BindingDB PrimarySearch

Found 504 hits Enz. Inhib. hit(s) with Target = 'Proteasome component C5'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50599558 (CHEMBL5182929) Show SMILES O=C(CCn1ccccc1=O)NCc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128478 BindingDB Entry DOI: 10.7270/Q20R9TGT
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128478 BindingDB Entry DOI: 10.7270/Q20R9TGT
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 20s immunoproteasome beta1 caspase-like activity in human spleen using Ac-Pro-Ala-Leu-AMC as substrate after 10 mins by fluorescence as...				Citation and Details Article DOI: 10.1016/j.bmcl.2017.12.053 BindingDB Entry DOI: 10.7270/Q29W0J2W
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50021350 (CHEMBL3287940) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50599556 (CHEMBL5182479) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128478 BindingDB Entry DOI: 10.7270/Q20R9TGT
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50021352 (CHEMBL3287943) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50444909 (CHEMBL3099618) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bio-Science and Technology Curated by ChEMBL					Assay Description Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...				Eur J Med Chem 71: 290-305 (2014) Article DOI: 10.1016/j.ejmech.2013.11.009 BindingDB Entry DOI: 10.7270/Q2222W81
Institute of Bio-Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasome				J Med Chem 49: 2953-68 (2006) Article DOI: 10.1021/jm058289o BindingDB Entry DOI: 10.7270/Q2FF3S0S
Celera Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50434766 (CHEMBL2385812) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...				Eur J Med Chem 64: 23-34 (2013) Article DOI: 10.1016/j.ejmech.2013.03.032 BindingDB Entry DOI: 10.7270/Q2S46TC8
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50444908 (CHEMBL3099624) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bio-Science and Technology Curated by ChEMBL					Assay Description Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...				Eur J Med Chem 71: 290-305 (2014) Article DOI: 10.1016/j.ejmech.2013.11.009 BindingDB Entry DOI: 10.7270/Q2222W81
Institute of Bio-Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50021348 (CHEMBL3287937) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50021349 (CHEMBL3287939) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50444888 (CHEMBL3099621) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bio-Science and Technology Curated by ChEMBL					Assay Description Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...				Eur J Med Chem 71: 290-305 (2014) Article DOI: 10.1016/j.ejmech.2013.11.009 BindingDB Entry DOI: 10.7270/Q2222W81
Institute of Bio-Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50021351 (CHEMBL3287942) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50434768 (CHEMBL2385810) Show SMILES CC(C)C[C@H](NC(=O)Cn1ccccc1=O)B(O)O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...				Eur J Med Chem 64: 23-34 (2013) Article DOI: 10.1016/j.ejmech.2013.03.032 BindingDB Entry DOI: 10.7270/Q2S46TC8
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50434765 (CHEMBL2385813) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...				Eur J Med Chem 64: 23-34 (2013) Article DOI: 10.1016/j.ejmech.2013.03.032 BindingDB Entry DOI: 10.7270/Q2S46TC8
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50434763 (CHEMBL2385817) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50434763 (CHEMBL2385817) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...				Eur J Med Chem 64: 23-34 (2013) Article DOI: 10.1016/j.ejmech.2013.03.032 BindingDB Entry DOI: 10.7270/Q2S46TC8
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50021353 (CHEMBL3287944) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50453681 (CHEMBL4204445) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	2.64E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 20s immunoproteasome beta1 caspase-like activity in human spleen using Ac-Pro-Ala-Leu-AMC as substrate after 10 mins by fluorescence as...				Citation and Details Article DOI: 10.1016/j.bmcl.2017.12.053 BindingDB Entry DOI: 10.7270/Q29W0J2W
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50599552 (CHEMBL5195299) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128478 BindingDB Entry DOI: 10.7270/Q20R9TGT
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50434760 (CHEMBL2385820) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...				Eur J Med Chem 64: 23-34 (2013) Article DOI: 10.1016/j.ejmech.2013.03.032 BindingDB Entry DOI: 10.7270/Q2S46TC8
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50434767 (CHEMBL2385811) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...				Eur J Med Chem 64: 23-34 (2013) Article DOI: 10.1016/j.ejmech.2013.03.032 BindingDB Entry DOI: 10.7270/Q2S46TC8
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50021356 (CHEMBL3287947) Show SMILES CC(C)CCNC(=O)Cn1ccc2ccc(Br)cc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128478 BindingDB Entry DOI: 10.7270/Q20R9TGT
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50434764 (CHEMBL2385814) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...				Eur J Med Chem 64: 23-34 (2013) Article DOI: 10.1016/j.ejmech.2013.03.032 BindingDB Entry DOI: 10.7270/Q2S46TC8
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...				Eur J Med Chem 121: 578-591 (2016) Article DOI: 10.1016/j.ejmech.2016.05.049 BindingDB Entry DOI: 10.7270/Q28C9Z6K
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50453645 (CHEMBL4212662) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.53E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 20s immunoproteasome beta1 caspase-like activity in human spleen using Ac-Pro-Ala-Leu-AMC as substrate after 10 mins by fluorescence as...				Citation and Details Article DOI: 10.1016/j.bmcl.2017.12.053 BindingDB Entry DOI: 10.7270/Q29W0J2W
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-6 (Saccharomyces cerevisiae)	BDBM50185622 (Apam-YET \| CHEMBL210325) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-Université Paris VI Curated by ChEMBL					Assay Description Inhibition of post acid activity of yeast 20S proteasome				Bioorg Med Chem Lett 16: 3277-81 (2006) Article DOI: 10.1016/j.bmcl.2006.03.033 BindingDB Entry DOI: 10.7270/Q280527Z
CNRS-Université Paris VI Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50195934 (CHEMBL3977256) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.59E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...				Eur J Med Chem 121: 578-591 (2016) Article DOI: 10.1016/j.ejmech.2016.05.049 BindingDB Entry DOI: 10.7270/Q28C9Z6K
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50453650 (CHEMBL4213821) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.64E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 20s constitutive proteasome beta1 caspase-like activity in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate after 10 mins by flu...				Citation and Details Article DOI: 10.1016/j.bmcl.2017.12.053 BindingDB Entry DOI: 10.7270/Q29W0J2W
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50599551 (CHEMBL5207762) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128478 BindingDB Entry DOI: 10.7270/Q20R9TGT
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50434762 (CHEMBL2385818) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...				Eur J Med Chem 64: 23-34 (2013) Article DOI: 10.1016/j.ejmech.2013.03.032 BindingDB Entry DOI: 10.7270/Q2S46TC8
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50410909 (CHEMBL207591 \| PSI) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasome				J Med Chem 49: 2953-68 (2006) Article DOI: 10.1021/jm058289o BindingDB Entry DOI: 10.7270/Q2FF3S0S
Celera Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50599553 (CHEMBL5198329) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128478 BindingDB Entry DOI: 10.7270/Q20R9TGT
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-6 (Saccharomyces cerevisiae)	BDBM50185630 (CHEMBL210871 \| Pam-YDL) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-Université Paris VI Curated by ChEMBL					Assay Description Inhibition of post acid activity of yeast 20S proteasome				Bioorg Med Chem Lett 16: 3277-81 (2006) Article DOI: 10.1016/j.bmcl.2006.03.033 BindingDB Entry DOI: 10.7270/Q280527Z
CNRS-Université Paris VI Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-6 (Saccharomyces cerevisiae)	BDBM50185643 ((S)-2-{(S)-4-carboxy-2-[(S)-2-hexadecanoylamino-3-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-Université Paris VI Curated by ChEMBL					Assay Description Inhibition of post acid activity of yeast 20S proteasome				Bioorg Med Chem Lett 16: 3277-81 (2006) Article DOI: 10.1016/j.bmcl.2006.03.033 BindingDB Entry DOI: 10.7270/Q280527Z
CNRS-Université Paris VI Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50599551 (CHEMBL5207762) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128478 BindingDB Entry DOI: 10.7270/Q20R9TGT
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50434761 (CHEMBL2385819) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50434761 (CHEMBL2385819) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...				Eur J Med Chem 64: 23-34 (2013) Article DOI: 10.1016/j.ejmech.2013.03.032 BindingDB Entry DOI: 10.7270/Q2S46TC8
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-6 (Saccharomyces cerevisiae)	BDBM50185650 (CHEMBL209568 \| Pam-YET) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-Université Paris VI Curated by ChEMBL					Assay Description Inhibition of post acid activity of yeast 20S proteasome				Bioorg Med Chem Lett 16: 3277-81 (2006) Article DOI: 10.1016/j.bmcl.2006.03.033 BindingDB Entry DOI: 10.7270/Q280527Z
CNRS-Université Paris VI Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2.21E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128478 BindingDB Entry DOI: 10.7270/Q20R9TGT
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2.21E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 20s constitutive proteasome beta1 caspase-like activity in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate after 10 mins by flu...				Citation and Details Article DOI: 10.1016/j.bmcl.2017.12.053 BindingDB Entry DOI: 10.7270/Q29W0J2W
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50007719 (CHEMBL3233441) Show SMILES CC(C)CCNC(=O)Cn1cc(Br)c2ncccc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of caspase-like activity of human 20S proteasome beta 1 subunit assessed as Cbz-Leu-Leu-Glu-AMC substrate hydrolysis after 10 mins by fluo...				Eur J Med Chem 76: 1-9 (2014) Article DOI: 10.1016/j.ejmech.2014.01.022 BindingDB Entry DOI: 10.7270/Q23N24XM
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50599552 (CHEMBL5195299) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128478 BindingDB Entry DOI: 10.7270/Q20R9TGT
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50195936 (CHEMBL3612420) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.13E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...				Eur J Med Chem 121: 578-591 (2016) Article DOI: 10.1016/j.ejmech.2016.05.049 BindingDB Entry DOI: 10.7270/Q28C9Z6K
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50069984 ((R)-1-((S)-2-((S)-2-(benzyloxycarbonyl)-4-methylpe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasome				J Med Chem 49: 2953-68 (2006) Article DOI: 10.1021/jm058289o BindingDB Entry DOI: 10.7270/Q2FF3S0S
Celera Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50599554 (CHEMBL5172870) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128478 BindingDB Entry DOI: 10.7270/Q20R9TGT
TBA					More data for this Ligand-Target Pair
Proteasome subunit beta type-6 (Saccharomyces cerevisiae)	BDBM50185638 ((S)-2-{(S)-4-Carboxy-2-[(S)-2-hexanoylamino-3-(4-h...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-Université Paris VI Curated by ChEMBL					Assay Description Inhibition of post acid activity of yeast 20S proteasome				Bioorg Med Chem Lett 16: 3277-81 (2006) Article DOI: 10.1016/j.bmcl.2006.03.033 BindingDB Entry DOI: 10.7270/Q280527Z
CNRS-Université Paris VI Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-6 (Saccharomyces cerevisiae)	BDBM50185628 ((S)-2-{(S)-4-carboxy-2-[(S)-2-dodecanoylamino-3-(4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-Université Paris VI Curated by ChEMBL					Assay Description Inhibition of post acid activity of yeast 20S proteasome				Bioorg Med Chem Lett 16: 3277-81 (2006) Article DOI: 10.1016/j.bmcl.2006.03.033 BindingDB Entry DOI: 10.7270/Q280527Z
CNRS-Université Paris VI Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-6 (Saccharomyces cerevisiae)	BDBM50185632 ((S)-2-{(S)-4-carboxy-2-[(S)-2-decanoylamino-3-(4-h...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-Université Paris VI Curated by ChEMBL					Assay Description Inhibition of post acid activity of yeast 20S proteasome				Bioorg Med Chem Lett 16: 3277-81 (2006) Article DOI: 10.1016/j.bmcl.2006.03.033 BindingDB Entry DOI: 10.7270/Q280527Z
CNRS-Université Paris VI Curated by ChEMBL					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 504 total ) | Next | Last >>