Found 105 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421512
(CHEMBL95523)Show InChI InChI=1S/C12H16N4O/c1-13-12(17)9-4-2-3-5-10(9)16-8-11-14-6-7-15-11/h2-5,16H,6-8H2,1H3,(H,13,17)(H,14,15) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1D adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421512
(CHEMBL95523)Show InChI InChI=1S/C12H16N4O/c1-13-12(17)9-4-2-3-5-10(9)16-8-11-14-6-7-15-11/h2-5,16H,6-8H2,1H3,(H,13,17)(H,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 214 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against Alpha-1A adrenergic receptor in human |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421516
(CHEMBL319553)Show InChI InChI=1S/C14H19N3O2/c1-10(2)19-14(18)11-5-3-4-6-12(11)17-9-13-15-7-8-16-13/h3-6,10,17H,7-9H2,1-2H3,(H,15,16) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 224 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against Alpha-1A adrenergic receptor in human |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421515
(CHEMBL320419)Show InChI InChI=1S/C15H22N4O/c1-2-3-8-18-15(20)12-6-4-5-7-13(12)19-11-14-16-9-10-17-14/h4-7,19H,2-3,8-11H2,1H3,(H,16,17)(H,18,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 468 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against Alpha-1A adrenergic receptor in human |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421512
(CHEMBL95523)Show InChI InChI=1S/C12H16N4O/c1-13-12(17)9-4-2-3-5-10(9)16-8-11-14-6-7-15-11/h2-5,16H,6-8H2,1H3,(H,13,17)(H,14,15) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 692 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1B adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421513
(CHEMBL421011)Show InChI InChI=1S/C15H22N4O/c1-3-19(4-2)15(20)12-7-5-6-8-13(12)18-11-14-16-9-10-17-14/h5-8,18H,3-4,9-11H2,1-2H3,(H,16,17) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 851 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against Alpha-1A adrenergic receptor in human |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421514
(CHEMBL97044)Show InChI InChI=1S/C14H18N4O/c19-14(18-10-5-6-10)11-3-1-2-4-12(11)17-9-13-15-7-8-16-13/h1-4,10,17H,5-9H2,(H,15,16)(H,18,19) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against Alpha-1A adrenergic receptor in human |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421515
(CHEMBL320419)Show InChI InChI=1S/C15H22N4O/c1-2-3-8-18-15(20)12-6-4-5-7-13(12)19-11-14-16-9-10-17-14/h4-7,19H,2-3,8-11H2,1H3,(H,16,17)(H,18,20) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1D adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421514
(CHEMBL97044)Show InChI InChI=1S/C14H18N4O/c19-14(18-10-5-6-10)11-3-1-2-4-12(11)17-9-13-15-7-8-16-13/h1-4,10,17H,5-9H2,(H,15,16)(H,18,19) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1D adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421516
(CHEMBL319553)Show InChI InChI=1S/C14H19N3O2/c1-10(2)19-14(18)11-5-3-4-6-12(11)17-9-13-15-7-8-16-13/h3-6,10,17H,7-9H2,1-2H3,(H,15,16) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1B adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421515
(CHEMBL320419)Show InChI InChI=1S/C15H22N4O/c1-2-3-8-18-15(20)12-6-4-5-7-13(12)19-11-14-16-9-10-17-14/h4-7,19H,2-3,8-11H2,1H3,(H,16,17)(H,18,20) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1B adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421516
(CHEMBL319553)Show InChI InChI=1S/C14H19N3O2/c1-10(2)19-14(18)11-5-3-4-6-12(11)17-9-13-15-7-8-16-13/h3-6,10,17H,7-9H2,1-2H3,(H,15,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1D adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421517
(CHEMBL450018)Show InChI InChI=1S/C14H20N4O/c1-3-18(2)14(19)11-6-4-5-7-12(11)17-10-13-15-8-9-16-13/h4-7,17H,3,8-10H2,1-2H3,(H,15,16) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against Alpha-1A adrenergic receptor in human |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421514
(CHEMBL97044)Show InChI InChI=1S/C14H18N4O/c19-14(18-10-5-6-10)11-3-1-2-4-12(11)17-9-13-15-7-8-16-13/h1-4,10,17H,5-9H2,(H,15,16)(H,18,19) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1B adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421513
(CHEMBL421011)Show InChI InChI=1S/C15H22N4O/c1-3-19(4-2)15(20)12-7-5-6-8-13(12)18-11-14-16-9-10-17-14/h5-8,18H,3-4,9-11H2,1-2H3,(H,16,17) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1B adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421513
(CHEMBL421011)Show InChI InChI=1S/C15H22N4O/c1-3-19(4-2)15(20)12-7-5-6-8-13(12)18-11-14-16-9-10-17-14/h5-8,18H,3-4,9-11H2,1-2H3,(H,16,17) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1D adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421517
(CHEMBL450018)Show InChI InChI=1S/C14H20N4O/c1-3-18(2)14(19)11-6-4-5-7-12(11)17-10-13-15-8-9-16-13/h4-7,17H,3,8-10H2,1-2H3,(H,15,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1D adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421517
(CHEMBL450018)Show InChI InChI=1S/C14H20N4O/c1-3-18(2)14(19)11-6-4-5-7-12(11)17-10-13-15-8-9-16-13/h4-7,17H,3,8-10H2,1-2H3,(H,15,16) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Concentration required for 50% inhibition of binding against human Alpha-1B adrenergic receptor |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219159
(CHEMBL95565)Show InChI InChI=1S/C15H22N4O/c1-11(2)9-19-15(20)12-5-3-4-6-13(12)18-10-14-16-7-8-17-14/h3-6,11,18H,7-10H2,1-2H3,(H,16,17)(H,19,20) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219160
(CHEMBL96988)Show InChI InChI=1S/C15H20N4O/c20-15(19-11-4-3-5-11)12-6-1-2-7-13(12)18-10-14-16-8-9-17-14/h1-2,6-7,11,18H,3-5,8-10H2,(H,16,17)(H,19,20) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421515
(CHEMBL320419)Show InChI InChI=1S/C15H22N4O/c1-2-3-8-18-15(20)12-6-4-5-7-13(12)19-11-14-16-9-10-17-14/h4-7,19H,2-3,8-11H2,1H3,(H,16,17)(H,18,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50027060
(2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imi...)Show InChI InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 63 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219158
(CHEMBL320910)Show InChI InChI=1S/C16H22N4O/c21-16(20-12-5-1-2-6-12)13-7-3-4-8-14(13)19-11-15-17-9-10-18-15/h3-4,7-8,12,19H,1-2,5-6,9-11H2,(H,17,18)(H,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421513
(CHEMBL421011)Show InChI InChI=1S/C15H22N4O/c1-3-19(4-2)15(20)12-7-5-6-8-13(12)18-11-14-16-9-10-17-14/h5-8,18H,3-4,9-11H2,1-2H3,(H,16,17) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421516
(CHEMBL319553)Show InChI InChI=1S/C14H19N3O2/c1-10(2)19-14(18)11-5-3-4-6-12(11)17-9-13-15-7-8-16-13/h3-6,10,17H,7-9H2,1-2H3,(H,15,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219130
(CHEMBL95398)Show InChI InChI=1S/C15H21N3O2/c1-11(2)10-20-15(19)12-5-3-4-6-13(12)18-9-14-16-7-8-17-14/h3-6,11,18H,7-10H2,1-2H3,(H,16,17) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 79 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219162
(CHEMBL98921)Show InChI InChI=1S/C17H23N3O2/c21-17(22-13-6-2-1-3-7-13)14-8-4-5-9-15(14)20-12-16-18-10-11-19-16/h4-5,8-9,13,20H,1-3,6-7,10-12H2,(H,18,19) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219162
(CHEMBL98921)Show InChI InChI=1S/C17H23N3O2/c21-17(22-13-6-2-1-3-7-13)14-8-4-5-9-15(14)20-12-16-18-10-11-19-16/h4-5,8-9,13,20H,1-3,6-7,10-12H2,(H,18,19) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50001922
(2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...)Show InChI InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421516
(CHEMBL319553)Show InChI InChI=1S/C14H19N3O2/c1-10(2)19-14(18)11-5-3-4-6-12(11)17-9-13-15-7-8-16-13/h3-6,10,17H,7-9H2,1-2H3,(H,15,16) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421517
(CHEMBL450018)Show InChI InChI=1S/C14H20N4O/c1-3-18(2)14(19)11-6-4-5-7-12(11)17-10-13-15-8-9-16-13/h4-7,17H,3,8-10H2,1-2H3,(H,15,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 631 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219154
(CHEMBL100198)Show InChI InChI=1S/C13H18N4O/c1-17(2)13(18)10-5-3-4-6-11(10)16-9-12-14-7-8-15-12/h3-6,16H,7-9H2,1-2H3,(H,14,15) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219157
(CHEMBL329928)Show InChI InChI=1S/C13H17N3O2/c1-2-18-13(17)10-5-3-4-6-11(10)16-9-12-14-7-8-15-12/h3-6,16H,2,7-9H2,1H3,(H,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219157
(CHEMBL329928)Show InChI InChI=1S/C13H17N3O2/c1-2-18-13(17)10-5-3-4-6-11(10)16-9-12-14-7-8-15-12/h3-6,16H,2,7-9H2,1H3,(H,14,15) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 158 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219134
(CHEMBL95333)Show InChI InChI=1S/C16H22N4O/c21-16(20-10-4-1-5-11-20)13-6-2-3-7-14(13)19-12-15-17-8-9-18-15/h2-3,6-7,19H,1,4-5,8-12H2,(H,17,18) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 398 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219131
(CHEMBL99362)Show InChI InChI=1S/C13H18N4O/c1-2-14-13(18)10-5-3-4-6-11(10)17-9-12-15-7-8-16-12/h3-6,17H,2,7-9H2,1H3,(H,14,18)(H,15,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 79 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219159
(CHEMBL95565)Show InChI InChI=1S/C15H22N4O/c1-11(2)9-19-15(20)12-5-3-4-6-13(12)18-10-14-16-7-8-17-14/h3-6,11,18H,7-10H2,1-2H3,(H,16,17)(H,19,20) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219136
(CHEMBL99559)Show InChI InChI=1S/C15H21N3O2/c1-2-3-10-20-15(19)12-6-4-5-7-13(12)18-11-14-16-8-9-17-14/h4-7,18H,2-3,8-11H2,1H3,(H,16,17) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421516
(CHEMBL319553)Show InChI InChI=1S/C14H19N3O2/c1-10(2)19-14(18)11-5-3-4-6-12(11)17-9-13-15-7-8-16-13/h3-6,10,17H,7-9H2,1-2H3,(H,15,16) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219153
(CHEMBL414185)Show InChI InChI=1S/C12H15N3O2/c1-17-12(16)9-4-2-3-5-10(9)15-8-11-13-6-7-14-11/h2-5,15H,6-8H2,1H3,(H,13,14) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.398 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219131
(CHEMBL99362)Show InChI InChI=1S/C13H18N4O/c1-2-14-13(18)10-5-3-4-6-11(10)17-9-12-15-7-8-16-12/h3-6,17H,2,7-9H2,1H3,(H,14,18)(H,15,16) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219135
(CHEMBL98243)Show InChI InChI=1S/C15H21N3O2/c1-15(2,3)20-14(19)11-6-4-5-7-12(11)18-10-13-16-8-9-17-13/h4-7,18H,8-10H2,1-3H3,(H,16,17) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 63 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219129
(CHEMBL432192)Show InChI InChI=1S/C15H22N4O/c1-3-11(2)19-15(20)12-6-4-5-7-13(12)18-10-14-16-8-9-17-14/h4-7,11,18H,3,8-10H2,1-2H3,(H,16,17)(H,19,20) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219131
(CHEMBL99362)Show InChI InChI=1S/C13H18N4O/c1-2-14-13(18)10-5-3-4-6-11(10)17-9-12-15-7-8-16-12/h3-6,17H,2,7-9H2,1H3,(H,14,18)(H,15,16) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219136
(CHEMBL99559)Show InChI InChI=1S/C15H21N3O2/c1-2-3-10-20-15(19)12-6-4-5-7-13(12)18-11-14-16-8-9-17-14/h4-7,18H,2-3,8-11H2,1H3,(H,16,17) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50001922
(2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...)Show InChI InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| DrugBank
PubMed
| n/a | n/a | n/a | n/a | 63 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219156
(CHEMBL97859)Show InChI InChI=1S/C15H21N3O2/c1-3-11(2)20-15(19)12-6-4-5-7-13(12)18-10-14-16-8-9-17-14/h4-7,11,18H,3,8-10H2,1-2H3,(H,16,17) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219152
(CHEMBL100383)Show InChI InChI=1S/C16H23N3O2/c1-3-12(4-2)21-16(20)13-7-5-6-8-14(13)19-11-15-17-9-10-18-15/h5-8,12,19H,3-4,9-11H2,1-2H3,(H,17,18) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219161
(CHEMBL329272)Show InChI InChI=1S/C16H21N3O2/c20-16(21-12-5-1-2-6-12)13-7-3-4-8-14(13)19-11-15-17-9-10-18-15/h3-4,7-8,12,19H,1-2,5-6,9-11H2,(H,17,18) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219160
(CHEMBL96988)Show InChI InChI=1S/C15H20N4O/c20-15(19-11-4-3-5-11)12-6-1-2-7-13(12)18-10-14-16-8-9-17-14/h1-2,6-7,11,18H,3-5,8-10H2,(H,16,17)(H,19,20) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219135
(CHEMBL98243)Show InChI InChI=1S/C15H21N3O2/c1-15(2,3)20-14(19)11-6-4-5-7-12(11)18-10-13-16-8-9-17-13/h4-7,18H,8-10H2,1-3H3,(H,16,17) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421512
(CHEMBL95523)Show InChI InChI=1S/C12H16N4O/c1-13-12(17)9-4-2-3-5-10(9)16-8-11-14-6-7-15-11/h2-5,16H,6-8H2,1H3,(H,13,17)(H,14,15) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219156
(CHEMBL97859)Show InChI InChI=1S/C15H21N3O2/c1-3-11(2)20-15(19)12-6-4-5-7-13(12)18-10-14-16-8-9-17-14/h4-7,11,18H,3,8-10H2,1-2H3,(H,16,17) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219158
(CHEMBL320910)Show InChI InChI=1S/C16H22N4O/c21-16(20-12-5-1-2-6-12)13-7-3-4-8-14(13)19-11-15-17-9-10-18-15/h3-4,7-8,12,19H,1-2,5-6,9-11H2,(H,17,18)(H,20,21) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219130
(CHEMBL95398)Show InChI InChI=1S/C15H21N3O2/c1-11(2)10-20-15(19)12-5-3-4-6-13(12)18-9-14-16-7-8-17-14/h3-6,11,18H,7-10H2,1-2H3,(H,16,17) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421514
(CHEMBL97044)Show InChI InChI=1S/C14H18N4O/c19-14(18-10-5-6-10)11-3-1-2-4-12(11)17-9-13-15-7-8-16-13/h1-4,10,17H,5-9H2,(H,15,16)(H,18,19) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219155
(CHEMBL98769)Show InChI InChI=1S/C16H24N4O/c1-3-11-20(4-2)16(21)13-7-5-6-8-14(13)19-12-15-17-9-10-18-15/h5-8,19H,3-4,9-12H2,1-2H3,(H,17,18) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219155
(CHEMBL98769)Show InChI InChI=1S/C16H24N4O/c1-3-11-20(4-2)16(21)13-7-5-6-8-14(13)19-12-15-17-9-10-18-15/h5-8,19H,3-4,9-12H2,1-2H3,(H,17,18) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421577
(CHEMBL318544)Show InChI InChI=1S/C14H20N4O/c1-2-7-17-14(19)11-5-3-4-6-12(11)18-10-13-15-8-9-16-13/h3-6,18H,2,7-10H2,1H3,(H,15,16)(H,17,19) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 79 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50027060
(2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imi...)Show InChI InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421515
(CHEMBL320419)Show InChI InChI=1S/C15H22N4O/c1-2-3-8-18-15(20)12-6-4-5-7-13(12)19-11-14-16-9-10-17-14/h4-7,19H,2-3,8-11H2,1H3,(H,16,17)(H,18,20) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421513
(CHEMBL421011)Show InChI InChI=1S/C15H22N4O/c1-3-19(4-2)15(20)12-7-5-6-8-13(12)18-11-14-16-9-10-17-14/h5-8,18H,3-4,9-11H2,1-2H3,(H,16,17) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219154
(CHEMBL100198)Show InChI InChI=1S/C13H18N4O/c1-17(2)13(18)10-5-3-4-6-11(10)16-9-12-14-7-8-15-12/h3-6,16H,7-9H2,1-2H3,(H,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219134
(CHEMBL95333)Show InChI InChI=1S/C16H22N4O/c21-16(20-10-4-1-5-11-20)13-6-2-3-7-14(13)19-12-15-17-8-9-18-15/h2-3,6-7,19H,1,4-5,8-12H2,(H,17,18) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 79 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421512
(CHEMBL95523)Show InChI InChI=1S/C12H16N4O/c1-13-12(17)9-4-2-3-5-10(9)16-8-11-14-6-7-15-11/h2-5,16H,6-8H2,1H3,(H,13,17)(H,14,15) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219161
(CHEMBL329272)Show InChI InChI=1S/C16H21N3O2/c20-16(21-12-5-1-2-6-12)13-7-3-4-8-14(13)19-11-15-17-9-10-18-15/h3-4,7-8,12,19H,1-2,5-6,9-11H2,(H,17,18) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421512
(CHEMBL95523)Show InChI InChI=1S/C12H16N4O/c1-13-12(17)9-4-2-3-5-10(9)16-8-11-14-6-7-15-11/h2-5,16H,6-8H2,1H3,(H,13,17)(H,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219157
(CHEMBL329928)Show InChI InChI=1S/C13H17N3O2/c1-2-18-13(17)10-5-3-4-6-11(10)16-9-12-14-7-8-15-12/h3-6,16H,2,7-9H2,1H3,(H,14,15) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 63 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219153
(CHEMBL414185)Show InChI InChI=1S/C12H15N3O2/c1-17-12(16)9-4-2-3-5-10(9)15-8-11-13-6-7-14-11/h2-5,15H,6-8H2,1H3,(H,13,14) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.794 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)Show InChI InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
KEGG
PC cid
PC sid
PDB
UniChem
Similars
| DrugBank
PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50421517
(CHEMBL450018)Show InChI InChI=1S/C14H20N4O/c1-3-18(2)14(19)11-6-4-5-7-12(11)17-10-13-15-8-9-16-13/h4-7,17H,3,8-10H2,1-2H3,(H,15,16) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219158
(CHEMBL320910)Show InChI InChI=1S/C16H22N4O/c21-16(20-12-5-1-2-6-12)13-7-3-4-8-14(13)19-11-15-17-9-10-18-15/h3-4,7-8,12,19H,1-2,5-6,9-11H2,(H,17,18)(H,20,21) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219150
(CHEMBL98016)Show InChI InChI=1S/C14H20N4O/c1-10(2)18-14(19)11-5-3-4-6-12(11)17-9-13-15-7-8-16-13/h3-6,10,17H,7-9H2,1-2H3,(H,15,16)(H,18,19) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421577
(CHEMBL318544)Show InChI InChI=1S/C14H20N4O/c1-2-7-17-14(19)11-5-3-4-6-12(11)18-10-13-15-8-9-16-13/h3-6,18H,2,7-10H2,1H3,(H,15,16)(H,17,19) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 158 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219151
(CHEMBL95245)Show InChI InChI=1S/C15H20N4O/c20-15(19-9-3-4-10-19)12-5-1-2-6-13(12)18-11-14-16-7-8-17-14/h1-2,5-6,18H,3-4,7-11H2,(H,16,17) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219151
(CHEMBL95245)Show InChI InChI=1S/C15H20N4O/c20-15(19-9-3-4-10-19)12-5-1-2-6-13(12)18-11-14-16-7-8-17-14/h1-2,5-6,18H,3-4,7-11H2,(H,16,17) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 316 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219154
(CHEMBL100198)Show InChI InChI=1S/C13H18N4O/c1-17(2)13(18)10-5-3-4-6-11(10)16-9-12-14-7-8-15-12/h3-6,16H,7-9H2,1-2H3,(H,14,15) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 79 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219159
(CHEMBL95565)Show InChI InChI=1S/C15H22N4O/c1-11(2)9-19-15(20)12-5-3-4-6-13(12)18-10-14-16-7-8-17-14/h3-6,11,18H,7-10H2,1-2H3,(H,16,17)(H,19,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 79 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219129
(CHEMBL432192)Show InChI InChI=1S/C15H22N4O/c1-3-11(2)19-15(20)12-6-4-5-7-13(12)18-10-14-16-8-9-17-14/h4-7,11,18H,3,8-10H2,1-2H3,(H,16,17)(H,19,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219129
(CHEMBL432192)Show InChI InChI=1S/C15H22N4O/c1-3-11(2)19-15(20)12-6-4-5-7-13(12)18-10-14-16-8-9-17-14/h4-7,11,18H,3,8-10H2,1-2H3,(H,16,17)(H,19,20) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)Show InChI InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
KEGG
PC cid
PC sid
PDB
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219153
(CHEMBL414185)Show InChI InChI=1S/C12H15N3O2/c1-17-12(16)9-4-2-3-5-10(9)15-8-11-13-6-7-14-11/h2-5,15H,6-8H2,1H3,(H,13,14) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.501 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219150
(CHEMBL98016)Show InChI InChI=1S/C14H20N4O/c1-10(2)18-14(19)11-5-3-4-6-12(11)17-9-13-15-7-8-16-13/h3-6,10,17H,7-9H2,1-2H3,(H,15,16)(H,18,19) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 316 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50001922
(2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...)Show InChI InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421515
(CHEMBL320419)Show InChI InChI=1S/C15H22N4O/c1-2-3-8-18-15(20)12-6-4-5-7-13(12)19-11-14-16-9-10-17-14/h4-7,19H,2-3,8-11H2,1H3,(H,16,17)(H,18,20) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)Show InChI InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
KEGG
PC cid
PC sid
PDB
UniChem
Similars
| DrugBank
PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219160
(CHEMBL96988)Show InChI InChI=1S/C15H20N4O/c20-15(19-11-4-3-5-11)12-6-1-2-7-13(12)18-10-14-16-8-9-17-14/h1-2,6-7,11,18H,3-5,8-10H2,(H,16,17)(H,19,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421514
(CHEMBL97044)Show InChI InChI=1S/C14H18N4O/c19-14(18-10-5-6-10)11-3-1-2-4-12(11)17-9-13-15-7-8-16-13/h1-4,10,17H,5-9H2,(H,15,16)(H,18,19) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50421514
(CHEMBL97044)Show InChI InChI=1S/C14H18N4O/c19-14(18-10-5-6-10)11-3-1-2-4-12(11)17-9-13-15-7-8-16-13/h1-4,10,17H,5-9H2,(H,15,16)(H,18,19) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421577
(CHEMBL318544)Show InChI InChI=1S/C14H20N4O/c1-2-7-17-14(19)11-5-3-4-6-12(11)18-10-13-15-8-9-16-13/h3-6,18H,2,7-10H2,1H3,(H,15,16)(H,17,19) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219130
(CHEMBL95398)Show InChI InChI=1S/C15H21N3O2/c1-11(2)10-20-15(19)12-5-3-4-6-13(12)18-9-14-16-7-8-17-14/h3-6,11,18H,7-10H2,1-2H3,(H,16,17) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219135
(CHEMBL98243)Show InChI InChI=1S/C15H21N3O2/c1-15(2,3)20-14(19)11-6-4-5-7-12(11)18-10-13-16-8-9-17-13/h4-7,18H,8-10H2,1-3H3,(H,16,17) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219151
(CHEMBL95245)Show InChI InChI=1S/C15H20N4O/c20-15(19-9-3-4-10-19)12-5-1-2-6-13(12)18-11-14-16-7-8-17-14/h1-2,5-6,18H,3-4,7-11H2,(H,16,17) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421517
(CHEMBL450018)Show InChI InChI=1S/C14H20N4O/c1-3-18(2)14(19)11-6-4-5-7-12(11)17-10-13-15-8-9-16-13/h4-7,17H,3,8-10H2,1-2H3,(H,15,16) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219152
(CHEMBL100383)Show InChI InChI=1S/C16H23N3O2/c1-3-12(4-2)21-16(20)13-7-5-6-8-14(13)19-11-15-17-9-10-18-15/h5-8,12,19H,3-4,9-11H2,1-2H3,(H,17,18) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219134
(CHEMBL95333)Show InChI InChI=1S/C16H22N4O/c21-16(20-10-4-1-5-11-20)13-6-2-3-7-14(13)19-12-15-17-8-9-18-15/h2-3,6-7,19H,1,4-5,8-12H2,(H,17,18) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 398 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219161
(CHEMBL329272)Show InChI InChI=1S/C16H21N3O2/c20-16(21-12-5-1-2-6-12)13-7-3-4-8-14(13)19-11-15-17-9-10-18-15/h3-4,7-8,12,19H,1-2,5-6,9-11H2,(H,17,18) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50027060
(2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imi...)Show InChI InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50421513
(CHEMBL421011)Show InChI InChI=1S/C15H22N4O/c1-3-19(4-2)15(20)12-7-5-6-8-13(12)18-11-14-16-9-10-17-14/h5-8,18H,3-4,9-11H2,1-2H3,(H,16,17) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219156
(CHEMBL97859)Show InChI InChI=1S/C15H21N3O2/c1-3-11(2)20-15(19)12-6-4-5-7-13(12)18-10-14-16-8-9-17-14/h4-7,11,18H,3,8-10H2,1-2H3,(H,16,17) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219150
(CHEMBL98016)Show InChI InChI=1S/C14H20N4O/c1-10(2)18-14(19)11-5-3-4-6-12(11)17-9-13-15-7-8-16-13/h3-6,10,17H,7-9H2,1-2H3,(H,15,16)(H,18,19) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50219152
(CHEMBL100383)Show InChI InChI=1S/C16H23N3O2/c1-3-12(4-2)21-16(20)13-7-5-6-8-14(13)19-11-15-17-9-10-18-15/h5-8,12,19H,3-4,9-11H2,1-2H3,(H,17,18) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219162
(CHEMBL98921)Show InChI InChI=1S/C17H23N3O2/c21-17(22-13-6-2-1-3-7-13)14-8-4-5-9-15(14)20-12-16-18-10-11-19-16/h4-5,8-9,13,20H,1-3,6-7,10-12H2,(H,18,19) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | <5.01E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50219136
(CHEMBL99559)Show InChI InChI=1S/C15H21N3O2/c1-2-3-10-20-15(19)12-6-4-5-7-13(12)18-11-14-16-8-9-17-14/h4-7,18H,2-3,8-11H2,1H3,(H,16,17) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50219155
(CHEMBL98769)Show InChI InChI=1S/C16H24N4O/c1-3-11-20(4-2)16(21)13-7-5-6-8-14(13)19-12-15-17-9-10-18-15/h5-8,19H,3-4,9-12H2,1-2H3,(H,17,18) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. |
Bioorg Med Chem Lett 11: 2871-4 (2001)
BindingDB Entry DOI: 10.7270/Q2CC1201 |
More data for this
Ligand-Target Pair | |
Search and Browse
