BindingDB logo
myBDB logout

PubMed code 8893838

Compile data set for download or QSAR
Found 106 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM82517
PNG
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1
Show InChI InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.600n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054393
PNG
(2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H27F3N4O2/c22-21(23,24)16-5-3-6-17(15-16)26-13-11-25(12-14-26)8-1-2-9-28-19(29)18-7-4-10-27(18)20(28)30/h3,5-6,15,29H,1-2,4,7-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 2.40n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054392
PNG
(2-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H25F3N4O2/c21-20(22,23)15-4-1-5-16(14-15)25-12-10-24(11-13-25)7-3-9-27-18(28)17-6-2-8-26(17)19(27)29/h1,4-5,14,28H,2-3,6-13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 3.80n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054387
PNG
(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Show SMILES COc1ccccc1N1CCN(CCCn2c(O)c3CCCCn3c2=O)CC1
Show InChI InChI=1S/C21H30N4O3/c1-28-19-9-3-2-7-17(19)23-15-13-22(14-16-23)10-6-12-25-20(26)18-8-4-5-11-24(18)21(25)27/h2-3,7,9,26H,4-6,8,10-16H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 4.10n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054359
PNG
(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Show SMILES COc1ccccc1N1CCN(CCCn2c(O)c3CCCn3c2=O)CC1
Show InChI InChI=1S/C20H28N4O3/c1-27-18-8-3-2-6-16(18)22-14-12-21(13-15-22)9-5-11-24-19(25)17-7-4-10-23(17)20(24)26/h2-3,6,8,25H,4-5,7,9-15H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 4.40n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054395
PNG
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCn2c(O)c3CCCn3c2=O)CC1
Show InChI InChI=1S/C21H30N4O3/c1-28-19-9-3-2-7-17(19)23-15-13-22(14-16-23)10-4-5-11-25-20(26)18-8-6-12-24(18)21(25)27/h2-3,7,9,26H,4-6,8,10-16H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 5.5n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054391
PNG
(2-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H27F3N4O2/c22-21(23,24)16-5-3-6-17(15-16)26-13-11-25(12-14-26)8-4-10-28-19(29)18-7-1-2-9-27(18)20(28)30/h3,5-6,15,29H,1-2,4,7-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 5.70n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054354
PNG
(2-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-t...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C21H29ClN4O2/c22-17-6-5-7-18(16-17)24-14-12-23(13-15-24)9-3-4-11-26-20(27)19-8-1-2-10-25(19)21(26)28/h5-7,16,27H,1-4,8-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 7.20n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054362
PNG
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCn2c(O)c3CCCCn3c2=O)CC1
Show InChI InChI=1S/C22H32N4O3/c1-29-20-10-3-2-8-18(20)24-16-14-23(15-17-24)11-6-7-13-26-21(27)19-9-4-5-12-25(19)22(26)28/h2-3,8,10,27H,4-7,9,11-17H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 8.80n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054355
PNG
(2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C22H29F3N4O2/c23-22(24,25)17-6-5-7-18(16-17)27-14-12-26(13-15-27)9-3-4-11-29-20(30)19-8-1-2-10-28(19)21(29)31/h5-7,16,30H,1-4,8-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 9.90n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054351
PNG
(2-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-t...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C20H27ClN4O2/c21-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-1-2-9-25-19(26)18-7-4-10-24(18)20(25)27/h3,5-6,15,26H,1-2,4,7-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 11.3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054374
PNG
(2-[3-(4-Phenyl-piperazin-1-yl)-propyl]-tetrahydro-...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C19H26N4O2/c24-18-17-8-4-10-22(17)19(25)23(18)11-5-9-20-12-14-21(15-13-20)16-6-2-1-3-7-16/h1-3,6-7,24H,4-5,8-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 19.2n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50001859
PNG
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 20.5n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054371
PNG
(2-[4-(4-Phenyl-piperazin-1-yl)-butyl]-tetrahydro-p...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C20H28N4O2/c25-19-18-9-6-12-23(18)20(26)24(19)11-5-4-10-21-13-15-22(16-14-21)17-7-2-1-3-8-17/h1-3,7-8,25H,4-6,9-16H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 24.8n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054398
PNG
(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-tetr...)
Show SMILES COc1ccccc1N1CCN(Cn2c(O)c3CCCCn3c2=O)CC1
Show InChI InChI=1S/C19H26N4O3/c1-26-17-8-3-2-6-15(17)21-12-10-20(11-13-21)14-23-18(24)16-7-4-5-9-22(16)19(23)25/h2-3,6,8,24H,4-5,7,9-14H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 31.7n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054370
PNG
(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-tetr...)
Show SMILES COc1ccccc1N1CCN(Cn2c(O)c3CCCn3c2=O)CC1
Show InChI InChI=1S/C18H24N4O3/c1-25-16-7-3-2-5-14(16)20-11-9-19(10-12-20)13-22-17(23)15-6-4-8-21(15)18(22)24/h2-3,5,7,23H,4,6,8-13H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 34.9n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054361
PNG
(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES COc1ccccc1N1CCN(CCn2c(O)c3CCCCn3c2=O)CC1
Show InChI InChI=1S/C20H28N4O3/c1-27-18-8-3-2-6-16(18)22-13-10-21(11-14-22)12-15-24-19(25)17-7-4-5-9-23(17)20(24)26/h2-3,6,8,25H,4-5,7,9-15H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 45.5n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054368
PNG
(2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C20H27ClN4O2/c21-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)18-7-1-2-9-24(18)20(25)27/h3,5-6,15,26H,1-2,4,7-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 53.6n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054367
PNG
(2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C19H25ClN4O2/c20-15-4-1-5-16(14-15)22-12-10-21(11-13-22)7-3-9-24-18(25)17-6-2-8-23(17)19(24)26/h1,4-5,14,25H,2-3,6-13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 55.9n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054394
PNG
(2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-tetra...)
Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C18H23ClN4O2/c19-14-4-3-5-15(12-14)21-10-8-20(9-11-21)13-23-17(24)16-6-1-2-7-22(16)18(23)25/h3-5,12,24H,1-2,6-11,13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 57.7n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054358
PNG
(2-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-t...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C21H29FN4O2/c22-17-6-8-18(9-7-17)24-15-13-23(14-16-24)10-3-4-12-26-20(27)19-5-1-2-11-25(19)21(26)28/h6-9,27H,1-5,10-16H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 57.9n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054365
PNG
(2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-tetra...)
Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C17H21ClN4O2/c18-13-3-1-4-14(11-13)20-9-7-19(8-10-20)12-22-16(23)15-5-2-6-21(15)17(22)24/h1,3-4,11,23H,2,5-10,12H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 58.4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM82517
PNG
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1
Show InChI InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
 64n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054363
PNG
(2-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H25F3N4O2/c21-20(22,23)15-4-3-5-16(14-15)25-11-8-24(9-12-25)10-13-27-18(28)17-6-1-2-7-26(17)19(27)29/h3-5,14,28H,1-2,6-13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 65.8n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50001862
PNG
((N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl...)
Show SMILES COc1ccccc1N1CCNCC1
Show InChI InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 68n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054366
PNG
(2-[4-(4-Phenyl-piperazin-1-yl)-butyl]-tetrahydro-i...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C21H30N4O2/c26-20-19-10-4-5-12-24(19)21(27)25(20)13-7-6-11-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h1-3,8-9,26H,4-7,10-17H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 78.5n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054353
PNG
(2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C19H23F3N4O2/c20-19(21,22)14-4-3-5-15(12-14)24-10-8-23(9-11-24)13-26-17(27)16-6-1-2-7-25(16)18(26)28/h3-5,12,27H,1-2,6-11,13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 78.6n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054388
PNG
(2-(4-Phenyl-piperazin-1-ylmethyl)-tetrahydro-pyrro...)
Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C17H22N4O2/c22-16-15-7-4-8-20(15)17(23)21(16)13-18-9-11-19(12-10-18)14-5-2-1-3-6-14/h1-3,5-6,22H,4,7-13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 85.3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054378
PNG
(2-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-t...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C20H27FN4O2/c21-16-5-7-17(8-6-16)23-14-12-22(13-15-23)9-1-2-10-25-19(26)18-4-3-11-24(18)20(25)27/h5-8,26H,1-4,9-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 89.9n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054355
PNG
(2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C22H29F3N4O2/c23-22(24,25)17-6-5-7-18(16-17)27-14-12-26(13-15-27)9-3-4-11-29-20(30)19-8-1-2-10-28(19)21(29)31/h5-7,16,30H,1-4,8-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 90.6n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054372
PNG
(2-(4-Phenyl-piperazin-1-ylmethyl)-tetrahydro-imida...)
Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C18H24N4O2/c23-17-16-8-4-5-9-21(16)18(24)22(17)14-19-10-12-20(13-11-19)15-6-2-1-3-7-15/h1-3,6-7,23H,4-5,8-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 101n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054395
PNG
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCn2c(O)c3CCCn3c2=O)CC1
Show InChI InChI=1S/C21H30N4O3/c1-28-19-9-3-2-7-17(19)23-15-13-22(14-16-23)10-4-5-11-25-20(26)18-8-6-12-24(18)21(25)27/h2-3,7,9,26H,4-6,8,10-16H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 107n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054389
PNG
(2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C18H21F3N4O2/c19-18(20,21)13-3-1-4-14(11-13)23-9-7-22(8-10-23)12-25-16(26)15-5-2-6-24(15)17(25)27/h1,3-4,11,26H,2,5-10,12H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 120n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054386
PNG
(2-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C19H23F3N4O2/c20-19(21,22)14-3-1-4-15(13-14)24-10-7-23(8-11-24)9-12-26-17(27)16-5-2-6-25(16)18(26)28/h1,3-4,13,27H,2,5-12H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 123n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054364
PNG
(2-{2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-ethyl}-t...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C19H25ClN4O2/c20-15-4-3-5-16(14-15)22-11-8-21(9-12-22)10-13-24-18(25)17-6-1-2-7-23(17)19(24)26/h3-5,14,25H,1-2,6-13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 128n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054354
PNG
(2-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-t...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C21H29ClN4O2/c22-17-6-5-7-18(16-17)24-14-12-23(13-15-24)9-3-4-11-26-20(27)19-8-1-2-10-25(19)21(26)28/h5-7,16,27H,1-4,8-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 129n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50001915
PNG
(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)
Show SMILES Clc1cccc(c1)N1CCNCC1
Show InChI InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 130n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054351
PNG
(2-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-t...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C20H27ClN4O2/c21-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-1-2-9-25-19(26)18-7-4-10-24(18)20(25)27/h3,5-6,15,26H,1-2,4,7-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 151n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054381
PNG
(2-[3-(4-Phenyl-piperazin-1-yl)-propyl]-tetrahydro-...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C20H28N4O2/c25-19-18-9-4-5-11-23(18)20(26)24(19)12-6-10-21-13-15-22(16-14-21)17-7-2-1-3-8-17/h1-3,7-8,25H,4-6,9-16H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 154n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50007406
PNG
(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)
Show SMILES FC(F)(F)c1cccc(c1)N1CCNCC1
Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 175n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054380
PNG
(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES COc1ccccc1N1CCN(CCn2c(O)c3CCCn3c2=O)CC1
Show InChI InChI=1S/C19H26N4O3/c1-26-17-7-3-2-5-15(17)21-12-9-20(10-13-21)11-14-23-18(24)16-6-4-8-22(16)19(23)25/h2-3,5,7,24H,4,6,8-14H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 234n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054361
PNG
(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES COc1ccccc1N1CCN(CCn2c(O)c3CCCCn3c2=O)CC1
Show InChI InChI=1S/C20H28N4O3/c1-27-18-8-3-2-6-16(18)22-13-10-21(11-14-22)12-15-24-19(25)17-7-4-5-9-23(17)20(24)26/h2-3,6,8,25H,4-5,7,9-15H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 246n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054380
PNG
(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES COc1ccccc1N1CCN(CCn2c(O)c3CCCn3c2=O)CC1
Show InChI InChI=1S/C19H26N4O3/c1-26-17-7-3-2-5-15(17)21-12-9-20(10-13-21)11-14-23-18(24)16-6-4-8-22(16)19(23)25/h2-3,5,7,24H,4,6,8-14H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 361n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50001898
PNG
(1-Phenyl-piperazine | CHEMBL9434 | PHENYLPIPERAZIN...)
Show SMILES C1CN(CCN1)c1ccccc1
Show InChI InChI=1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
 380n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054371
PNG
(2-[4-(4-Phenyl-piperazin-1-yl)-butyl]-tetrahydro-p...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C20H28N4O2/c25-19-18-9-6-12-23(18)20(26)24(19)11-5-4-10-21-13-15-22(16-14-21)17-7-2-1-3-8-17/h1-3,7-8,25H,4-6,9-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 416n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054379
PNG
(2-{2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-ethyl}-t...)
Show SMILES Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C18H23ClN4O2/c19-14-3-1-4-15(13-14)21-10-7-20(8-11-21)9-12-23-17(24)16-5-2-6-22(16)18(23)25/h1,3-4,13,24H,2,5-12H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 418n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054390
PNG
(2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-tetra...)
Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C18H23FN4O2/c19-14-4-6-15(7-5-14)21-11-9-20(10-12-21)13-23-17(24)16-3-1-2-8-22(16)18(23)25/h4-7,24H,1-3,8-13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 444n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50001859
PNG
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 482n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Compound was evaluated for the binding affinity towards 5-hydroxytryptamine 2A receptor using [3H]-ketanserin radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054377
PNG
(2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-tetra...)
Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C17H21FN4O2/c18-13-3-5-14(6-4-13)20-10-8-19(9-11-20)12-22-16(23)15-2-1-7-21(15)17(22)24/h3-6,23H,1-2,7-12H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 500n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054383
PNG
(2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C20H27FN4O2/c21-16-5-7-17(8-6-16)23-14-12-22(13-15-23)9-3-11-25-19(26)18-4-1-2-10-24(18)20(25)27/h5-8,26H,1-4,9-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 598n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054358
PNG
(2-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-t...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C21H29FN4O2/c22-17-6-8-18(9-7-17)24-15-13-23(14-16-24)10-3-4-12-26-20(27)19-5-1-2-11-25(19)21(26)28/h6-9,27H,1-5,10-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 615n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50001859
PNG
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 852n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054367
PNG
(2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C19H25ClN4O2/c20-15-4-1-5-16(14-15)22-12-10-21(11-13-22)7-3-9-24-18(25)17-6-2-8-23(17)19(24)26/h1,4-5,14,25H,2-3,6-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054382
PNG
(2-{4-[4-(4-Nitro-phenyl)-piperazin-1-yl]-butyl}-te...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C20H27N5O4/c26-19-18-4-3-11-23(18)20(27)24(19)10-2-1-9-21-12-14-22(15-13-21)16-5-7-17(8-6-16)25(28)29/h5-8,26H,1-4,9-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054397
PNG
(2-[4-(4-Nitro-phenyl)-piperazin-1-ylmethyl]-tetrah...)
Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C18H23N5O4/c24-17-16-3-1-2-8-21(16)18(25)22(17)13-19-9-11-20(12-10-19)14-4-6-15(7-5-14)23(26)27/h4-7,24H,1-3,8-13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50054398
PNG
(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-tetr...)
Show SMILES COc1ccccc1N1CCN(Cn2c(O)c3CCCCn3c2=O)CC1
Show InChI InChI=1S/C19H26N4O3/c1-26-17-8-3-2-6-15(17)21-12-10-20(11-13-21)14-23-18(24)16-7-4-5-9-22(16)19(23)25/h2-3,6,8,24H,4-5,7,9-14H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Compound was evaluated for the binding affinity towards 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054381
PNG
(2-[3-(4-Phenyl-piperazin-1-yl)-propyl]-tetrahydro-...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C20H28N4O2/c25-19-18-9-4-5-11-23(18)20(26)24(19)12-6-10-21-13-15-22(16-14-21)17-7-2-1-3-8-17/h1-3,7-8,25H,4-6,9-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054357
PNG
(2-{4-[4-(4-Nitro-phenyl)-piperazin-1-yl]-butyl}-te...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C21H29N5O4/c27-20-19-5-1-2-11-24(19)21(28)25(20)12-4-3-10-22-13-15-23(16-14-22)17-6-8-18(9-7-17)26(29)30/h6-9,27H,1-5,10-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054363
PNG
(2-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H25F3N4O2/c21-20(22,23)15-4-3-5-16(14-15)25-11-8-24(9-12-25)10-13-27-18(28)17-6-1-2-7-26(17)19(27)29/h3-5,14,28H,1-2,6-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054369
PNG
(2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C19H25FN4O2/c20-15-4-6-16(7-5-15)22-13-11-21(12-14-22)8-2-10-24-18(25)17-3-1-9-23(17)19(24)26/h4-7,25H,1-3,8-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054376
PNG
(2-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-tetrahydro-p...)
Show SMILES Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C18H24N4O2/c23-17-16-7-4-8-21(16)18(24)22(17)14-11-19-9-12-20(13-10-19)15-5-2-1-3-6-15/h1-3,5-6,23H,4,7-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054376
PNG
(2-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-tetrahydro-p...)
Show SMILES Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C18H24N4O2/c23-17-16-7-4-8-21(16)18(24)22(17)14-11-19-9-12-20(13-10-19)15-5-2-1-3-6-15/h1-3,5-6,23H,4,7-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054353
PNG
(2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C19H23F3N4O2/c20-19(21,22)14-4-3-5-15(12-14)24-10-8-23(9-11-24)13-26-17(27)16-6-1-2-7-25(16)18(26)28/h3-5,12,27H,1-2,6-11,13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054369
PNG
(2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C19H25FN4O2/c20-15-4-6-16(7-5-15)22-13-11-21(12-14-22)8-2-10-24-18(25)17-3-1-9-23(17)19(24)26/h4-7,25H,1-3,8-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054362
PNG
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCn2c(O)c3CCCCn3c2=O)CC1
Show InChI InChI=1S/C22H32N4O3/c1-29-20-10-3-2-8-18(20)24-16-14-23(15-17-24)11-6-7-13-26-21(27)19-9-4-5-12-25(19)22(26)28/h2-3,8,10,27H,4-7,9,11-17H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054374
PNG
(2-[3-(4-Phenyl-piperazin-1-yl)-propyl]-tetrahydro-...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C19H26N4O2/c24-18-17-8-4-10-22(17)19(25)23(18)11-5-9-20-12-14-21(15-13-20)16-6-2-1-3-7-16/h1-3,6-7,24H,4-5,8-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054357
PNG
(2-{4-[4-(4-Nitro-phenyl)-piperazin-1-yl]-butyl}-te...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C21H29N5O4/c27-20-19-5-1-2-11-24(19)21(28)25(20)12-4-3-10-22-13-15-23(16-14-22)17-6-8-18(9-7-17)26(29)30/h6-9,27H,1-5,10-16H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054389
PNG
(2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C18H21F3N4O2/c19-18(20,21)13-3-1-4-14(11-13)23-9-7-22(8-10-23)12-25-16(26)15-5-2-6-24(15)17(25)27/h1,3-4,11,26H,2,5-10,12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054378
PNG
(2-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-t...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C20H27FN4O2/c21-16-5-7-17(8-6-16)23-14-12-22(13-15-23)9-1-2-10-25-19(26)18-4-3-11-24(18)20(25)27/h5-8,26H,1-4,9-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054352
PNG
(2-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-tetrahydro-i...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C19H26N4O2/c24-18-17-8-4-5-9-22(17)19(25)23(18)15-12-20-10-13-21(14-11-20)16-6-2-1-3-7-16/h1-3,6-7,24H,4-5,8-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054366
PNG
(2-[4-(4-Phenyl-piperazin-1-yl)-butyl]-tetrahydro-i...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C21H30N4O2/c26-20-19-10-4-5-12-24(19)21(27)25(20)13-7-6-11-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h1-3,8-9,26H,4-7,10-17H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054360
PNG
(2-[4-(4-Nitro-phenyl)-piperazin-1-ylmethyl]-tetrah...)
Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C17H21N5O4/c23-16-15-2-1-7-20(15)17(24)21(16)12-18-8-10-19(11-9-18)13-3-5-14(6-4-13)22(25)26/h3-6,23H,1-2,7-12H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054359
PNG
(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Show SMILES COc1ccccc1N1CCN(CCCn2c(O)c3CCCn3c2=O)CC1
Show InChI InChI=1S/C20H28N4O3/c1-27-18-8-3-2-6-16(18)22-14-12-21(13-15-22)9-5-11-24-19(25)17-7-4-10-23(17)20(24)26/h2-3,6,8,25H,4-5,7,9-15H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054392
PNG
(2-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H25F3N4O2/c21-20(22,23)15-4-1-5-16(14-15)25-12-10-24(11-13-25)7-3-9-27-18(28)17-6-2-8-26(17)19(27)29/h1,4-5,14,28H,2-3,6-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054387
PNG
(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Show SMILES COc1ccccc1N1CCN(CCCn2c(O)c3CCCCn3c2=O)CC1
Show InChI InChI=1S/C21H30N4O3/c1-28-19-9-3-2-7-17(19)23-15-13-22(14-16-23)10-6-12-25-20(26)18-8-4-5-11-24(18)21(25)27/h2-3,7,9,26H,4-6,8,10-16H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054382
PNG
(2-{4-[4-(4-Nitro-phenyl)-piperazin-1-yl]-butyl}-te...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C20H27N5O4/c26-19-18-4-3-11-23(18)20(27)24(19)10-2-1-9-21-12-14-22(15-13-21)16-5-7-17(8-6-16)25(28)29/h5-8,26H,1-4,9-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054386
PNG
(2-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C19H23F3N4O2/c20-19(21,22)14-3-1-4-15(13-14)24-10-7-23(8-11-24)9-12-26-17(27)16-5-2-6-25(16)18(26)28/h1,3-4,13,27H,2,5-12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054393
PNG
(2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H27F3N4O2/c22-21(23,24)16-5-3-6-17(15-16)26-13-11-25(12-14-26)8-1-2-9-28-19(29)18-7-4-10-27(18)20(28)30/h3,5-6,15,29H,1-2,4,7-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054370
PNG
(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-tetr...)
Show SMILES COc1ccccc1N1CCN(Cn2c(O)c3CCCn3c2=O)CC1
Show InChI InChI=1S/C18H24N4O3/c1-25-16-7-3-2-5-14(16)20-11-9-19(10-12-20)13-22-17(23)15-6-4-8-21(15)18(22)24/h2-3,5,7,23H,4,6,8-13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054391
PNG
(2-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H27F3N4O2/c22-21(23,24)16-5-3-6-17(15-16)26-13-11-25(12-14-26)8-4-10-28-19(29)18-7-1-2-9-27(18)20(28)30/h3,5-6,15,29H,1-2,4,7-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054364
PNG
(2-{2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-ethyl}-t...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C19H25ClN4O2/c20-15-4-3-5-16(14-15)22-11-8-21(9-12-22)10-13-24-18(25)17-6-1-2-7-23(17)19(24)26/h3-5,14,25H,1-2,6-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054368
PNG
(2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C20H27ClN4O2/c21-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)18-7-1-2-9-24(18)20(25)27/h3,5-6,15,26H,1-2,4,7-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054352
PNG
(2-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-tetrahydro-i...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C19H26N4O2/c24-18-17-8-4-5-9-22(17)19(25)23(18)15-12-20-10-13-21(14-11-20)16-6-2-1-3-7-16/h1-3,6-7,24H,4-5,8-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054383
PNG
(2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C20H27FN4O2/c21-16-5-7-17(8-6-16)23-14-12-22(13-15-23)9-3-11-25-19(26)18-4-1-2-10-24(18)20(25)27/h5-8,26H,1-4,9-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054379
PNG
(2-{2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-ethyl}-t...)
Show SMILES Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C18H23ClN4O2/c19-14-3-1-4-15(13-14)21-10-7-20(8-11-21)9-12-23-17(24)16-5-2-6-22(16)18(23)25/h1,3-4,13,24H,2,5-12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054365
PNG
(2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-tetra...)
Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C17H21ClN4O2/c18-13-3-1-4-14(11-13)20-9-7-19(8-10-20)12-22-16(23)15-5-2-6-21(15)17(22)24/h1,3-4,11,23H,2,5-10,12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054384
PNG
(2-{3-[4-(4-Nitro-phenyl)-piperazin-1-yl]-propyl}-t...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C20H27N5O4/c26-19-18-4-1-2-10-23(18)20(27)24(19)11-3-9-21-12-14-22(15-13-21)16-5-7-17(8-6-16)25(28)29/h5-8,26H,1-4,9-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054388
PNG
(2-(4-Phenyl-piperazin-1-ylmethyl)-tetrahydro-pyrro...)
Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C17H22N4O2/c22-16-15-7-4-8-20(15)17(23)21(16)13-18-9-11-19(12-10-18)14-5-2-1-3-6-14/h1-3,5-6,22H,4,7-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054356
PNG
(2-{3-[4-(4-Nitro-phenyl)-piperazin-1-yl]-propyl}-t...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C19H25N5O4/c25-18-17-3-1-9-22(17)19(26)23(18)10-2-8-20-11-13-21(14-12-20)15-4-6-16(7-5-15)24(27)28/h4-7,25H,1-3,8-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054396
PNG
(2-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-t...)
Show SMILES Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C18H23FN4O2/c19-14-3-5-15(6-4-14)21-11-8-20(9-12-21)10-13-23-17(24)16-2-1-7-22(16)18(23)25/h3-6,24H,1-2,7-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054385
PNG
(2-{2-[4-(4-Nitro-phenyl)-piperazin-1-yl]-ethyl}-te...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C19H25N5O4/c25-18-17-3-1-2-8-22(17)19(26)23(18)14-11-20-9-12-21(13-10-20)15-4-6-16(7-5-15)24(27)28/h4-7,25H,1-3,8-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054373
PNG
(2-{2-[4-(4-Nitro-phenyl)-piperazin-1-yl]-ethyl}-te...)
Show SMILES Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C18H23N5O4/c24-17-16-2-1-7-21(16)18(25)22(17)13-10-19-8-11-20(12-9-19)14-3-5-15(6-4-14)23(26)27/h3-6,24H,1-2,7-13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054377
PNG
(2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-tetra...)
Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C17H21FN4O2/c18-13-3-5-14(6-4-13)20-10-8-19(9-11-20)12-22-16(23)15-2-1-7-21(15)17(22)24/h3-6,23H,1-2,7-12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054373
PNG
(2-{2-[4-(4-Nitro-phenyl)-piperazin-1-yl]-ethyl}-te...)
Show SMILES Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C18H23N5O4/c24-17-16-2-1-7-21(16)18(25)22(17)13-10-19-8-11-20(12-9-19)14-3-5-15(6-4-14)23(26)27/h3-6,24H,1-2,7-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054384
PNG
(2-{3-[4-(4-Nitro-phenyl)-piperazin-1-yl]-propyl}-t...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C20H27N5O4/c26-19-18-4-1-2-10-23(18)20(27)24(19)11-3-9-21-12-14-22(15-13-21)16-5-7-17(8-6-16)25(28)29/h5-8,26H,1-4,9-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054394
PNG
(2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-tetra...)
Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C18H23ClN4O2/c19-14-4-3-5-15(12-14)21-10-8-20(9-11-21)13-23-17(24)16-6-1-2-7-22(16)18(23)25/h3-5,12,24H,1-2,6-11,13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054360
PNG
(2-[4-(4-Nitro-phenyl)-piperazin-1-ylmethyl]-tetrah...)
Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C17H21N5O4/c23-16-15-2-1-7-20(15)17(24)21(16)12-18-8-10-19(11-9-18)13-3-5-14(6-4-13)22(25)26/h3-6,23H,1-2,7-12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054398
PNG
(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-tetr...)
Show SMILES COc1ccccc1N1CCN(Cn2c(O)c3CCCCn3c2=O)CC1
Show InChI InChI=1S/C19H26N4O3/c1-26-17-8-3-2-6-15(17)21-12-10-20(11-13-21)14-23-18(24)16-7-4-5-9-22(16)19(23)25/h2-3,6,8,24H,4-5,7,9-14H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054372
PNG
(2-(4-Phenyl-piperazin-1-ylmethyl)-tetrahydro-imida...)
Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C18H24N4O2/c23-17-16-8-4-5-9-21(16)18(24)22(17)14-19-10-12-20(13-11-19)15-6-2-1-3-7-15/h1-3,6-7,23H,4-5,8-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054375
PNG
(2-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-t...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C19H25FN4O2/c20-15-4-6-16(7-5-15)22-12-9-21(10-13-22)11-14-24-18(25)17-3-1-2-8-23(17)19(24)26/h4-7,25H,1-3,8-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054397
PNG
(2-[4-(4-Nitro-phenyl)-piperazin-1-ylmethyl]-tetrah...)
Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C18H23N5O4/c24-17-16-3-1-2-8-21(16)18(25)22(17)13-19-9-11-20(12-10-19)14-4-6-15(7-5-14)23(26)27/h4-7,24H,1-3,8-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054385
PNG
(2-{2-[4-(4-Nitro-phenyl)-piperazin-1-yl]-ethyl}-te...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C19H25N5O4/c25-18-17-3-1-2-8-22(17)19(26)23(18)14-11-20-9-12-21(13-10-20)15-4-6-16(7-5-15)24(27)28/h4-7,25H,1-3,8-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054356
PNG
(2-{3-[4-(4-Nitro-phenyl)-piperazin-1-yl]-propyl}-t...)
Show SMILES Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C19H25N5O4/c25-18-17-3-1-9-22(17)19(26)23(18)10-2-8-20-11-13-21(14-12-20)15-4-6-16(7-5-15)24(27)28/h4-7,25H,1-3,8-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054375
PNG
(2-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-t...)
Show SMILES Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C19H25FN4O2/c20-15-4-6-16(7-5-15)22-12-9-21(10-13-22)11-14-24-18(25)17-3-1-2-8-23(17)19(24)26/h4-7,25H,1-3,8-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50054390
PNG
(2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-tetra...)
Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C18H23FN4O2/c19-14-4-6-15(7-5-14)21-11-9-20(10-12-21)13-23-17(24)16-3-1-2-8-22(16)18(23)25/h4-7,24H,1-3,8-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50054396
PNG
(2-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-t...)
Show SMILES Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C18H23FN4O2/c19-14-3-5-15(6-4-14)21-11-8-20(9-12-21)10-13-23-17(24)16-2-1-7-22(16)18(23)25/h3-6,24H,1-2,7-13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.

J Med Chem 39: 4439-50 (1996)


Article DOI: 10.1021/jm960416g
BindingDB Entry DOI: 10.7270/Q2WS8SBN
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%