Affinity Data by PubMed id=19608417

PubMed code 19608417

Found 26 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296974 (4-((1H-imidazol-1-yl)methyl)phenyl 4-iodobenzenesu...) Show SMILES Ic1ccc(cc1)S(=O)(=O)Oc1ccc(Cn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65.1	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50188097 (1-(4-Chlorobenzyl)-1H-imidazole \| CHEMBL441367) Show SMILES Clc1ccc(Cn2ccnc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of aromatase				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296973 (4-((1H-imidazol-1-yl)methyl)phenyl 4-bromobenzenes...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70.4	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296970 (4-((1H-imidazol-1-yl)methyl)phenyl 4-nitrobenzenes...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296972 (4-((1H-imidazol-1-yl)methyl)phenyl 4-chlorobenzene...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98.7	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296975 (4-((1H-imidazol-1-yl)methyl)phenyl 4-methoxybenzen...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50188093 (1-(4-Nitro-benzyl)-1H-imidazole \| 1-(4-nitrobenzyl...) Show SMILES [O-][N+](=O)c1ccc(Cn2ccnc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of aromatase				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296971 (4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...) Show SMILES Fc1ccc(cc1)S(=O)(=O)Oc1ccc(Cn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296969 (4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Oc1ccc(Cn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296976 (4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	291	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50188085 (1-(4-Fluorobenzyl)-1H-imidazole \| CHEMBL377770) Show SMILES Fc1ccc(Cn2ccnc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of aromatase				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50008733 (1-(4-Cyanobenzyl)-1H-imidazole \| 4-((1H-imidazol-1...) Show SMILES N#Cc1ccc(Cn2ccnc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of aromatase				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50188092 (1-(4-iodobenzyl)-1H-imidazole \| 4-iodobenzyl imida...) Show SMILES Ic1ccc(Cn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM31768 (CHEMBL295698 \| Ketoconazole \| Nizoral \| Panfungol) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM31768 (CHEMBL295698 \| Ketoconazole \| Nizoral \| Panfungol) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296973 (4-((1H-imidazol-1-yl)methyl)phenyl 4-bromobenzenes...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296975 (4-((1H-imidazol-1-yl)methyl)phenyl 4-methoxybenzen...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296972 (4-((1H-imidazol-1-yl)methyl)phenyl 4-chlorobenzene...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296970 (4-((1H-imidazol-1-yl)methyl)phenyl 4-nitrobenzenes...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296974 (4-((1H-imidazol-1-yl)methyl)phenyl 4-iodobenzenesu...) Show SMILES Ic1ccc(cc1)S(=O)(=O)Oc1ccc(Cn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50188092 (1-(4-iodobenzyl)-1H-imidazole \| 4-iodobenzyl imida...) Show SMILES Ic1ccc(Cn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296971 (4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...) Show SMILES Fc1ccc(cc1)S(=O)(=O)Oc1ccc(Cn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50188087 (1-(4-methyl-benzyl)-1H-imidazole \| 1-(4-methylbenz...) Show SMILES Cc1ccc(Cn2ccnc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of aromatase				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296969 (4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Oc1ccc(Cn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50296976 (4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM4339 ((3,4-Dihydroxybenzylidene)malononitrile \| 2-[(3,4-...) Show SMILES [#8]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1-[#8] Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the West of Scotland Curated by ChEMBL					Assay Description Inhibition of aromatase				Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72
University of the West of Scotland Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%