Compile Data Set for Download or QSAR

Found 101 hits Enz. Inhib. hit(s) with Target = 'Alpha-galactosidase A'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113762 (1-Deoxygalactonojirimycin (DGJ) | 2-(hydroxymethyl...) Show SMILES OCC1NCC(O)C(O)C1O Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	0.780	n/a	n/a	n/a	n/a	7.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113758 (DGJ-pMe SPhT) Show SMILES CSc1ccc(NC(=S)N2C[C@H](O)[C@@H](O)[C@@H](O)[C@H]2CO)cc1 |r| Show InChI InChI=1S/C14H20N2O4S2/c1-22-9-4-2-8(3-5-9)15-14(21)16-6-11(18)13(20)12(19)10(16)7-17/h2-5,10-13,17-20H,6-7H2,1H3,(H,15,21)/t10-,11+,12+,13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113762 (1-Deoxygalactonojirimycin (DGJ) | 2-(hydroxymethyl...) Show SMILES OCC1NCC(O)C(O)C1O Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	5.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113758 (DGJ-pMe SPhT) Show SMILES CSc1ccc(NC(=S)N2C[C@H](O)[C@@H](O)[C@@H](O)[C@H]2CO)cc1 |r| Show InChI InChI=1S/C14H20N2O4S2/c1-22-9-4-2-8(3-5-9)15-14(21)16-6-11(18)13(20)12(19)10(16)7-17/h2-5,10-13,17-20H,6-7H2,1H3,(H,15,21)/t10-,11+,12+,13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	5.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50163440 ((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluorescence a...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113757 (DGJ-pMe OPhT) Show SMILES COc1ccc(NC(=S)N2C[C@H](O)[C@@H](O)[C@@H](O)[C@H]2CO)cc1 |r| Show InChI InChI=1S/C14H20N2O5S/c1-21-9-4-2-8(3-5-9)15-14(22)16-6-11(18)13(20)12(19)10(16)7-17/h2-5,10-13,17-20H,6-7H2,1H3,(H,15,22)/t10-,11+,12+,13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	7.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50163440 ((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 4.6 after 15 mins by fluorescence...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113759 (DGJ-pF PhT) Show SMILES OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)CN1C(=S)Nc1ccc(F)cc1 |r| Show InChI InChI=1S/C13H17FN2O4S/c14-7-1-3-8(4-2-7)15-13(21)16-5-10(18)12(20)11(19)9(16)6-17/h1-4,9-12,17-20H,5-6H2,(H,15,21)/t9-,10+,11+,12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	7.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50099009 ((3S,4S,5R)-2-Aminomethyl-5-hydroxymethyl-pyrrolidi...) Show SMILES NC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O Show InChI InChI=1S/C6H14N2O3/c7-1-3-5(10)6(11)4(2-9)8-3/h3-6,8-11H,1-2,7H2/t3-,4-,5?,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	7.0	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...				Eur J Med Chem 123: 14-20 (2016) Article DOI: 10.1016/j.ejmech.2016.07.025 BindingDB Entry DOI: 10.7270/Q2RB76KN
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50163440 ((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of human lysosome alpha-galactosidase assessed as p-nitrophenol release by spectrometric analysis				Bioorg Med Chem 18: 3790-4 (2010) Article DOI: 10.1016/j.bmc.2010.04.048 BindingDB Entry DOI: 10.7270/Q2XK8FQP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50163440 ((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory concentration against human alpha-galactosidase				J Med Chem 48: 2036-44 (2005) Article DOI: 10.1021/jm0495881 BindingDB Entry DOI: 10.7270/Q2DF6S0M
					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113757 (DGJ-pMe OPhT) Show SMILES COc1ccc(NC(=S)N2C[C@H](O)[C@@H](O)[C@@H](O)[C@H]2CO)cc1 |r| Show InChI InChI=1S/C14H20N2O5S/c1-21-9-4-2-8(3-5-9)15-14(22)16-6-11(18)13(20)12(19)10(16)7-17/h2-5,10-13,17-20H,6-7H2,1H3,(H,15,22)/t10-,11+,12+,13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	5.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113759 (DGJ-pF PhT) Show SMILES OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)CN1C(=S)Nc1ccc(F)cc1 |r| Show InChI InChI=1S/C13H17FN2O4S/c14-7-1-3-8(4-2-7)15-13(21)16-5-10(18)12(20)11(19)9(16)6-17/h1-4,9-12,17-20H,5-6H2,(H,15,21)/t9-,10+,11+,12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	5.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113756 (DGJ-NphT) Show SMILES OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)CN1C(=S)Nc1cccc2ccccc12 |r| Show InChI InChI=1S/C17H20N2O4S/c20-9-13-15(22)16(23)14(21)8-19(13)17(24)18-12-7-3-5-10-4-1-2-6-11(10)12/h1-7,13-16,20-23H,8-9H2,(H,18,24)/t13-,14+,15+,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	7.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50099009 ((3S,4S,5R)-2-Aminomethyl-5-hydroxymethyl-pyrrolidi...) Show SMILES NC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O Show InChI InChI=1S/C6H14N2O3/c7-1-3-5(10)6(11)4(2-9)8-3/h3-6,8-11H,1-2,7H2/t3-,4-,5?,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	4.6	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 4.6 after 10 mins by fluore...				Eur J Med Chem 123: 14-20 (2016) Article DOI: 10.1016/j.ejmech.2016.07.025 BindingDB Entry DOI: 10.7270/Q2RB76KN
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of human lysosome alpha-galactosidase assessed as p-nitrophenol release by spectrometric analysis				Bioorg Med Chem 18: 3790-4 (2010) Article DOI: 10.1016/j.bmc.2010.04.048 BindingDB Entry DOI: 10.7270/Q2XK8FQP
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluorescence a...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	7.0	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...				Eur J Med Chem 123: 14-20 (2016) Article DOI: 10.1016/j.ejmech.2016.07.025 BindingDB Entry DOI: 10.7270/Q2RB76KN
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	4.6	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 4.6 after 10 mins by fluore...				Eur J Med Chem 123: 14-20 (2016) Article DOI: 10.1016/j.ejmech.2016.07.025 BindingDB Entry DOI: 10.7270/Q2RB76KN
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 4.6 after 15 mins by fluorescence...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50234560 (CHEMBL4069007) Show SMILES OC[C@H]1N[C@H](CNC(=O)\C=C\c2ccc(cc2)C(F)(F)F)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C16H19F3N2O4/c17-16(18,19)10-4-1-9(2-5-10)3-6-13(23)20-7-11-14(24)15(25)12(8-22)21-11/h1-6,11-12,14-15,21-22,24-25H,7-8H2,(H,20,23)/b6-3+/t11-,12-,14-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluorescence a...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50290904 (CHEMBL4168689) Show SMILES O[C@H]1CN[C@H](CNC(=O)\C=C\c2ccc(cc2)C(F)(F)F)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C16H19F3N2O4/c17-16(18,19)10-4-1-9(2-5-10)3-6-13(23)21-7-11-14(24)15(25)12(22)8-20-11/h1-6,11-12,14-15,20,22,24-25H,7-8H2,(H,21,23)/b6-3+/t11-,12+,14+,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Yang-Ming University Curated by ChEMBL					Assay Description Inhibition of human recombinant alpha-galactosidase A using 4-MU-alpha-d-galactopyranoside as substrate by fluorescence assay				Eur J Med Chem 144: 626-634 (2018) Article DOI: 10.1016/j.ejmech.2017.12.036 BindingDB Entry DOI: 10.7270/Q2736TG9
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50564233 (CHEMBL4792854) Show SMILES O[C@@H]1CN[C@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)NC(=O)c4cc(cc(c4)C(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)C(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)nn3)cc2)[C@@H]1O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113756 (DGJ-NphT) Show SMILES OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)CN1C(=S)Nc1cccc2ccccc12 |r| Show InChI InChI=1S/C17H20N2O4S/c20-9-13-15(22)16(23)14(21)8-19(13)17(24)18-12-7-3-5-10-4-1-2-6-11(10)12/h1-7,13-16,20-23H,8-9H2,(H,18,24)/t13-,14+,15+,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	5.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50234559 (CHEMBL4081664) Show SMILES OC[C@H]1N[C@H](CNC(=O)CCCCC2CCCCC2)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H32N2O4/c20-11-14-17(23)16(22)13(19-14)10-18-15(21)9-5-4-8-12-6-2-1-3-7-12/h12-14,16-17,19-20,22-23H,1-11H2,(H,18,21)/t13-,14-,16-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluorescence a...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113760 (pF PhIM-DGJ) Show SMILES O[C@H]1CN2C(CS\C2=N\c2ccc(F)cc2)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C13H15FN2O3S/c14-7-1-3-8(4-2-7)15-13-16-5-10(17)12(19)11(18)9(16)6-20-13/h1-4,9-12,17-19H,5-6H2/b15-13+/t9?,10-,11-,12+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.18E+3	n/a	n/a	n/a	n/a	7.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50234561 (CHEMBL4090087) Show SMILES COc1ccc(Br)cc1\C=C\C(=O)NC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C16H21BrN2O5/c1-24-13-4-3-10(17)6-9(13)2-5-14(21)18-7-11-15(22)16(23)12(8-20)19-11/h2-6,11-12,15-16,19-20,22-23H,7-8H2,1H3,(H,18,21)/b5-2+/t11-,12-,15-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluorescence a...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50290907 (CHEMBL4175528) Show SMILES O[C@H]1CN[C@H](CNC(=O)CCCCC2CCCCC2)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C17H32N2O4/c20-14-11-18-13(16(22)17(14)23)10-19-15(21)9-5-4-8-12-6-2-1-3-7-12/h12-14,16-18,20,22-23H,1-11H2,(H,19,21)/t13-,14+,16+,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Yang-Ming University Curated by ChEMBL					Assay Description Inhibition of human recombinant alpha-galactosidase A using 4-MU-alpha-d-galactopyranoside as substrate by fluorescence assay				Eur J Med Chem 144: 626-634 (2018) Article DOI: 10.1016/j.ejmech.2017.12.036 BindingDB Entry DOI: 10.7270/Q2736TG9
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50564237 (CHEMBL4793095) Show SMILES O[C@@H]1CN[C@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)NC(=O)CCCCC(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)nn3)cc2)[C@@H]1O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50290905 (CHEMBL4173174) Show SMILES COc1ccc(Br)cc1\C=C\C(=O)NC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C16H21BrN2O5/c1-24-13-4-3-10(17)6-9(13)2-5-14(21)19-7-11-15(22)16(23)12(20)8-18-11/h2-6,11-12,15-16,18,20,22-23H,7-8H2,1H3,(H,19,21)/b5-2+/t11-,12+,15+,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Yang-Ming University Curated by ChEMBL					Assay Description Inhibition of human recombinant alpha-galactosidase A using 4-MU-alpha-d-galactopyranoside as substrate by fluorescence assay				Eur J Med Chem 144: 626-634 (2018) Article DOI: 10.1016/j.ejmech.2017.12.036 BindingDB Entry DOI: 10.7270/Q2736TG9
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50290903 (CHEMBL4176543) Show SMILES O[C@H]1CN[C@H](CNC(=O)CCC2CCCC2)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C14H26N2O4/c17-11-8-15-10(13(19)14(11)20)7-16-12(18)6-5-9-3-1-2-4-9/h9-11,13-15,17,19-20H,1-8H2,(H,16,18)/t10-,11+,13+,14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Yang-Ming University Curated by ChEMBL					Assay Description Inhibition of human recombinant alpha-galactosidase A using 4-MU-alpha-d-galactopyranoside as substrate by fluorescence assay				Eur J Med Chem 144: 626-634 (2018) Article DOI: 10.1016/j.ejmech.2017.12.036 BindingDB Entry DOI: 10.7270/Q2736TG9
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113761 (DGJ-BnT) Show SMILES OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)CN1C(=S)NCc1ccccc1 |r| Show InChI InChI=1S/C14H20N2O4S/c17-8-10-12(19)13(20)11(18)7-16(10)14(21)15-6-9-4-2-1-3-5-9/h1-5,10-13,17-20H,6-8H2,(H,15,21)/t10-,11+,12+,13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.41E+3	n/a	n/a	n/a	n/a	7.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase (Rattus norvegicus)	BDBM50082234 ((3R,4R,5S)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-...) Show SMILES OCC1NC(CO)[C@H](O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3?,4?,5-,6+,7+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie Organique et Analytique (I.C.O.A.) Curated by ChEMBL					Assay Description Inhibitory activity against alpha-galactosidase from rat epididymis.				Bioorg Med Chem Lett 9: 3171-4 (1999) BindingDB Entry DOI: 10.7270/Q2GT5MDZ
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50234560 (CHEMBL4069007) Show SMILES OC[C@H]1N[C@H](CNC(=O)\C=C\c2ccc(cc2)C(F)(F)F)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C16H19F3N2O4/c17-16(18,19)10-4-1-9(2-5-10)3-6-13(23)20-7-11-14(24)15(25)12(8-22)21-11/h1-6,11-12,14-15,21-22,24-25H,7-8H2,(H,20,23)/b6-3+/t11-,12-,14-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 4.6 after 15 mins by fluorescence...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50065255 ((R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol |...) Show SMILES OCC1NC(CO)[C@@H](O)C(O)C1O Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3?,4?,5-,6?,7?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibitory activity measured against alpha-galactosidase of coffee bean by colorimetric assay using the D-glucose oxidase-peroxidase method				J Med Chem 41: 2565-71 (1998) Article DOI: 10.1021/jm970836l BindingDB Entry DOI: 10.7270/Q25D8SHK
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50234563 (CHEMBL4072729) Show SMILES COc1cc(OC)c(OC)cc1CCC(=O)NC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C18H28N2O7/c1-25-13-7-15(27-3)14(26-2)6-10(13)4-5-16(22)19-8-11-17(23)18(24)12(9-21)20-11/h6-7,11-12,17-18,20-21,23-24H,4-5,8-9H2,1-3H3,(H,19,22)/t11-,12-,17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluorescence a...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50204611 (CHEMBL1289018 | D-15) Show SMILES OC[C@H]1NC[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C5H11NO3/c7-2-3-5(9)4(8)1-6-3/h3-9H,1-2H2/t3-,4-,5+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	7.0	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...				Eur J Med Chem 123: 14-20 (2016) Article DOI: 10.1016/j.ejmech.2016.07.025 BindingDB Entry DOI: 10.7270/Q2RB76KN
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113760 (pF PhIM-DGJ) Show SMILES O[C@H]1CN2C(CS\C2=N\c2ccc(F)cc2)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C13H15FN2O3S/c14-7-1-3-8(4-2-7)15-13-16-5-10(17)12(19)11(18)9(16)6-20-13/h1-4,9-12,17-19H,5-6H2/b15-13+/t9?,10-,11-,12+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.67E+3	n/a	n/a	n/a	n/a	5.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50234559 (CHEMBL4081664) Show SMILES OC[C@H]1N[C@H](CNC(=O)CCCCC2CCCCC2)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H32N2O4/c20-11-14-17(23)16(22)13(19-14)10-18-15(21)9-5-4-8-12-6-2-1-3-7-12/h12-14,16-17,19-20,22-23H,1-11H2,(H,18,21)/t13-,14-,16-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 4.6 after 15 mins by fluorescence...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50204610 (CHEMBL3908900) Show SMILES NC[C@@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H14N2O3/c7-1-3-5(10)6(11)4(2-9)8-3/h3-6,8-11H,1-2,7H2/t3-,4+,5+,6-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	7.0	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...				Eur J Med Chem 123: 14-20 (2016) Article DOI: 10.1016/j.ejmech.2016.07.025 BindingDB Entry DOI: 10.7270/Q2RB76KN
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50564249 (CHEMBL4789325) Show SMILES O[C@@H]1CN[C@H](Cn2cc(CCCn3cc(COCC(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)NC(=O)c4cc(cc(c4)C(=O)NC(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)C(=O)NC(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)nn3)nn2)[C@@H]1O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50290906 (CHEMBL4165270) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]-[#6](=O)-[#7]-[#6]-[#6@H]-1-[#7]-[#6]-[#6@H](-[#8])-[#6@@H](-[#8])-[#6@H]-1-[#8] |r| Show InChI InChI=1S/C16H30N2O4/c1-10(2)5-4-6-11(3)7-14(20)18-8-12-15(21)16(22)13(19)9-17-12/h5,11-13,15-17,19,21-22H,4,6-9H2,1-3H3,(H,18,20)/t11?,12-,13+,15+,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Yang-Ming University Curated by ChEMBL					Assay Description Inhibition of human recombinant alpha-galactosidase A using 4-MU-alpha-d-galactopyranoside as substrate by fluorescence assay				Eur J Med Chem 144: 626-634 (2018) Article DOI: 10.1016/j.ejmech.2017.12.036 BindingDB Entry DOI: 10.7270/Q2736TG9
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50234565 (CHEMBL4093453) Show SMILES COc1cccc(CCC(=O)NC[C@H]2N[C@H](CO)[C@H](O)[C@@H]2O)c1 |r| Show InChI InChI=1S/C16H24N2O5/c1-23-11-4-2-3-10(7-11)5-6-14(20)17-8-12-15(21)16(22)13(9-19)18-12/h2-4,7,12-13,15-16,18-19,21-22H,5-6,8-9H2,1H3,(H,17,20)/t12-,13-,15-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluorescence a...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50204609 (CHEMBL3985941) Show SMILES NC[C@H]1N[C@@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H14N2O3/c7-1-3-5(10)6(11)4(2-9)8-3/h3-6,8-11H,1-2,7H2/t3-,4+,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	7.0	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...				Eur J Med Chem 123: 14-20 (2016) Article DOI: 10.1016/j.ejmech.2016.07.025 BindingDB Entry DOI: 10.7270/Q2RB76KN
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50320826 (CHEMBL1163255 | beta-1-C-Butyl-1-deoxygalactonojir...) Show SMILES CCCC[C@@H]1N[C@H](CO)[C@H](O)[C@H](O)[C@H]1C |r| Show InChI InChI=1S/C11H23NO3/c1-3-4-5-8-7(2)10(14)11(15)9(6-13)12-8/h7-15H,3-6H2,1-2H3/t7-,8-,9+,10+,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of human lysosome alpha-galactosidase assessed as p-nitrophenol release by spectrometric analysis				Bioorg Med Chem 18: 3790-4 (2010) Article DOI: 10.1016/j.bmc.2010.04.048 BindingDB Entry DOI: 10.7270/Q2XK8FQP
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50564236 (CHEMBL4782789) Show SMILES O[C@@H]1CN[C@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(COCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cnnn4CCOCCOc4ccc(cc4)-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)nn3)cc2)[C@@H]1O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50564235 (CHEMBL4793871) Show SMILES NC(COCc1cn(CCOCCOc2ccc(cc2)-c2cn(C[C@H]3NC[C@@H](O)[C@H]3O)nn2)nn1)(COCc1cn(CCOCCOc2ccc(cc2)-c2cn(C[C@H]3NC[C@@H](O)[C@H]3O)nn2)nn1)COCc1cn(CCOCCOc2ccc(cc2)-c2cn(C[C@H]3NC[C@@H](O)[C@H]3O)nn2)nn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112173 BindingDB Entry DOI: 10.7270/Q2H998X6
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50234565 (CHEMBL4093453) Show SMILES COc1cccc(CCC(=O)NC[C@H]2N[C@H](CO)[C@H](O)[C@@H]2O)c1 |r| Show InChI InChI=1S/C16H24N2O5/c1-23-11-4-2-3-10(7-11)5-6-14(20)17-8-12-15(21)16(22)13(9-19)18-12/h2-4,7,12-13,15-16,18-19,21-22H,5-6,8-9H2,1H3,(H,17,20)/t12-,13-,15-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 4.6 after 15 mins by fluorescence...				Eur J Med Chem 126: 1-6 (2017) Article DOI: 10.1016/j.ejmech.2016.10.004 BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM113761 (DGJ-BnT) Show SMILES OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)CN1C(=S)NCc1ccccc1 |r| Show InChI InChI=1S/C14H20N2O4S/c17-8-10-12(19)13(20)11(18)7-16(10)14(21)15-6-9-4-2-1-3-5-9/h1-5,10-13,17-20H,6-8H2,(H,15,21)/t10-,11+,12+,13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	5.0	n/a
Tottori University , Yonago 683-8503, Japan					Assay Description For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...				ACS Chem Biol 9: 1460-9 (2014) Article DOI: 10.1021/cb500143h BindingDB Entry DOI: 10.7270/Q2XS5T16
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50204613 (CHEMBL3929052) Show SMILES CC(=O)NC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C8H16N2O4/c1-4(12)9-2-5-7(13)8(14)6(3-11)10-5/h5-8,10-11,13-14H,2-3H2,1H3,(H,9,12)/t5-,6-,7-,8+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.21E+4	n/a	n/a	n/a	n/a	7.0	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...				Eur J Med Chem 123: 14-20 (2016) Article DOI: 10.1016/j.ejmech.2016.07.025 BindingDB Entry DOI: 10.7270/Q2RB76KN
					More data for this Ligand-Target Pair

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