Compile Data Set for Download or QSAR

Found 80 hits Enz. Inhib. hit(s) with all data for assayid = 4 entry = 7001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164889 (US10166239, Ex. 3-3 | US11406644, Example 3-3 | US...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(ccc34)-c3ccc(nc3)P(C)(C)=O)cc2OC)cc1 Show InChI InChI=1S/C30H31N4O4P/c1-36-24-10-5-20(6-11-24)19-38-27-13-7-21(15-28(27)37-2)18-34-26-12-8-22(16-25(26)33-30(34)31)23-9-14-29(32-17-23)39(3,4)35/h5-17H,18-19H2,1-4H3,(H2,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164887 (US10166239, Ex. 3-2-2 | US11406644, Example 3-2-2 ...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(ccc34)-c3ccncc3)cc2OC)cc1 Show InChI InChI=1S/C28H26N4O3/c1-33-23-7-3-19(4-8-23)18-35-26-10-5-20(15-27(26)34-2)17-32-25-9-6-22(16-24(25)31-28(32)29)21-11-13-30-14-12-21/h3-16H,17-18H2,1-2H3,(H2,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164937 (US10166239, Ex. 3-37-5 | US11406644, Example 3-37-...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3ccncc3)cc2OC)cn1 Show InChI InChI=1S/C26H24N6O3/c1-33-23-11-17(3-5-22(23)35-16-18-4-6-24(34-2)29-13-18)15-32-25-21(31-26(32)27)12-20(14-30-25)19-7-9-28-10-8-19/h3-14H,15-16H2,1-2H3,(H2,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 | US11406644, Example 3-15 | ...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3cnn(C)c3)cc2OC)cc1 Show InChI InChI=1S/C26H26N6O3/c1-31-15-20(13-29-31)19-11-22-25(28-12-19)32(26(27)30-22)14-18-6-9-23(24(10-18)34-3)35-16-17-4-7-21(33-2)8-5-17/h4-13,15H,14,16H2,1-3H3,(H2,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164885 (US10166239, Ex. 3-1 | US11406644, Example 3-1 | US...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(ccc34)-c3cnn(C)c3)cc2OC)cc1 Show InChI InChI=1S/C27H27N5O3/c1-31-16-21(14-29-31)20-7-10-24-23(13-20)30-27(28)32(24)15-19-6-11-25(26(12-19)34-3)35-17-18-4-8-22(33-2)9-5-18/h4-14,16H,15,17H2,1-3H3,(H2,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164911 (US10166239, Ex. 3-19 | US11406644, Example 3-19 | ...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)-c3cnn(c3)C3CCNCC3)cc2OC)cn1 Show InChI InChI=1S/C29H31N7O3/c1-37-27-11-20(3-5-26(27)39-18-21-4-6-28(38-2)31-13-21)16-35-19-33-25-12-22(14-32-29(25)35)23-15-34-36(17-23)24-7-9-30-10-8-24/h3-6,11-15,17,19,24,30H,7-10,16,18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164891 (US10166239, Ex. 3-5 | US11406644, Example 3-5 | US...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(ccc34)-c3cnn(c3)C3CCNCC3)cc2OC)cn1 Show InChI InChI=1S/C30H32N6O3/c1-37-29-13-21(3-7-28(29)39-19-22-4-8-30(38-2)32-15-22)17-35-20-33-26-14-23(5-6-27(26)35)24-16-34-36(18-24)25-9-11-31-12-10-25/h3-8,13-16,18,20,25,31H,9-12,17,19H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164902 (US10166239, Ex. 3-16 | US11406644, Example 3-16 | ...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3ccc(nc3)P(C)(C)=O)cc2OC)cc1 Show InChI InChI=1S/C29H30N5O4P/c1-36-23-9-5-19(6-10-23)18-38-25-11-7-20(13-26(25)37-2)17-34-28-24(33-29(34)30)14-22(16-32-28)21-8-12-27(31-15-21)39(3,4)35/h5-16H,17-18H2,1-4H3,(H2,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164927 (US10166239, Ex. 3-35-1 | US11406644, Example 3-35-...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3cnn(C)c3)cc2OC)cn1 Show InChI InChI=1S/C25H25N7O3/c1-31-14-19(12-29-31)18-9-20-24(28-11-18)32(25(26)30-20)13-16-4-6-21(22(8-16)33-2)35-15-17-5-7-23(34-3)27-10-17/h4-12,14H,13,15H2,1-3H3,(H2,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164912 (US10166239, Ex. 3-20 | US11406644, Example 3-20 | ...) Show SMILES COc1cc(Cn2cnc3cc(cnc23)-c2cnn(c2)C2CCNCC2)ccc1OCc1ccc(C)nc1 Show InChI InChI=1S/C29H31N7O2/c1-20-3-4-22(13-31-20)18-38-27-6-5-21(11-28(27)37-2)16-35-19-33-26-12-23(14-32-29(26)35)24-15-34-36(17-24)25-7-9-30-10-8-25/h3-6,11-15,17,19,25,30H,7-10,16,18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164917 (US10166239, Ex. 3-25 | US11406644, Example 3-25 | ...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)-n3cc(nn3)C3CCCNC3)cc2OC)cn1 Show InChI InChI=1S/C28H30N8O3/c1-37-26-10-19(5-7-25(26)39-17-20-6-8-27(38-2)30-12-20)15-35-18-32-23-11-22(14-31-28(23)35)36-16-24(33-34-36)21-4-3-9-29-13-21/h5-8,10-12,14,16,18,21,29H,3-4,9,13,15,17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164930 (US10166239, Ex. 3-35-4 | US11406644, Example 3-35-...) Show SMILES COc1cc(Cn2c(N)nc3cc(cnc23)-c2cnn(C)c2)ccc1OCc1ccc(nc1)C1CC1 Show InChI InChI=1S/C27H27N7O2/c1-33-15-21(13-31-33)20-10-23-26(30-12-20)34(27(28)32-23)14-17-4-8-24(25(9-17)35-2)36-16-18-3-7-22(29-11-18)19-5-6-19/h3-4,7-13,15,19H,5-6,14,16H2,1-2H3,(H2,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164888 (US10166239, Ex. 3-2-3 | US11406644, Example 3-2-3 ...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(ccc34)-c3cnn(CCN4CCOCC4)c3)cc2OC)cc1 Show InChI InChI=1S/C32H36N6O4/c1-39-27-7-3-23(4-8-27)22-42-30-10-5-24(17-31(30)40-2)20-38-29-9-6-25(18-28(29)35-32(38)33)26-19-34-37(21-26)12-11-36-13-15-41-16-14-36/h3-10,17-19,21H,11-16,20,22H2,1-2H3,(H2,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164886 (US10166239, Ex. 3-2-1 | US11406644, Example 3-2-1 ...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(ccc34)-c3cncnc3)cc2OC)cc1 Show InChI InChI=1S/C27H25N5O3/c1-33-22-7-3-18(4-8-22)16-35-25-10-5-19(11-26(25)34-2)15-32-24-9-6-20(12-23(24)31-27(32)28)21-13-29-17-30-14-21/h3-14,17H,15-16H2,1-2H3,(H2,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164943 (US10166239, Ex. 3-40-3 | US11406644, Example 3-40-...) Show SMILES COc1cc(Cn2c(N)nc3cc(cnc23)-c2cnn(C)c2)ccc1OCc1ccc(nc1)C(C)C Show InChI InChI=1S/C27H29N7O2/c1-17(2)22-7-5-19(11-29-22)16-36-24-8-6-18(9-25(24)35-4)14-34-26-23(32-27(34)28)10-20(12-30-26)21-13-31-33(3)15-21/h5-13,15,17H,14,16H2,1-4H3,(H2,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164928 (US10166239, Ex. 3-35-2 | US11406644, Example 3-35-...) Show SMILES COc1cc(Cn2c(N)nc3cc(cnc23)-c2cnn(C)c2)ccc1OCc1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C25H22F3N7O2/c1-34-13-18(11-32-34)17-8-19-23(31-10-17)35(24(29)33-19)12-15-3-5-20(21(7-15)36-2)37-14-16-4-6-22(30-9-16)25(26,27)28/h3-11,13H,12,14H2,1-2H3,(H2,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164936 (US10166239, Ex. 3-37-4 | US11406644, Example 3-37-...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3c(C)nn(C)c3C)cc2OC)cn1 Show InChI InChI=1S/C27H29N7O3/c1-16-25(17(2)33(3)32-16)20-11-21-26(30-13-20)34(27(28)31-21)14-18-6-8-22(23(10-18)35-4)37-15-19-7-9-24(36-5)29-12-19/h6-13H,14-15H2,1-5H3,(H2,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164904 (US10166239, Ex. 3-18-1 | US11406644, Example 3-18-...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)N3CCC(CC3)C(C)(C)N)cc2OC)cn1 Show InChI InChI=1S/C29H36N6O3/c1-29(2,30)22-9-11-34(12-10-22)23-14-24-28(32-16-23)35(19-33-24)17-20-5-7-25(26(13-20)36-3)38-18-21-6-8-27(37-4)31-15-21/h5-8,13-16,19,22H,9-12,17-18,30H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164929 (US10166239, Ex. 3-35-3 | US11406644, Example 3-35-...) Show SMILES COc1cc(Cn2c(N)nc3cc(cnc23)-c2cnn(C)c2)ccc1OCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C26H23F3N6O2/c1-34-14-19(12-32-34)18-10-21-24(31-11-18)35(25(30)33-21)13-17-5-8-22(23(9-17)36-2)37-15-16-3-6-20(7-4-16)26(27,28)29/h3-12,14H,13,15H2,1-2H3,(H2,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164931 (US10166239, Ex. 3-35-5 | US11406644, Example 3-35-...) Show SMILES COc1cc(Cn2c(N)nc3cc(cnc23)-c2cnn(C)c2)ccc1OCc1csc(C)n1 Show InChI InChI=1S/C23H23N7O2S/c1-14-27-18(13-33-14)12-32-20-5-4-15(6-21(20)31-3)10-30-22-19(28-23(30)24)7-16(8-25-22)17-9-26-29(2)11-17/h4-9,11,13H,10,12H2,1-3H3,(H2,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164934 (US10166239, Ex. 3-37-2 | US11406644, Example 3-37-...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3ccn(C)n3)cc2OC)cn1 Show InChI InChI=1S/C25H25N7O3/c1-31-9-8-19(30-31)18-11-20-24(28-13-18)32(25(26)29-20)14-16-4-6-21(22(10-16)33-2)35-15-17-5-7-23(34-3)27-12-17/h4-13H,14-15H2,1-3H3,(H2,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164939 (US10166239, Ex. 3-38 | US11406644, Example 3-38 | ...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3ccccn3)cc2OC)cn1 Show InChI InChI=1S/C26H24N6O3/c1-33-23-11-17(6-8-22(23)35-16-18-7-9-24(34-2)29-13-18)15-32-25-21(31-26(32)27)12-19(14-30-25)20-5-3-4-10-28-20/h3-14H,15-16H2,1-2H3,(H2,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164938 (US10166239, Ex. 3-37-6 | US11406644, Example 3-37-...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3cccnc3)cc2OC)cn1 Show InChI InChI=1S/C26H24N6O3/c1-33-23-10-17(5-7-22(23)35-16-18-6-8-24(34-2)29-12-18)15-32-25-21(31-26(32)27)11-20(14-30-25)19-4-3-9-28-13-19/h3-14H,15-16H2,1-2H3,(H2,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164892 (US10166239, Ex. 3-6 | US11406644, Example 3-6 | US...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(ccc34)-n3cc(nn3)C3CCCNC3)cc2OC)cn1 Show InChI InChI=1S/C29H31N7O3/c1-37-28-12-20(5-9-27(28)39-18-21-6-10-29(38-2)31-14-21)16-35-19-32-24-13-23(7-8-26(24)35)36-17-25(33-34-36)22-4-3-11-30-15-22/h5-10,12-14,17,19,22,30H,3-4,11,15-16,18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164932 (US10166239, Ex. 3-36 | US11406644, Example 3-36 | ...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3ccccc3)cc2OC)cn1 Show InChI InChI=1S/C27H25N5O3/c1-33-24-12-18(8-10-23(24)35-17-19-9-11-25(34-2)29-14-19)16-32-26-22(31-27(32)28)13-21(15-30-26)20-6-4-3-5-7-20/h3-15H,16-17H2,1-2H3,(H2,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164945 (US10166239, Ex. 3-40-5 | US11406644, Example 3-40-...) Show SMILES COc1cc(Cn2c(N)nc3cc(cnc23)-c2cnn(C)c2)ccc1OCc1csc(n1)C(F)(F)F Show InChI InChI=1S/C23H20F3N7O2S/c1-32-10-15(8-29-32)14-6-17-20(28-7-14)33(22(27)31-17)9-13-3-4-18(19(5-13)34-2)35-11-16-12-36-21(30-16)23(24,25)26/h3-8,10,12H,9,11H2,1-2H3,(H2,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164913 (US10166239, Ex. 3-21 | US11406644, Example 3-21 | ...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)-c3noc(n3)C3CCNCC3)cc2OC)cn1 Show InChI InChI=1S/C28H29N7O4/c1-36-24-11-18(3-5-23(24)38-16-19-4-6-25(37-2)30-13-19)15-35-17-32-22-12-21(14-31-27(22)35)26-33-28(39-34-26)20-7-9-29-10-8-20/h3-6,11-14,17,20,29H,7-10,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164916 (US10166239, Ex. 3-24 | US11406644, Example 3-24 | ...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)-n3cc(nn3)C(C)(C)N)cc2OC)cn1 Show InChI InChI=1S/C26H28N8O3/c1-26(2,27)23-14-34(32-31-23)19-10-20-25(29-12-19)33(16-30-20)13-17-5-7-21(22(9-17)35-3)37-15-18-6-8-24(36-4)28-11-18/h5-12,14,16H,13,15,27H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164908 (US10166239, Ex. 3-18-5 | US11406644, Example 3-18-...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)N3CC4(C3)CCNCC4)cc2OC)cn1 Show InChI InChI=1S/C28H32N6O3/c1-35-25-11-20(3-5-24(25)37-16-21-4-6-26(36-2)30-13-21)15-33-19-32-23-12-22(14-31-27(23)33)34-17-28(18-34)7-9-29-10-8-28/h3-6,11-14,19,29H,7-10,15-18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164941 (US10166239, Ex. 3-40-1 | US11406644, Example 3-40-...) Show SMILES COc1cc(Cn2c(N)nc3cc(cnc23)-c2cnn(C)c2)ccc1OCc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C26H23F3N6O3/c1-34-14-19(12-32-34)18-10-21-24(31-11-18)35(25(30)33-21)13-17-5-8-22(23(9-17)36-2)37-15-16-3-6-20(7-4-16)38-26(27,28)29/h3-12,14H,13,15H2,1-2H3,(H2,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164905 (US10166239, Ex. 3-18-2 | US11406644, Example 3-18-...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)N3CCOCC3)cc2OC)cn1 Show InChI InChI=1S/C25H27N5O4/c1-31-23-11-18(3-5-22(23)34-16-19-4-6-24(32-2)26-13-19)15-30-17-28-21-12-20(14-27-25(21)30)29-7-9-33-10-8-29/h3-6,11-14,17H,7-10,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164933 (US10166239, Ex. 3-37-1 | US11406644, Example 3-37-...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3ccc(F)cc3)cc2OC)cn1 Show InChI InChI=1S/C27H24FN5O3/c1-34-24-11-17(3-9-23(24)36-16-18-4-10-25(35-2)30-13-18)15-33-26-22(32-27(33)29)12-20(14-31-26)19-5-7-21(28)8-6-19/h3-14H,15-16H2,1-2H3,(H2,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164944 (US10166239, Ex. 3-40-4 | US11406644, Example 3-40-...) Show SMILES COc1cc(Cn2c(N)nc3cc(cnc23)-c2cnn(C)c2)ccc1OCc1ccc(CC(F)(F)F)cc1 Show InChI InChI=1S/C27H25F3N6O2/c1-35-15-21(13-33-35)20-10-22-25(32-12-20)36(26(31)34-22)14-19-7-8-23(24(9-19)37-2)38-16-18-5-3-17(4-6-18)11-27(28,29)30/h3-10,12-13,15H,11,14,16H2,1-2H3,(H2,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164935 (US10166239, Ex. 3-37-3 | US11406644, Example 3-37-...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3cncnc3)cc2OC)cn1 Show InChI InChI=1S/C25H23N7O3/c1-33-22-7-16(3-5-21(22)35-14-17-4-6-23(34-2)29-9-17)13-32-24-20(31-25(32)26)8-18(12-30-24)19-10-27-15-28-11-19/h3-12,15H,13-14H2,1-2H3,(H2,26,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164903 (US10166239, Ex. 3-28 | US11274108, Example 1-254 |...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)N3CCN(C)CC3)cc2OC)cn1 Show InChI InChI=1S/C26H30N6O3/c1-30-8-10-31(11-9-30)21-13-22-26(28-15-21)32(18-29-22)16-19-4-6-23(24(12-19)33-2)35-17-20-5-7-25(34-3)27-14-20/h4-7,12-15,18H,8-11,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164909 (US10166239, Ex. 3-18-6 | US11406644, Example 3-18-...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)N3CCC(N)CC3)cc2OC)cn1 Show InChI InChI=1S/C26H30N6O3/c1-33-24-11-18(3-5-23(24)35-16-19-4-6-25(34-2)28-13-19)15-32-17-30-22-12-21(14-29-26(22)32)31-9-7-20(27)8-10-31/h3-6,11-14,17,20H,7-10,15-16,27H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164897 (US10166239, Ex. 3-11 | US11406644, Example 3-11 | ...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(ccc34)N3CC4(C3)CCNCC4)cc2OC)cn1 Show InChI InChI=1S/C29H33N5O3/c1-35-27-13-21(3-7-26(27)37-17-22-4-8-28(36-2)31-15-22)16-33-20-32-24-14-23(5-6-25(24)33)34-18-29(19-34)9-11-30-12-10-29/h3-8,13-15,20,30H,9-12,16-19H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164915 (US10166239, Ex. 3-23 | US11406644, Example 3-23 | ...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)-c3nnc(o3)C3CCNCC3)cc2OC)cn1 Show InChI InChI=1S/C28H29N7O4/c1-36-24-11-18(3-5-23(24)38-16-19-4-6-25(37-2)30-13-19)15-35-17-32-22-12-21(14-31-26(22)35)28-34-33-27(39-28)20-7-9-29-10-8-20/h3-6,11-14,17,20,29H,7-10,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164896 (US10166239, Ex. 3-10 | US11406644, Example 3-10 | ...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(ccc34)N3CCC(CC3)C(C)(C)N)cc2OC)cn1 Show InChI InChI=1S/C30H37N5O3/c1-30(2,31)23-11-13-34(14-12-23)24-7-8-26-25(16-24)33-20-35(26)18-21-5-9-27(28(15-21)36-3)38-19-22-6-10-29(37-4)32-17-22/h5-10,15-17,20,23H,11-14,18-19,31H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164947 (US10166239, Ex. 3-42 | US11406644, Example 3-42 | ...) Show SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)C#CCCO)cc2OC)cn1 Show InChI InChI=1S/C25H25N5O4/c1-32-22-12-18(6-8-21(22)34-16-19-7-9-23(33-2)27-14-19)15-30-24-20(29-25(30)26)11-17(13-28-24)5-3-4-10-31/h6-9,11-14,31H,4,10,15-16H2,1-2H3,(H2,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164914 (US10166239, Ex. 3-22 | US11406644, Example 3-22 | ...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(ccc34)-c3noc(n3)C3CCNCC3)cc2OC)cn1 Show InChI InChI=1S/C29H30N6O4/c1-36-26-13-19(3-7-25(26)38-17-20-4-8-27(37-2)31-15-20)16-35-18-32-23-14-22(5-6-24(23)35)28-33-29(39-34-28)21-9-11-30-12-10-21/h3-8,13-15,18,21,30H,9-12,16-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164922 (US10166239, Ex. 3-30 | US11406644, Example 3-30 | ...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)C3=CC4(C)CN3CCC4)cc2OC)cn1 |t:24| Show InChI InChI=1S/C29H31N5O3/c1-29-9-4-10-33(18-29)24(13-29)22-12-23-28(31-15-22)34(19-32-23)16-20-5-7-25(26(11-20)35-2)37-17-21-6-8-27(36-3)30-14-21/h5-8,11-15,19H,4,9-10,16-18H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164903 (US10166239, Ex. 3-28 | US11274108, Example 1-254 |...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)N3CCN(C)CC3)cc2OC)cn1 Show InChI InChI=1S/C26H30N6O3/c1-30-8-10-31(11-9-30)21-13-22-26(28-15-21)32(18-29-22)16-19-4-6-23(24(12-19)33-2)35-17-20-5-7-25(34-3)27-14-20/h4-7,12-15,18H,8-11,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164906 (US10166239, Ex. 3-18-3 | US11406644, Example 3-18-...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)N3CCN(CC3)C3CC3)cc2OC)cn1 Show InChI InChI=1S/C28H32N6O3/c1-35-26-13-20(3-7-25(26)37-18-21-4-8-27(36-2)29-15-21)17-34-19-31-24-14-23(16-30-28(24)34)33-11-9-32(10-12-33)22-5-6-22/h3-4,7-8,13-16,19,22H,5-6,9-12,17-18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164942 (US10166239, Ex. 3-40-2 | US11406644, Example 3-40-...) Show SMILES COc1cc(Cn2c(N)nc3cc(cnc23)-c2cnn(C)c2)ccc1OCc1ccc(SC(F)(F)F)cc1 Show InChI InChI=1S/C26H23F3N6O2S/c1-34-14-19(12-32-34)18-10-21-24(31-11-18)35(25(30)33-21)13-17-5-8-22(23(9-17)36-2)37-15-16-3-6-20(7-4-16)38-26(27,28)29/h3-12,14H,13,15H2,1-2H3,(H2,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164956 (US10166239, Ex. 3-49-6a | US11406644, Example 3-49...) Show SMILES COc1cc(ccc1OCc1ccc(cc1)C(F)(F)F)[C@H](C)n1c(N)nc2cc(cnc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C27H25F3N6O2/c1-16(36-25-22(34-26(36)31)10-19(12-32-25)20-13-33-35(2)14-20)18-6-9-23(24(11-18)37-3)38-15-17-4-7-21(8-5-17)27(28,29)30/h4-14,16H,15H2,1-3H3,(H2,31,34)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164962 (US10166239, Ex. 3-53 | US11406644, Example 3-53 | ...) Show SMILES COc1cc(ccc1OCc1ccc(nc1)C(F)(F)F)C(C)n1c(N)nc2cc(cnc12)-c1cnn(C)c1 Show InChI InChI=1S/C26H24F3N7O2/c1-15(36-24-20(34-25(36)30)8-18(11-32-24)19-12-33-35(2)13-19)17-5-6-21(22(9-17)37-3)38-14-16-4-7-23(31-10-16)26(27,28)29/h4-13,15H,14H2,1-3H3,(H2,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164965 (US10166239, Ex. 3-56 | US11406644, Example 3-56 | ...) Show SMILES COc1cc(Cn2cnc3cc(cnc23)C#CCCO)ccc1OCc1ccc(nc1)C(F)F Show InChI InChI=1S/C25H22F2N4O3/c1-33-23-11-18(6-8-22(23)34-15-19-5-7-20(24(26)27)28-13-19)14-31-16-30-21-10-17(4-2-3-9-32)12-29-25(21)31/h5-8,10-13,16,24,32H,3,9,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164895 (US10166239, Ex. 3-9 | US11406644, Example 3-9 | US...) Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(ccc34)C3CCOCC3)cc2OC)cn1 Show InChI InChI=1S/C27H29N3O4/c1-31-26-13-19(3-7-25(26)34-17-20-4-8-27(32-2)28-15-20)16-30-18-29-23-14-22(5-6-24(23)30)21-9-11-33-12-10-21/h3-8,13-15,18,21H,9-12,16-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164940 (US10166239, Ex. 3-39 | US11406644, Example 3-39 | ...) Show SMILES COc1cc(Cn2c(N)nc3cc(cnc23)-c2cnn(C)c2)ccc1OCc1ccc(cc1)C(F)(F)C(F)(F)F Show InChI InChI=1S/C27H23F5N6O2/c1-37-14-19(12-35-37)18-10-21-24(34-11-18)38(25(33)36-21)13-17-5-8-22(23(9-17)39-2)40-15-16-3-6-20(7-4-16)26(28,29)27(30,31)32/h3-12,14H,13,15H2,1-2H3,(H2,33,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
					More data for this Ligand-Target Pair

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