Found 46 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50110881
(4-(2-oxo-3-(4-(5-phenylpentylthio)phenoxy)propoxy)...)Show SMILES OC(=O)c1ccc(OCC(=O)COc2ccc(SCCCCCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C27H28O5S/c28-23(19-31-24-12-10-22(11-13-24)27(29)30)20-32-25-14-16-26(17-15-25)33-18-6-2-5-9-21-7-3-1-4-8-21/h1,3-4,7-8,10-17H,2,5-6,9,18-20H2,(H,29,30) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180066
(3-[4-[[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-...)Show SMILES Cc1c(CCS(=O)(=O)c2ccc(CCC(O)=O)cc2)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H30ClNO4S/c1-23-29(20-21-40(38,39)28-16-12-24(13-17-28)14-19-32(36)37)30-22-27(34)15-18-31(30)35(23)33(25-8-4-2-5-9-25)26-10-6-3-7-11-26/h2-13,15-18,22,33H,14,19-21H2,1H3,(H,36,37) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180081
(4-(2-(1-benzhydryl-5-chloro-2-methyl-1H-indol-3-yl...)Show SMILES Cc1c(CCS(=O)(=O)c2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO4S/c1-21-27(18-19-38(36,37)26-15-12-24(13-16-26)31(34)35)28-20-25(32)14-17-29(28)33(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180088
(4-[[2-[4,5-dichloro-1-(diphenylmethyl)-2-methyl-1H...)Show SMILES Cc1c(CCS(=O)(=O)c2ccc(cc2)C(O)=O)c2c(Cl)c(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H25Cl2NO4S/c1-20-25(18-19-39(37,38)24-14-12-23(13-15-24)31(35)36)28-27(17-16-26(32)29(28)33)34(20)30(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-17,30H,18-19H2,1H3,(H,35,36) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180070
(4-[[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-ind...)Show SMILES Cc1c(CCS(=O)c2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO3S/c1-21-27(18-19-37(36)26-15-12-24(13-16-26)31(34)35)28-20-25(32)14-17-29(28)33(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180097
(4-[[2-[1-(diphenylmethyl)-5-fluoro-2-methyl-1H-ind...)Show SMILES Cc1c(CCS(=O)(=O)c2ccc(cc2)C(O)=O)c2cc(F)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26FNO4S/c1-21-27(18-19-38(36,37)26-15-12-24(13-16-26)31(34)35)28-20-25(32)14-17-29(28)33(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180085
(4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indo...)Show SMILES Cc1c(CCOc2ccc(C(O)=O)c(F)c2)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H25ClFNO3/c1-20-25(16-17-37-24-13-14-26(31(35)36)28(33)19-24)27-18-23(32)12-15-29(27)34(20)30(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-15,18-19,30H,16-17H2,1H3,(H,35,36) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180087
(4-[[2-[1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]-...)Show SMILES Cc1c(CCS(=O)(=O)c2ccc(cc2)C(O)=O)c2ccccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H27NO4S/c1-22-27(20-21-37(35,36)26-18-16-25(17-19-26)31(33)34)28-14-8-9-15-29(28)32(22)30(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-19,30H,20-21H2,1H3,(H,33,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180059
(4-[4-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indo...)Show SMILES Cc1c(CCCCOc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H30ClNO3/c1-23-29(14-8-9-21-38-28-18-15-26(16-19-28)33(36)37)30-22-27(34)17-20-31(30)35(23)32(24-10-4-2-5-11-24)25-12-6-3-7-13-25/h2-7,10-13,15-20,22,32H,8-9,14,21H2,1H3,(H,36,37) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180079
(4-[2-[5-bromo-1-(diphenylmethyl)-2-methyl-1H-indol...)Show SMILES Cc1c(CCOc2ccc(cc2)C(O)=O)c2cc(Br)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26BrNO3/c1-21-27(18-19-36-26-15-12-24(13-16-26)31(34)35)28-20-25(32)14-17-29(28)33(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180065
(4-[[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-ind...)Show SMILES Cc1c(CCSc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO2S/c1-21-27(18-19-36-26-15-12-24(13-16-26)31(34)35)28-20-25(32)14-17-29(28)33(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180063
(4-[[2-[4-chloro-1-(diphenylmethyl)-2-methyl-1H-ind...)Show SMILES Cc1c(CCS(=O)(=O)c2ccc(cc2)C(O)=O)c2c(Cl)cccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO4S/c1-21-26(19-20-38(36,37)25-17-15-24(16-18-25)31(34)35)29-27(32)13-8-14-28(29)33(21)30(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-18,30H,19-20H2,1H3,(H,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180091
(4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indo...)Show SMILES Cc1c(CCCc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H28ClNO2/c1-22-28(14-8-9-23-15-17-26(18-16-23)32(35)36)29-21-27(33)19-20-30(29)34(22)31(24-10-4-2-5-11-24)25-12-6-3-7-13-25/h2-7,10-13,15-21,31H,8-9,14H2,1H3,(H,35,36) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180057
(4-(2-(1-benzhydryl-2-methyl-1H-indol-3-yl)ethoxy)b...)Show SMILES Cc1c(CCOc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO3/c1-21-27(18-19-36-26-15-12-24(13-16-26)31(34)35)28-20-25(32)14-17-29(28)33(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180062
(4-[[2-[1-(diphenylmethyl)-5-methoxy-2-methyl-1H-in...)Show SMILES COc1ccc2n(C(c3ccccc3)c3ccccc3)c(C)c(CCS(=O)(=O)c3ccc(cc3)C(O)=O)c2c1 Show InChI InChI=1S/C32H29NO5S/c1-22-28(19-20-39(36,37)27-16-13-25(14-17-27)32(34)35)29-21-26(38-2)15-18-30(29)33(22)31(23-9-5-3-6-10-23)24-11-7-4-8-12-24/h3-18,21,31H,19-20H2,1-2H3,(H,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180068
(3-[4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-i...)Show SMILES Cc1c(CCOc2ccc(CCC(O)=O)cc2)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H30ClNO3/c1-23-29(20-21-38-28-16-12-24(13-17-28)14-19-32(36)37)30-22-27(34)15-18-31(30)35(23)33(25-8-4-2-5-9-25)26-10-6-3-7-11-26/h2-13,15-18,22,33H,14,19-21H2,1H3,(H,36,37) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180058
(4-[[2-[5,6-dichloro-1-(diphenylmethyl)-2-methyl-1H...)Show SMILES Cc1c(CCS(=O)(=O)c2ccc(cc2)C(O)=O)c2cc(Cl)c(Cl)cc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H25Cl2NO4S/c1-20-25(16-17-39(37,38)24-14-12-23(13-15-24)31(35)36)26-18-27(32)28(33)19-29(26)34(20)30(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-15,18-19,30H,16-17H2,1H3,(H,35,36) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180072
(4-[[2-[6-chloro-1-(diphenylmethyl)-2-methyl-1H-ind...)Show SMILES Cc1c(CCS(=O)(=O)c2ccc(cc2)C(O)=O)c2ccc(Cl)cc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO4S/c1-21-27(18-19-38(36,37)26-15-12-24(13-16-26)31(34)35)28-17-14-25(32)20-29(28)33(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,35) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180071
(4-[2-[5-chloro-1-(diphenylmethyl)-1H-indol-3-yl]et...)Show SMILES OC(=O)c1ccc(OCCc2cn(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C30H24ClNO3/c31-25-13-16-28-27(19-25)24(17-18-35-26-14-11-23(12-15-26)30(33)34)20-32(28)29(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-16,19-20,29H,17-18H2,(H,33,34) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180084
(4-[2-[1-(diphenylmethyl)-2-methyl-5-nitro-1H-indol...)Show SMILES Cc1c(CCOc2ccc(cc2)C(O)=O)c2cc(ccc2n1C(c1ccccc1)c1ccccc1)[N+]([O-])=O Show InChI InChI=1S/C31H26N2O5/c1-21-27(18-19-38-26-15-12-24(13-16-26)31(34)35)28-20-25(33(36)37)14-17-29(28)32(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,35) | PDB
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| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180055
(4-[2-[6-chloro-1-(diphenylmethyl)-2-methyl-1H-indo...)Show SMILES Cc1c(CCOc2ccc(cc2)C(O)=O)c2ccc(Cl)cc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO3/c1-21-27(18-19-36-26-15-12-24(13-16-26)31(34)35)28-17-14-25(32)20-29(28)33(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,35) | PDB
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PC sid
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| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180086
(4-[[2-[7-chloro-1-(diphenylmethyl)-2-methyl-1H-ind...)Show SMILES Cc1c(CCS(=O)(=O)c2ccc(cc2)C(O)=O)c2cccc(Cl)c2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO4S/c1-21-26(19-20-38(36,37)25-17-15-24(16-18-25)31(34)35)27-13-8-14-28(32)30(27)33(21)29(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-18,29H,19-20H2,1H3,(H,34,35) | PDB
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| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180076
(2-chloro-4-[2-[5-chloro-1-(diphenylmethyl)-2-methy...)Show SMILES Cc1c(CCOc2ccc(C(O)=O)c(Cl)c2)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H25Cl2NO3/c1-20-25(16-17-37-24-13-14-26(31(35)36)28(33)19-24)27-18-23(32)12-15-29(27)34(20)30(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-15,18-19,30H,16-17H2,1H3,(H,35,36) | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180096
(4-[2-[5-amino-1-(diphenylmethyl)-2-methyl-1H-indol...)Show SMILES Cc1c(CCOc2ccc(cc2)C(O)=O)c2cc(N)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H28N2O3/c1-21-27(18-19-36-26-15-12-24(13-16-26)31(34)35)28-20-25(32)14-17-29(28)33(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19,32H2,1H3,(H,34,35) | PDB
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| Article
PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180056
(CHEMBL199500 | [4-[2-[5-chloro-1-(diphenylmethyl)-...)Show SMILES Cc1c(CCOc2ccc(CC(O)=O)cc2)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H28ClNO3/c1-22-28(18-19-37-27-15-12-23(13-16-27)20-31(35)36)29-21-26(33)14-17-30(29)34(22)32(24-8-4-2-5-9-24)25-10-6-3-7-11-25/h2-17,21,32H,18-20H2,1H3,(H,35,36) | PDB
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PC cid
PC sid
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180077
(3-chloro-4-[2-[5-chloro-1-(diphenylmethyl)-2-methy...)Show SMILES Cc1c(CCOc2ccc(cc2Cl)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H25Cl2NO3/c1-20-25(16-17-37-29-15-12-23(31(35)36)18-27(29)33)26-19-24(32)13-14-28(26)34(20)30(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-15,18-19,30H,16-17H2,1H3,(H,35,36) | PDB
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| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180083
(4-[2-[[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-...)Show SMILES Cc1c(CCS(=O)CCc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H30ClNO3S/c1-23-29(19-21-39(38)20-18-24-12-14-27(15-13-24)33(36)37)30-22-28(34)16-17-31(30)35(23)32(25-8-4-2-5-9-25)26-10-6-3-7-11-26/h2-17,22,32H,18-21H2,1H3,(H,36,37) | PDB
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PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180098
(CHEMBL199867 | methyl 4-[2-[2-tertbutyl-5-chloro-1...)Show SMILES COC(=O)c1ccc(OCCc2c(n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)C(C)(C)C)cc1 Show InChI InChI=1S/C35H34ClNO3/c1-35(2,3)33-29(21-22-40-28-18-15-26(16-19-28)34(38)39-4)30-23-27(36)17-20-31(30)37(33)32(24-11-7-5-8-12-24)25-13-9-6-10-14-25/h5-20,23,32H,21-22H2,1-4H3 | PDB
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| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180069
(4-[4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-i...)Show SMILES Cc1c(CCOc2ccc(CCCC(O)=O)cc2)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C34H32ClNO3/c1-24-30(21-22-39-29-18-15-25(16-19-29)9-8-14-33(37)38)31-23-28(35)17-20-32(31)36(24)34(26-10-4-2-5-11-26)27-12-6-3-7-13-27/h2-7,10-13,15-20,23,34H,8-9,14,21-22H2,1H3,(H,37,38) | PDB
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PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180064
(4-[2-[1-(diphenylmethyl)-2-methyl-5-morpholin-4-yl...)Show SMILES Cc1c(CCOc2ccc(cc2)C(O)=O)c2cc(ccc2n1C(c1ccccc1)c1ccccc1)N1CCOCC1 Show InChI InChI=1S/C35H34N2O4/c1-25-31(18-21-41-30-15-12-28(13-16-30)35(38)39)32-24-29(36-19-22-40-23-20-36)14-17-33(32)37(25)34(26-8-4-2-5-9-26)27-10-6-3-7-11-27/h2-17,24,34H,18-23H2,1H3,(H,38,39) | PDB
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180093
(4-[[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-ind...)Show SMILES Cc1c(CCNc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H27ClN2O2/c1-21-27(18-19-33-26-15-12-24(13-16-26)31(35)36)28-20-25(32)14-17-29(28)34(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30,33H,18-19H2,1H3,(H,35,36) | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180074
(4-[[[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol...)Show SMILES Cc1c(C(=O)C(=O)Nc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H23ClN2O4/c1-19-27(29(35)30(36)33-24-15-12-22(13-16-24)31(37)38)25-18-23(32)14-17-26(25)34(19)28(20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-18,28H,1H3,(H,33,36)(H,37,38) | PDB
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PC sid
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| Article
PubMed
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180082
(4-[[[3-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-in...)Show SMILES Cc1c(CCC(=O)NCc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H29ClN2O3/c1-22-28(17-19-31(37)35-21-23-12-14-26(15-13-23)33(38)39)29-20-27(34)16-18-30(29)36(22)32(24-8-4-2-5-9-24)25-10-6-3-7-11-25/h2-16,18,20,32H,17,19,21H2,1H3,(H,35,37)(H,38,39) | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180073
(4-[2-[1-(diphenylmethyl)-2-methyl-5-phenyl-1H-indo...)Show SMILES Cc1c(CCOc2ccc(cc2)C(O)=O)c2cc(ccc2n1C(c1ccccc1)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C37H31NO3/c1-26-33(23-24-41-32-20-17-30(18-21-32)37(39)40)34-25-31(27-11-5-2-6-12-27)19-22-35(34)38(26)36(28-13-7-3-8-14-28)29-15-9-4-10-16-29/h2-22,25,36H,23-24H2,1H3,(H,39,40) | PDB
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180067
(4-[[[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-in...)Show SMILES Cc1c(CCOC(=O)Nc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H27ClN2O4/c1-21-27(18-19-39-32(38)34-26-15-12-24(13-16-26)31(36)37)28-20-25(33)14-17-29(28)35(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,38)(H,36,37) | PDB
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UniChem
| Article
PubMed
| n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180080
(3-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indo...)Show SMILES Cc1c(CCOc2cc(on2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H23ClN2O4/c1-18-22(14-15-34-26-17-25(28(32)33)35-30-26)23-16-21(29)12-13-24(23)31(18)27(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-13,16-17,27H,14-15H2,1H3,(H,32,33) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180075
(4-(3-(1-benzhydryl-6-chloro-1H-indol-3-yl)-2-hydro...)Show SMILES OC(COc1ccc(cc1)C(O)=O)Cc1cn(C(c2ccccc2)c2ccccc2)c2cc(Cl)ccc12 Show InChI InChI=1S/C31H26ClNO4/c32-25-13-16-28-24(17-26(34)20-37-27-14-11-23(12-15-27)31(35)36)19-33(29(28)18-25)30(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-16,18-19,26,30,34H,17,20H2,(H,35,36) | PDB
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UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180092
(4-[2-[5-chloro-1-(diphenylmethyl)-2-phenyl-1H-indo...)Show SMILES OC(=O)c1ccc(OCCc2c(-c3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C36H28ClNO3/c37-29-18-21-33-32(24-29)31(22-23-41-30-19-16-28(17-20-30)36(39)40)35(27-14-8-3-9-15-27)38(33)34(25-10-4-1-5-11-25)26-12-6-2-7-13-26/h1-21,24,34H,22-23H2,(H,39,40) | PDB
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UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180089
(6-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indo...)Show SMILES Cc1c(CCOc2ccc(cn2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H25ClN2O3/c1-20-25(16-17-36-28-15-12-23(19-32-28)30(34)35)26-18-24(31)13-14-27(26)33(20)29(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-15,18-19,29H,16-17H2,1H3,(H,34,35) | PDB
MMDB
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UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180094
(3-(3-(1-benzhydryl-6-chloro-1H-indol-3-yl)-2-hydro...)Show SMILES OC(Cc1cn(C(c2ccccc2)c2ccccc2)c2cc(Cl)ccc12)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C31H26ClNO3/c32-26-14-15-28-25(18-27(34)17-21-8-7-13-24(16-21)31(35)36)20-33(29(28)19-26)30(22-9-3-1-4-10-22)23-11-5-2-6-12-23/h1-16,19-20,27,30,34H,17-18H2,(H,35,36) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180095
(4-[2-[[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-...)Show SMILES Cc1c(CCS(=O)(=O)CCc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H30ClNO4S/c1-23-29(19-21-40(38,39)20-18-24-12-14-27(15-13-24)33(36)37)30-22-28(34)16-17-31(30)35(23)32(25-8-4-2-5-9-25)26-10-6-3-7-11-26/h2-17,22,32H,18-21H2,1H3,(H,36,37) | PDB
MMDB
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UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180060
(3-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indo...)Show SMILES Cc1c(CCOc2cccc(c2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO3/c1-21-27(17-18-36-26-14-8-13-24(19-26)31(34)35)28-20-25(32)15-16-29(28)33(21)30(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-16,19-20,30H,17-18H2,1H3,(H,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180090
(3-((1-benzhydryl-6-chloro-1H-indol-3-yl)methyl)-2-...)Show SMILES COc1c(Cc2cn(C(c3ccccc3)c3ccccc3)c3cc(Cl)ccc23)cccc1C(O)=O Show InChI InChI=1S/C30H24ClNO3/c1-35-29-22(13-8-14-26(29)30(33)34)17-23-19-32(27-18-24(31)15-16-25(23)27)28(20-9-4-2-5-10-20)21-11-6-3-7-12-21/h2-16,18-19,28H,17H2,1H3,(H,33,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50136730
(4-((1-benzhydryl-6-chloro-1H-indol-3-yl)methyl)-3-...)Show SMILES COc1cc(ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2cc(Cl)ccc12)C(O)=O Show InChI InChI=1S/C30H24ClNO3/c1-35-28-17-23(30(33)34)13-12-22(28)16-24-19-32(27-18-25(31)14-15-26(24)27)29(20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15,17-19,29H,16H2,1H3,(H,33,34) | PDB
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UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180078
(CHEMBL371299 | [5-chloro-1-(diphenylmethyl)-2-meth...)Show SMILES Cc1c(CC(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H20ClNO2/c1-16-20(15-23(27)28)21-14-19(25)12-13-22(21)26(16)24(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-14,24H,15H2,1H3,(H,27,28) | PDB
MMDB
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UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.65E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180061
(4-(2-hydroxy-3-(4-(5-phenylpentylthio)phenoxy)prop...)Show SMILES OC(COc1ccc(SCCCCCc2ccccc2)cc1)COc1ccc(cc1)C(O)=O Show InChI InChI=1S/C27H30O5S/c28-23(19-31-24-12-10-22(11-13-24)27(29)30)20-32-25-14-16-26(17-15-25)33-18-6-2-5-9-21-7-3-1-4-8-21/h1,3-4,7-8,10-17,23,28H,2,5-6,9,18-20H2,(H,29,30) | PDB
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UniProtKB/SwissProt
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antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay |
J Med Chem 49: 135-58 (2006)
Article DOI: 10.1021/jm0507882
BindingDB Entry DOI: 10.7270/Q2MC8ZMP |
More data for this
Ligand-Target Pair | |
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