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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Aurora kinase A (Homo sapiens (Human)) | BDBM155569 (US10092556, Example 13 | US9012475, 13 | US9346787...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM155565 (US10092556, Example 1 | US9012475, 1 | US9346787, ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM155568 (US10092556, Example 12 | US9012475, 12 | US9346787...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM155566 (US10092556, Example 2 | US9012475, 2 | US9346787, ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM155574 (US10092556, Example 24 | US9012475, 24 | US9346787...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM47238 (US9012475, MLN8237) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM155567 (US10092556, Example 11 | US9012475, 11 | US9346787...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM155575 (US10092556, Example 28 | US9012475, 28 | US9346787...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM155573 (US10092556, Example 22 | US9012475, 22 | US9346787...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM155576 (US10092556, Example 29 | US9012475, 29 | US9346787...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM155571 (US10092556, Example 17 | US9012475, 17 | US9346787...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM155570 (US10092556, Example 14 | US9012475, 14 | US9346787...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM155572 (US10092556, Example 19 | US9012475, 19 | US9346787...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM47238 (US9012475, MLN8237) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 90 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155565 (US10092556, Example 1 | US9012475, 1 | US9346787, ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 140 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155569 (US10092556, Example 13 | US9012475, 13 | US9346787...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 180 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155574 (US10092556, Example 24 | US9012475, 24 | US9346787...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 190 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155568 (US10092556, Example 12 | US9012475, 12 | US9346787...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 260 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155566 (US10092556, Example 2 | US9012475, 2 | US9346787, ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 340 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155573 (US10092556, Example 22 | US9012475, 22 | US9346787...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 380 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155576 (US10092556, Example 29 | US9012475, 29 | US9346787...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 390 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155575 (US10092556, Example 28 | US9012475, 28 | US9346787...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 450 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155570 (US10092556, Example 14 | US9012475, 14 | US9346787...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 460 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155572 (US10092556, Example 19 | US9012475, 19 | US9346787...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 880 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155571 (US10092556, Example 17 | US9012475, 17 | US9346787...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 900 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM155567 (US10092556, Example 11 | US9012475, 11 | US9346787...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 930 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca... | US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
