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PubMed code 25900219

Compile data set for download or QSAR
Found 54 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069751
PNG
(CHEMBL2356114)
Show SMILES C[C@@H](N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc2OCOc2c1)C(=O)NC1CCCC1
Show InChI InChI=1S/C24H32N6O4/c1-16(24(32)25-18-7-5-6-8-18)30(19-9-3-2-4-10-19)22(31)14-29-27-23(26-28-29)17-11-12-20-21(13-17)34-15-33-20/h11-13,16,18-19H,2-10,14-15H2,1H3,(H,25,32)/t16-/m1/s1
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n/an/a 5n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid sci...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069719
PNG
(CHEMBL2358771)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)C3CCCCC3)cc2C1=O
Show InChI InChI=1S/C29H38ClN3O6S/c1-19-16-33(20(2)18-34)29(36)25-15-23(31-28(35)21-7-5-4-6-8-21)11-14-26(25)39-27(19)17-32(3)40(37,38)24-12-9-22(30)10-13-24/h9-15,19-21,27,34H,4-8,16-18H2,1-3H3,(H,31,35)/t19-,20-,27+/m1/s1
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n/an/a 54n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069697
PNG
(CHEMBL2356172)
Show SMILES CC(C)NC(=O)Nc1ccc2O[C@@H](CN(C)S(=O)(=O)c3ccc(Cl)cc3)[C@H](C)CN([C@H](C)CO)C(=O)c2c1
Show InChI InChI=1S/C26H35ClN4O6S/c1-16(2)28-26(34)29-20-8-11-23-22(12-20)25(33)31(18(4)15-32)13-17(3)24(37-23)14-30(5)38(35,36)21-9-6-19(27)7-10-21/h6-12,16-18,24,32H,13-15H2,1-5H3,(H2,28,29,34)/t17-,18-,24+/m1/s1
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Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069714
PNG
(CHEMBL2356554)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Nc3ccc(F)cc3)cc2C1=O
Show InChI InChI=1S/C29H32ClFN4O6S/c1-18-15-35(19(2)17-36)28(37)25-14-23(33-29(38)32-22-8-6-21(31)7-9-22)10-13-26(25)41-27(18)16-34(3)42(39,40)24-11-4-20(30)5-12-24/h4-14,18-19,27,36H,15-17H2,1-3H3,(H2,32,33,38)/t18-,19-,27+/m1/s1
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n/an/a 92n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069703
PNG
(CHEMBL2361909)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccccc2Cl)Oc2ccc(NC(=O)C3CCCCC3)cc2C1=O
Show InChI InChI=1S/C29H38ClN3O6S/c1-19-16-33(20(2)18-34)29(36)23-15-22(31-28(35)21-9-5-4-6-10-21)13-14-25(23)39-26(19)17-32(3)40(37,38)27-12-8-7-11-24(27)30/h7-8,11-15,19-21,26,34H,4-6,9-10,16-18H2,1-3H3,(H,31,35)/t19-,20-,26+/m1/s1
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n/an/a 180n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069750
PNG
(CHEMBL2357128)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O
Show InChI InChI=1S/C33H37ClN4O6S/c1-21-17-38(22(2)20-39)33(41)28-16-25(35-32(40)15-23-18-36(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)19-37(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,18,21-22,31,39H,15,17,19-20H2,1-4H3,(H,35,40)/t21-,22-,31+/m1/s1
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n/an/a 180n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069707
PNG
(CHEMBL2362430)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NS(=O)(=O)c3c(C)noc3C)cc2C1=O
Show InChI InChI=1S/C27H33ClN4O8S2/c1-16-13-32(17(2)15-33)27(34)23-12-21(30-41(35,36)26-18(3)29-40-19(26)4)8-11-24(23)39-25(16)14-31(5)42(37,38)22-9-6-20(28)7-10-22/h6-12,16-17,25,30,33H,13-15H2,1-5H3/t16-,17-,25+/m1/s1
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n/an/a 190n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069741
PNG
(CHEMBL3400863)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccccc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C33H38N4O6S/c1-22-18-37(23(2)21-38)33(40)28-17-25(34-32(39)16-24-19-35(3)29-13-9-8-12-27(24)29)14-15-30(28)43-31(22)20-36(4)44(41,42)26-10-6-5-7-11-26/h5-15,17,19,22-23,31,38H,16,18,20-21H2,1-4H3,(H,34,39)/t22-,23-,31+/m1/s1
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Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069697
PNG
(CHEMBL2356172)
Show SMILES CC(C)NC(=O)Nc1ccc2O[C@@H](CN(C)S(=O)(=O)c3ccc(Cl)cc3)[C@H](C)CN([C@H](C)CO)C(=O)c2c1
Show InChI InChI=1S/C26H35ClN4O6S/c1-16(2)28-26(34)29-20-8-11-23-22(12-20)25(33)31(18(4)15-32)13-17(3)24(37-23)14-30(5)38(35,36)21-9-6-19(27)7-10-21/h6-12,16-18,24,32H,13-15H2,1-5H3,(H2,28,29,34)/t17-,18-,24+/m1/s1
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n/an/a 250n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid sci...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069722
PNG
(CHEMBL3400876)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)CCC(F)(F)F)cc2C1=O |r|
Show InChI InChI=1S/C26H31ClF3N3O6S/c1-16-13-33(17(2)15-34)25(36)21-12-19(31-24(35)10-11-26(28,29)30)6-9-22(21)39-23(16)14-32(3)40(37,38)20-7-4-18(27)5-8-20/h4-9,12,16-17,23,34H,10-11,13-15H2,1-3H3,(H,31,35)/t16-,17-,23+/m1/s1
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n/an/a 260n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069713
PNG
(CHEMBL3400882)
Show SMILES COc1ccc(NC(=O)Nc2ccc3O[C@@H](CN(C)S(=O)(=O)c4ccc(Cl)cc4)[C@H](C)CN([C@H](C)CO)C(=O)c3c2)cc1 |r|
Show InChI InChI=1S/C30H35ClN4O7S/c1-19-16-35(20(2)18-36)29(37)26-15-23(33-30(38)32-22-7-10-24(41-4)11-8-22)9-14-27(26)42-28(19)17-34(3)43(39,40)25-12-5-21(31)6-13-25/h5-15,19-20,28,36H,16-18H2,1-4H3,(H2,32,33,38)/t19-,20-,28+/m1/s1
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Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069711
PNG
(CHEMBL2356546)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)NC3CCCCC3)cc2C1=O
Show InChI InChI=1S/C29H39ClN4O6S/c1-19-16-34(20(2)18-35)28(36)25-15-23(32-29(37)31-22-7-5-4-6-8-22)11-14-26(25)40-27(19)17-33(3)41(38,39)24-12-9-21(30)10-13-24/h9-15,19-20,22,27,35H,4-8,16-18H2,1-3H3,(H2,31,32,37)/t19-,20-,27+/m1/s1
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Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069743
PNG
(CHEMBL1710685)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(F)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O
Show InChI InChI=1S/C33H37FN4O6S/c1-21-17-38(22(2)20-39)33(41)28-16-25(35-32(40)15-23-18-36(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)19-37(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,18,21-22,31,39H,15,17,19-20H2,1-4H3,(H,35,40)/t21-,22-,31+/m1/s1
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Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069702
PNG
(CHEMBL3402562)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(cc2C1=O)N(C)C |r|
Show InChI InChI=1S/C24H32ClN3O5S/c1-16-13-28(17(2)15-29)24(30)21-12-19(26(3)4)8-11-22(21)33-23(16)14-27(5)34(31,32)20-9-6-18(25)7-10-20/h6-12,16-17,23,29H,13-15H2,1-5H3/t16-,17-,23+/m1/s1
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n/an/a 630n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069726
PNG
(CHEMBL2359464)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)Cc2ccc(cc2)C(F)(F)F)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O
Show InChI InChI=1S/C35H39F3N4O4/c1-22-17-42(23(2)21-43)34(45)29-16-27(39-33(44)15-25-19-41(4)30-8-6-5-7-28(25)30)13-14-31(29)46-32(22)20-40(3)18-24-9-11-26(12-10-24)35(36,37)38/h5-14,16,19,22-23,32,43H,15,17-18,20-21H2,1-4H3,(H,39,44)/t22-,23-,32+/m1/s1
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n/an/a 650n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50323654
PNG
(CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...)
Show SMILES COc1c(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C
Show InChI InChI=1S/C30H37N3O7S/c1-30(2,3)20-18-24(28(38-4)25(19-20)32-41(5,36)37)31-29(35)27(34)23-10-11-26(22-9-7-6-8-21(22)23)40-17-14-33-12-15-39-16-13-33/h6-11,18-19,32H,12-17H2,1-5H3,(H,31,35)
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n/an/a 770n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid sci...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069704
PNG
(CHEMBL2362877)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2cccc(Cl)c2)Oc2ccc(NC(=O)C3CCCCC3)cc2C1=O
Show InChI InChI=1S/C29H38ClN3O6S/c1-19-16-33(20(2)18-34)29(36)25-15-23(31-28(35)21-8-5-4-6-9-21)12-13-26(25)39-27(19)17-32(3)40(37,38)24-11-7-10-22(30)14-24/h7,10-15,19-21,27,34H,4-6,8-9,16-18H2,1-3H3,(H,31,35)/t19-,20-,27+/m1/s1
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n/an/a>800n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069724
PNG
(CHEMBL3400874)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)Cc2ccc3OCOc3c2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C35H40N4O6/c1-22-16-39(23(2)20-40)35(42)28-15-26(36-34(41)14-25-18-38(4)29-8-6-5-7-27(25)29)10-12-30(28)45-33(22)19-37(3)17-24-9-11-31-32(13-24)44-21-43-31/h5-13,15,18,22-23,33,40H,14,16-17,19-21H2,1-4H3,(H,36,41)/t22-,23-,33+/m1/s1
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n/an/a 890n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069747
PNG
(CHEMBL3400860)
Show SMILES C[C@@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C33H37ClN4O6S/c1-21-17-38(22(2)20-39)33(41)28-16-25(35-32(40)15-23-18-36(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)19-37(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,18,21-22,31,39H,15,17,19-20H2,1-4H3,(H,35,40)/t21-,22+,31+/m1/s1
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n/an/a 910n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069723
PNG
(CHEMBL3400875)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)Cc2ccncc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C33H39N5O4/c1-22-17-38(23(2)21-39)33(41)28-16-26(35-32(40)15-25-19-37(4)29-8-6-5-7-27(25)29)9-10-30(28)42-31(22)20-36(3)18-24-11-13-34-14-12-24/h5-14,16,19,22-23,31,39H,15,17-18,20-21H2,1-4H3,(H,35,40)/t22-,23-,31+/m1/s1
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n/an/a 1.30E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069710
PNG
(CHEMBL3402559)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NS(C)(=O)=O)cc2C1=O |r|
Show InChI InChI=1S/C23H30ClN3O7S2/c1-15-12-27(16(2)14-28)23(29)20-11-18(25-35(4,30)31)7-10-21(20)34-22(15)13-26(3)36(32,33)19-8-5-17(24)6-9-19/h5-11,15-16,22,25,28H,12-14H2,1-4H3/t15-,16-,22+/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069728
PNG
(CHEMBL3400872)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)Cc2ccccc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C34H40N4O4/c1-23-18-38(24(2)22-39)34(41)29-17-27(35-33(40)16-26-20-37(4)30-13-9-8-12-28(26)30)14-15-31(29)42-32(23)21-36(3)19-25-10-6-5-7-11-25/h5-15,17,20,23-24,32,39H,16,18-19,21-22H2,1-4H3,(H,35,40)/t23-,24-,32+/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069742
PNG
(CHEMBL3400862)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(C)C[C@@H]1Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C(=O)N(C[C@H]1C)[C@H](C)CO |r|
Show InChI InChI=1S/C34H40N4O7S/c1-22-18-38(23(2)21-39)34(41)29-17-25(35-33(40)16-24-19-36(3)30-9-7-6-8-28(24)30)10-15-31(29)45-32(22)20-37(4)46(42,43)27-13-11-26(44-5)12-14-27/h6-15,17,19,22-23,32,39H,16,18,20-21H2,1-5H3,(H,35,40)/t22-,23-,32+/m1/s1
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n/an/a 2.00E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069717
PNG
(CHEMBL3400879)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)C3CC3)cc2C1=O |r|
Show InChI InChI=1S/C26H32ClN3O6S/c1-16-13-30(17(2)15-31)26(33)22-12-20(28-25(32)18-4-5-18)8-11-23(22)36-24(16)14-29(3)37(34,35)21-9-6-19(27)7-10-21/h6-12,16-18,24,31H,4-5,13-15H2,1-3H3,(H,28,32)/t16-,17-,24+/m1/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069740
PNG
(CHEMBL3400864)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2cccs2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C31H36N4O6S2/c1-20-16-35(21(2)19-36)31(38)25-15-23(32-29(37)14-22-17-33(3)26-9-6-5-8-24(22)26)11-12-27(25)41-28(20)18-34(4)43(39,40)30-10-7-13-42-30/h5-13,15,17,20-21,28,36H,14,16,18-19H2,1-4H3,(H,32,37)/t20-,21-,28+/m1/s1
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n/an/a 2.40E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069727
PNG
(CHEMBL3400873)
Show SMILES COc1ccc(CN(C)C[C@@H]2Oc3ccc(NC(=O)Cc4cn(C)c5ccccc45)cc3C(=O)N(C[C@H]2C)[C@H](C)CO)cc1 |r|
Show InChI InChI=1S/C35H42N4O5/c1-23-18-39(24(2)22-40)35(42)30-17-27(36-34(41)16-26-20-38(4)31-9-7-6-8-29(26)31)12-15-32(30)44-33(23)21-37(3)19-25-10-13-28(43-5)14-11-25/h6-15,17,20,23-24,33,40H,16,18-19,21-22H2,1-5H3,(H,36,41)/t23-,24-,33+/m1/s1
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n/an/a 2.60E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069709
PNG
(CHEMBL3402560)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NS(=O)(=O)c3ccccc3)cc2C1=O |r|
Show InChI InChI=1S/C28H32ClN3O7S2/c1-19-16-32(20(2)18-33)28(34)25-15-22(30-40(35,36)23-7-5-4-6-8-23)11-14-26(25)39-27(19)17-31(3)41(37,38)24-12-9-21(29)10-13-24/h4-15,19-20,27,30,33H,16-18H2,1-3H3/t19-,20-,27+/m1/s1
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n/an/a 3.20E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069737
PNG
(CHEMBL3400867)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)C(=O)Nc2ccccc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C34H39N5O5/c1-22-18-39(23(2)21-40)33(42)28-17-26(35-32(41)16-24-19-37(3)29-13-9-8-12-27(24)29)14-15-30(28)44-31(22)20-38(4)34(43)36-25-10-6-5-7-11-25/h5-15,17,19,22-23,31,40H,16,18,20-21H2,1-4H3,(H,35,41)(H,36,43)/t22-,23-,31+/m1/s1
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n/an/a 4.90E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069720
PNG
(CHEMBL3400878)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)CCN3CCOCC3)cc2C1=O |r|
Show InChI InChI=1S/C29H39ClN4O7S/c1-20-17-34(21(2)19-35)29(37)25-16-23(31-28(36)10-11-33-12-14-40-15-13-33)6-9-26(25)41-27(20)18-32(3)42(38,39)24-7-4-22(30)5-8-24/h4-9,16,20-21,27,35H,10-15,17-19H2,1-3H3,(H,31,36)/t20-,21-,27+/m1/s1
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n/an/a 5.00E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069739
PNG
(CHEMBL3400865)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2cn(C)cn2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C31H38N6O6S/c1-20-14-37(21(2)18-38)31(40)25-13-23(33-29(39)12-22-15-35(4)26-9-7-6-8-24(22)26)10-11-27(25)43-28(20)16-36(5)44(41,42)30-17-34(3)19-32-30/h6-11,13,15,17,19-21,28,38H,12,14,16,18H2,1-5H3,(H,33,39)/t20-,21-,28+/m1/s1
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n/an/a 6.40E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069712
PNG
(CHEMBL3402558)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Nc3c(C)noc3C)cc2C1=O |r|
Show InChI InChI=1S/C28H34ClN5O7S/c1-16-13-34(17(2)15-35)27(36)23-12-21(30-28(37)31-26-18(3)32-41-19(26)4)8-11-24(23)40-25(16)14-33(5)42(38,39)22-9-6-20(29)7-10-22/h6-12,16-17,25,35H,13-15H2,1-5H3,(H2,30,31,37)/t16-,17-,25+/m1/s1
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n/an/a 7.10E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069699
PNG
(CHEMBL3402564)
Show SMILES COC[C@@H](C)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)NC(C)C)cc2C1=O |r|
Show InChI InChI=1S/C27H37ClN4O6S/c1-17(2)29-27(34)30-21-9-12-24-23(13-21)26(33)32(19(4)16-37-6)14-18(3)25(38-24)15-31(5)39(35,36)22-10-7-20(28)8-11-22/h7-13,17-19,25H,14-16H2,1-6H3,(H2,29,30,34)/t18-,19-,25+/m1/s1
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n/an/a 8.00E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069749
PNG
(CHEMBL3400858)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C33H37ClN4O6S/c1-21-17-38(22(2)20-39)33(41)28-16-25(35-32(40)15-23-18-36(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)19-37(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,18,21-22,31,39H,15,17,19-20H2,1-4H3,(H,35,40)/t21-,22-,31-/m1/s1
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n/an/a 8.90E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069736
PNG
(CHEMBL3400868)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)C(=O)NC2CCCCC2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C34H45N5O5/c1-22-18-39(23(2)21-40)33(42)28-17-26(35-32(41)16-24-19-37(3)29-13-9-8-12-27(24)29)14-15-30(28)44-31(22)20-38(4)34(43)36-25-10-6-5-7-11-25/h8-9,12-15,17,19,22-23,25,31,40H,5-7,10-11,16,18,20-21H2,1-4H3,(H,35,41)(H,36,43)/t22-,23-,31+/m1/s1
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n/an/a 9.20E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069733
PNG
(CHEMBL3400871)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)CC2CCCCC2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C34H46N4O4/c1-23-18-38(24(2)22-39)34(41)29-17-27(35-33(40)16-26-20-37(4)30-13-9-8-12-28(26)30)14-15-31(29)42-32(23)21-36(3)19-25-10-6-5-7-11-25/h8-9,12-15,17,20,23-25,32,39H,5-7,10-11,16,18-19,21-22H2,1-4H3,(H,35,40)/t23-,24-,32+/m1/s1
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n/an/a 9.20E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069738
PNG
(CHEMBL3400866)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(C)(=O)=O)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C28H36N4O6S/c1-18-14-32(19(2)17-33)28(35)23-13-21(10-11-25(23)38-26(18)16-31(4)39(5,36)37)29-27(34)12-20-15-30(3)24-9-7-6-8-22(20)24/h6-11,13,15,18-19,26,33H,12,14,16-17H2,1-5H3,(H,29,34)/t18-,19-,26+/m1/s1
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n/an/a 9.90E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069698
PNG
(CHEMBL3402565)
Show SMILES CC(C)NC(=O)Nc1ccc2O[C@@H](CN(C)S(=O)(=O)c3ccc(Cl)cc3)[C@H](C)CN(C(C)C)C(=O)c2c1 |r|
Show InChI InChI=1S/C26H35ClN4O5S/c1-16(2)28-26(33)29-20-9-12-23-22(13-20)25(32)31(17(3)4)14-18(5)24(36-23)15-30(6)37(34,35)21-10-7-19(27)8-11-21/h7-13,16-18,24H,14-15H2,1-6H3,(H2,28,29,33)/t18-,24+/m1/s1
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n/an/a 9.90E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069716
PNG
(CHEMBL3400880)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cn3cnnn3)cc2C1=O |r|
Show InChI InChI=1S/C25H30ClN7O6S/c1-16-11-33(17(2)14-34)25(36)21-10-19(28-24(35)13-32-15-27-29-30-32)6-9-22(21)39-23(16)12-31(3)40(37,38)20-7-4-18(26)5-8-20/h4-10,15-17,23,34H,11-14H2,1-3H3,(H,28,35)/t16-,17-,23+/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069744
PNG
(CHEMBL2358270)
Show SMILES C[C@@H](CO)N1C[C@@H](C)[C@@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O
Show InChI InChI=1S/C33H37ClN4O6S/c1-21-17-38(22(2)20-39)33(41)28-16-25(35-32(40)15-23-18-36(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)19-37(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,18,21-22,31,39H,15,17,19-20H2,1-4H3,(H,35,40)/t21-,22+,31-/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069745
PNG
(CHEMBL2133986)
Show SMILES C[C@@H](CO)N1C[C@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O
Show InChI InChI=1S/C33H37ClN4O6S/c1-21-17-38(22(2)20-39)33(41)28-16-25(35-32(40)15-23-18-36(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)19-37(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,18,21-22,31,39H,15,17,19-20H2,1-4H3,(H,35,40)/t21-,22-,31-/m0/s1
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n/an/a 1.23E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069708
PNG
(CHEMBL3402561)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2C1=O |r|
Show InChI InChI=1S/C28H31ClFN3O7S2/c1-18-15-33(19(2)17-34)28(35)25-14-22(31-41(36,37)23-11-6-21(30)7-12-23)8-13-26(25)40-27(18)16-32(3)42(38,39)24-9-4-20(29)5-10-24/h4-14,18-19,27,31,34H,15-17H2,1-3H3/t18-,19-,27+/m1/s1
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n/an/a 1.40E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069746
PNG
(CHEMBL3400861)
Show SMILES C[C@@H](CO)N1C[C@H](C)[C@@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C33H37ClN4O6S/c1-21-17-38(22(2)20-39)33(41)28-16-25(35-32(40)15-23-18-36(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)19-37(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,18,21-22,31,39H,15,17,19-20H2,1-4H3,(H,35,40)/t21-,22-,31+/m0/s1
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n/an/a 1.74E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069734
PNG
(CHEMBL3400870)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)C)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C28H36N4O4/c1-18-14-32(19(2)17-33)28(35)23-13-21(10-11-25(23)36-26(18)16-30(3)4)29-27(34)12-20-15-31(5)24-9-7-6-8-22(20)24/h6-11,13,15,18-19,26,33H,12,14,16-17H2,1-5H3,(H,29,34)/t18-,19-,26+/m1/s1
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n/an/a 1.80E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069718
PNG
(CHEMBL2354660)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)C3CCOCC3)cc2C1=O
Show InChI InChI=1S/C28H36ClN3O7S/c1-18-15-32(19(2)17-33)28(35)24-14-22(30-27(34)20-10-12-38-13-11-20)6-9-25(24)39-26(18)16-31(3)40(36,37)23-7-4-21(29)5-8-23/h4-9,14,18-20,26,33H,10-13,15-17H2,1-3H3,(H,30,34)/t18-,19-,26+/m1/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069725
PNG
(CHEMBL2361520)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)Cc2ccc(Cl)c(Cl)c2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O
Show InChI InChI=1S/C34H38Cl2N4O4/c1-21-16-40(22(2)20-41)34(43)27-15-25(37-33(42)14-24-18-39(4)30-8-6-5-7-26(24)30)10-12-31(27)44-32(21)19-38(3)17-23-9-11-28(35)29(36)13-23/h5-13,15,18,21-22,32,41H,14,16-17,19-20H2,1-4H3,(H,37,42)/t21-,22-,32+/m1/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069735
PNG
(CHEMBL3400869)
Show SMILES CNC[C@@H]1Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C(=O)N(C[C@H]1C)[C@H](C)CO |r|
Show InChI InChI=1S/C27H34N4O4/c1-17-14-31(18(2)16-32)27(34)22-12-20(9-10-24(22)35-25(17)13-28-3)29-26(33)11-19-15-30(4)23-8-6-5-7-21(19)23/h5-10,12,15,17-18,25,28,32H,11,13-14,16H2,1-4H3,(H,29,33)/t17-,18-,25+/m1/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069706
PNG
(CHEMBL2359683)
Show SMILES CC(C)NC(=O)Nc1cccc2c1O[C@@H](CN(C)S(=O)(=O)c1ccc(Cl)cc1)[C@H](C)CN([C@H](C)CO)C2=O
Show InChI InChI=1S/C26H35ClN4O6S/c1-16(2)28-26(34)29-22-8-6-7-21-24(22)37-23(17(3)13-31(25(21)33)18(4)15-32)14-30(5)38(35,36)20-11-9-19(27)10-12-20/h6-12,16-18,23,32H,13-15H2,1-5H3,(H2,28,29,34)/t17-,18-,23+/m1/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069721
PNG
(CHEMBL3400877)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)CCCN(C)C)cc2C1=O |r|
Show InChI InChI=1S/C28H39ClN4O6S/c1-19-16-33(20(2)18-34)28(36)24-15-22(30-27(35)7-6-14-31(3)4)10-13-25(24)39-26(19)17-32(5)40(37,38)23-11-8-21(29)9-12-23/h8-13,15,19-20,26,34H,6-7,14,16-18H2,1-5H3,(H,30,35)/t19-,20-,26+/m1/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069700
PNG
(CHEMBL2360521)
Show SMILES C[C@H](CN(C)C)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O
Show InChI InChI=1S/C35H42ClN5O5S/c1-23-19-41(24(2)20-38(3)4)35(43)30-18-27(37-34(42)17-25-21-39(5)31-10-8-7-9-29(25)31)13-16-32(30)46-33(23)22-40(6)47(44,45)28-14-11-26(36)12-15-28/h7-16,18,21,23-24,33H,17,19-20,22H2,1-6H3,(H,37,42)/t23-,24-,33+/m1/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069705
PNG
(CHEMBL2358493)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)C(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)C3CCCCC3)cc2C1=O
Show InChI InChI=1S/C30H38ClN3O5/c1-19-16-34(20(2)18-35)30(38)25-15-24(32-28(36)21-7-5-4-6-8-21)13-14-26(25)39-27(19)17-33(3)29(37)22-9-11-23(31)12-10-22/h9-15,19-21,27,35H,4-8,16-18H2,1-3H3,(H,32,36)/t19-,20-,27+/m1/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069748
PNG
(CHEMBL3400859)
Show SMILES C[C@H](CO)N1C[C@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C33H37ClN4O6S/c1-21-17-38(22(2)20-39)33(41)28-16-25(35-32(40)15-23-18-36(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)19-37(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,18,21-22,31,39H,15,17,19-20H2,1-4H3,(H,35,40)/t21-,22+,31-/m0/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069701
PNG
(CHEMBL3402563)
Show SMILES C[C@H](CN)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C33H38ClN5O5S/c1-21-18-39(22(2)17-35)33(41)28-16-25(36-32(40)15-23-19-37(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)20-38(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,19,21-22,31H,15,17-18,20,35H2,1-4H3,(H,36,40)/t21-,22-,31+/m1/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069715
PNG
(CHEMBL3400881)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Nc3ccccc3)cc2C1=O |r|
Show InChI InChI=1S/C29H33ClN4O6S/c1-19-16-34(20(2)18-35)28(36)25-15-23(32-29(37)31-22-7-5-4-6-8-22)11-14-26(25)40-27(19)17-33(3)41(38,39)24-12-9-21(30)10-13-24/h4-15,19-20,27,35H,16-18H2,1-3H3,(H2,31,32,37)/t19-,20-,27+/m1/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069697
PNG
(CHEMBL2356172)
Show SMILES CC(C)NC(=O)Nc1ccc2O[C@@H](CN(C)S(=O)(=O)c3ccc(Cl)cc3)[C@H](C)CN([C@H](C)CO)C(=O)c2c1
Show InChI InChI=1S/C26H35ClN4O6S/c1-16(2)28-26(34)29-20-8-11-23-22(12-20)25(33)31(18(4)15-32)13-17(3)24(37-23)14-30(5)38(35,36)21-9-6-19(27)7-10-21/h6-12,16-18,24,32H,13-15H2,1-5H3,(H2,28,29,34)/t17-,18-,24+/m1/s1
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n/an/an/an/a 400n/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of binding of ALexa-488-labeled HDL particles to cells after 3 hrs

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%