Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50300203 ((S)-6-(1-hydroxy-3-methylbutyl)-7-methoxy-2H-chrom...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426702 (CHEMBL2326514) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426700 (CHEMBL2326516) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426695 (CHEMBL2326521) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426703 (CHEMBL2326513) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426694 (CHEMBL2326522) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426705 (CHEMBL2326511) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM12342 (2H-chromen-2-one | CHEMBL6466 | Coumarin) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426701 (CHEMBL2326515) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426699 (CHEMBL2326517) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426696 (CHEMBL2326520) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426698 (CHEMBL2326518) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426697 (CHEMBL2326519) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426711 (CHEMBL2326506) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426710 (CHEMBL2326507) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426709 (CHEMBL2326508) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426708 (CHEMBL2326509 | Naphtho[1,2-E][1,2]Oxathiine 3,3-D...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426707 (CHEMBL2326510) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426704 (CHEMBL2326512) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426706 (CHEMBL2321923) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair |