Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Substance-P receptor (Homo sapiens (Human)) | BDBM50290462 (CHEMBL305119 | potassium 2N-[1-benzyl(methyl)carba...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound for NK-1 receptor was determined in a radioligand binding assay using IM9 human lymphoblastoma cell line. | Bioorg Med Chem Lett 7: 203-208 (1997) Article DOI: 10.1016/S0960-894X(96)00604-X BindingDB Entry DOI: 10.7270/Q2VD6ZGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-K receptor (Rattus norvegicus) | BDBM50290462 (CHEMBL305119 | potassium 2N-[1-benzyl(methyl)carba...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound for NK-3 receptor was determined in vitro using isolated rat portal vein. | Bioorg Med Chem Lett 7: 203-208 (1997) Article DOI: 10.1016/S0960-894X(96)00604-X BindingDB Entry DOI: 10.7270/Q2VD6ZGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-K receptor (Oryctolagus cuniculus) | BDBM50290461 (CHEMBL65468 | potassium 3,5-di(trifluoromethyl)ben...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound for NK-2 receptor was determined in vitro using isolated rabbit pulmonary artery. | Bioorg Med Chem Lett 7: 203-208 (1997) Article DOI: 10.1016/S0960-894X(96)00604-X BindingDB Entry DOI: 10.7270/Q2VD6ZGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-K receptor (Rattus norvegicus) | BDBM50290461 (CHEMBL65468 | potassium 3,5-di(trifluoromethyl)ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound for NK-3 receptor was determined in vitro using isolated rat portal vein. | Bioorg Med Chem Lett 7: 203-208 (1997) Article DOI: 10.1016/S0960-894X(96)00604-X BindingDB Entry DOI: 10.7270/Q2VD6ZGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-K receptor (Oryctolagus cuniculus) | BDBM50290462 (CHEMBL305119 | potassium 2N-[1-benzyl(methyl)carba...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound for NK-2 receptor was determined in vitro using isolated rabbit pulmonary artery. | Bioorg Med Chem Lett 7: 203-208 (1997) Article DOI: 10.1016/S0960-894X(96)00604-X BindingDB Entry DOI: 10.7270/Q2VD6ZGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50290461 (CHEMBL65468 | potassium 3,5-di(trifluoromethyl)ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonistic potency for NK-1 receptor was determined in a radioligand binding assay, using IM9 human lymphoblastoma cell line. | Bioorg Med Chem Lett 7: 203-208 (1997) Article DOI: 10.1016/S0960-894X(96)00604-X BindingDB Entry DOI: 10.7270/Q2VD6ZGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50290461 (CHEMBL65468 | potassium 3,5-di(trifluoromethyl)ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound for NK-1 receptor was determined in vitro using isolated rabbit vena cava. | Bioorg Med Chem Lett 7: 203-208 (1997) Article DOI: 10.1016/S0960-894X(96)00604-X BindingDB Entry DOI: 10.7270/Q2VD6ZGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50290462 (CHEMBL305119 | potassium 2N-[1-benzyl(methyl)carba...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonistic potency for NK-2 receptor was determined in vitro, using isolated rabbit pulmonary artery. | Bioorg Med Chem Lett 7: 203-208 (1997) Article DOI: 10.1016/S0960-894X(96)00604-X BindingDB Entry DOI: 10.7270/Q2VD6ZGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-K receptor (Homo sapiens (Human)) | BDBM50290462 (CHEMBL305119 | potassium 2N-[1-benzyl(methyl)carba...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonistic potency for NK-2 receptor was determined in vitro, using isolated rabbit pulmonary artery. | Bioorg Med Chem Lett 7: 203-208 (1997) Article DOI: 10.1016/S0960-894X(96)00604-X BindingDB Entry DOI: 10.7270/Q2VD6ZGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-K receptor (Homo sapiens (Human)) | BDBM50290461 (CHEMBL65468 | potassium 3,5-di(trifluoromethyl)ben...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound for NK-2 receptor was determined in vitro using isolated rabbit pulmonary artery. | Bioorg Med Chem Lett 7: 203-208 (1997) Article DOI: 10.1016/S0960-894X(96)00604-X BindingDB Entry DOI: 10.7270/Q2VD6ZGN | |||||||||||
More data for this Ligand-Target Pair |