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PubMed code 7473570

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tumor necrosis factor receptor superfamily member 16


(Homo sapiens (Human))		BDBM50029495
PNG
(7-Benzoylamino-4-methyl-9-oxo-4,9-dihydro-pyrazolo...)
Show SMILES Cn1c2cc(nn2c(=O)c2cc(NC(=O)c3ccccc3)ccc12)C(O)=O
Show InChI InChI=1S/C19H14N4O4/c1-22-15-8-7-12(20-17(24)11-5-3-2-4-6-11)9-13(15)18(25)23-16(22)10-14(21-23)19(26)27/h2-10H,1H3,(H,20,24)(H,26,27)
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n/an/a 200n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [125I]- NGF binding to extracellular domain of p75 receptor

J Med Chem 38: 4439-45 (1995)


BindingDB Entry DOI: 10.7270/Q2W37V9R
More data for this
Ligand-Target Pair
Tumor necrosis factor receptor superfamily member 16


(Homo sapiens (Human))		BDBM50029497
PNG
(2-Methyl-7-oxo-5-(tetrazol-1-ylcarbamoyl)-4,7-dihy...)
Show SMILES COC(=O)c1c(C)sc2c(O)cc(nc12)C(=O)Nn1cnnn1
Show InChI InChI=1S/C12H10N6O4S/c1-5-8(12(21)22-2)9-10(23-5)7(19)3-6(14-9)11(20)15-18-4-13-16-17-18/h3-4H,1-2H3,(H,14,19)(H,15,20)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [125I]- NGF binding to extracellular domain of p75 receptor

J Med Chem 38: 4439-45 (1995)


BindingDB Entry DOI: 10.7270/Q2W37V9R
More data for this
Ligand-Target Pair
Tumor necrosis factor receptor superfamily member 16


(Homo sapiens (Human))		BDBM50029494
PNG
(2-Methyl-7-oxo-4,7-dihydro-thieno[3,2-b]pyridine-3...)
Show SMILES COC(=O)c1c(C)sc2c(O)cc(nc12)C(O)=O
Show InChI InChI=1S/C11H9NO5S/c1-4-7(11(16)17-2)8-9(18-4)6(13)3-5(12-8)10(14)15/h3H,1-2H3,(H,12,13)(H,14,15)
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n/an/a 2.30E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [125I]- NGF binding to extracellular domain of p75 receptor

J Med Chem 38: 4439-45 (1995)


BindingDB Entry DOI: 10.7270/Q2W37V9R
More data for this
Ligand-Target Pair
Tumor necrosis factor receptor superfamily member 16


(Homo sapiens (Human))		BDBM50029496
PNG
(6-Amino-4-oxo-1,4-dihydro-quinoline-2-carboxylic a...)
Show SMILES Nc1ccc2nc(cc(O)c2c1)C(O)=O
Show InChI InChI=1S/C10H8N2O3/c11-5-1-2-7-6(3-5)9(13)4-8(12-7)10(14)15/h1-4H,11H2,(H,12,13)(H,14,15)
PDB
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PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [125I]- NGF binding to extracellular domain of p75 receptor

J Med Chem 38: 4439-45 (1995)


BindingDB Entry DOI: 10.7270/Q2W37V9R
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%