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PubMed code 15006385

Compile data set for download or QSAR
Found 36 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50224040
PNG
(CHEMBL286441)
Show SMILES CCCCCN1C(=O)C(CC(=O)NO)Sc2ccccc12
Show InChI InChI=1S/C15H20N2O3S/c1-2-3-6-9-17-11-7-4-5-8-12(11)21-13(15(17)19)10-14(18)16-20/h4-5,7-8,13,20H,2-3,6,9-10H2,1H3,(H,16,18)
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n/an/a<5n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50224041
PNG
(CHEMBL34538)
Show SMILES CC(C)CCCN1C(=O)C(CC(=O)NO)Sc2ccccc12
Show InChI InChI=1S/C16H22N2O3S/c1-11(2)6-5-9-18-12-7-3-4-8-13(12)22-14(16(18)20)10-15(19)17-21/h3-4,7-8,11,14,21H,5-6,9-10H2,1-2H3,(H,17,19)
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n/an/a<5n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50224039
PNG
(CHEMBL36605)
Show SMILES ONC(=O)CC1Sc2ccccc2N(CCc2ccccc2)C1=O
Show InChI InChI=1S/C18H18N2O3S/c21-17(19-23)12-16-18(22)20(11-10-13-6-2-1-3-7-13)14-8-4-5-9-15(14)24-16/h1-9,16,23H,10-12H2,(H,19,21)
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n/an/a<5n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50089194
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Show SMILES CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO
Show InChI InChI=1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)/t14-,15+,17+/m1/s1
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n/an/a<5n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50224043
PNG
(CHEMBL36229)
Show SMILES COCCN1C(=O)C(CC(=O)NO)Sc2ccccc12
Show InChI InChI=1S/C13H16N2O4S/c1-19-7-6-15-9-4-2-3-5-10(9)20-11(13(15)17)8-12(16)14-18/h2-5,11,18H,6-8H2,1H3,(H,14,16)
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n/an/a<5n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50224038
PNG
(CHEMBL38016)
Show SMILES ONC(=O)CC1Sc2ccccc2N(CCC2OCCO2)C1=O
Show InChI InChI=1S/C15H18N2O5S/c18-13(16-20)9-12-15(19)17(6-5-14-21-7-8-22-14)10-3-1-2-4-11(10)23-12/h1-4,12,14,20H,5-9H2,(H,16,18)
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n/an/a<5n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50224042
PNG
(CHEMBL36140)
Show SMILES CC(C)CCN1C(=O)C(CC(=O)NO)Sc2ccccc12
Show InChI InChI=1S/C15H20N2O3S/c1-10(2)7-8-17-11-5-3-4-6-12(11)21-13(15(17)19)9-14(18)16-20/h3-6,10,13,20H,7-9H2,1-2H3,(H,16,18)
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n/an/a<5n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141373
PNG
(CHEMBL37719 | N-Hydroxy-2-(3-oxo-3,4-dihydro-2H-be...)
Show SMILES ONC(=O)CC1Sc2ccccc2NC1=O
Show InChI InChI=1S/C10H10N2O3S/c13-9(12-15)5-8-10(14)11-6-3-1-2-4-7(6)16-8/h1-4,8,15H,5H2,(H,11,14)(H,12,13)
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n/an/a<5n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141359
PNG
(CHEMBL285938 | N-Hydroxy-N-(3-oxo-3,4-dihydro-2H-b...)
Show SMILES ON(CC1Sc2ccccc2NC1=O)C=O
Show InChI InChI=1S/C10H10N2O3S/c13-6-12(15)5-9-10(14)11-7-3-1-2-4-8(7)16-9/h1-4,6,9,15H,5H2,(H,11,14)
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n/an/a 10n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141360
PNG
(2-(4-Benzyl-3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin...)
Show SMILES ONC(=O)CC1Sc2ccccc2N(Cc2ccccc2)C1=O
Show InChI InChI=1S/C17H16N2O3S/c20-16(18-22)10-15-17(21)19(11-12-6-2-1-3-7-12)13-8-4-5-9-14(13)23-15/h1-9,15,22H,10-11H2,(H,18,20)
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n/an/a 12n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141370
PNG
(CHEMBL34024 | N-Hydroxy-2-[3-oxo-4-(tetrahydro-pyr...)
Show SMILES ONC(=O)CC1Sc2ccccc2N(CC2CCCCO2)C1=O
Show InChI InChI=1S/C16H20N2O4S/c19-15(17-21)9-14-16(20)18(10-11-5-3-4-8-22-11)12-6-1-2-7-13(12)23-14/h1-2,6-7,11,14,21H,3-5,8-10H2,(H,17,19)
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n/an/a 18n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141369
PNG
(2-(4-Cyclopropylmethyl-3-oxo-3,4-dihydro-2H-benzo[...)
Show SMILES ONC(=O)CC1Sc2ccccc2N(CC2CC2)C1=O
Show InChI InChI=1S/C14H16N2O3S/c17-13(15-19)7-12-14(18)16(8-9-5-6-9)10-3-1-2-4-11(10)20-12/h1-4,9,12,19H,5-8H2,(H,15,17)
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n/an/a 29n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141363
PNG
(CHEMBL287497 | N-Hydroxy-2-(4-methyl-3-oxo-3,4-dih...)
Show SMILES CN1C(=O)C(CC(=O)NO)Sc2ccccc12
Show InChI InChI=1S/C11H12N2O3S/c1-13-7-4-2-3-5-8(7)17-9(11(13)15)6-10(14)12-16/h2-5,9,16H,6H2,1H3,(H,12,14)
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n/an/a 37n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141365
PNG
(2-(4-Cyclobutylmethyl-3-oxo-3,4-dihydro-2H-benzo[1...)
Show SMILES ONC(=O)CC1Sc2ccccc2N(CC2CCC2)C1=O
Show InChI InChI=1S/C15H18N2O3S/c18-14(16-20)8-13-15(19)17(9-10-4-3-5-10)11-6-1-2-7-12(11)21-13/h1-2,6-7,10,13,20H,3-5,8-9H2,(H,16,18)
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n/an/a 41n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141366
PNG
(2-(2-Hydroxycarbamoylmethyl-3-oxo-2,3-dihydro-benz...)
Show SMILES CC(N1C(=O)C(CC(=O)NO)Sc2ccccc12)C(N)=O
Show InChI InChI=1S/C13H15N3O4S/c1-7(12(14)18)16-8-4-2-3-5-9(8)21-10(13(16)19)6-11(17)15-20/h2-5,7,10,20H,6H2,1H3,(H2,14,18)(H,15,17)
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n/an/a 44n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141385
PNG
(2-[4-(3,3-Dimethyl-2-oxo-butyl)-3-oxo-3,4-dihydro-...)
Show SMILES CC(C)(C)C(=O)CN1C(=O)C(CC(=O)NO)Sc2ccccc12
Show InChI InChI=1S/C16H20N2O4S/c1-16(2,3)13(19)9-18-10-6-4-5-7-11(10)23-12(15(18)21)8-14(20)17-22/h4-7,12,22H,8-9H2,1-3H3,(H,17,20)
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n/an/a 50n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141390
PNG
(2-[4-(2-Cyclohexyl-ethyl)-3-oxo-3,4-dihydro-2H-ben...)
Show SMILES ONC(=O)CC1Sc2ccccc2N(CCC2CCCCC2)C1=O
Show InChI InChI=1S/C18H24N2O3S/c21-17(19-23)12-16-18(22)20(11-10-13-6-2-1-3-7-13)14-8-4-5-9-15(14)24-16/h4-5,8-9,13,16,23H,1-3,6-7,10-12H2,(H,19,21)
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n/an/a 57n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141374
PNG
(2-{4-[(2,5-Difluoro-phenylcarbamoyl)-methyl]-3-oxo...)
Show SMILES ONC(=O)CC1Sc2ccccc2N(CC(=O)Nc2cc(F)ccc2F)C1=O
Show InChI InChI=1S/C18H15F2N3O4S/c19-10-5-6-11(20)12(7-10)21-17(25)9-23-13-3-1-2-4-14(13)28-15(18(23)26)8-16(24)22-27/h1-7,15,27H,8-9H2,(H,21,25)(H,22,24)
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n/an/a 58n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141388
PNG
(CHEMBL34426 | N-Hydroxy-2-[1-(3-methyl-butyl)-2-ox...)
Show SMILES CC(C)CCN1C(=O)C(CC(=O)NO)Cc2ccccc12
Show InChI InChI=1S/C16H22N2O3/c1-11(2)7-8-18-14-6-4-3-5-12(14)9-13(16(18)20)10-15(19)17-21/h3-6,11,13,21H,7-10H2,1-2H3,(H,17,19)
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n/an/a 63n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141389
PNG
(CHEMBL37522 | N-Hydroxy-2-(2-oxo-1,2,3,4-tetrahydr...)
Show SMILES ONC(=O)CC1Cc2ccccc2NC1=O
Show InChI InChI=1S/C11H12N2O3/c14-10(13-16)6-8-5-7-3-1-2-4-9(7)12-11(8)15/h1-4,8,16H,5-6H2,(H,12,15)(H,13,14)
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n/an/a 73n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141368
PNG
(CHEMBL38164 | N-Methoxy-2-(3-oxo-3,4-dihydro-2H-be...)
Show SMILES CONC(=O)CC1Sc2ccccc2NC1=O
Show InChI InChI=1S/C11H12N2O3S/c1-16-13-10(14)6-9-11(15)12-7-4-2-3-5-8(7)17-9/h2-5,9H,6H2,1H3,(H,12,15)(H,13,14)
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n/an/a 74n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141376
PNG
(2-(8-Bromo-3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-...)
Show SMILES ONC(=O)CC1Sc2c(Br)cccc2NC1=O
Show InChI InChI=1S/C10H9BrN2O3S/c11-5-2-1-3-6-9(5)17-7(10(15)12-6)4-8(14)13-16/h1-3,7,16H,4H2,(H,12,15)(H,13,14)
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n/an/a 74n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141392
PNG
(2-(2-Hydroxycarbamoylmethyl-3-oxo-2,3-dihydro-benz...)
Show SMILES NC(=O)CN1C(=O)C(CC(=O)NO)Sc2ccccc12
Show InChI InChI=1S/C12H13N3O4S/c13-10(16)6-15-7-3-1-2-4-8(7)20-9(12(15)18)5-11(17)14-19/h1-4,9,19H,5-6H2,(H2,13,16)(H,14,17)
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n/an/a 168n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141364
PNG
(CHEMBL284794 | N-hydroxy-2-(2-oxo-2,3-dihydro-1H-1...)
Show SMILES ONC(=O)CC1C=Cc2ccccc2NC1=O |c:6|
Show InChI InChI=1S/C12H12N2O3/c15-11(14-17)7-9-6-5-8-3-1-2-4-10(8)13-12(9)16/h1-6,9,17H,7H2,(H,13,16)(H,14,15)
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n/an/a 169n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141387
PNG
(2-(1-Cyclopropylmethyl-2-oxo-1,2,3,4-tetrahydro-qu...)
Show SMILES ONC(=O)CC1Cc2ccccc2N(CC2CC2)C1=O
Show InChI InChI=1S/C15H18N2O3/c18-14(16-20)8-12-7-11-3-1-2-4-13(11)17(15(12)19)9-10-5-6-10/h1-4,10,12,20H,5-9H2,(H,16,18)
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n/an/a 175n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141382
PNG
(CHEMBL287247 | N-Benzyloxy-2-(3-oxo-3,4-dihydro-2H...)
Show SMILES O=C(CC1Sc2ccccc2NC1=O)NOCc1ccccc1
Show InChI InChI=1S/C17H16N2O3S/c20-16(19-22-11-12-6-2-1-3-7-12)10-15-17(21)18-13-8-4-5-9-14(13)23-15/h1-9,15H,10-11H2,(H,18,21)(H,19,20)
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n/an/a 230n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141362
PNG
(2-(4-Cyclohexylmethyl-3-oxo-3,4-dihydro-2H-benzo[1...)
Show SMILES ONC(=O)CC1Sc2ccccc2N(CC2CCCCC2)C1=O
Show InChI InChI=1S/C17H22N2O3S/c20-16(18-22)10-15-17(21)19(11-12-6-2-1-3-7-12)13-8-4-5-9-14(13)23-15/h4-5,8-9,12,15,22H,1-3,6-7,10-11H2,(H,18,20)
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n/an/a 302n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141379
PNG
((3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-acet...)
Show SMILES NNC(=O)CC1Sc2ccccc2NC1=O
Show InChI InChI=1S/C10H11N3O2S/c11-13-9(14)5-8-10(15)12-6-3-1-2-4-7(6)16-8/h1-4,8H,5,11H2,(H,12,15)(H,13,14)
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n/an/a 330n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141372
PNG
(CHEMBL417683 | N-Hydroxy-2-[3-oxo-4-(pyridin-2-ylc...)
Show SMILES ONC(=O)CC1Sc2ccccc2N(CC(=O)Nc2ccccn2)C1=O
Show InChI InChI=1S/C17H16N4O4S/c22-15(20-25)9-13-17(24)21(11-5-1-2-6-12(11)26-13)10-16(23)19-14-7-3-4-8-18-14/h1-8,13,25H,9-10H2,(H,20,22)(H,18,19,23)
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n/an/a 343n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141358
PNG
(CHEMBL285024 | N-Hydroxy-2-[3-oxo-4-(2-oxo-2-pyrro...)
Show SMILES ONC(=O)CC1Sc2ccccc2N(CC(=O)N2CCCC2)C1=O
Show InChI InChI=1S/C16H19N3O4S/c20-14(17-23)9-13-16(22)19(10-15(21)18-7-3-4-8-18)11-5-1-2-6-12(11)24-13/h1-2,5-6,13,23H,3-4,7-10H2,(H,17,20)
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n/an/a 397n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141371
PNG
(CHEMBL36126 | N-Hydroxy-N-(3-oxo-3,4-dihydro-2H-be...)
Show SMILES CC(=O)N(O)CC1Sc2ccccc2NC1=O
Show InChI InChI=1S/C11H12N2O3S/c1-7(14)13(16)6-10-11(15)12-8-4-2-3-5-9(8)17-10/h2-5,10,16H,6H2,1H3,(H,12,15)
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n/an/a 427n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141377
PNG
(2-(4-Cyanomethyl-3-oxo-3,4-dihydro-2H-benzo[1,4]th...)
Show SMILES ONC(=O)CC1Sc2ccccc2N(CC#N)C1=O
Show InChI InChI=1S/C12H11N3O3S/c13-5-6-15-8-3-1-2-4-9(8)19-10(12(15)17)7-11(16)14-18/h1-4,10,18H,6-7H2,(H,14,16)
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n/an/a 515n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141378
PNG
(CHEMBL38371 | N-Hydroxy-2-(1,1,3-trioxo-1,2,3,4-te...)
Show SMILES ONC(=O)CC1C(=O)Nc2ccccc2S1(=O)=O
Show InChI InChI=1S/C10H10N2O5S/c13-9(12-15)5-8-10(14)11-6-3-1-2-4-7(6)18(8,16)17/h1-4,8,15H,5H2,(H,11,14)(H,12,13)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141393
PNG
((3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-acet...)
Show SMILES OC(=O)CC1Sc2ccccc2NC1=O
Show InChI InChI=1S/C10H9NO3S/c12-9(13)5-8-10(14)11-6-3-1-2-4-7(6)15-8/h1-4,8H,5H2,(H,11,14)(H,12,13)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141375
PNG
(CHEMBL38162 | N-Methoxy-N-methyl-2-(3-oxo-3,4-dihy...)
Show SMILES CON(C)C(=O)CC1Sc2ccccc2NC1=O
Show InChI InChI=1S/C12H14N2O3S/c1-14(17-2)11(15)7-10-12(16)13-8-5-3-4-6-9(8)18-10/h3-6,10H,7H2,1-2H3,(H,13,16)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50141380
PNG
(2-Hydroxyaminomethyl-4H-benzo[1,4]thiazin-3-one | ...)
Show SMILES ONCC1Sc2ccccc2NC1=O
Show InChI InChI=1S/C9H10N2O2S/c12-9-8(5-10-13)14-7-4-2-1-3-6(7)11-9/h1-4,8,10,13H,5H2,(H,11,12)
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n/an/a>2.00E+3n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibitory activity towards Ni-peptide deformylase of Staphylococcus aureus

Bioorg Med Chem Lett 14: 1477-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.014
BindingDB Entry DOI: 10.7270/Q2MS3S6G
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%