Affinity Data by PubMed id=16458511

PubMed code 16458511

Found 44 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24127 ((4R)-4-(3-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24128 (4-(3-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3,4-te...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	306	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24136 (4-(3-hydroxyphenyl)-7-iodo-N,N-dimethyl-1,2,3,4-te...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	317	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24143 (8-ethyl-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-t...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	344	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24147 (6-(3-hydroxyphenyl)-N,N-dimethyl-4-azatricyclo[8.4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	477	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24137 (4-(3-hydroxyphenyl)-N,N,7-trimethyl-1,2,3,4-tetrah...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	595	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24138 (4-(3-hydroxyphenyl)-7-methoxy-N,N-dimethyl-1,2,3,4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	617	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24148 (10-(3-hydroxyphenyl)-N,N-dimethyl-3-oxa-12-azatric...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	639	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24135 (7-bromo-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-t...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	808	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24146 (7,8-dichloro-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24144 (4-(3-hydroxyphenyl)-8-methoxy-N,N-dimethyl-1,2,3,4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24110 (2-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...) Show SMILES Cc1ccc2C(CN(CCN)Cc2c1C)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.27E+3	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24134 (7-chloro-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24123 (N,N,7,8-tetramethyl-4-phenyl-1,2,3,4-tetrahydroiso...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24111 (3-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...) Show SMILES Cc1ccc2C(CN(CCCN)Cc2c1C)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.06E+3	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24131 (4-(3-chlorophenyl)-N,N,7,8-tetramethyl-1,2,3,4-tet...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24112 (4-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...) Show SMILES Cc1ccc2C(CN(CCCCN)Cc2c1C)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.65E+3	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24142 (4-(3-hydroxyphenyl)-N,N,8-trimethyl-1,2,3,4-tetrah...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24115 ([4-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoqui...) Show SMILES CN(C)CCCCN1CC(c2ccccc2)c2ccc(C)c(C)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.36E+3	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24126 (N-[3-(dimethylamino)propyl]-N,7,8-trimethyl-4-phen...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.44E+3	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24105 (7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinoli...) Show SMILES Cc1ccc2C(CNCc2c1C)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.33E+3	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24114 ([3-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoqui...) Show SMILES CN(C)CCCN1CC(c2ccccc2)c2ccc(C)c(C)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.88E+3	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24108 (7,8-dimethyl-4-phenyl-2-(propan-2-yl)-1,2,3,4-tetr...) Show SMILES CC(C)N1CC(c2ccccc2)c2ccc(C)c(C)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24125 (7,8-dimethyl-4-phenyl-2-(piperidin-1-ylcarbonyl)-1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24145 (4-(3-hydroxyphenyl)-7,8-dimethoxy-N,N-dimethyl-1,2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24130 (N,N,7,8-tetramethyl-4-[3-(trifluoromethyl)phenyl]-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24119 (methyl 7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroiso...) Show SMILES COC(=O)N1CC(c2ccccc2)c2ccc(C)c(C)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24117 (2-benzoyl-7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24116 (1-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...) Show SMILES CC(=O)N1CC(c2ccccc2)c2ccc(C)c(C)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24106 (2,7,8-trimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...) Show SMILES CN1CC(c2ccccc2)c2ccc(C)c(C)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.84E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24124 (4-[(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoqui...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.23E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24139 (8-fluoro-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24118 (2-methanesulfonyl-7,8-dimethyl-4-phenyl-1,2,3,4-te...) Show SMILES Cc1ccc2C(CN(Cc2c1C)S(C)(=O)=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24122 (N,7,8-trimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...) Show SMILES CNC(=O)N1CC(c2ccccc2)c2ccc(C)c(C)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24109 (7,8-dimethyl-4-phenyl-2-(2-phenylethyl)-1,2,3,4-te...) Show SMILES Cc1ccc2C(CN(CCc3ccccc3)Cc2c1C)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24120 (ethyl 7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoq...) Show SMILES CCOC(=O)N1CC(c2ccccc2)c2ccc(C)c(C)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24132 (4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-tetrahydr...) Show SMILES CN(C)C(=O)N1CC(c2cccc(O)c2)c2ccccc2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24141 (8-bromo-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-t...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24121 (7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinoli...) Show SMILES Cc1ccc2C(CN(Cc2c1C)C(N)=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24113 (7,8-dimethyl-4-phenyl-2-[2-(1H-pyrrol-1-yl)ethyl]-...) Show SMILES Cc1ccc2C(CN(CCn3cccc3)Cc2c1C)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24129 (4-(4-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3,4-te...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (docked)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24140 (8-chloro-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24133 (7-fluoro-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM24107 (2-ethyl-7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydrois...) Show SMILES CCN1CC(c2ccccc2)c2ccc(C)c(C)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.52E+4	n/a	n/a	n/a	n/a	7.0	23
Bristol-Myers Squibb Company					Assay Description ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).				Bioorg Med Chem Lett 16: 2095-100 (2006) Article DOI: 10.1016/j.bmcl.2006.01.056 BindingDB Entry DOI: 10.7270/Q2VM49KF
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair

* indicates data uncertainty>20%