Found 20 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150667
((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CSCC[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O6S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(34-15-17-8-6-5-7-9-17)22(35-18)24(31)29-20(25(32)33)12-13-36-4/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19+,20+,21+,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50366346
(CHEMBL1790477)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(=O)N[C@@H](CCSC)C(O)=O Show InChI InChI=1S/C19H36N4O5S2/c1-6-11(4)15(18(26)21-13(19(27)28)7-8-30-5)23-17(25)14(10(2)3)22-16(24)12(20)9-29/h10-15,29H,6-9,20H2,1-5H3,(H,21,26)(H,22,24)(H,23,25)(H,27,28)/t11-,12+,13+,14+,15+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150666
((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CS(=O)CC[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O7S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(35-15-17-8-6-5-7-9-17)22(36-18)24(31)29-20(25(32)33)12-13-39(4)34/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19+,20+,21+,22+,39?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150662
((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CC(C)C[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H43N3O6S2/c1-17(2)13-21(26(33)34)30-25(32)23-22(35-15-18-9-7-6-8-10-18)12-11-19(36-23)14-29-24(31)20(28)16-37-38-27(3,4)5/h6-10,17,19-23H,11-16,28H2,1-5H3,(H,29,31)(H,30,32)(H,33,34)/t19-,20+,21+,22+,23+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150665
((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CSCC[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O6S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(34-15-17-8-6-5-7-9-17)22(35-18)24(31)29-20(25(32)33)12-13-36-4/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19-,20-,21-,22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150665
((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CSCC[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O6S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(34-15-17-8-6-5-7-9-17)22(35-18)24(31)29-20(25(32)33)12-13-36-4/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19-,20-,21-,22-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150662
((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CC(C)C[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H43N3O6S2/c1-17(2)13-21(26(33)34)30-25(32)23-22(35-15-18-9-7-6-8-10-18)12-11-19(36-23)14-29-24(31)20(28)16-37-38-27(3,4)5/h6-10,17,19-23H,11-16,28H2,1-5H3,(H,29,31)(H,30,32)(H,33,34)/t19-,20+,21+,22+,23+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150664
((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CS(=O)CC[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O7S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(35-15-17-8-6-5-7-9-17)22(36-18)24(31)29-20(25(32)33)12-13-39(4)34/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19-,20-,21-,22-,39?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150663
((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CC(C)C[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H43N3O6S2/c1-17(2)13-21(26(33)34)30-25(32)23-22(35-15-18-9-7-6-8-10-18)12-11-19(36-23)14-29-24(31)20(28)16-37-38-27(3,4)5/h6-10,17,19-23H,11-16,28H2,1-5H3,(H,29,31)(H,30,32)(H,33,34)/t19-,20-,21-,22-,23-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.06E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150671
((S)-2-(1-{(2R,6R)-6-[((R)-2-Amino-3-tert-butyldisu...)Show SMILES CC(C)C[C@H](N=C(C)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CCC1O)C(O)=O |w:6.6| Show InChI InChI=1S/C21H39N3O5S2/c1-12(2)9-16(20(27)28)24-13(3)18-17(25)8-7-14(29-18)10-23-19(26)15(22)11-30-31-21(4,5)6/h12,14-18,25H,7-11,22H2,1-6H3,(H,23,26)(H,27,28)/t14-,15+,16+,17?,18-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.61E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150669
((S)-2-(1-{(2R,3S,6S)-6-[((R)-2-Amino-3-tert-butyld...)Show SMILES CC(C)C[C@H](N=C(C)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O |w:6.6| Show InChI InChI=1S/C28H45N3O5S2/c1-18(2)14-23(27(33)34)31-19(3)25-24(35-16-20-10-8-7-9-11-20)13-12-21(36-25)15-30-26(32)22(29)17-37-38-28(4,5)6/h7-11,18,21-25H,12-17,29H2,1-6H3,(H,30,32)(H,33,34)/t21-,22-,23-,24-,25+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150668
((S)-2-(1-{(2R,3S,6S)-6-[((R)-2-Amino-3-tert-butyld...)Show SMILES CSCC[C@H](N=C(C)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O |w:6.6| Show InChI InChI=1S/C27H43N3O5S3/c1-18(30-22(26(32)33)13-14-36-5)24-23(34-16-19-9-7-6-8-10-19)12-11-20(35-24)15-29-25(31)21(28)17-37-38-27(2,3)4/h6-10,20-24H,11-17,28H2,1-5H3,(H,29,31)(H,32,33)/t20-,21-,22-,23-,24+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.11E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150663
((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CC(C)C[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H43N3O6S2/c1-17(2)13-21(26(33)34)30-25(32)23-22(35-15-18-9-7-6-8-10-18)12-11-19(36-23)14-29-24(31)20(28)16-37-38-27(3,4)5/h6-10,17,19-23H,11-16,28H2,1-5H3,(H,29,31)(H,30,32)(H,33,34)/t19-,20-,21-,22-,23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150670
((S)-2-(1-{(2R,3S,6R)-6-[((R)-2-Amino-3-tert-butyld...)Show SMILES CC(C)C[C@H](N=C(C)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O |w:6.6| Show InChI InChI=1S/C28H45N3O5S2/c1-18(2)14-23(27(33)34)31-19(3)25-24(35-16-20-10-8-7-9-11-20)13-12-21(36-25)15-30-26(32)22(29)17-37-38-28(4,5)6/h7-11,18,21-25H,12-17,29H2,1-6H3,(H,30,32)(H,33,34)/t21-,22+,23+,24+,25-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.64E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150672
((S)-2-(1-{(2R,3S,6R)-6-[((R)-2-Amino-3-tert-butyld...)Show SMILES CSCC[C@H](N=C(C)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O |w:6.6| Show InChI InChI=1S/C27H43N3O5S3/c1-18(30-22(26(32)33)13-14-36-5)24-23(34-16-19-9-7-6-8-10-19)12-11-20(35-24)15-29-25(31)21(28)17-37-38-27(2,3)4/h6-10,20-24H,11-17,28H2,1-5H3,(H,29,31)(H,32,33)/t20-,21+,22+,23+,24-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150664
((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CS(=O)CC[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O7S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(35-15-17-8-6-5-7-9-17)22(36-18)24(31)29-20(25(32)33)12-13-39(4)34/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19-,20-,21-,22-,39?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150672
((S)-2-(1-{(2R,3S,6R)-6-[((R)-2-Amino-3-tert-butyld...)Show SMILES CSCC[C@H](N=C(C)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O |w:6.6| Show InChI InChI=1S/C27H43N3O5S3/c1-18(30-22(26(32)33)13-14-36-5)24-23(34-16-19-9-7-6-8-10-19)12-11-20(35-24)15-29-25(31)21(28)17-37-38-27(2,3)4/h6-10,20-24H,11-17,28H2,1-5H3,(H,29,31)(H,32,33)/t20-,21+,22+,23+,24-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150667
((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CSCC[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O6S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(34-15-17-8-6-5-7-9-17)22(35-18)24(31)29-20(25(32)33)12-13-36-4/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19+,20+,21+,22+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150671
((S)-2-(1-{(2R,6R)-6-[((R)-2-Amino-3-tert-butyldisu...)Show SMILES CC(C)C[C@H](N=C(C)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CCC1O)C(O)=O |w:6.6| Show InChI InChI=1S/C21H39N3O5S2/c1-12(2)9-16(20(27)28)24-13(3)18-17(25)8-7-14(29-18)10-23-19(26)15(22)11-30-31-21(4,5)6/h12,14-18,25H,7-11,22H2,1-6H3,(H,23,26)(H,27,28)/t14-,15+,16+,17?,18-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50150666
((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...)Show SMILES CS(=O)CC[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O7S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(35-15-17-8-6-5-7-9-17)22(36-18)24(31)29-20(25(32)33)12-13-39(4)34/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19+,20+,21+,22+,39?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I |
J Med Chem 47: 3920-3 (2004)
Article DOI: 10.1021/jm049927q
BindingDB Entry DOI: 10.7270/Q2FT8MT5 |
More data for this
Ligand-Target Pair | |
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