Found 26 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301643
(CHEMBL570633 | trans-3'-oxo-N-(5-phenylpyrimidin-2...)Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccccc21 |r,wU:18.23,wD:15.16,(-7.28,6.74,;-5.95,5.97,;-4.61,6.74,;-3.28,5.97,;-3.29,4.43,;-1.96,3.66,;-.62,4.43,;-.62,5.98,;-1.96,6.74,;.71,3.66,;.71,2.12,;2.05,1.35,;3.38,2.13,;3.37,3.67,;2.04,4.43,;-5.95,4.43,;-7.28,3.65,;-7.28,2.11,;-5.95,1.35,;-4.62,2.11,;-4.62,3.65,;-5.03,.1,;-5.93,-1.16,;-5.45,-2.62,;-7.41,-.69,;-8.75,-1.46,;-10.08,-.69,;-10.08,.86,;-8.75,1.63,;-7.42,.86,)| Show InChI InChI=1S/C24H21N3O3/c28-21(27-23-25-14-18(15-26-23)16-6-2-1-3-7-16)17-10-12-24(13-11-17)20-9-5-4-8-19(20)22(29)30-24/h1-9,14-15,17H,10-13H2,(H,25,26,27,28)/t17-,24- | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301652
(CHEMBL584526 | trans-N-(5-(3-fluorophenyl)pyrimidi...)Show SMILES Fc1cccc(c1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:17.21,wD:14.14,(4.28,-10.52,;2.95,-11.3,;2.96,-12.85,;1.63,-13.62,;.29,-12.85,;.29,-11.31,;1.62,-10.54,;-1.04,-10.54,;-2.38,-11.31,;-3.71,-10.54,;-3.7,-9,;-5.03,-8.23,;-6.37,-9,;-7.7,-8.23,;-6.37,-10.54,;-7.7,-11.32,;-7.7,-12.86,;-6.37,-13.62,;-5.04,-12.86,;-5.04,-11.32,;-5.45,-14.87,;-6.35,-16.13,;-5.87,-17.59,;-7.83,-15.66,;-9.17,-16.43,;-10.5,-15.66,;-10.5,-14.12,;-9.17,-13.35,;-7.84,-14.11,;-2.38,-8.23,;-1.04,-8.99,)| Show InChI InChI=1S/C23H19FN4O3/c24-17-3-1-2-15(10-17)16-11-26-22(27-12-16)28-20(29)14-4-7-23(8-5-14)19-6-9-25-13-18(19)21(30)31-23/h1-3,6,9-14H,4-5,7-8H2,(H,26,27,28,29)/t14-,23- | KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301642
(CHEMBL567495 | trans-N-(5-(2-fluorophenyl)pyrimidi...)Show SMILES Fc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:17.21,wD:14.14,(31.68,5.18,;31.69,3.64,;33.02,2.88,;33.03,1.33,;31.69,.56,;30.36,1.33,;30.36,2.87,;29.03,3.64,;27.69,2.87,;26.36,3.64,;26.37,5.18,;25.04,5.95,;23.7,5.18,;22.37,5.95,;23.7,3.64,;22.37,2.86,;22.37,1.32,;23.7,.56,;25.03,1.32,;25.03,2.86,;24.62,-.69,;23.72,-1.95,;24.2,-3.41,;22.24,-1.48,;20.9,-2.25,;19.56,-1.48,;19.57,.06,;20.9,.83,;22.23,.07,;27.69,5.95,;29.02,5.19,)| Show InChI InChI=1S/C23H19FN4O3/c24-19-4-2-1-3-16(19)15-11-26-22(27-12-15)28-20(29)14-5-8-23(9-6-14)18-7-10-25-13-17(18)21(30)31-23/h1-4,7,10-14H,5-6,8-9H2,(H,26,27,28,29)/t14-,23- | KEGG
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| CHEMBL
PC cid
PC sid
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| Article
PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301655
(CHEMBL567310 | trans-N-(5-(3-(fluoromethoxy)phenyl...)Show SMILES FCOc1cccc(c1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:19.23,wD:16.16,(33.32,-25.03,;31.99,-25.81,;30.65,-25.04,;29.32,-25.82,;29.33,-27.37,;27.99,-28.14,;26.66,-27.37,;26.66,-25.83,;27.99,-25.06,;25.33,-25.06,;23.99,-25.83,;22.66,-25.06,;22.67,-23.52,;21.33,-22.75,;20,-23.52,;18.67,-22.75,;20,-25.06,;18.67,-25.84,;18.67,-27.38,;20,-28.14,;21.33,-27.38,;21.33,-25.84,;20.92,-29.39,;20.02,-30.65,;20.5,-32.11,;18.54,-30.18,;17.2,-30.95,;15.86,-30.18,;15.86,-28.64,;17.19,-27.87,;18.53,-28.63,;23.99,-22.75,;25.32,-23.51,)| Show InChI InChI=1S/C24H21FN4O4/c25-14-32-18-3-1-2-16(10-18)17-11-27-23(28-12-17)29-21(30)15-4-7-24(8-5-15)20-6-9-26-13-19(20)22(31)33-24/h1-3,6,9-13,15H,4-5,7-8,14H2,(H,27,28,29,30)/t15-,24- | KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301640
(CHEMBL585107 | trans-N-(5-(3-(fluoromethyl)phenyl)...)Show SMILES FCc1cccc(c1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)nc1 |r,wU:18.22,wD:15.15,(30.84,-33.5,;29.51,-32.74,;28.18,-33.51,;28.18,-35.06,;26.85,-35.83,;25.52,-35.06,;25.52,-33.52,;26.84,-32.75,;24.18,-32.75,;22.85,-33.52,;21.52,-32.75,;21.52,-31.22,;20.19,-30.45,;18.86,-31.22,;17.52,-30.45,;18.86,-32.76,;17.53,-33.53,;17.53,-35.07,;18.86,-35.84,;20.19,-35.07,;20.19,-33.53,;19.78,-37.08,;18.87,-38.35,;19.36,-39.81,;17.39,-37.87,;16.05,-38.65,;14.72,-37.87,;14.72,-36.33,;16.05,-35.56,;17.38,-36.32,;22.85,-30.44,;24.18,-31.21,)| Show InChI InChI=1S/C24H21FN4O3/c25-11-15-2-1-3-17(10-15)18-12-27-23(28-13-18)29-21(30)16-4-7-24(8-5-16)20-14-26-9-6-19(20)22(31)32-24/h1-3,6,9-10,12-14,16H,4-5,7-8,11H2,(H,27,28,29,30)/t16-,24- | KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301656
(CHEMBL567527 | trans-1'-oxo-N-(5-phenylpyrimidin-2...)Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:18.23,wD:15.16,(28.35,-35.04,;29.11,-36.37,;30.65,-36.38,;31.49,-37.67,;30.78,-39.03,;31.62,-40.33,;33.16,-40.25,;33.86,-38.87,;33.02,-37.58,;34,-41.54,;33.29,-42.91,;34.13,-44.2,;35.67,-44.13,;36.37,-42.75,;35.53,-41.46,;28.34,-37.71,;26.8,-37.71,;26.03,-39.04,;26.8,-40.37,;28.34,-40.37,;29.11,-39.04,;27.72,-41.62,;26.81,-42.88,;27.29,-44.34,;25.33,-42.4,;24,-43.17,;22.67,-42.4,;22.67,-40.86,;24,-40.09,;25.33,-40.85,)| Show InChI InChI=1S/C23H20N4O3/c28-20(27-22-25-12-17(13-26-22)15-4-2-1-3-5-15)16-6-9-23(10-7-16)19-14-24-11-8-18(19)21(29)30-23/h1-5,8,11-14,16H,6-7,9-10H2,(H,25,26,27,28)/t16-,23- | KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301657
(CHEMBL585203 | trans-N-(5-(2-fluorophenyl)pyrimidi...)Show SMILES Fc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)nc1 |r,wU:17.21,wD:14.14,(26.17,5.24,;26.17,3.7,;27.51,2.93,;27.51,1.39,;26.18,.61,;24.85,1.38,;24.85,2.92,;23.51,3.69,;22.18,2.92,;20.85,3.69,;20.86,5.23,;19.52,6,;18.19,5.23,;16.85,6,;18.19,3.69,;16.86,2.91,;16.86,1.37,;18.19,.61,;19.52,1.37,;19.52,2.91,;19.11,-.64,;18.2,-1.9,;18.69,-3.36,;16.73,-1.43,;15.38,-2.2,;14.05,-1.43,;14.05,.12,;15.38,.89,;16.72,.12,;22.18,6,;23.51,5.24,)| Show InChI InChI=1S/C23H19FN4O3/c24-19-4-2-1-3-16(19)15-11-26-22(27-12-15)28-20(29)14-5-8-23(9-6-14)18-13-25-10-7-17(18)21(30)31-23/h1-4,7,10-14H,5-6,8-9H2,(H,26,27,28,29)/t14-,23- | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301658
(CHEMBL570864 | trans-N-(5-(3-fluorophenyl)pyrimidi...)Show SMILES Fc1cccc(c1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)nc1 |r,wU:17.21,wD:14.14,(4.64,-10.09,;3.31,-10.86,;3.32,-12.41,;1.98,-13.18,;.65,-12.42,;.65,-10.87,;1.98,-10.1,;-.68,-10.11,;-2.02,-10.88,;-3.35,-10.11,;-3.34,-8.57,;-4.67,-7.8,;-6.01,-8.57,;-7.34,-7.8,;-6.01,-10.11,;-7.34,-10.88,;-7.34,-12.42,;-6.01,-13.19,;-4.68,-12.42,;-4.68,-10.88,;-5.09,-14.44,;-5.99,-15.7,;-5.51,-17.16,;-7.47,-15.23,;-8.81,-16,;-10.15,-15.23,;-10.14,-13.68,;-8.82,-12.91,;-7.48,-13.67,;-2.02,-7.79,;-.69,-8.56,)| Show InChI InChI=1S/C23H19FN4O3/c24-17-3-1-2-15(10-17)16-11-26-22(27-12-16)28-20(29)14-4-7-23(8-5-14)19-13-25-9-6-18(19)21(30)31-23/h1-3,6,9-14H,4-5,7-8H2,(H,26,27,28,29)/t14-,23- | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301661
(CHEMBL567318 | trans-N-(5-(3-(fluoromethoxy)phenyl...)Show SMILES FCOc1cccc(c1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)nc1 |r,wU:19.23,wD:16.16,(32.2,-20.58,;30.87,-21.36,;29.53,-20.59,;28.2,-21.37,;28.21,-22.92,;26.87,-23.69,;25.54,-22.92,;25.54,-21.38,;26.87,-20.61,;24.21,-20.61,;22.87,-21.38,;21.54,-20.61,;21.55,-19.07,;20.21,-18.3,;18.88,-19.07,;17.55,-18.3,;18.88,-20.61,;17.55,-21.39,;17.55,-22.93,;18.88,-23.69,;20.21,-22.93,;20.21,-21.39,;19.8,-24.94,;18.9,-26.2,;19.38,-27.67,;17.42,-25.73,;16.08,-26.5,;14.74,-25.73,;14.74,-24.19,;16.07,-23.42,;17.41,-24.18,;22.87,-18.3,;24.2,-19.06,)| Show InChI InChI=1S/C24H21FN4O4/c25-14-32-18-3-1-2-16(10-18)17-11-27-23(28-12-17)29-21(30)15-4-7-24(8-5-15)20-13-26-9-6-19(20)22(31)33-24/h1-3,6,9-13,15H,4-5,7-8,14H2,(H,27,28,29,30)/t15-,24- | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301662
(CHEMBL584815 | trans-N-(5-(2-(fluoromethyl)phenyl)...)Show SMILES FCc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)nc1 |r,wU:18.22,wD:15.15,(4.61,-32.36,;3.28,-33.13,;3.28,-34.67,;4.62,-35.43,;4.62,-36.98,;3.29,-37.75,;1.96,-36.99,;1.96,-35.44,;.62,-34.68,;-.71,-35.45,;-2.04,-34.68,;-2.03,-33.14,;-3.37,-32.37,;-4.7,-33.14,;-6.04,-32.37,;-4.7,-34.68,;-6.03,-35.45,;-6.03,-36.99,;-4.7,-37.76,;-3.37,-36.99,;-3.37,-35.45,;-3.78,-39.01,;-4.69,-40.27,;-4.2,-41.73,;-6.16,-39.8,;-7.51,-40.57,;-8.84,-39.8,;-8.84,-38.25,;-7.51,-37.48,;-6.17,-38.24,;-.71,-32.36,;.62,-33.13,)| Show InChI InChI=1S/C24H21FN4O3/c25-11-16-3-1-2-4-18(16)17-12-27-23(28-13-17)29-21(30)15-5-8-24(9-6-15)20-14-26-10-7-19(20)22(31)32-24/h1-4,7,10,12-15H,5-6,8-9,11H2,(H,27,28,29,30)/t15-,24- | KEGG
UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301651
(CHEMBL568370 | trans-3'-oxo-N-(5-phenylpyrimidin-2...)Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1cnccc21 |r,wU:18.23,wD:15.16,(26.14,-22.21,;26.91,-23.55,;28.45,-23.55,;29.28,-24.84,;28.58,-26.21,;29.41,-27.5,;30.95,-27.43,;31.65,-26.05,;30.81,-24.76,;31.79,-28.72,;31.08,-30.09,;31.92,-31.38,;33.46,-31.3,;34.16,-29.92,;33.32,-28.63,;26.13,-24.88,;24.59,-24.88,;23.82,-26.21,;24.59,-27.54,;26.13,-27.54,;26.9,-26.21,;25.51,-28.8,;24.6,-30.05,;25.08,-31.52,;23.13,-29.58,;21.79,-30.35,;20.46,-29.58,;20.46,-28.03,;21.79,-27.26,;23.12,-28.02,)| Show InChI InChI=1S/C23H20N4O3/c28-20(27-22-25-12-17(13-26-22)15-4-2-1-3-5-15)16-6-9-23(10-7-16)19-8-11-24-14-18(19)21(29)30-23/h1-5,8,11-14,16H,6-7,9-10H2,(H,25,26,27,28)/t16-,23- | KEGG
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| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301644
(CHEMBL568144 | trans-3-Oxo-N-(5-phenylpyrimidin-2-...)Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ncccc21 |r,wU:18.23,wD:15.16,(27.63,5.75,;28.4,4.41,;29.94,4.41,;30.71,3.08,;29.93,1.75,;30.7,.41,;32.24,.41,;33.01,1.75,;32.24,3.08,;33.01,-.92,;32.24,-2.25,;33,-3.58,;34.55,-3.58,;35.32,-2.24,;34.54,-.91,;27.63,3.08,;26.09,3.08,;25.31,1.75,;26.09,.42,;27.63,.42,;28.39,1.75,;27.01,-.84,;26.09,-2.09,;26.57,-3.56,;24.62,-1.61,;23.29,-2.39,;21.95,-1.61,;21.95,-.07,;23.28,.7,;24.62,-.06,)| Show InChI InChI=1S/C23H20N4O3/c28-20(27-22-25-13-17(14-26-22)15-5-2-1-3-6-15)16-8-10-23(11-9-16)18-7-4-12-24-19(18)21(29)30-23/h1-7,12-14,16H,8-11H2,(H,25,26,27,28)/t16-,23- | KEGG
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| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301654
(CHEMBL565624 | trans-N-(5-(2-(fluoromethoxy)phenyl...)Show SMILES FCOc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:19.23,wD:16.16,(4.33,-24.22,;2.99,-23.45,;1.66,-24.23,;1.67,-25.77,;3,-26.53,;3.01,-28.08,;1.67,-28.85,;.34,-28.08,;.34,-26.54,;-.99,-25.77,;-2.33,-26.54,;-3.66,-25.77,;-3.65,-24.23,;-4.99,-23.46,;-6.32,-24.23,;-7.65,-23.46,;-6.32,-25.77,;-7.65,-26.55,;-7.65,-28.09,;-6.32,-28.85,;-4.99,-28.09,;-4.99,-26.55,;-5.4,-30.1,;-6.3,-31.36,;-5.82,-32.82,;-7.78,-30.89,;-9.12,-31.66,;-10.46,-30.89,;-10.46,-29.35,;-9.13,-28.57,;-7.79,-29.34,;-2.33,-23.46,;-1,-24.22,)| Show InChI InChI=1S/C24H21FN4O4/c25-14-32-20-4-2-1-3-17(20)16-11-27-23(28-12-16)29-21(30)15-5-8-24(9-6-15)19-7-10-26-13-18(19)22(31)33-24/h1-4,7,10-13,15H,5-6,8-9,14H2,(H,27,28,29,30)/t15-,24- | KEGG
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| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301653
(CHEMBL583007 | trans-N-(5-(4-fluorophenyl)pyrimidi...)Show SMILES Fc1ccc(cc1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:17.21,wD:14.14,(33,-12.26,;31.67,-11.49,;30.33,-12.27,;29,-11.5,;29,-9.96,;30.33,-9.18,;31.66,-9.95,;27.67,-9.19,;26.33,-9.96,;25,-9.19,;25.01,-7.65,;23.68,-6.88,;22.34,-7.65,;21.01,-6.88,;22.34,-9.19,;21.01,-9.97,;21.01,-11.51,;22.34,-12.27,;23.67,-11.51,;23.67,-9.97,;23.26,-13.52,;22.36,-14.78,;22.84,-16.24,;20.88,-14.31,;19.54,-15.08,;18.2,-14.31,;18.21,-12.76,;19.53,-11.99,;20.87,-12.76,;26.33,-6.88,;27.66,-7.64,)| Show InChI InChI=1S/C23H19FN4O3/c24-17-3-1-14(2-4-17)16-11-26-22(27-12-16)28-20(29)15-5-8-23(9-6-15)19-7-10-25-13-18(19)21(30)31-23/h1-4,7,10-13,15H,5-6,8-9H2,(H,26,27,28,29)/t15-,23- | KEGG
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| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301646
(CHEMBL584902 | trans-N-(5-(3-fluorophenyl)pyrimidi...)Show SMILES Fc1cccc(c1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ncccc32)nc1 |r,wU:17.21,wD:14.14,(29.51,-9.71,;28.18,-10.49,;28.18,-12.04,;26.85,-12.81,;25.52,-12.04,;25.52,-10.5,;26.84,-9.73,;24.18,-9.73,;22.85,-10.5,;21.52,-9.73,;21.52,-8.19,;20.19,-7.42,;18.86,-8.19,;17.52,-7.42,;18.86,-9.73,;17.53,-10.51,;17.53,-12.05,;18.86,-12.81,;20.19,-12.05,;20.19,-10.51,;19.78,-14.06,;18.87,-15.32,;19.36,-16.78,;17.39,-14.85,;16.05,-15.62,;14.72,-14.85,;14.72,-13.31,;16.05,-12.54,;17.38,-13.3,;22.85,-7.42,;24.18,-8.18,)| Show InChI InChI=1S/C23H19FN4O3/c24-17-4-1-3-15(11-17)16-12-26-22(27-13-16)28-20(29)14-6-8-23(9-7-14)18-5-2-10-25-19(18)21(30)31-23/h1-5,10-14H,6-9H2,(H,26,27,28,29)/t14-,23- | KEGG
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| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301650
(CHEMBL584732 | trans-N-(5-(3-(fluoromethyl)phenyl)...)Show SMILES FCc1cccc(c1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ncccc32)nc1 |r,wU:18.22,wD:15.15,(31.96,-37.33,;30.62,-36.56,;29.29,-37.34,;29.3,-38.89,;27.96,-39.66,;26.63,-38.89,;26.63,-37.35,;27.95,-36.58,;25.3,-36.58,;23.96,-37.35,;22.63,-36.58,;22.64,-35.04,;21.3,-34.27,;19.97,-35.04,;18.64,-34.27,;19.97,-36.58,;18.64,-37.36,;18.64,-38.9,;19.97,-39.66,;21.3,-38.9,;21.3,-37.36,;20.89,-40.91,;19.98,-42.17,;20.47,-43.63,;18.51,-41.7,;17.17,-42.47,;15.83,-41.7,;15.83,-40.16,;17.16,-39.39,;18.5,-40.15,;23.96,-34.27,;25.29,-35.03,)| Show InChI InChI=1S/C24H21FN4O3/c25-12-15-3-1-4-17(11-15)18-13-27-23(28-14-18)29-21(30)16-6-8-24(9-7-16)19-5-2-10-26-20(19)22(31)32-24/h1-5,10-11,13-14,16H,6-9,12H2,(H,27,28,29,30)/t16-,24- | KEGG
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| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301660
(CHEMBL565826 | trans-N-(5-(2-(fluoromethoxy)phenyl...)Show SMILES FCOc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)nc1 |r,wU:19.23,wD:16.16,(4.65,-20.86,;3.32,-20.09,;1.99,-20.87,;1.99,-22.41,;3.33,-23.17,;3.33,-24.72,;2,-25.49,;.67,-24.72,;.67,-23.18,;-.67,-22.41,;-2,-23.18,;-3.33,-22.41,;-3.33,-20.87,;-4.66,-20.1,;-5.99,-20.87,;-7.33,-20.1,;-5.99,-22.41,;-7.32,-23.19,;-7.32,-24.73,;-5.99,-25.49,;-4.66,-24.73,;-4.66,-23.19,;-5.07,-26.74,;-5.98,-28,;-5.49,-29.46,;-7.46,-27.53,;-8.8,-28.3,;-10.13,-27.53,;-10.13,-25.99,;-8.8,-25.21,;-7.47,-25.98,;-2,-20.1,;-.67,-20.86,)| Show InChI InChI=1S/C24H21FN4O4/c25-14-32-20-4-2-1-3-17(20)16-11-27-23(28-12-16)29-21(30)15-5-8-24(9-6-15)19-13-26-10-7-18(19)22(31)33-24/h1-4,7,10-13,15H,5-6,8-9,14H2,(H,27,28,29,30)/t15-,24- | KEGG
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| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301659
(CHEMBL565626 | trans-N-(5-(4-fluorophenyl)pyrimidi...)Show SMILES Fc1ccc(cc1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)nc1 |r,wU:17.21,wD:14.14,(28.38,-12.37,;27.05,-11.6,;25.71,-12.37,;24.38,-11.61,;24.38,-10.06,;25.71,-9.29,;27.04,-10.05,;23.05,-9.3,;21.71,-10.07,;20.38,-9.3,;20.39,-7.76,;19.06,-6.99,;17.72,-7.76,;16.39,-6.99,;17.72,-9.3,;16.39,-10.08,;16.39,-11.62,;17.72,-12.38,;19.05,-11.62,;19.05,-10.08,;18.64,-13.63,;17.74,-14.89,;18.22,-16.35,;16.26,-14.42,;14.92,-15.19,;13.58,-14.42,;13.59,-12.87,;14.91,-12.1,;16.25,-12.87,;21.71,-6.99,;23.04,-7.75,)| Show InChI InChI=1S/C23H19FN4O3/c24-17-3-1-14(2-4-17)16-11-26-22(27-12-16)28-20(29)15-5-8-23(9-6-15)19-13-25-10-7-18(19)21(30)31-23/h1-4,7,10-13,15H,5-6,8-9H2,(H,26,27,28,29)/t15-,23- | KEGG
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| n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301641
(CHEMBL585851 | trans-3-Oxo-N-(5-phenylpyrimidin-2-...)Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1cccnc21 |r,wU:18.23,wD:15.16,(27.76,-36.84,;28.53,-38.18,;30.07,-38.18,;30.88,-39.49,;30.15,-40.84,;30.96,-42.15,;32.5,-42.1,;33.22,-40.74,;32.41,-39.43,;33.31,-43.4,;32.58,-44.76,;33.39,-46.07,;34.93,-46.02,;35.66,-44.65,;34.84,-43.35,;27.76,-39.51,;26.22,-39.51,;25.44,-40.84,;26.22,-42.17,;27.76,-42.17,;28.52,-40.84,;27.14,-43.43,;26.23,-44.68,;26.7,-46.15,;24.75,-44.21,;23.42,-44.98,;22.08,-44.21,;22.09,-42.66,;23.42,-41.89,;24.75,-42.65,)| Show InChI InChI=1S/C23H20N4O3/c28-20(27-22-25-13-17(14-26-22)15-5-2-1-3-6-15)16-8-10-23(11-9-16)19-18(21(29)30-23)7-4-12-24-19/h1-7,12-14,16H,8-11H2,(H,25,26,27,28)/t16-,23- | KEGG
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UniChem
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PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301645
(CHEMBL565848 | trans-N-(5-(2-fluorophenyl)pyrimidi...)Show SMILES Fc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ncccc32)nc1 |r,wU:17.21,wD:14.14,(2.35,-6.74,;2.36,-8.28,;3.69,-9.04,;3.7,-10.59,;2.36,-11.36,;1.03,-10.6,;1.03,-9.05,;-.3,-8.29,;-1.64,-9.06,;-2.97,-8.29,;-2.96,-6.75,;-4.29,-5.98,;-5.63,-6.75,;-6.96,-5.98,;-5.63,-8.29,;-6.96,-9.06,;-6.96,-10.6,;-5.63,-11.37,;-4.3,-10.6,;-4.3,-9.06,;-4.71,-12.62,;-5.61,-13.88,;-5.13,-15.34,;-7.09,-13.41,;-8.43,-14.18,;-9.77,-13.41,;-9.76,-11.86,;-8.43,-11.09,;-7.1,-11.85,;-1.64,-5.97,;-.31,-6.74,)| Show InChI InChI=1S/C23H19FN4O3/c24-18-6-2-1-4-16(18)15-12-26-22(27-13-15)28-20(29)14-7-9-23(10-8-14)17-5-3-11-25-19(17)21(30)31-23/h1-6,11-14H,7-10H2,(H,26,27,28,29)/t14-,23- | KEGG
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PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301649
(CHEMBL565625 | trans-N-(5-(3-(fluoromethoxy)phenyl...)Show SMILES FCOc1cccc(c1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ncccc32)nc1 |r,wU:19.23,wD:16.16,(8.86,-35.8,;7.53,-36.58,;6.2,-35.82,;4.87,-36.59,;4.87,-38.14,;3.54,-38.91,;2.21,-38.14,;2.21,-36.6,;3.53,-35.83,;.87,-35.83,;-.46,-36.6,;-1.79,-35.83,;-1.79,-34.3,;-3.12,-33.53,;-4.45,-34.3,;-5.79,-33.53,;-4.45,-35.84,;-5.78,-36.61,;-5.78,-38.15,;-4.45,-38.92,;-3.12,-38.15,;-3.12,-36.61,;-3.53,-40.16,;-4.44,-41.43,;-3.95,-42.89,;-5.92,-40.95,;-7.26,-41.73,;-8.59,-40.95,;-8.59,-39.41,;-7.26,-38.64,;-5.93,-39.4,;-.46,-33.52,;.87,-34.29,)| Show InChI InChI=1S/C24H21FN4O4/c25-14-32-18-4-1-3-16(11-18)17-12-27-23(28-13-17)29-21(30)15-6-8-24(9-7-15)19-5-2-10-26-20(19)22(31)33-24/h1-5,10-13,15H,6-9,14H2,(H,27,28,29,30)/t15-,24- | KEGG
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301648
(CHEMBL585854 | trans-N-(5-(2-(fluoromethoxy)phenyl...)Show SMILES FCOc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ncccc32)nc1 |r,wU:19.23,wD:16.16,(31.28,-20.74,;29.94,-19.97,;28.61,-20.75,;28.62,-22.29,;29.95,-23.05,;29.96,-24.6,;28.62,-25.37,;27.29,-24.6,;27.29,-23.06,;25.96,-22.29,;24.62,-23.06,;23.29,-22.29,;23.3,-20.75,;21.96,-19.98,;20.63,-20.75,;19.3,-19.98,;20.63,-22.29,;19.3,-23.07,;19.3,-24.61,;20.63,-25.37,;21.96,-24.61,;21.96,-23.07,;21.55,-26.62,;20.65,-27.88,;21.13,-29.35,;19.17,-27.41,;17.83,-28.18,;16.49,-27.41,;16.49,-25.87,;17.82,-25.1,;19.16,-25.86,;24.62,-19.98,;25.95,-20.74,)| Show InChI InChI=1S/C24H21FN4O4/c25-14-32-19-6-2-1-4-17(19)16-12-27-23(28-13-16)29-21(30)15-7-9-24(10-8-15)18-5-3-11-26-20(18)22(31)33-24/h1-6,11-13,15H,7-10,14H2,(H,27,28,29,30)/t15-,24- | KEGG
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| n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301647
(CHEMBL568337 | trans-N-(5-(4-fluorophenyl)pyrimidi...)Show SMILES Fc1ccc(cc1)-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ncccc32)nc1 |r,wU:17.21,wD:14.14,(5.59,-24.52,;4.26,-23.75,;2.92,-24.52,;1.59,-23.76,;1.59,-22.21,;2.92,-21.44,;4.25,-22.2,;.26,-21.45,;-1.08,-22.22,;-2.41,-21.45,;-2.4,-19.91,;-3.73,-19.14,;-5.07,-19.91,;-6.4,-19.14,;-5.07,-21.45,;-6.4,-22.22,;-6.4,-23.76,;-5.07,-24.53,;-3.74,-23.76,;-3.74,-22.22,;-4.15,-25.78,;-5.05,-27.04,;-4.57,-28.5,;-6.53,-26.57,;-7.87,-27.34,;-9.21,-26.57,;-9.2,-25.02,;-7.87,-24.25,;-6.54,-25.01,;-1.08,-19.13,;.25,-19.9,)| Show InChI InChI=1S/C23H19FN4O3/c24-17-5-3-14(4-6-17)16-12-26-22(27-13-16)28-20(29)15-7-9-23(10-8-15)18-2-1-11-25-19(18)21(30)31-23/h1-6,11-13,15H,7-10H2,(H,26,27,28,29)/t15-,23- | KEGG
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| n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50301642
(CHEMBL567495 | trans-N-(5-(2-fluorophenyl)pyrimidi...)Show SMILES Fc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:17.21,wD:14.14,(31.68,5.18,;31.69,3.64,;33.02,2.88,;33.03,1.33,;31.69,.56,;30.36,1.33,;30.36,2.87,;29.03,3.64,;27.69,2.87,;26.36,3.64,;26.37,5.18,;25.04,5.95,;23.7,5.18,;22.37,5.95,;23.7,3.64,;22.37,2.86,;22.37,1.32,;23.7,.56,;25.03,1.32,;25.03,2.86,;24.62,-.69,;23.72,-1.95,;24.2,-3.41,;22.24,-1.48,;20.9,-2.25,;19.56,-1.48,;19.57,.06,;20.9,.83,;22.23,.07,;27.69,5.95,;29.02,5.19,)| Show InChI InChI=1S/C23H19FN4O3/c24-19-4-2-1-3-16(19)15-11-26-22(27-12-15)28-20(29)14-5-8-23(9-6-14)18-7-10-25-13-17(18)21(30)31-23/h1-4,7,10-14H,5-6,8-9H2,(H,26,27,28,29)/t14-,23- | PDB
Reactome pathway
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human NPY Y2 receptor |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50301642
(CHEMBL567495 | trans-N-(5-(2-fluorophenyl)pyrimidi...)Show SMILES Fc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:17.21,wD:14.14,(31.68,5.18,;31.69,3.64,;33.02,2.88,;33.03,1.33,;31.69,.56,;30.36,1.33,;30.36,2.87,;29.03,3.64,;27.69,2.87,;26.36,3.64,;26.37,5.18,;25.04,5.95,;23.7,5.18,;22.37,5.95,;23.7,3.64,;22.37,2.86,;22.37,1.32,;23.7,.56,;25.03,1.32,;25.03,2.86,;24.62,-.69,;23.72,-1.95,;24.2,-3.41,;22.24,-1.48,;20.9,-2.25,;19.56,-1.48,;19.57,.06,;20.9,.83,;22.23,.07,;27.69,5.95,;29.02,5.19,)| Show InChI InChI=1S/C23H19FN4O3/c24-19-4-2-1-3-16(19)15-11-26-22(27-12-15)28-20(29)14-5-8-23(9-6-14)18-7-10-25-13-17(18)21(30)31-23/h1-4,7,10-14H,5-6,8-9H2,(H,26,27,28,29)/t14-,23- | PDB
Reactome pathway
KEGG
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UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human NPY Y1 receptor |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50301642
(CHEMBL567495 | trans-N-(5-(2-fluorophenyl)pyrimidi...)Show SMILES Fc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2cnccc32)nc1 |r,wU:17.21,wD:14.14,(31.68,5.18,;31.69,3.64,;33.02,2.88,;33.03,1.33,;31.69,.56,;30.36,1.33,;30.36,2.87,;29.03,3.64,;27.69,2.87,;26.36,3.64,;26.37,5.18,;25.04,5.95,;23.7,5.18,;22.37,5.95,;23.7,3.64,;22.37,2.86,;22.37,1.32,;23.7,.56,;25.03,1.32,;25.03,2.86,;24.62,-.69,;23.72,-1.95,;24.2,-3.41,;22.24,-1.48,;20.9,-2.25,;19.56,-1.48,;19.57,.06,;20.9,.83,;22.23,.07,;27.69,5.95,;29.02,5.19,)| Show InChI InChI=1S/C23H19FN4O3/c24-19-4-2-1-3-16(19)15-11-26-22(27-12-15)28-20(29)14-5-8-23(9-6-14)18-7-10-25-13-17(18)21(30)31-23/h1-4,7,10-14H,5-6,8-9H2,(H,26,27,28,29)/t14-,23- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human NPY Y4 receptor |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103
BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this
Ligand-Target Pair | |
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