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PubMed code 11327599

Compile data set for download or QSAR
Found 25 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C, epsilon


(Homo sapiens (Human))
BDBM50099066
PNG
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
Show SMILES CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(C)=O |r,c:33,t:22|
Show InChI InChI=1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30?,32-,34-,35-,36-/m1/s1
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0.450n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C epsilon


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50099066
PNG
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
Show SMILES CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(C)=O |r,c:33,t:22|
Show InChI InChI=1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30?,32-,34-,35-,36-/m1/s1
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0.800n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C delta


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
PKC alpha and beta-2


(Homo sapiens (Human))
BDBM50099066
PNG
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
Show SMILES CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(C)=O |r,c:33,t:22|
Show InChI InChI=1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30?,32-,34-,35-,36-/m1/s1
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1.80n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C beta


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50099066
PNG
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
Show SMILES CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(C)=O |r,c:33,t:22|
Show InChI InChI=1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30?,32-,34-,35-,36-/m1/s1
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2.5n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C alpha


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C, gamma


(Homo sapiens (Human))
BDBM50099066
PNG
(CHEMBL279115 | phorbol 13-acetate 12-myristate)
Show SMILES CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(C)=O |r,c:33,t:22|
Show InChI InChI=1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30?,32-,34-,35-,36-/m1/s1
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4.90n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C gamma


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50057509
PNG
((2S,5S)-8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1...)
Show SMILES CCCCCCCCC#Cc1ccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)Cc2c1
Show InChI InChI=1S/C25H38N2O2/c1-5-6-7-8-9-10-11-12-13-20-14-15-23-21(16-20)17-22(18-28)26-25(29)24(19(2)3)27(23)4/h14-16,19,22,24,28H,5-11,17-18H2,1-4H3,(H,26,29)/t22-,24-/m0/s1
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23n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C alpha


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C, epsilon


(Homo sapiens (Human))
BDBM50057509
PNG
((2S,5S)-8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1...)
Show SMILES CCCCCCCCC#Cc1ccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)Cc2c1
Show InChI InChI=1S/C25H38N2O2/c1-5-6-7-8-9-10-11-12-13-20-14-15-23-21(16-20)17-22(18-28)26-25(29)24(19(2)3)27(23)4/h14-16,19,22,24,28H,5-11,17-18H2,1-4H3,(H,26,29)/t22-,24-/m0/s1
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40n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C epsilon


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C, gamma


(Homo sapiens (Human))
BDBM50057509
PNG
((2S,5S)-8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1...)
Show SMILES CCCCCCCCC#Cc1ccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)Cc2c1
Show InChI InChI=1S/C25H38N2O2/c1-5-6-7-8-9-10-11-12-13-20-14-15-23-21(16-20)17-22(18-28)26-25(29)24(19(2)3)27(23)4/h14-16,19,22,24,28H,5-11,17-18H2,1-4H3,(H,26,29)/t22-,24-/m0/s1
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43n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C gamma


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
PKC alpha and beta-2


(Homo sapiens (Human))
BDBM50057509
PNG
((2S,5S)-8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1...)
Show SMILES CCCCCCCCC#Cc1ccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)Cc2c1
Show InChI InChI=1S/C25H38N2O2/c1-5-6-7-8-9-10-11-12-13-20-14-15-23-21(16-20)17-22(18-28)26-25(29)24(19(2)3)27(23)4/h14-16,19,22,24,28H,5-11,17-18H2,1-4H3,(H,26,29)/t22-,24-/m0/s1
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70n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C beta


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50057509
PNG
((2S,5S)-8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1...)
Show SMILES CCCCCCCCC#Cc1ccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)Cc2c1
Show InChI InChI=1S/C25H38N2O2/c1-5-6-7-8-9-10-11-12-13-20-14-15-23-21(16-20)17-22(18-28)26-25(29)24(19(2)3)27(23)4/h14-16,19,22,24,28H,5-11,17-18H2,1-4H3,(H,26,29)/t22-,24-/m0/s1
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114n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C delta


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50099067
PNG
(CHEMBL173348 | Dodecanoic acid (3S,3aR,8S,8aS)-3-h...)
Show SMILES CCCCCCCCCCCC(=O)Oc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@](C)(C(C)C)c2c1
Show InChI InChI=1S/C28H43NO4/c1-5-6-7-8-9-10-11-12-13-14-24(31)33-20-15-16-21-22(17-20)28(4,19(2)3)26-25(21)23(18-30)29-27(26)32/h15-17,19,23,25-26,30H,5-14,18H2,1-4H3,(H,29,32)/t23-,25-,26-,28-/m1/s1
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150n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C delta


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C, gamma


(Homo sapiens (Human))
BDBM50099064
PNG
(CHEMBL368720 | Dodecanoic acid (3S,3aR,8R,8aS)-3-h...)
Show SMILES CCCCCCCCCCCC(=O)Oc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@@](C)(C(C)C)c2c1
Show InChI InChI=1S/C28H43NO4/c1-5-6-7-8-9-10-11-12-13-14-24(31)33-20-15-16-21-22(17-20)28(4,19(2)3)26-25(21)23(18-30)29-27(26)32/h15-17,19,23,25-26,30H,5-14,18H2,1-4H3,(H,29,32)/t23-,25-,26-,28+/m1/s1
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209n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C gamma


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C, epsilon


(Homo sapiens (Human))
BDBM50099067
PNG
(CHEMBL173348 | Dodecanoic acid (3S,3aR,8S,8aS)-3-h...)
Show SMILES CCCCCCCCCCCC(=O)Oc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@](C)(C(C)C)c2c1
Show InChI InChI=1S/C28H43NO4/c1-5-6-7-8-9-10-11-12-13-14-24(31)33-20-15-16-21-22(17-20)28(4,19(2)3)26-25(21)23(18-30)29-27(26)32/h15-17,19,23,25-26,30H,5-14,18H2,1-4H3,(H,29,32)/t23-,25-,26-,28-/m1/s1
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228n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C epsilon


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C, gamma


(Homo sapiens (Human))
BDBM50099065
PNG
((3S,3aR,8R,8aS)-6-Dec-1-ynyl-3-hydroxymethyl-8-iso...)
Show SMILES CCCCCCCCC#Cc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@@](C)(C(C)C)c2c1
Show InChI InChI=1S/C26H37NO2/c1-5-6-7-8-9-10-11-12-13-19-14-15-20-21(16-19)26(4,18(2)3)24-23(20)22(17-28)27-25(24)29/h14-16,18,22-24,28H,5-11,17H2,1-4H3,(H,27,29)/t22-,23-,24-,26+/m1/s1
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279n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C gamma


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C, gamma


(Homo sapiens (Human))
BDBM50099067
PNG
(CHEMBL173348 | Dodecanoic acid (3S,3aR,8S,8aS)-3-h...)
Show SMILES CCCCCCCCCCCC(=O)Oc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@](C)(C(C)C)c2c1
Show InChI InChI=1S/C28H43NO4/c1-5-6-7-8-9-10-11-12-13-14-24(31)33-20-15-16-21-22(17-20)28(4,19(2)3)26-25(21)23(18-30)29-27(26)32/h15-17,19,23,25-26,30H,5-14,18H2,1-4H3,(H,29,32)/t23-,25-,26-,28-/m1/s1
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327n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C gamma


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50099064
PNG
(CHEMBL368720 | Dodecanoic acid (3S,3aR,8R,8aS)-3-h...)
Show SMILES CCCCCCCCCCCC(=O)Oc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@@](C)(C(C)C)c2c1
Show InChI InChI=1S/C28H43NO4/c1-5-6-7-8-9-10-11-12-13-14-24(31)33-20-15-16-21-22(17-20)28(4,19(2)3)26-25(21)23(18-30)29-27(26)32/h15-17,19,23,25-26,30H,5-14,18H2,1-4H3,(H,29,32)/t23-,25-,26-,28+/m1/s1
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395n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C alpha


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C, epsilon


(Homo sapiens (Human))
BDBM50099065
PNG
((3S,3aR,8R,8aS)-6-Dec-1-ynyl-3-hydroxymethyl-8-iso...)
Show SMILES CCCCCCCCC#Cc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@@](C)(C(C)C)c2c1
Show InChI InChI=1S/C26H37NO2/c1-5-6-7-8-9-10-11-12-13-19-14-15-20-21(16-19)26(4,18(2)3)24-23(20)22(17-28)27-25(24)29/h14-16,18,22-24,28H,5-11,17H2,1-4H3,(H,27,29)/t22-,23-,24-,26+/m1/s1
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469n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C epsilon


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C, epsilon


(Homo sapiens (Human))
BDBM50099064
PNG
(CHEMBL368720 | Dodecanoic acid (3S,3aR,8R,8aS)-3-h...)
Show SMILES CCCCCCCCCCCC(=O)Oc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@@](C)(C(C)C)c2c1
Show InChI InChI=1S/C28H43NO4/c1-5-6-7-8-9-10-11-12-13-14-24(31)33-20-15-16-21-22(17-20)28(4,19(2)3)26-25(21)23(18-30)29-27(26)32/h15-17,19,23,25-26,30H,5-14,18H2,1-4H3,(H,29,32)/t23-,25-,26-,28+/m1/s1
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515n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C epsilon


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50099065
PNG
((3S,3aR,8R,8aS)-6-Dec-1-ynyl-3-hydroxymethyl-8-iso...)
Show SMILES CCCCCCCCC#Cc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@@](C)(C(C)C)c2c1
Show InChI InChI=1S/C26H37NO2/c1-5-6-7-8-9-10-11-12-13-19-14-15-20-21(16-19)26(4,18(2)3)24-23(20)22(17-28)27-25(24)29/h14-16,18,22-24,28H,5-11,17H2,1-4H3,(H,27,29)/t22-,23-,24-,26+/m1/s1
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580n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C alpha


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
PKC alpha and beta-2


(Homo sapiens (Human))
BDBM50099064
PNG
(CHEMBL368720 | Dodecanoic acid (3S,3aR,8R,8aS)-3-h...)
Show SMILES CCCCCCCCCCCC(=O)Oc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@@](C)(C(C)C)c2c1
Show InChI InChI=1S/C28H43NO4/c1-5-6-7-8-9-10-11-12-13-14-24(31)33-20-15-16-21-22(17-20)28(4,19(2)3)26-25(21)23(18-30)29-27(26)32/h15-17,19,23,25-26,30H,5-14,18H2,1-4H3,(H,29,32)/t23-,25-,26-,28+/m1/s1
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593n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C beta


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50099067
PNG
(CHEMBL173348 | Dodecanoic acid (3S,3aR,8S,8aS)-3-h...)
Show SMILES CCCCCCCCCCCC(=O)Oc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@](C)(C(C)C)c2c1
Show InChI InChI=1S/C28H43NO4/c1-5-6-7-8-9-10-11-12-13-14-24(31)33-20-15-16-21-22(17-20)28(4,19(2)3)26-25(21)23(18-30)29-27(26)32/h15-17,19,23,25-26,30H,5-14,18H2,1-4H3,(H,29,32)/t23-,25-,26-,28-/m1/s1
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674n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C alpha


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
PKC alpha and beta-2


(Homo sapiens (Human))
BDBM50099065
PNG
((3S,3aR,8R,8aS)-6-Dec-1-ynyl-3-hydroxymethyl-8-iso...)
Show SMILES CCCCCCCCC#Cc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@@](C)(C(C)C)c2c1
Show InChI InChI=1S/C26H37NO2/c1-5-6-7-8-9-10-11-12-13-19-14-15-20-21(16-19)26(4,18(2)3)24-23(20)22(17-28)27-25(24)29/h14-16,18,22-24,28H,5-11,17H2,1-4H3,(H,27,29)/t22-,23-,24-,26+/m1/s1
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701n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C beta


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
PKC alpha and beta-2


(Homo sapiens (Human))
BDBM50099067
PNG
(CHEMBL173348 | Dodecanoic acid (3S,3aR,8S,8aS)-3-h...)
Show SMILES CCCCCCCCCCCC(=O)Oc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@](C)(C(C)C)c2c1
Show InChI InChI=1S/C28H43NO4/c1-5-6-7-8-9-10-11-12-13-14-24(31)33-20-15-16-21-22(17-20)28(4,19(2)3)26-25(21)23(18-30)29-27(26)32/h15-17,19,23,25-26,30H,5-14,18H2,1-4H3,(H,29,32)/t23-,25-,26-,28-/m1/s1
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1.05E+3n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C beta


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50099064
PNG
(CHEMBL368720 | Dodecanoic acid (3S,3aR,8R,8aS)-3-h...)
Show SMILES CCCCCCCCCCCC(=O)Oc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@@](C)(C(C)C)c2c1
Show InChI InChI=1S/C28H43NO4/c1-5-6-7-8-9-10-11-12-13-14-24(31)33-20-15-16-21-22(17-20)28(4,19(2)3)26-25(21)23(18-30)29-27(26)32/h15-17,19,23,25-26,30H,5-14,18H2,1-4H3,(H,29,32)/t23-,25-,26-,28+/m1/s1
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1.37E+3n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C delta


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50099065
PNG
((3S,3aR,8R,8aS)-6-Dec-1-ynyl-3-hydroxymethyl-8-iso...)
Show SMILES CCCCCCCCC#Cc1ccc2[C@@H]3[C@@H](CO)NC(=O)[C@@H]3[C@@](C)(C(C)C)c2c1
Show InChI InChI=1S/C26H37NO2/c1-5-6-7-8-9-10-11-12-13-19-14-15-20-21(16-19)26(4,18(2)3)24-23(20)22(17-28)27-25(24)29/h14-16,18,22-24,28H,5-11,17H2,1-4H3,(H,27,29)/t22-,23-,24-,26+/m1/s1
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1.63E+3n/an/an/an/an/an/an/an/a



Georgetotwn University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-phorbol 12,13-dibutyrate (PDBu) binding to human recombinant protein kinase C delta


Bioorg Med Chem Lett 11: 955-9 (2001)


BindingDB Entry DOI: 10.7270/Q2D799PV
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%