Affinity Data by PubMed id=26708110

PubMed code 26708110

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Trypanothione reductase (Trypanosoma brucei brucei)	BDBM50142687 (CHEMBL3758404) Show SMILES ClCC(=O)N1c2ccccc2COc2ccc(Cl)cc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Time dependent inhibition of recombinant Trypanosoma brucei trypanothione reductase preincubated with protein for 10 to 180 mins followed by NADPH, t...				Eur J Med Chem 108: 436-43 (2016) Article DOI: 10.1016/j.ejmech.2015.11.023 BindingDB Entry DOI: 10.7270/Q2GH9KTB
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma brucei brucei)	BDBM50142685 (CHEMBL3758242) Show SMILES ClCC(=O)N1c2ccccc2Oc2ccc(Cl)cc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Time dependent inhibition of recombinant Trypanosoma brucei trypanothione reductase preincubated with protein for 10 to 180 mins followed by NADPH, t...				Eur J Med Chem 108: 436-43 (2016) Article DOI: 10.1016/j.ejmech.2015.11.023 BindingDB Entry DOI: 10.7270/Q2GH9KTB
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma brucei brucei)	BDBM50142684 (CHEMBL1651446) Show SMILES ClCC(=O)N1c2ccccc2Sc2ccccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Time dependent inhibition of recombinant Trypanosoma brucei trypanothione reductase preincubated with protein for 10 to 180 mins followed by NADPH, t...				Eur J Med Chem 108: 436-43 (2016) Article DOI: 10.1016/j.ejmech.2015.11.023 BindingDB Entry DOI: 10.7270/Q2GH9KTB
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma brucei brucei)	BDBM50142683 (CHEMBL1801896) Show SMILES Clc1ccc2Oc3ccccc3Nc2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Time dependent inhibition of recombinant Trypanosoma brucei trypanothione reductase preincubated with protein for 10 to 180 mins followed by NADPH, t...				Eur J Med Chem 108: 436-43 (2016) Article DOI: 10.1016/j.ejmech.2015.11.023 BindingDB Entry DOI: 10.7270/Q2GH9KTB
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma brucei brucei)	BDBM50399189 (CHEMBL2180182) Show SMILES CC(=O)N1c2ccccc2Oc2ccccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Time dependent inhibition of recombinant Trypanosoma brucei trypanothione reductase preincubated with protein for 10 to 180 mins followed by NADPH, t...				Eur J Med Chem 108: 436-43 (2016) Article DOI: 10.1016/j.ejmech.2015.11.023 BindingDB Entry DOI: 10.7270/Q2GH9KTB
University of Wuerzburg Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%