BindingDB PrimarySearch

Found 10 hits of ki data for polymerid = 50001953,50003309,50003551
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human))	BDBM50183409 (CHEMBL3822531) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Competitive inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using increasing AFC substr...				Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-S-isoprenylcysteine O-methyltransferase (Rattus norvegicus)	BDBM50034278 (2-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienyls...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biological Research Curated by ChEMBL					Assay Description Ability to inhibit prenylated protein methyltransferase (PPMTase) in cell free systems				J Med Chem 38: 1267-72 (1995) BindingDB Entry DOI: 10.7270/Q2N015KK
Institute for Biological Research Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human))	BDBM50183409 (CHEMBL3822531) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Non-competitive inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes with increasing [14C]-S...				Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-S-isoprenylcysteine O-methyltransferase (Saccharomyces cerevisiae)	BDBM50174225 (((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylsul...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibitory concentration against isoprenyl-cysteine carboxyl methyltransferase				Bioorg Med Chem Lett 15: 5080-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.075 BindingDB Entry DOI: 10.7270/Q2028SBB
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-S-isoprenylcysteine O-methyltransferase (Rattus norvegicus)	BDBM50034280 (2-Chloro-5-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biological Research Curated by ChEMBL					Assay Description Ability to inhibit prenylated protein methyltransferase (PPMTase) in cell free systems				J Med Chem 38: 1267-72 (1995) BindingDB Entry DOI: 10.7270/Q2N015KK
Institute for Biological Research Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-S-isoprenylcysteine O-methyltransferase (Rattus norvegicus)	BDBM50034277 (CHEMBL23289 \| Thioacetic acid S-((2E,6E)-3,7,11-tr...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem	PubMed	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biological Research Curated by ChEMBL					Assay Description Ability to inhibit prenylated protein methyltransferase (PPMTase) in cell free systems				J Med Chem 38: 1267-72 (1995) BindingDB Entry DOI: 10.7270/Q2N015KK
Institute for Biological Research Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-S-isoprenylcysteine O-methyltransferase (Saccharomyces cerevisiae)	BDBM50174226 (2-acetamido-3-[(2E,6E,10E)-3,7,11,15-tetramethylhe...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibitory concentration against isoprenyl-cysteine carboxyl methyltransferase				Bioorg Med Chem Lett 15: 5080-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.075 BindingDB Entry DOI: 10.7270/Q2028SBB
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-S-isoprenylcysteine O-methyltransferase (Rattus norvegicus)	BDBM50034276 (2-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienyl-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biological Research Curated by ChEMBL					Assay Description Ability to inhibit prenylated protein methyltransferase (PPMTase) in cell free systems				J Med Chem 38: 1267-72 (1995) BindingDB Entry DOI: 10.7270/Q2N015KK
Institute for Biological Research Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-S-isoprenylcysteine O-methyltransferase (Saccharomyces cerevisiae)	BDBM50174224 ((R)-2-Acetylamino-3-[(2Z,6E)-7,11-dimethyl-3-(3-me...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	1.71E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibitory concentration against isoprenyl-cysteine carboxyl methyltransferase				Bioorg Med Chem Lett 15: 5080-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.075 BindingDB Entry DOI: 10.7270/Q2028SBB
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-S-isoprenylcysteine O-methyltransferase (Rattus norvegicus)	BDBM50034279 (5-Amino-2-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.28E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biological Research Curated by ChEMBL					Assay Description Ability to inhibit prenylated protein methyltransferase (PPMTase) in cell free systems				J Med Chem 38: 1267-72 (1995) BindingDB Entry DOI: 10.7270/Q2N015KK
Institute for Biological Research Curated by ChEMBL					More data for this Ligand-Target Pair