Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Francisella tularensis) | BDBM24777 (5-hydroxy-1,4-dihydronaphthalene-1,4-dione | 5-hyd...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Brookhaven National Laboratory | Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ... | Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Francisella tularensis) | BDBM50214969 (1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Brookhaven National Laboratory | Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ... | Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Francisella tularensis) | BDBM50056922 (1,4-Dihydroxy-10-methoxy-5,8-dimethyl-3,7-dioxo-1,...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.78E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Brookhaven National Laboratory | Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ... | Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Francisella tularensis) | BDBM11318 (1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.31E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Brookhaven National Laboratory | Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ... | Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1 | |||||||||||
More data for this Ligand-Target Pair |