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PubMed code 26947609

Compile data set for download or QSAR
Found 25 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157866
PNG
(CHEMBL3785238)
Show SMILES CC1CCN(CCCOc2nc(nc3CCCCc23)-c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C23H30ClN3O/c1-17-11-14-27(15-12-17)13-4-16-28-23-20-5-2-3-6-21(20)25-22(26-23)18-7-9-19(24)10-8-18/h7-10,17H,2-6,11-16H2,1H3
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 16n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for neuronal nicotinic acetylcholine receptor (nAChR) binding in a whole rat brain preparation using [3H]-cystine as the radioligand.

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157867
PNG
(CHEMBL3786384)
Show SMILES CC1CCN(CCCOc2nc(nc3CCCc23)-c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C22H28ClN3O/c1-16-10-13-26(14-11-16)12-3-15-27-22-19-4-2-5-20(19)24-21(25-22)17-6-8-18(23)9-7-17/h6-9,16H,2-5,10-15H2,1H3
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 21n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157858
PNG
(CHEMBL3786154)
Show SMILES CC1CCN(CCCOc2nc(nc3CCCCc23)-c2ccc(C)cc2)CC1
Show InChI InChI=1S/C24H33N3O/c1-18-8-10-20(11-9-18)23-25-22-7-4-3-6-21(22)24(26-23)28-17-5-14-27-15-12-19(2)13-16-27/h8-11,19H,3-7,12-17H2,1-2H3
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 24n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157875
PNG
(CHEMBL3786776)
Show SMILES CC1CCN(CCCOc2nc(nc3CCCCc23)-c2ccccc2)CC1
Show InChI InChI=1S/C23H31N3O/c1-18-12-15-26(16-13-18)14-7-17-27-23-20-10-5-6-11-21(20)24-22(25-23)19-8-3-2-4-9-19/h2-4,8-9,18H,5-7,10-17H2,1H3
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 26n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for functional activity against neuronal nicotinic acetylcholine receptor(nAChR) expressed in K177 cells using isotopic rubidium efflux assay.

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157876
PNG
(CHEMBL3787276)
Show SMILES CN1CCN(CCCOc2nc(nc3CCCCc23)-c2ccccc2)CC1
Show InChI InChI=1S/C22H30N4O/c1-25-13-15-26(16-14-25)12-7-17-27-22-19-10-5-6-11-20(19)23-21(24-22)18-8-3-2-4-9-18/h2-4,8-9H,5-7,10-17H2,1H3
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 27n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157865
PNG
(CHEMBL3786829)
Show SMILES CC1CCN(CCCOc2nc(nc3CCCCc23)-c2ccc(cc2)C(F)(F)F)CC1
Show InChI InChI=1S/C24H30F3N3O/c1-17-11-14-30(15-12-17)13-4-16-31-23-20-5-2-3-6-21(20)28-22(29-23)18-7-9-19(10-8-18)24(25,26)27/h7-10,17H,2-6,11-16H2,1H3
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 29n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for neuronal nicotinic acetylcholine receptor (nAChR) binding in a whole rat brain preparation using [3H]-cystine as the radioligand.

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157869
PNG
(CHEMBL3785368)
Show SMILES CN1CCN(CCCOc2nc(nc3CCCc23)-c2ccccc2)CC1
Show InChI InChI=1S/C21H28N4O/c1-24-12-14-25(15-13-24)11-6-16-26-21-18-9-5-10-19(18)22-20(23-21)17-7-3-2-4-8-17/h2-4,7-8H,5-6,9-16H2,1H3
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 32n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157868
PNG
(CHEMBL3786998)
Show SMILES CC1CCN(CCCOc2nc(nc3CCCc23)-c2ccccc2)CC1
Show InChI InChI=1S/C22H29N3O/c1-17-11-14-25(15-12-17)13-6-16-26-22-19-9-5-10-20(19)23-21(24-22)18-7-3-2-4-8-18/h2-4,7-8,17H,5-6,9-16H2,1H3
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 32n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for functional activity against neuronal nicotinic acetylcholine receptor(nAChR) expressed in K177 cells using isotopic rubidium efflux assay.

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50034168
PNG
(CHEMBL3359231)
Show SMILES C(COc1nc(nc2CCCc12)-c1ccccc1)CN1CCCCC1
Show InChI InChI=1S/C21H27N3O/c1-3-9-17(10-4-1)20-22-19-12-7-11-18(19)21(23-20)25-16-8-15-24-13-5-2-6-14-24/h1,3-4,9-10H,2,5-8,11-16H2
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 44n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for neuronal nicotinic acetylcholine receptor (nAChR) binding in a whole rat brain preparation using [3H]-cystine as the radioligand.

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50034167
PNG
(CHEMBL3359232)
Show SMILES C(COc1nc(nc2CCCc12)-c1ccccc1)CN1CCCC1
Show InChI InChI=1S/C20H25N3O/c1-2-8-16(9-3-1)19-21-18-11-6-10-17(18)20(22-19)24-15-7-14-23-12-4-5-13-23/h1-3,8-9H,4-7,10-15H2
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 59n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for neuronal nicotinic acetylcholine receptor (nAChR) binding in a whole rat brain preparation using [3H]-cystine as the radioligand.

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157874
PNG
(CHEMBL3786813)
Show SMILES CCN(CC)CCCOc1nc(nc2CCCc12)-c1ccccc1
Show InChI InChI=1S/C20H27N3O/c1-3-23(4-2)14-9-15-24-20-17-12-8-13-18(17)21-19(22-20)16-10-6-5-7-11-16/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3
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 62n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157813
PNG
(CHEMBL3786259)
Show SMILES CCN(CC)CCCOc1nc(nc2CCCCc12)-c1ccccc1
Show InChI InChI=1S/C21H29N3O/c1-3-24(4-2)15-10-16-25-21-18-13-8-9-14-19(18)22-20(23-21)17-11-6-5-7-12-17/h5-7,11-12H,3-4,8-10,13-16H2,1-2H3
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 66n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157871
PNG
(CHEMBL3786461)
Show SMILES C(COc1nc(nc2CCCc12)-c1ccccc1)CN1CCOCC1
Show InChI InChI=1S/C20H25N3O2/c1-2-6-16(7-3-1)19-21-18-9-4-8-17(18)20(22-19)25-13-5-10-23-11-14-24-15-12-23/h1-3,6-7H,4-5,8-15H2
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 103n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for functional activity against neuronal nicotinic acetylcholine receptor(nAChR) expressed in K177 cells using isotopic rubidium efflux assay.

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50034164
PNG
(CHEMBL3352885)
Show SMILES C(COc1nc(nc2CCCCc12)-c1ccccc1)CN1CCCC1
Show InChI InChI=1S/C21H27N3O/c1-2-9-17(10-3-1)20-22-19-12-5-4-11-18(19)21(23-20)25-16-8-15-24-13-6-7-14-24/h1-3,9-10H,4-8,11-16H2
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 112n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157810
PNG
(CHEMBL3787269)
Show SMILES C(COc1nc(nc2CCCCc12)-c1ccccc1)CN1CCOCC1
Show InChI InChI=1S/C21H27N3O2/c1-2-7-17(8-3-1)20-22-19-10-5-4-9-18(19)21(23-20)26-14-6-11-24-12-15-25-16-13-24/h1-3,7-8H,4-6,9-16H2
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 120n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157873
PNG
(CHEMBL3786729)
Show SMILES CN(C)CCCOc1nc(nc2CCCc12)-c1ccccc1
Show InChI InChI=1S/C18H23N3O/c1-21(2)12-7-13-22-18-15-10-6-11-16(15)19-17(20-18)14-8-4-3-5-9-14/h3-5,8-9H,6-7,10-13H2,1-2H3
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 121n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for functional activity against neuronal nicotinic acetylcholine receptor(nAChR) expressed in K177 cells using isotopic rubidium efflux assay.

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157812
PNG
(CHEMBL3787434)
Show SMILES CN(C)CCCOc1nc(nc2CCCCc12)-c1ccccc1
Show InChI InChI=1S/C19H25N3O/c1-22(2)13-8-14-23-19-16-11-6-7-12-17(16)20-18(21-19)15-9-4-3-5-10-15/h3-5,9-10H,6-8,11-14H2,1-2H3
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 138n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50034165
PNG
(CHEMBL3359233)
Show SMILES C(COc1nc(nc2CCCCc12)-c1ccccc1)CN1CCCCC1
Show InChI InChI=1S/C22H29N3O/c1-3-10-18(11-4-1)21-23-20-13-6-5-12-19(20)22(24-21)26-17-9-16-25-14-7-2-8-15-25/h1,3-4,10-11H,2,5-9,12-17H2
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 139n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157811
PNG
(CHEMBL3786949)
Show SMILES O=C1CCN(CCCOc2nc(nc3CCCCc23)-c2ccccc2)CC1
Show InChI InChI=1S/C22H27N3O2/c26-18-11-14-25(15-12-18)13-6-16-27-22-19-9-4-5-10-20(19)23-21(24-22)17-7-2-1-3-8-17/h1-3,7-8H,4-6,9-16H2
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 166n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157872
PNG
(CHEMBL3786283)
Show SMILES O=C1CCN(CCCOc2nc(nc3CCCc23)-c2ccccc2)CC1
Show InChI InChI=1S/C21H25N3O2/c25-17-10-13-24(14-11-17)12-5-15-26-21-18-8-4-9-19(18)22-20(23-21)16-6-2-1-3-7-16/h1-3,6-7H,4-5,8-15H2
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 189n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for functional activity against neuronal nicotinic acetylcholine receptor(nAChR) expressed in K177 cells using isotopic rubidium efflux assay.

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157814
PNG
(CHEMBL3787177)
Show SMILES CC1CCN(CCCCOc2nc(nc3CCCCc23)-c2ccccc2)CC1
Show InChI InChI=1S/C24H33N3O/c1-19-13-16-27(17-14-19)15-7-8-18-28-24-21-11-5-6-12-22(21)25-23(26-24)20-9-3-2-4-10-20/h2-4,9-10,19H,5-8,11-18H2,1H3
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 238n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157815
PNG
(CHEMBL3785416)
Show SMILES CC1CCN(CCCCCOc2nc(nc3CCCCc23)-c2ccccc2)CC1
Show InChI InChI=1S/C25H35N3O/c1-20-14-17-28(18-15-20)16-8-3-9-19-29-25-22-12-6-7-13-23(22)26-24(27-25)21-10-4-2-5-11-21/h2,4-5,10-11,20H,3,6-9,12-19H2,1H3
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 354n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157855
PNG
(CHEMBL3785134)
Show SMILES CC1CCN(CCCCCCOc2nc(nc3CCCCc23)-c2ccccc2)CC1
Show InChI InChI=1S/C26H37N3O/c1-21-15-18-29(19-16-21)17-9-2-3-10-20-30-26-23-13-7-8-14-24(23)27-25(28-26)22-11-5-4-6-12-22/h4-6,11-12,21H,2-3,7-10,13-20H2,1H3
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>2.00E+3n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157877
PNG
(CHEMBL3785243)
Show SMILES C(COc1nc(nc2CCCCc12)-c1ccccc1)CN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C27H32N4O/c1-3-10-22(11-4-1)26-28-25-15-8-7-14-24(25)27(29-26)32-21-9-16-30-17-19-31(20-18-30)23-12-5-2-6-13-23/h1-6,10-13H,7-9,14-21H2
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>2.00E+3n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by liquid scintillation counter

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50157870
PNG
(CHEMBL3786749)
Show SMILES C(COc1nc(nc2CCCc12)-c1ccccc1)CN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C26H30N4O/c1-3-9-21(10-4-1)25-27-24-14-7-13-23(24)26(28-25)31-20-8-15-29-16-18-30(19-17-29)22-11-5-2-6-12-22/h1-6,9-12H,7-8,13-20H2
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>2.00E+3n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for neuronal nicotinic acetylcholine receptor (nAChR) binding in a whole rat brain preparation using [3H]-cystine as the radioligand.

Bioorg Med Chem Lett 26: 2051-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.077
BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%