Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM20164 ((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2S)-3,3-di...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 95 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM20167 (2-(3-{3-[(2,2-diphenylethyl)[(4-methoxyphenyl)meth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 860 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM20170 (2-(3-{3-[(2,2-diphenylethyl)[(2-fluoro-4-methoxyph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 190 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM19992 (2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 125 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM19993 (CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM20171 (2-(3-{3-[(2,2-diphenylethyl)({[3-(trifluoromethyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 85 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM20166 (2-(3-{3-[(2,2-diphenylethyl)[(4-methoxyphenyl)meth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 260 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM20169 (2-(3-{3-[(2,2-diphenylethyl)[(3-fluoro-4-methoxyph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 250 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM20172 (2-(3-{3-[(2,2-diphenylethyl)({[4-fluoro-3-(trifluo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 85 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM20173 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 45 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM20168 (2-[3-(3-{[(2,4-dimethoxyphenyl)methyl](2,2-dipheny...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 660 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM20165 (3-(3-{[(3,4-dimethoxyphenyl)methyl](2,2-diphenylet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 260 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair |