Found 48 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310682
((S)-2-amino-N-((S)-1-cyano-2-(5-phenylthiophen-2-y...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@H](Cc1ccc(s1)-c1ccccc1)C#N |r| Show InChI InChI=1S/C20H19N3OS2/c21-13-15(23-20(24)18(22)12-16-7-4-10-25-16)11-17-8-9-19(26-17)14-5-2-1-3-6-14/h1-10,15,18H,11-12,22H2,(H,23,24)/t15-,18-/m0/s1 | PDB
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UniProtKB/SwissProt
B.MOAD
antibodypedia
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AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310681
((S)-2-amino-N-((S)-2-(benzo[d]thiazol-2-yl)-1-cyan...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@H](Cc1nc2ccccc2s1)C#N |r| Show InChI InChI=1S/C17H16N4OS2/c18-10-11(8-16-21-14-5-1-2-6-15(14)24-16)20-17(22)13(19)9-12-4-3-7-23-12/h1-7,11,13H,8-9,19H2,(H,20,22)/t11-,13-/m0/s1 | PDB
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UniProtKB/SwissProt
B.MOAD
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310678
((S)-2-amino-N-((S)-1-cyano-2-phenylethyl)-3-(thiop...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@H](Cc1ccccc1)C#N |r| Show InChI InChI=1S/C16H17N3OS/c17-11-13(9-12-5-2-1-3-6-12)19-16(20)15(18)10-14-7-4-8-21-14/h1-8,13,15H,9-10,18H2,(H,19,20)/t13-,15-/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310680
((S)-2-amino-N-((S)-1-cyano-2-(naphthalen-2-yl)ethy...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C#N |r| Show InChI InChI=1S/C20H19N3OS/c21-13-17(23-20(24)19(22)12-18-6-3-9-25-18)11-14-7-8-15-4-1-2-5-16(15)10-14/h1-10,17,19H,11-12,22H2,(H,23,24)/t17-,19-/m0/s1 | PDB
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PC cid
PC sid
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| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310700
((2S,4R)-N-((S)-1-cyano-2-phenylethyl)-4-(methylthi...)Show SMILES CS[C@@]1(CN[C@@H](C1)C(=O)N[C@@H](Cc1ccccc1)C#N)c1ccccc1 |r| Show InChI InChI=1S/C21H23N3OS/c1-26-21(17-10-6-3-7-11-17)13-19(23-15-21)20(25)24-18(14-22)12-16-8-4-2-5-9-16/h2-11,18-19,23H,12-13,15H2,1H3,(H,24,25)/t18-,19-,21-/m0/s1 | PDB
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PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310676
((S)-2-amino-N-((S)-1-cyano-2,2-diphenylethyl)-3-(t...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@H](C#N)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C22H21N3OS/c23-15-20(25-22(26)19(24)14-18-12-7-13-27-18)21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-13,19-21H,14,24H2,(H,25,26)/t19-,20+/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310677
((S)-2-amino-N-((S)-1-cyano-2-cyclohexylethyl)-3-(t...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@H](CC1CCCCC1)C#N |r| Show InChI InChI=1S/C16H23N3OS/c17-11-13(9-12-5-2-1-3-6-12)19-16(20)15(18)10-14-7-4-8-21-14/h4,7-8,12-13,15H,1-3,5-6,9-10,18H2,(H,19,20)/t13-,15-/m0/s1 | PDB
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310673
((S)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C#N |r| Show InChI InChI=1S/C18H18N4OS/c19-10-13(8-12-11-21-17-6-2-1-5-15(12)17)22-18(23)16(20)9-14-4-3-7-24-14/h1-7,11,13,16,21H,8-9,20H2,(H,22,23)/t13-,16-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310699
((2S,4R)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-p...)Show SMILES F[C@@]1(CN[C@@H](C1)C(=O)N[C@@H](Cc1ccccc1)C#N)c1ccccc1 |r| Show InChI InChI=1S/C20H20FN3O/c21-20(16-9-5-2-6-10-16)12-18(23-14-20)19(25)24-17(13-22)11-15-7-3-1-4-8-15/h1-10,17-18,23H,11-12,14H2,(H,24,25)/t17-,18-,20-/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310679
((S)-2-amino-N-((S)-1-cyano-3-phenylpropyl)-3-(thio...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@H](CCc1ccccc1)C#N |r| Show InChI InChI=1S/C17H19N3OS/c18-12-14(9-8-13-5-2-1-3-6-13)20-17(21)16(19)11-15-7-4-10-22-15/h1-7,10,14,16H,8-9,11,19H2,(H,20,21)/t14-,16-/m0/s1 | PDB
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310684
((S)-2-amino-N-(1-cyanocyclopropyl)-3-(thiophen-2-y...)Show InChI InChI=1S/C11H13N3OS/c12-7-11(3-4-11)14-10(15)9(13)6-8-2-1-5-16-8/h1-2,5,9H,3-4,6,13H2,(H,14,15)/t9-/m0/s1 | PDB
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PC cid
PC sid
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Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310690
(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r| Show InChI InChI=1S/C17H17N3OS/c18-11-17(10-14(17)12-5-2-1-3-6-12)20-16(21)15(19)9-13-7-4-8-22-13/h1-8,14-15H,9-10,19H2,(H,20,21)/t14-,15+,17+/m1/s1 | PDB
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PC cid
PC sid
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Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310674
((S)-2-amino-N-(cyanomethyl)-3-(thiophen-2-yl)propa...)Show InChI InChI=1S/C9H11N3OS/c10-3-4-12-9(13)8(11)6-7-2-1-5-14-7/h1-2,5,8H,4,6,11H2,(H,12,13)/t8-/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310689
(CHEMBL1080786 | cis-(S)-2-amino-N-((1S,2S)-1-cyano...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@]1(C[C@H]1c1ccccc1)C#N |r| Show InChI InChI=1S/C17H17N3OS/c18-11-17(10-14(17)12-5-2-1-3-6-12)20-16(21)15(19)9-13-7-4-8-22-13/h1-8,14-15H,9-10,19H2,(H,20,21)/t14-,15-,17+/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310696
((2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-(methylthi...)Show SMILES CS[C@@H]1CN[C@@H](C1)C(=O)N[C@@H](Cc1ccccc1)C#N |r| Show InChI InChI=1S/C15H19N3OS/c1-20-13-8-14(17-10-13)15(19)18-12(9-16)7-11-5-3-2-4-6-11/h2-6,12-14,17H,7-8,10H2,1H3,(H,18,19)/t12-,13-,14-/m0/s1 | PDB
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PC cid
PC sid
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Similars
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310687
((2S)-2-amino-N-(1-cyano-2,2-dimethylcyclopropyl)-3...)Show InChI InChI=1S/C13H17N3OS/c1-12(2)7-13(12,8-14)16-11(17)10(15)6-9-4-3-5-18-9/h3-5,10H,6-7,15H2,1-2H3,(H,16,17)/t10-,13?/m0/s1 | PDB
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PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310694
((2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoropyrr...)Show SMILES F[C@@H]1CN[C@@H](C1)C(=O)N[C@@H](Cc1ccccc1)C#N |r| Show InChI InChI=1S/C14H16FN3O/c15-11-7-13(17-9-11)14(19)18-12(8-16)6-10-4-2-1-3-5-10/h1-5,11-13,17H,6-7,9H2,(H,18,19)/t11-,12-,13-/m0/s1 | PDB
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 133 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310705
(CHEMBL1077666 | Cis-(2S,4S)-N-(2-benzyl-1-cyanocyc...)Show SMILES CS[C@@H]1CN[C@@H](C1)C(=O)NC1(CC1Cc1ccccc1)C#N |r| Show InChI InChI=1S/C17H21N3OS/c1-22-14-8-15(19-10-14)16(21)20-17(11-18)9-13(17)7-12-5-3-2-4-6-12/h2-6,13-15,19H,7-10H2,1H3,(H,20,21)/t13?,14-,15-,17?/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 192 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310705
(CHEMBL1077666 | Cis-(2S,4S)-N-(2-benzyl-1-cyanocyc...)Show SMILES CS[C@@H]1CN[C@@H](C1)C(=O)NC1(CC1Cc1ccccc1)C#N |r| Show InChI InChI=1S/C17H21N3OS/c1-22-14-8-15(19-10-14)16(21)20-17(11-18)9-13(17)7-12-5-3-2-4-6-12/h2-6,13-15,19H,7-10H2,1H3,(H,20,21)/t13?,14-,15-,17?/m0/s1 | PDB
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UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 192 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310669
((S)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)...)Show SMILES CSCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C#N |r| Show InChI InChI=1S/C16H20N4OS/c1-22-7-6-14(18)16(21)20-12(9-17)8-11-10-19-15-5-3-2-4-13(11)15/h2-5,10,12,14,19H,6-8,18H2,1H3,(H,20,21)/t12-,14-/m0/s1 | PDB
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| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310675
((S)-2-amino-N-((S)-1-cyano-2-methylpropyl)-3-(thio...)Show InChI InChI=1S/C12H17N3OS/c1-8(2)11(7-13)15-12(16)10(14)6-9-4-3-5-17-9/h3-5,8,10-11H,6,14H2,1-2H3,(H,15,16)/t10-,11+/m0/s1 | PDB
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| n/a | n/a | 215 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310698
((2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-(ethylthio...)Show SMILES CCS[C@@H]1CN[C@@H](C1)C(=O)N[C@@H](Cc1ccccc1)C#N |r| Show InChI InChI=1S/C16H21N3OS/c1-2-21-14-9-15(18-11-14)16(20)19-13(10-17)8-12-6-4-3-5-7-12/h3-7,13-15,18H,2,8-9,11H2,1H3,(H,19,20)/t13-,14-,15-/m0/s1 | PDB
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| n/a | n/a | 271 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310672
((S)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)...)Show SMILES CC(C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C#N |r| Show InChI InChI=1S/C16H20N4O/c1-10(2)15(18)16(21)20-12(8-17)7-11-9-19-14-6-4-3-5-13(11)14/h3-6,9-10,12,15,19H,7,18H2,1-2H3,(H,20,21)/t12-,15-/m0/s1 | PDB
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| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310702
((2S,4S)-N-(1-cyanocyclopropyl)-4-(methylthio)pyrro...)Show InChI InChI=1S/C10H15N3OS/c1-15-7-4-8(12-5-7)9(14)13-10(6-11)2-3-10/h7-8,12H,2-5H2,1H3,(H,13,14)/t7-,8-/m0/s1 | PDB
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| n/a | n/a | 336 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310693
((2S,4S)-4-chloro-N-((S)-1-cyano-2-phenylethyl)pyrr...)Show SMILES Cl[C@@H]1CN[C@@H](C1)C(=O)N[C@@H](Cc1ccccc1)C#N |r| Show InChI InChI=1S/C14H16ClN3O/c15-11-7-13(17-9-11)14(19)18-12(8-16)6-10-4-2-1-3-5-10/h1-5,11-13,17H,6-7,9H2,(H,18,19)/t11-,12-,13-/m0/s1 | PDB
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| n/a | n/a | 495 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310704
(CHEMBL1078356 | Cis-(2S,4S)-N-(2-benzyl-1-cyanocyc...)Show SMILES F[C@@H]1CN[C@@H](C1)C(=O)NC1(CC1Cc1ccccc1)C#N |r| Show InChI InChI=1S/C16H18FN3O/c17-13-7-14(19-9-13)15(21)20-16(10-18)8-12(16)6-11-4-2-1-3-5-11/h1-5,12-14,19H,6-9H2,(H,20,21)/t12?,13-,14-,16?/m0/s1 | PDB
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| n/a | n/a | 523 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310704
(CHEMBL1078356 | Cis-(2S,4S)-N-(2-benzyl-1-cyanocyc...)Show SMILES F[C@@H]1CN[C@@H](C1)C(=O)NC1(CC1Cc1ccccc1)C#N |r| Show InChI InChI=1S/C16H18FN3O/c17-13-7-14(19-9-13)15(21)20-16(10-18)8-12(16)6-11-4-2-1-3-5-11/h1-5,12-14,19H,6-9H2,(H,20,21)/t12?,13-,14-,16?/m0/s1 | PDB
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| n/a | n/a | 523 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310670
((R)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)...)Show SMILES CCSC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C#N |r| Show InChI InChI=1S/C16H20N4OS/c1-2-22-10-14(18)16(21)20-12(8-17)7-11-9-19-15-6-4-3-5-13(11)15/h3-6,9,12,14,19H,2,7,10,18H2,1H3,(H,20,21)/t12-,14-/m0/s1 | PDB
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| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310701
((2S,4S)-N-(1-cyanocyclopropyl)-4-fluoropyrrolidine...)Show InChI InChI=1S/C9H12FN3O/c10-6-3-7(12-4-6)8(14)13-9(5-11)1-2-9/h6-7,12H,1-4H2,(H,13,14)/t6-,7-/m0/s1 | PDB
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| n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310692
((2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-methoxypyr...)Show SMILES CO[C@@H]1CN[C@@H](C1)C(=O)N[C@@H](Cc1ccccc1)C#N |r| Show InChI InChI=1S/C15H19N3O2/c1-20-13-8-14(17-10-13)15(19)18-12(9-16)7-11-5-3-2-4-6-11/h2-6,12-14,17H,7-8,10H2,1H3,(H,18,19)/t12-,13-,14-/m0/s1 | PDB
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| n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310688
(CHEMBL1081148 | trans-(+/-)-(2S)-2-amino-N-(1-cyan...)Show SMILES N[C@@H](Cc1cccs1)C(=O)NC1(CC1c1ccccc1)C#N |r| Show InChI InChI=1S/C17H17N3OS/c18-11-17(10-14(17)12-5-2-1-3-6-12)20-16(21)15(19)9-13-7-4-8-22-13/h1-8,14-15H,9-10,19H2,(H,20,21)/t14?,15-,17?/m0/s1 | PDB
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| n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310685
((S)-2-amino-N-(2-cyanopropan-2-yl)-3-(thiophen-2-y...)Show InChI InChI=1S/C11H15N3OS/c1-11(2,7-12)14-10(15)9(13)6-8-4-3-5-16-8/h3-5,9H,6,13H2,1-2H3,(H,14,15)/t9-/m0/s1 | PDB
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| n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310671
((S)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)...)Show SMILES CCSCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C#N |r| Show InChI InChI=1S/C17H22N4OS/c1-2-23-8-7-15(19)17(22)21-13(10-18)9-12-11-20-16-6-4-3-5-14(12)16/h3-6,11,13,15,20H,2,7-9,19H2,1H3,(H,21,22)/t13-,15-/m0/s1 | PDB
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| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310686
((S)-2-amino-N-(1-cyanocyclobutyl)-3-(thiophen-2-yl...)Show InChI InChI=1S/C12H15N3OS/c13-8-12(4-2-5-12)15-11(16)10(14)7-9-3-1-6-17-9/h1,3,6,10H,2,4-5,7,14H2,(H,15,16)/t10-/m0/s1 | PDB
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| n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310703
((2S,4S)-N-((1S,2S)-1-cyano-2-phenylcyclopropyl)-4-...)Show SMILES F[C@@H]1CN[C@@H](C1)C(=O)N[C@]1(C[C@H]1c1ccccc1)C#N |r| Show InChI InChI=1S/C15H16FN3O/c16-11-6-13(18-8-11)14(20)19-15(9-17)7-12(15)10-4-2-1-3-5-10/h1-5,11-13,18H,6-8H2,(H,19,20)/t11-,12-,13-,15+/m0/s1 | PDB
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| n/a | n/a | 2.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310691
((2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-methylpyrr...)Show SMILES C[C@@H]1CN[C@@H](C1)C(=O)N[C@@H](Cc1ccccc1)C#N |r| Show InChI InChI=1S/C15H19N3O/c1-11-7-14(17-10-11)15(19)18-13(9-16)8-12-5-3-2-4-6-12/h2-6,11,13-14,17H,7-8,10H2,1H3,(H,18,19)/t11-,13-,14-/m0/s1 | PDB
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| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310697
((S)-N-((S)-1-cyano-2-(4-(methylthio)phenyl)ethyl)p...)Show SMILES CSc1ccc(C[C@H](NC(=O)[C@@H]2CCCN2)C#N)cc1 |r| Show InChI InChI=1S/C15H19N3OS/c1-20-13-6-4-11(5-7-13)9-12(10-16)18-15(19)14-3-2-8-17-14/h4-7,12,14,17H,2-3,8-9H2,1H3,(H,18,19)/t12-,14-/m0/s1 | PDB
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| n/a | n/a | 2.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310683
((S)-2-amino-N-((S)-1-cyano-2,2-dimethylpropyl)-3-(...)Show SMILES CC(C)(C)[C@H](NC(=O)[C@@H](N)Cc1cccs1)C#N |r| Show InChI InChI=1S/C13H19N3OS/c1-13(2,3)11(8-14)16-12(17)10(15)7-9-5-4-6-18-9/h4-6,10-11H,7,15H2,1-3H3,(H,16,17)/t10-,11+/m0/s1 | PDB
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| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50186092
((S)-N-((S)-1-cyano-2-phenylethyl)pyrrolidine-2-car...)Show InChI InChI=1S/C14H17N3O/c15-10-12(9-11-5-2-1-3-6-11)17-14(18)13-7-4-8-16-13/h1-3,5-6,12-13,16H,4,7-9H2,(H,17,18)/t12-,13-/m0/s1 | PDB
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| n/a | n/a | 4.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50310690
(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r| Show InChI InChI=1S/C17H17N3OS/c18-11-17(10-14(17)12-5-2-1-3-6-12)20-16(21)15(19)9-13-7-4-8-22-13/h1-8,14-15H,9-10,19H2,(H,20,21)/t14-,15+,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human cathepsin L |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50310690
(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r| Show InChI InChI=1S/C17H17N3OS/c18-11-17(10-14(17)12-5-2-1-3-6-12)20-16(21)15(19)9-13-7-4-8-22-13/h1-8,14-15H,9-10,19H2,(H,20,21)/t14-,15+,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human cathepsin S |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310695
((S)-N-((S)-1-cyano-2-(4-fluorophenyl)ethyl)pyrroli...)Show SMILES Fc1ccc(C[C@H](NC(=O)[C@@H]2CCCN2)C#N)cc1 |r| Show InChI InChI=1S/C14H16FN3O/c15-11-5-3-10(4-6-11)8-12(9-16)18-14(19)13-2-1-7-17-13/h3-6,12-13,17H,1-2,7-8H2,(H,18,19)/t12-,13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50310668
((S)-N-(2-(1H-indol-3-yl)ethyl)-2-amino-4-(methylth...)Show InChI InChI=1S/C15H21N3OS/c1-20-9-7-13(16)15(19)17-8-6-11-10-18-14-5-3-2-4-12(11)14/h2-5,10,13,18H,6-9,16H2,1H3,(H,17,19)/t13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin C |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Pro-cathepsin H
(Homo sapiens (Human)) | BDBM50310690
(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r| Show InChI InChI=1S/C17H17N3OS/c18-11-17(10-14(17)12-5-2-1-3-6-12)20-16(21)15(19)9-13-7-4-8-22-13/h1-8,14-15H,9-10,19H2,(H,20,21)/t14-,15+,17+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human cathepsin H |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50310690
(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r| Show InChI InChI=1S/C17H17N3OS/c18-11-17(10-14(17)12-5-2-1-3-6-12)20-16(21)15(19)9-13-7-4-8-22-13/h1-8,14-15H,9-10,19H2,(H,20,21)/t14-,15+,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human Neutrophil elastase |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Cathepsin G
(Homo sapiens (Human)) | BDBM50310690
(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r| Show InChI InChI=1S/C17H17N3OS/c18-11-17(10-14(17)12-5-2-1-3-6-12)20-16(21)15(19)9-13-7-4-8-22-13/h1-8,14-15H,9-10,19H2,(H,20,21)/t14-,15+,17+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human cathepsin G |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Myeloblastin
(Homo sapiens (Human)) | BDBM50310690
(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r| Show InChI InChI=1S/C17H17N3OS/c18-11-17(10-14(17)12-5-2-1-3-6-12)20-16(21)15(19)9-13-7-4-8-22-13/h1-8,14-15H,9-10,19H2,(H,20,21)/t14-,15+,17+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human Proteinase-3 |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
Cathepsin B
(Homo sapiens (Human)) | BDBM50310690
(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r| Show InChI InChI=1S/C17H17N3OS/c18-11-17(10-14(17)12-5-2-1-3-6-12)20-16(21)15(19)9-13-7-4-8-22-13/h1-8,14-15H,9-10,19H2,(H,20,21)/t14-,15+,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co.
Curated by ChEMBL
| Assay Description
Inhibition of human cathepsin B |
Bioorg Med Chem Lett 19: 5392-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.114
BindingDB Entry DOI: 10.7270/Q298874W |
More data for this
Ligand-Target Pair | |
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