Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM11023 ((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM11023 ((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 850 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173580 (N',N'',N'''-(pyridine-2,4,...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM173576 (N',N'',N'''-(pyridine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.56E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
GC University | Assay Description The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM173575 (N',N'',N'''-(pyridine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.68E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
GC University | Assay Description The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM173577 (N',N'',N'''-(pyridine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.88E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
GC University | Assay Description The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173581 (N',N'',N'''-(pyridine-2,4,...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.91E+4 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM173574 (N',N'',N'''-(pyridine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.22E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
GC University | Assay Description The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM23406 ((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3.83E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
GC University | Assay Description The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM173574 (N',N'',N'''-(pyridine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.38E+4 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM173580 (N',N'',N'''-(pyridine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.48E+4 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173574 (N',N'',N'''-(pyridine-2,4,...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.02E+4 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM173581 (N',N'',N'''-(pyridine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.12E+5 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM173578 (N',N'',N'''-(pyridine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
GC University | Assay Description The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM173579 (N',N'',N'''-(pyridine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5.00E+5 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM173582 (N,N',N''-((2,2',2''-(pyrid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5.00E+5 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM173577 (N',N'',N'''-(pyridine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5.00E+5 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM173579 (N',N'',N'''-(pyridine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5.00E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
GC University | Assay Description The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173577 (N',N'',N'''-(pyridine-2,4,...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5.00E+5 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173579 (N',N'',N'''-(pyridine-2,4,...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5.00E+5 | n/a | n/a | n/a | n/a | 7.7 | n/a |
GC University | Assay Description The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b... | Bioorg Chem 63: 64-71 (2015) Article DOI: 10.1016/j.bioorg.2015.09.008 BindingDB Entry DOI: 10.7270/Q2RJ4H7T | |||||||||||
More data for this Ligand-Target Pair |