Affinity Data by PubMed id=11960499

PubMed code 11960499

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Albumin (Homo sapiens (Human))	BDBM50112213 (1-Azido-2-bromo-2-chloro-1,1-difluoro-ethane \| CHE...) Show SMILES FC(F)(N=[N+]=[N-])C(Cl)Br Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Health System Curated by ChEMBL					Assay Description Inhibitory concentration of the compound bound to tryptophan containing region of Serum albumin in fluorescence quenching				J Med Chem 45: 1879-86 (2002) BindingDB Entry DOI: 10.7270/Q2QF8S79
University of Pennsylvania Health System Curated by ChEMBL					More data for this Ligand-Target Pair
Albumin (Homo sapiens (Human))	BDBM50112209 (3-Bromo-3-trifluoromethyl-3H-diazirine \| CHEMBL298...) Show SMILES FC(F)(F)C1(Br)N=N1 \|c:6\| Show InChI InChI=1S/C2BrF3N2/c3-1(7-8-1)2(4,5)6	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Health System Curated by ChEMBL					Assay Description Inhibitory concentration of the compound bound to tryptophan containing region of Serum albumin in fluorescence quenching				J Med Chem 45: 1879-86 (2002) BindingDB Entry DOI: 10.7270/Q2QF8S79
University of Pennsylvania Health System Curated by ChEMBL					More data for this Ligand-Target Pair
Albumin (Homo sapiens (Human))	BDBM50112214 (3-Bromo-3-(2-chloro-1,1,2-trifluoro-ethyl)-3H-diaz...) Show SMILES FC(Cl)C(F)(F)C1(Br)N=N1 \|c:8\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Health System Curated by ChEMBL					Assay Description Inhibitory concentration of the compound bound to tryptophan containing region of Serum albumin in fluorescence quenching				J Med Chem 45: 1879-86 (2002) BindingDB Entry DOI: 10.7270/Q2QF8S79
University of Pennsylvania Health System Curated by ChEMBL					More data for this Ligand-Target Pair
Albumin (Homo sapiens (Human))	BDBM50112210 (3-(2-Bromo-2-chloro-1,1-difluoro-ethyl)-3H-diaziri...) Show SMILES FC(F)(C(Cl)Br)C1N=N1 \|c:7\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Health System Curated by ChEMBL					Assay Description Inhibitory concentration of the compound bound to tryptophan containing region of Serum albumin in fluorescence quenching				J Med Chem 45: 1879-86 (2002) BindingDB Entry DOI: 10.7270/Q2QF8S79
University of Pennsylvania Health System Curated by ChEMBL					More data for this Ligand-Target Pair
Albumin (Homo sapiens (Human))	BDBM50112215 (2-Diazo-1,1,1-trifluoro-ethane \| CHEMBL54683) Show SMILES FC(F)(F)[CH-][N+]#N Show InChI InChI=1S/C2HF3N2/c3-2(4,5)1-7-6/h1H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.20E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Health System Curated by ChEMBL					Assay Description Inhibitory concentration of the compound bound to tryptophan containing region of Serum albumin in fluorescence quenching				J Med Chem 45: 1879-86 (2002) BindingDB Entry DOI: 10.7270/Q2QF8S79
University of Pennsylvania Health System Curated by ChEMBL					More data for this Ligand-Target Pair
Albumin (Homo sapiens (Human))	BDBM50112211 (3-(2-Chloro-1,1,2-trifluoro-ethyl)-3-fluoro-3H-dia...) Show SMILES FC(Cl)C(F)(F)C1(F)N=N1 \|c:8\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.20E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Health System Curated by ChEMBL					Assay Description Inhibitory concentration of the compound bound to tryptophan containing region of Serum albumin in fluorescence quenching				J Med Chem 45: 1879-86 (2002) BindingDB Entry DOI: 10.7270/Q2QF8S79
University of Pennsylvania Health System Curated by ChEMBL					More data for this Ligand-Target Pair
Albumin (Homo sapiens (Human))	BDBM50112212 (1,1,1-trifluoro-2-bromo-2-chloroethane \| 1,1,1-tri...) Show SMILES FC(F)(F)C(Cl)Br Show InChI InChI=1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents	DrugBank PDB PubMed	n/a	n/a	2.90E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Health System Curated by ChEMBL					Assay Description Inhibitory concentration of the compound bound to tryptophan containing region of Serum albumin in fluorescence quenching				J Med Chem 45: 1879-86 (2002) BindingDB Entry DOI: 10.7270/Q2QF8S79
University of Pennsylvania Health System Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%