Compile Data Set for Download or QSAR

Found 6 hits of kd data for polymerid = 3592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50425824 (CHEMBL2312289) Show SMILES NC(=O)[C@@H]1CCCc2c1[nH]c1ccc(Cl)cc21 |r| Show InChI InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17)/t9-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
Lilly Biotechnology Center San Diego Curated by ChEMBL					Assay Description Binding affinity to C-terminally His-tagged SIRT1 catalytic domain (241 to 516 amino acid residues plus EGHHHHHH) (unknown origin) expressed in bacul...				J Med Chem 56: 963-9 (2013) Article DOI: 10.1021/jm301431y BindingDB Entry DOI: 10.7270/Q2B56M22
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50228364 (3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1 Show InChI InChI=1S/C26H29N5O4S/c1-33-22-12-17(13-23(34-2)24(22)35-3)25(32)28-20-7-5-4-6-19(20)21-15-31-18(16-36-26(31)29-21)14-30-10-8-27-9-11-30/h4-7,12-13,15-16,27H,8-11,14H2,1-3H3,(H,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a
Sirtris Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to SIRT1				J Med Chem 52: 1275-83 (2010) Article DOI: 10.1021/jm8012954 BindingDB Entry DOI: 10.7270/Q2ZC82V5
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50228364 (3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1 Show InChI InChI=1S/C26H29N5O4S/c1-33-22-12-17(13-23(34-2)24(22)35-3)25(32)28-20-7-5-4-6-19(20)21-15-31-18(16-36-26(31)29-21)14-30-10-8-27-9-11-30/h4-7,12-13,15-16,27H,8-11,14H2,1-3H3,(H,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a
Sirtris Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity to human SIRT1 by isothermal titration calorimetry				Nature 450: 712-716 (2007) Article DOI: 10.1038/nature06261 BindingDB Entry DOI: 10.7270/Q2765G67
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50576690 (CHEMBL4873772) Show SMILES O=C(NCCOCCOCCOCCNC(=O)c1cccc(c1)-c1cccnc1)c1cccc(c1)-c1cccnc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to chip-immobilized recombinant human SIRT1 measured after 300 secs by surface plasmon resonance method				Citation and Details Article DOI: 10.1016/j.bmc.2021.116328 BindingDB Entry DOI: 10.7270/Q23F4TGR
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50576701 (CHEMBL4867959) Show SMILES O=C(NCCCCCCNC(=O)c1cccc(c1)-c1cccnc1)c1cccc(c1)-c1cccnc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.18E+5	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to chip-immobilized recombinant human SIRT1 measured after 300 secs by surface plasmon resonance method				Citation and Details Article DOI: 10.1016/j.bmc.2021.116328 BindingDB Entry DOI: 10.7270/Q23F4TGR
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50576689 (CHEMBL4872893) Show SMILES COc1cc(CC(=O)NCCCCCCNC(=O)c2cccc(c2)-c2cccnc2)cc(OC)c1OC Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.39E+5	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to chip-immobilized recombinant human SIRT1 measured after 300 secs by surface plasmon resonance method				Citation and Details Article DOI: 10.1016/j.bmc.2021.116328 BindingDB Entry DOI: 10.7270/Q23F4TGR
					More data for this Ligand-Target Pair