Affinity Data by PubMed id=16441060

PubMed code 16441060

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM15236 (3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of MLCK				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM59087 (CHEMBL258765 \| Fasca-plysi \| Fascaplysin) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of CDK4				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM19459 (5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...) Show SMILES Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of EGFR				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50241222 (CHEMBL242740 \| Tectorigenin \| psi-tectorigenin) Show SMILES COc1c(O)cc2occ(-c3ccc(O)cc3)c(=O)c2c1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of EGFR				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 6 (Homo sapiens (Human))	BDBM59087 (CHEMBL258765 \| Fasca-plysi \| Fascaplysin) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of CDK6				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50042949 ((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...) Show SMILES Oc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of EGFR				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM50045936 ((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol \| (E)-...) Show SMILES Oc1cc(O)cc(\C=C\c2ccc(O)c(O)c2)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of MLCK				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM7460 (2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of LCK				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50042949 ((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...) Show SMILES Oc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of c-Src				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50045936 ((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol \| (E)-...) Show SMILES Oc1cc(O)cc(\C=C\c2ccc(O)c(O)c2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of LCK				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50250286 (CHEMBL490510 \| Marein) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+7	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of EGFR				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM23446 (3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop...) Show SMILES Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+7	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of EGFR				J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%