BindingDB logo
myBDB logout

PubMed code 9057862

Compile data set for download or QSAR
Found 41 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50038168
PNG
(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)
Show SMILES Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C21H14ClNO3/c22-14-9-10-17-18(12-14)23-21(25)19(20(17)24)13-5-4-8-16(11-13)26-15-6-2-1-3-7-15/h1-12H,(H2,23,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056659
PNG
(CHEMBL165371 | [7-Chloro-2-oxo-3-(3-phenoxy-phenyl...)
Show SMILES OC(=O)COc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C23H16ClNO5/c24-15-9-10-18-19(12-15)25-23(28)21(22(18)29-13-20(26)27)14-5-4-8-17(11-14)30-16-6-2-1-3-7-16/h1-12H,13H2,(H,25,28)(H,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056667
PNG
((7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-yl...)
Show SMILES OC(=O)COc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C17H12ClNO4/c18-11-6-7-12-13(8-11)19-17(22)15(10-4-2-1-3-5-10)16(12)23-9-14(20)21/h1-8H,9H2,(H,19,22)(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056663
PNG
((7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-yl...)
Show SMILES OC(=O)Cc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C17H12ClNO3/c18-11-6-7-12-13(9-15(20)21)16(10-4-2-1-3-5-10)17(22)19-14(12)8-11/h1-8H,9H2,(H,19,22)(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 160n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50041467
PNG
(7-Chloro-4-hydroxy-3-phenyl-1H-quinolin-2-one | 7-...)
Show SMILES Oc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C15H10ClNO2/c16-10-6-7-11-12(8-10)17-15(19)13(14(11)18)9-4-2-1-3-5-9/h1-8H,(H2,17,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 170n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056673
PNG
(3-(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-...)
Show SMILES OC(=O)CCc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C18H14ClNO3/c19-12-6-7-13-14(8-9-16(21)22)17(11-4-2-1-3-5-11)18(23)20-15(13)10-12/h1-7,10H,8-9H2,(H,20,23)(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 170n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056657
PNG
(3-(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-...)
Show SMILES NC(=O)CCc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C18H15ClN2O2/c19-12-6-7-13-14(8-9-16(20)22)17(11-4-2-1-3-5-11)18(23)21-15(13)10-12/h1-7,10H,8-9H2,(H2,20,22)(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056653
PNG
(7-Chloro-3-phenyl-4-[2-(1H-tetrazol-5-yl)-ethyl]-1...)
Show SMILES Clc1ccc2c(CCc3nn[nH]n3)c(-c3ccccc3)c(=O)[nH]c2c1
Show InChI InChI=1S/C18H14ClN5O/c19-12-6-7-13-14(8-9-16-21-23-24-22-16)17(11-4-2-1-3-5-11)18(25)20-15(13)10-12/h1-7,10H,8-9H2,(H,20,25)(H,21,22,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056652
PNG
(CHEMBL351884 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Show SMILES CS(=O)(=O)Nc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C16H13ClN2O3S/c1-23(21,22)19-15-12-8-7-11(17)9-13(12)18-16(20)14(15)10-5-3-2-4-6-10/h2-9H,1H3,(H2,18,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 270n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056645
PNG
((7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-yl...)
Show SMILES Clc1ccc2c(OCC#N)c(-c3ccccc3)c(=O)[nH]c2c1
Show InChI InChI=1S/C17H11ClN2O2/c18-12-6-7-13-14(10-12)20-17(21)15(16(13)22-9-8-19)11-4-2-1-3-5-11/h1-7,10H,9H2,(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 320n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056672
PNG
(4-Amino-7-chloro-3-(3-phenoxy-phenyl)-1H-quinolin-...)
Show SMILES Nc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C21H15ClN2O2/c22-14-9-10-17-18(12-14)24-21(25)19(20(17)23)13-5-4-8-16(11-13)26-15-6-2-1-3-7-15/h1-12H,(H3,23,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056654
PNG
(2-(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-...)
Show SMILES NC(=O)COc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C17H13ClN2O3/c18-11-6-7-12-13(8-11)20-17(22)15(10-4-2-1-3-5-10)16(12)23-9-14(19)21/h1-8H,9H2,(H2,19,21)(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056661
PNG
(3-(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-...)
Show SMILES COC(=O)CCc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C19H16ClNO3/c1-24-17(22)10-9-15-14-8-7-13(20)11-16(14)21-19(23)18(15)12-5-3-2-4-6-12/h2-8,11H,9-10H2,1H3,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056656
PNG
(CHEMBL166246 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Show SMILES OC(=O)C(=O)Nc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C17H11ClN2O4/c18-10-6-7-11-12(8-10)19-15(21)13(9-4-2-1-3-5-9)14(11)20-16(22)17(23)24/h1-8H,(H,23,24)(H2,19,20,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 580n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056671
PNG
(3-(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-...)
Show SMILES Clc1ccc2c(CCC#N)c(-c3ccccc3)c(=O)[nH]c2c1
Show InChI InChI=1S/C18H13ClN2O/c19-13-8-9-14-15(7-4-10-20)17(12-5-2-1-3-6-12)18(22)21-16(14)11-13/h1-3,5-6,8-9,11H,4,7H2,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 750n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056647
PNG
(7-Chloro-4-{2-[(E)-hydroxyimino]-propoxy}-3-phenyl...)
Show SMILES CC(COc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12)N=O
Show InChI InChI=1S/C18H15ClN2O3/c1-11(21-23)10-24-17-14-8-7-13(19)9-15(14)20-18(22)16(17)12-5-3-2-4-6-12/h2-9,11H,10H2,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 780n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056639
PNG
(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinoline-4-ca...)
Show SMILES OC(=O)c1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C16H10ClNO3/c17-10-6-7-11-12(8-10)18-15(19)13(14(11)16(20)21)9-4-2-1-3-5-9/h1-8H,(H,18,19)(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 900n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056644
PNG
(CHEMBL164831 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Show SMILES OC(=O)CC(=O)Nc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C18H13ClN2O4/c19-11-6-7-12-13(8-11)20-18(25)16(10-4-2-1-3-5-10)17(12)21-14(22)9-15(23)24/h1-8H,9H2,(H,23,24)(H2,20,21,22,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056637
PNG
((7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-yl...)
Show SMILES COC(=O)Cc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C18H14ClNO3/c1-23-16(21)10-14-13-8-7-12(19)9-15(13)20-18(22)17(14)11-5-3-2-4-6-11/h2-9H,10H2,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056665
PNG
(CHEMBL433908 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Show SMILES Clc1ccc2c(NS(=O)(=O)c3ccccc3)c(-c3ccccc3)c(=O)[nH]c2c1
Show InChI InChI=1S/C21H15ClN2O3S/c22-15-11-12-17-18(13-15)23-21(25)19(14-7-3-1-4-8-14)20(17)24-28(26,27)16-9-5-2-6-10-16/h1-13H,(H2,23,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.19E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056648
PNG
(CHEMBL164184 | [7-Chloro-2-oxo-3-(3-phenoxy-phenyl...)
Show SMILES Clc1ccc2c(OCC#N)c(-c3cccc(Oc4ccccc4)c3)c(=O)[nH]c2c1
Show InChI InChI=1S/C23H15ClN2O3/c24-16-9-10-19-20(14-16)26-23(27)21(22(19)28-12-11-25)15-5-4-8-18(13-15)29-17-6-2-1-3-7-17/h1-10,13-14H,12H2,(H,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056643
PNG
(7-Chloro-4-(2-oxo-propoxy)-3-phenyl-1H-quinolin-2-...)
Show SMILES CC(=O)COc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C18H14ClNO3/c1-11(21)10-23-17-14-8-7-13(19)9-15(14)20-18(22)16(17)12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056641
PNG
(4-Benzylamino-7-chloro-3-phenyl-1H-quinolin-2-one ...)
Show SMILES Clc1ccc2c(NCc3ccccc3)c(-c3ccccc3)c(=O)[nH]c2c1
Show InChI InChI=1S/C22H17ClN2O/c23-17-11-12-18-19(13-17)25-22(26)20(16-9-5-2-6-10-16)21(18)24-14-15-7-3-1-4-8-15/h1-13H,14H2,(H2,24,25,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056666
PNG
(CHEMBL352889 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Show SMILES COC(=O)C(=O)Nc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C18H13ClN2O4/c1-25-18(24)17(23)21-15-12-8-7-11(19)9-13(12)20-16(22)14(15)10-5-3-2-4-6-10/h2-9H,1H3,(H2,20,21,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056638
PNG
(7-Chloro-3-phenyl-4-(pyridin-2-ylmethoxy)-1H-quino...)
Show SMILES Clc1ccc2c(OCc3ccccn3)c(-c3ccccc3)c(=O)[nH]c2c1
Show InChI InChI=1S/C21H15ClN2O2/c22-15-9-10-17-18(12-15)24-21(25)19(14-6-2-1-3-7-14)20(17)26-13-16-8-4-5-11-23-16/h1-12H,13H2,(H,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056649
PNG
(7-Chloro-4-(2-dimethylamino-ethylamino)-3-phenyl-1...)
Show SMILES CN(C)CCNc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C19H20ClN3O/c1-23(2)11-10-21-18-15-9-8-14(20)12-16(15)22-19(24)17(18)13-6-4-3-5-7-13/h3-9,12H,10-11H2,1-2H3,(H2,21,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 3.20E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056642
PNG
((7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-yl...)
Show SMILES COC(=O)COc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C18H14ClNO4/c1-23-15(21)10-24-17-13-8-7-12(19)9-14(13)20-18(22)16(17)11-5-3-2-4-6-11/h2-9H,10H2,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 3.20E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056651
PNG
(7-Chloro-4-[2-(3-methyl-[1,2,4]oxadiazol-5-yl)-eth...)
Show SMILES Cc1noc(CCc2c(-c3ccccc3)c(=O)[nH]c3cc(Cl)ccc23)n1
Show InChI InChI=1S/C20H16ClN3O2/c1-12-22-18(26-24-12)10-9-16-15-8-7-14(21)11-17(15)23-20(25)19(16)13-5-3-2-4-6-13/h2-8,11H,9-10H2,1H3,(H,23,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056662
PNG
(7-Chloro-4-(3-dimethylamino-propylamino)-3-phenyl-...)
Show SMILES CN(C)CCCNc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C20H22ClN3O/c1-24(2)12-6-11-22-19-16-10-9-15(21)13-17(16)23-20(25)18(19)14-7-4-3-5-8-14/h3-5,7-10,13H,6,11-12H2,1-2H3,(H2,22,23,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 4.20E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056669
PNG
(4-Amino-7-chloro-3-phenyl-1H-quinolin-2-one | CHEM...)
Show SMILES Nc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C15H11ClN2O/c16-10-6-7-11-12(8-10)18-15(19)13(14(11)17)9-4-2-1-3-5-9/h1-8H,(H3,17,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 6.70E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056660
PNG
(7-Chloro-4-(2-dimethylamino-ethoxy)-3-phenyl-1H-qu...)
Show SMILES CN(C)CCOc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C19H19ClN2O2/c1-22(2)10-11-24-18-15-9-8-14(20)12-16(15)21-19(23)17(18)13-6-4-3-5-7-13/h3-9,12H,10-11H2,1-2H3,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056650
PNG
(2-(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-...)
Show SMILES CN(C)C(=O)COc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C19H17ClN2O3/c1-22(2)16(23)11-25-18-14-9-8-13(20)10-15(14)21-19(24)17(18)12-6-4-3-5-7-12/h3-10H,11H2,1-2H3,(H,21,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.16E+4n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056655
PNG
(CHEMBL164295 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Show SMILES CC(=O)Nc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C17H13ClN2O2/c1-10(21)19-16-13-8-7-12(18)9-14(13)20-17(22)15(16)11-5-3-2-4-6-11/h2-9H,1H3,(H2,19,20,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.47E+4n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056670
PNG
(CHEMBL164085 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Show SMILES CN(C)CCNC(=O)C(=O)Nc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C21H21ClN4O3/c1-26(2)11-10-23-20(28)21(29)25-18-15-9-8-14(22)12-16(15)24-19(27)17(18)13-6-4-3-5-7-13/h3-9,12H,10-11H2,1-2H3,(H,23,28)(H2,24,25,27,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056640
PNG
(7-Chloro-4-dimethylamino-3-phenyl-1H-quinolin-2-on...)
Show SMILES CN(C)c1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C17H15ClN2O/c1-20(2)16-13-9-8-12(18)10-14(13)19-17(21)15(16)11-6-4-3-5-7-11/h3-10H,1-2H3,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056635
PNG
(7-Chloro-4-ethyl-3-phenyl-1H-quinolin-2-one | CHEM...)
Show SMILES CCc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C17H14ClNO/c1-2-13-14-9-8-12(18)10-15(14)19-17(20)16(13)11-6-4-3-5-7-11/h3-10H,2H2,1H3,(H,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056636
PNG
(7-Chloro-4-methylamino-3-phenyl-1H-quinolin-2-one ...)
Show SMILES CNc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C16H13ClN2O/c1-18-15-12-8-7-11(17)9-13(12)19-16(20)14(15)10-5-3-2-4-6-10/h2-9H,1H3,(H2,18,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056658
PNG
(7-Chloro-4-methoxy-3-phenyl-1H-quinolin-2-one | CH...)
Show SMILES COc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C16H12ClNO2/c1-20-15-12-8-7-11(17)9-13(12)18-16(19)14(15)10-5-3-2-4-6-10/h2-9H,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056664
PNG
(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinoline-4-ca...)
Show SMILES Clc1ccc2c(C(=O)NCc3ccccc3)c(-c3ccccc3)c(=O)[nH]c2c1
Show InChI InChI=1S/C23H17ClN2O2/c24-17-11-12-18-19(13-17)26-23(28)20(16-9-5-2-6-10-16)21(18)22(27)25-14-15-7-3-1-4-8-15/h1-13H,14H2,(H,25,27)(H,26,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056668
PNG
(CHEMBL350411 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Show SMILES Clc1ccc2c(NC(=O)Cc3ccccc3)c(-c3ccccc3)c(=O)[nH]c2c1
Show InChI InChI=1S/C23H17ClN2O2/c24-17-11-12-18-19(14-17)25-23(28)21(16-9-5-2-6-10-16)22(18)26-20(27)13-15-7-3-1-4-8-15/h1-12,14H,13H2,(H2,25,26,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056646
PNG
(7-Chloro-3-phenyl-1H-quinolin-2-one | CHEMBL423646)
Show SMILES Clc1ccc2cc(-c3ccccc3)c(=O)[nH]c2c1
Show InChI InChI=1S/C15H10ClNO/c16-12-7-6-11-8-13(10-4-2-1-3-5-10)15(18)17-14(11)9-12/h1-9H,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%