1S/C25H36N4O3/c1-6-32-23-9-7-8-22(25(23)31)16-26-27-24(30)18-29(5)15-14-28(4)17-20-10-12-21(13-11-20)19(2)3/h7-13,16,19,31H,6,14-15,17-18H2,1-5H3,(H,27,30)/b26-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332036 ((E)-N'-[(2- hydroxynaphthalen-1- yl)methylene]-2-{...) Show SMILES CC(C)c1ccc(CN(C)CCN(C)CC(=O)N\N=C\c2c(O)ccc3ccccc23)cc1 Show InChI InChI=1S/C27H34N4O2/c1-20(2)22-11-9-21(10-12-22)18-30(3)15-16-31(4)19-27(33)29-28-17-25-24-8-6-5-7-23(24)13-14-26(25)32/h5-14,17,20,32H,15-16,18-19H2,1-4H3,(H,29,33)/b28-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332037 ((E)-N'-(3,5-di-tert-butyl-2- hydroxybenzal)-2-{N-{...) Show SMILES CC(C)c1ccc(CN(C)CCN(C)CC(=O)N\N=C\c2cc(cc(c2O)C(C)(C)C)C(C)(C)C)cc1 Show InChI InChI=1S/C31H48N4O2/c1-22(2)24-13-11-23(12-14-24)20-34(9)15-16-35(10)21-28(36)33-32-19-25-17-26(30(3,4)5)18-27(29(25)37)31(6,7)8/h11-14,17-19,22,37H,15-16,20-21H2,1-10H3,(H,33,36)/b32-19+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332038 ((E)-N'-(2,3- dihydroxybenzal)-2-{N-{2- [N-(4-isopr...) Show SMILES CC(C)c1ccc(CN(C)CCN(C)CC(=O)N\N=C\c2cccc(O)c2O)cc1 Show InChI InChI=1S/C23H32N4O3/c1-17(2)19-10-8-18(9-11-19)15-26(3)12-13-27(4)16-22(29)25-24-14-20-6-5-7-21(28)23(20)30/h5-11,14,17,28,30H,12-13,15-16H2,1-4H3,(H,25,29)/b24-14+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	560	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332039 ((E)-N'-(3-bromo-6- hydroxybenzal)-2-{N-{2- [N-(4-i...) Show SMILES CC(C)c1ccc(CN(C)CCN(C)CC(=O)N\N=C\c2cc(Br)ccc2O)cc1 Show InChI InChI=1S/C23H31BrN4O2/c1-17(2)19-7-5-18(6-8-19)15-27(3)11-12-28(4)16-23(30)26-25-14-20-13-21(24)9-10-22(20)29/h5-10,13-14,17,29H,11-12,15-16H2,1-4H3,(H,26,30)/b25-14+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.28E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332040 ((E)-N'-(3,5-di-tert-butyl-2- hydroxybenzal)-2-{N-{...) Show SMILES COc1cccc(CN(C)CCN(C)CC(=O)N\N=C\c2cc(cc(c2O)C(C)(C)C)C(C)(C)C)c1 Show InChI InChI=1S/C29H44N4O3/c1-28(2,3)23-16-22(27(35)25(17-23)29(4,5)6)18-30-31-26(34)20-33(8)14-13-32(7)19-21-11-10-12-24(15-21)36-9/h10-12,15-18,35H,13-14,19-20H2,1-9H3,(H,31,34)/b30-18+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.77E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332041 ((E)-N'-(4-N,N- diethylamino-2- hydroxybenzal)-2-{N...) Show SMILES CCN(CC)c1ccc(\C=N\NC(=O)CN(C)CCN(C)Cc2cccc(OC)c2)c(O)c1 Show InChI InChI=1S/C25H37N5O3/c1-6-30(7-2)22-12-11-21(24(31)16-22)17-26-27-25(32)19-29(4)14-13-28(3)18-20-9-8-10-23(15-20)33-5/h8-12,15-17,31H,6-7,13-14,18-19H2,1-5H3,(H,27,32)/b26-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	760	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332043 ((E)-N'-(3-bromo-6- hydroxybenzal)-2-{N-{2- [N-(3-m...) Show SMILES COc1cccc(CN(C)CCN(C)CC(=O)N\N=C\c2cc(Br)ccc2O)c1 Show InChI InChI=1S/C21H27BrN4O3/c1-25(14-16-5-4-6-19(11-16)29-3)9-10-26(2)15-21(28)24-23-13-17-12-18(22)7-8-20(17)27/h4-8,11-13,27H,9-10,14-15H2,1-3H3,(H,24,28)/b23-13+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.19E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332044 ((E)-N'-[(2- hydroxynaphthalen-1- yl)methylene]-2-{...) Show SMILES CN(CCN(C)Cc1ccc(cc1)C#N)CC(=O)N\N=C\c1c(O)ccc2ccccc12 Show InChI InChI=1S/C25H27N5O2/c1-29(17-20-9-7-19(15-26)8-10-20)13-14-30(2)18-25(32)28-27-16-23-22-6-4-3-5-21(22)11-12-24(23)31/h3-12,16,31H,13-14,17-18H2,1-2H3,(H,28,32)/b27-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	980	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332045 ((E)-N'-(3,5-di-tert-butyl-2- hydroxybenzal)-2-{N-{...) Show SMILES CN(CCN(C)Cc1ccc(cc1)C#N)CC(=O)N\N=C\c1cc(cc(c1O)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C29H41N5O2/c1-28(2,3)24-15-23(27(36)25(16-24)29(4,5)6)18-31-32-26(35)20-34(8)14-13-33(7)19-22-11-9-21(17-30)10-12-22/h9-12,15-16,18,36H,13-14,19-20H2,1-8H3,(H,32,35)/b31-18+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.75E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332046 ((E)-N'-(3-methoxy-2- hydroxybenzal)-2-{N-{2-[N- (4...) Show SMILES COc1cccc(\C=N\NC(=O)CN(C)CCN(C)Cc2ccc(cc2)C#N)c1O Show InChI InChI=1S/C22H27N5O3/c1-26(15-18-9-7-17(13-23)8-10-18)11-12-27(2)16-21(28)25-24-14-19-5-4-6-20(30-3)22(19)29/h4-10,14,29H,11-12,15-16H2,1-3H3,(H,25,28)/b24-14+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8.42E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332047 ((E)-N'-(3-ethoxy-2- hydroxybenzal)-2-{N-{2- [N-(4-...) Show SMILES CCOc1cccc(\C=N\NC(=O)CN(C)CCN(C)Cc2ccc(cc2)C#N)c1O Show InChI InChI=1S/C23H29N5O3/c1-4-31-21-7-5-6-20(23(21)30)15-25-26-22(29)17-28(3)13-12-27(2)16-19-10-8-18(14-24)9-11-19/h5-11,15,30H,4,12-13,16-17H2,1-3H3,(H,26,29)/b25-15+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.77E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332048 ((E)-N'-(4-N,N-diethylamino- 2-hydroxybenzal)-2-{N-...) Show SMILES CCN(CC)c1ccc(\C=N\NC(=O)CN(C)CCN(C)Cc2ccc(cc2)C#N)c(O)c1 Show InChI InChI=1S/C25H34N6O2/c1-5-31(6-2)23-12-11-22(24(32)15-23)17-27-28-25(33)19-30(4)14-13-29(3)18-21-9-7-20(16-26)8-10-21/h7-12,15,17,32H,5-6,13-14,18-19H2,1-4H3,(H,28,33)/b27-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332049 ((E)-N'-(3-methoxy-2- hydroxybenzal)-2-{N-{2-[N- (4...) Show SMILES COc1cccc(\C=N\NC(=O)CN(C)CCN(C)Cc2ccc(cc2)C(C)(C)C)c1O Show InChI InChI=1S/C25H36N4O3/c1-25(2,3)21-12-10-19(11-13-21)17-28(4)14-15-29(5)18-23(30)27-26-16-20-8-7-9-22(32-6)24(20)31/h7-13,16,31H,14-15,17-18H2,1-6H3,(H,27,30)/b26-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.76E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332050 ((E)-N'-(3-ethoxy-2- hydroxybenzal)-2-{N-{2-[N- (4-...) Show SMILES CCOc1cccc(\C=N\NC(=O)CN(C)CCN(C)Cc2ccc(cc2)C(C)(C)C)c1O Show InChI InChI=1S/C26H38N4O3/c1-7-33-23-10-8-9-21(25(23)32)17-27-28-24(31)19-30(6)16-15-29(5)18-20-11-13-22(14-12-20)26(2,3)4/h8-14,17,32H,7,15-16,18-19H2,1-6H3,(H,28,31)/b27-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332051 ((E)-N'-(4-N,N-diethylamino- 2-hydroxybenzal)-2-{N-...) Show SMILES CCN(CC)c1ccc(\C=N\NC(=O)CN(C)CCCN(C)Cc2ccc(cc2)C(C)(C)C)c(O)c1 Show InChI InChI=1S/C29H45N5O2/c1-8-34(9-2)26-16-13-24(27(35)19-26)20-30-31-28(36)22-33(7)18-10-17-32(6)21-23-11-14-25(15-12-23)29(3,4)5/h11-16,19-20,35H,8-10,17-18,21-22H2,1-7H3,(H,31,36)/b30-20+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	4.14E+4	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332028 ((E)-N'-(3,5-di-tert-butyl-2- hydroxybenzal)-2-{N-{...) Show SMILES CN(CCN(C)Cc1cccc2ccccc12)CC(=O)N\N=C\c1cc(cc(c1O)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C32H44N4O2/c1-31(2,3)26-18-25(30(38)28(19-26)32(4,5)6)20-33-34-29(37)22-36(8)17-16-35(7)21-24-14-11-13-23-12-9-10-15-27(23)24/h9-15,18-20,38H,16-17,21-22H2,1-8H3,(H,34,37)/b33-20+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair