Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50564233 (CHEMBL4792854) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama Curated by ChEMBL | Assay Description Competitive inhibition of human lysosome alpha-galactosidase by Lineweaver-Burk plot analysis | Bioorg Med Chem 18: 3790-4 (2010) Article DOI: 10.1016/j.bmc.2010.04.048 BindingDB Entry DOI: 10.7270/Q2XK8FQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50564237 (CHEMBL4793095) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50234559 (CHEMBL4081664) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cheng-Kung University Curated by ChEMBL | Assay Description Non-competitive inhibition of recombinant human alpha GAL-A using varying levels of 4-methylumbelliferyl alpha-D-galactopyranoside substrate at pH 7 ... | Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50290908 (CHEMBL4160428) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Yang-Ming University Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant alpha-galactosidase A using 4-MU-alpha-d-galactopyranoside as substrate by Lineweaver-Burk plot method | Eur J Med Chem 144: 626-634 (2018) Article DOI: 10.1016/j.ejmech.2017.12.036 BindingDB Entry DOI: 10.7270/Q2736TG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50564249 (CHEMBL4789325) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Non-competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50564236 (CHEMBL4782789) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50234559 (CHEMBL4081664) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cheng-Kung University Curated by ChEMBL | Assay Description Non-competitive inhibition of recombinant human alpha GAL-A using varying levels of 4-methylumbelliferyl alpha-D-galactopyranoside substrate at pH 4.... | Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM18351 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB PubMed | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hamburg Curated by ChEMBL | Assay Description Compound tested for inhibition of alpha-galactosidase from Aspergillus niger | Bioorg Med Chem Lett 14: 73-5 (2003) BindingDB Entry DOI: 10.7270/Q2JM2925 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50564235 (CHEMBL4793871) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50564251 (CHEMBL4781544) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Non-competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50287006 (Azepane-3,4,5,6-tetraol | CHEMBL13922) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article | 6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of alpha-galactosidase from green coffee beans. | Bioorg Med Chem Lett 6: 1117-1122 (1996) Article DOI: 10.1016/0960-894X(96)00183-7 BindingDB Entry DOI: 10.7270/Q2M32VQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50456585 (CHEMBL4218664) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50137351 (2-(R)-Amino-3-(3,4,5,6-tetrahydroxy-tetrahydro-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hamburg Curated by ChEMBL | Assay Description Compound tested for inhibition of alpha-galactosidase from Aspergillus niger | Bioorg Med Chem Lett 14: 73-5 (2003) BindingDB Entry DOI: 10.7270/Q2JM2925 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50137350 (2-Amino-3-(3,4,5,6-tetrahydroxy-tetrahydro-pyran-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hamburg Curated by ChEMBL | Assay Description Compound tested for inhibition of alpha-galactosidase from Aspergillus niger | Bioorg Med Chem Lett 14: 73-5 (2003) BindingDB Entry DOI: 10.7270/Q2JM2925 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50350758 (CHEMBL1818433) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Graz University of Technology Curated by ChEMBL | Assay Description Inhibition of human recombinant lysosomal alpha-galactosidase using 2,4-dinitrophenyl-alpha-D-galactopyranoside as substrate preincubated up to 5 min... | Bioorg Med Chem Lett 26: 1438-42 (2016) Article DOI: 10.1016/j.bmcl.2016.01.059 BindingDB Entry DOI: 10.7270/Q2HQ41SR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50150471 (CHEMBL3770764) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Graz University of Technology Curated by ChEMBL | Assay Description Inhibition of human recombinant lysosomal alpha-galactosidase using 2,4-dinitrophenyl-alpha-D-galactopyranoside as substrate preincubated up to 5 min... | Bioorg Med Chem Lett 26: 1438-42 (2016) Article DOI: 10.1016/j.bmcl.2016.01.059 BindingDB Entry DOI: 10.7270/Q2HQ41SR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50150472 (CHEMBL3770736) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Graz University of Technology Curated by ChEMBL | Assay Description Inhibition of human recombinant lysosomal alpha-galactosidase using 2,4-dinitrophenyl-alpha-D-galactopyranoside as substrate preincubated up to 5 min... | Bioorg Med Chem Lett 26: 1438-42 (2016) Article DOI: 10.1016/j.bmcl.2016.01.059 BindingDB Entry DOI: 10.7270/Q2HQ41SR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50150470 (CHEMBL3771185) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Graz University of Technology Curated by ChEMBL | Assay Description Inhibition of human recombinant lysosomal alpha-galactosidase using 2,4-dinitrophenyl-alpha-D-galactopyranoside as substrate preincubated up to 5 min... | Bioorg Med Chem Lett 26: 1438-42 (2016) Article DOI: 10.1016/j.bmcl.2016.01.059 BindingDB Entry DOI: 10.7270/Q2HQ41SR | |||||||||||
More data for this Ligand-Target Pair |