Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM203869 (7-(3-((4-Borono-3-formylphenoxy)methyl)-1,5-dimeth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.900 | -51.5 | 3.40 | n/a | n/a | n/a | n/a | 7.4 | 24 |
Oncology Innovative Medicines Unit | Assay Description TR-FRET assay was used to assess the ability of compounds to disrupt the interaction between recombinant human Mcl-1 and a labeled BIM peptide probe.... | Nat Chem Biol 12: 931-936 (2016) Article DOI: 10.1038/nchembio.2174 BindingDB Entry DOI: 10.7270/Q2FN1513 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM203875 (7-(3-((4-Borono-3-formylphenoxy)methyl)-1,5-dimeth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.20 | -50.7 | 4.20 | n/a | n/a | n/a | n/a | 7.4 | 24 |
Oncology Innovative Medicines Unit | Assay Description TR-FRET assay was used to assess the ability of compounds to disrupt the interaction between recombinant human Mcl-1 and a labeled BIM peptide probe.... | Nat Chem Biol 12: 931-936 (2016) Article DOI: 10.1038/nchembio.2174 BindingDB Entry DOI: 10.7270/Q2FN1513 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM203870 (7-(3-((3-Acetyl-4-boronophenoxy)methyl)-1,5-dimeth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.20 | -50.7 | 4.70 | n/a | n/a | n/a | n/a | 7.4 | 24 |
Oncology Innovative Medicines Unit | Assay Description TR-FRET assay was used to assess the ability of compounds to disrupt the interaction between recombinant human Mcl-1 and a labeled BIM peptide probe.... | Nat Chem Biol 12: 931-936 (2016) Article DOI: 10.1038/nchembio.2174 BindingDB Entry DOI: 10.7270/Q2FN1513 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM203876 (Mcl-1 inhibitor 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.60 | -50.0 | 5.96 | n/a | n/a | n/a | n/a | 7.4 | 24 |
Oncology Innovative Medicines Unit | Assay Description TR-FRET assay was used to assess the ability of compounds to disrupt the interaction between recombinant human Mcl-1 and a labeled BIM peptide probe.... | Nat Chem Biol 12: 931-936 (2016) Article DOI: 10.1038/nchembio.2174 BindingDB Entry DOI: 10.7270/Q2FN1513 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM203871 (7-(3-((3-formylphenoxy)methyl)-1,5-dimethyl-1H-pyr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 16 | -44.3 | 59.5 | n/a | n/a | n/a | n/a | 7.4 | 24 |
Oncology Innovative Medicines Unit | Assay Description TR-FRET assay was used to assess the ability of compounds to disrupt the interaction between recombinant human Mcl-1 and a labeled BIM peptide probe.... | Nat Chem Biol 12: 931-936 (2016) Article DOI: 10.1038/nchembio.2174 BindingDB Entry DOI: 10.7270/Q2FN1513 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM203873 (7-(3-((4-Boronophenoxy)methyl)-1,5-dimethyl-1H-pyr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 44 | -41.8 | 162 | n/a | n/a | n/a | n/a | 7.4 | 24 |
Oncology Innovative Medicines Unit | Assay Description TR-FRET assay was used to assess the ability of compounds to disrupt the interaction between recombinant human Mcl-1 and a labeled BIM peptide probe.... | Nat Chem Biol 12: 931-936 (2016) Article DOI: 10.1038/nchembio.2174 BindingDB Entry DOI: 10.7270/Q2FN1513 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM203872 (7-(3-((3-Acetylphenoxy)methyl)-1,5-dimethyl-1H-pyr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 64 | -40.9 | 237 | n/a | n/a | n/a | n/a | 7.4 | 24 |
Oncology Innovative Medicines Unit | Assay Description TR-FRET assay was used to assess the ability of compounds to disrupt the interaction between recombinant human Mcl-1 and a labeled BIM peptide probe.... | Nat Chem Biol 12: 931-936 (2016) Article DOI: 10.1038/nchembio.2174 BindingDB Entry DOI: 10.7270/Q2FN1513 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM203874 (Mcl-1 inhibitor 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 104 | -39.7 | 383 | n/a | n/a | n/a | n/a | 7.4 | 24 |
Oncology Innovative Medicines Unit | Assay Description TR-FRET assay was used to assess the ability of compounds to disrupt the interaction between recombinant human Mcl-1 and a labeled BIM peptide probe.... | Nat Chem Biol 12: 931-936 (2016) Article DOI: 10.1038/nchembio.2174 BindingDB Entry DOI: 10.7270/Q2FN1513 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449620 (US10703733, Example 233 | US10988451, Example 233) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0160 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449686 (US10703733, Example 299 | US10988451, Example 298 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0160 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449627 (US10703733, Example 240 | US10988451, Example 240) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0180 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449659 (US10703733, Example 272 | US10988451, Example 272 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0180 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449730 (US10703733, Example 343 | US10988451, Example 343 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM493822 (US10988451, Example 292) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449559 (US10703733, Example 172 | US10988451, Example 172 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0220 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449749 (US10703733, Example 362 | US10988451, Example 362 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0240 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449698 (US10703733, Example 311 | US10988451, Example 311 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0240 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449548 (US10703733, Example 161 | US10988451, Example 161 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0250 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449687 (US10703733, Example 300 | US10988451, Example 300 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0260 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449736 (US10703733, Example 349 | US10988451, Example 349 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0260 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM471418 (US10821115, Example 100433 | US11224601, Example 1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0260 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan... | US Patent US10821115 (2020) BindingDB Entry DOI: 10.7270/Q23T9MB5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449617 (US10703733, Example 230 | US10988451, Example 230) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0270 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449637 (US10703733, Example 250 | US10988451, Example 250) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0290 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449729 (US10703733, Example 342 | US10988451, Example 342 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0290 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449696 (US10703733, Example 309 | US10988451, Example 309 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0290 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449674 (US10703733, Example 287 | US10988451, Example 287 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0290 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449670 (US10703733, Example 283 | US10988451, Example 283 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0290 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449677 (US10703733, Example 290 | US10988451, Example 290 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449654 (US10703733, Example 267 | US10988451, Example 267 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449577 (US10703733, Example 190 | US10703733, Example 194 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM493759 (US10988451, Example 229 | US11643400, Example 229) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449717 (US10703733, Example 330 | US10988451, Example 330 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449727 (US10703733, Example 340 | US10988451, Example 340 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0310 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM470886 ((1S,3'R,6'R,7'S,8'E,11'S,12'R)- 6-chloro-7'-methox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0310 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan... | US Patent US10821115 (2020) BindingDB Entry DOI: 10.7270/Q23T9MB5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM471530 (US10821115, Example 100547 | US11224601, Example 1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0310 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan... | US Patent US10821115 (2020) BindingDB Entry DOI: 10.7270/Q23T9MB5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449695 (US10703733, Example 308 | US10988451, Example 308 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0310 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449547 (US10703733, Example 160 | US10703733, Example 195 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0310 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449733 (US10703733, Example 346 | US10988451, Example 346 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0310 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449757 (US10703733, Example 376 | US10988451, Example 376 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0310 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM471007 (US10821115, Example 100020 | US10821115, Example 1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0320 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan... | US Patent US10821115 (2020) BindingDB Entry DOI: 10.7270/Q23T9MB5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449631 (US10703733, Example 244 | US10988451, Example 244) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0320 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449728 (US10703733, Example 341 | US10988451, Example 341 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0320 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM493719 (US10988451, Example 189) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0330 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449558 (US10703733, Example 171 | US10988451, Example 171 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0330 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM471293 (US10821115, Example 100308 | US10821115, Example 1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0330 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan... | US Patent US10821115 (2020) BindingDB Entry DOI: 10.7270/Q23T9MB5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM493827 (US10988451, Example 297 | US11643400, Example 297) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0330 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449625 (US10703733, Example 238 | US10988451, Example 238) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0330 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449704 (US10703733, Example 317 | US10988451, Example 317 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0340 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449552 (US10703733, Example 165 | US10988451, Example 165 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0350 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human)) | BDBM449801 (US10703733, Example 422 | US10988451, Example 422) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0350 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. US Patent | Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17... | US Patent US10988451 (2021) BindingDB Entry DOI: 10.7270/Q2M048KN | |||||||||||
More data for this Ligand-Target Pair |
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