Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373109 (1-(2-methyl-4- phenyl-1,3-thiazol- 5-yl)-3-(2- phe...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373084 (1,3-bis(2- phenylimidazo[1,2- a]pyridin-3-yl)urea ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373104 (1-(2-methyl-4- phenylpyrimidin-5- yl)-3-(2- phenyl...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373085 (1-(1,3-diphenyl-1H- pyrazol-5-yl)-3- pyridin-2-ylu...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373101 (1,3-bis[2- (methylsulfanyl)-4- phenylpyrimidin-5- ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373099 (1-naphthalen-1-yl-3- (6- phenylimidazo[2,1- b][1,3...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373097 (1-(5-methyl-3- phenylisoxazol-4- yl)-3-[2- (triflu...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373092 (1-(1-phenyl-3- pyridin-4-yl-1H- pyrazol-5-yl)-3- p...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373130 (1-(5-methyl-3- phenylisoxazol-4- yl)-3-{2- [(trifl...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373129 (1-(1-phenyl-1H- pyrazol-5-yl)-3-{2- [(trifluoromet...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373089 (1-biphenyl-2-yl-3- (3-methyl-1-phenyl- 1H-pyrazol-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373107 (1-(2- phenylimidazo[1,2- a]pyridin-3-yl)-3-(2- phe...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373111 (US9896447, Compound 28 | ethyl 3-{[(2- phenylimida...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373108 (1-(3-methyl-1- phenyl-1H-pyrazol- 5-yl)-3-(2- phen...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373102 (1-(2-methyl-4- phenylpyrimidin-5- yl)-3-(2-phenyl-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373087 (1-(3-methyl-1- phenyl-1H-pyrazol- 5-yl)-3-naphthal...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373118 (1,3-bis(2-methyl-4- phenyl-1,3-thiazol- 5-yl)urea ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373124 (1-(2-methyl-4- phenylpyrimidin-5- yl)-3-{2- [(trif...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373114 (1-(6-chloro-2- phenylimidazo[1,2- b]pyridazin-3-yl...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373115 (N-methyl-3-{[(2- phenylimidazo[1,2- a]pyridin-3- y...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373095 (1-(6-methyl-2- phenylpyridin-3-yl)- 3-pyridin-2-yl...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373121 (1-[5-fluoro-2- (trifluoromethyl) benzyl]-3-(1-phen...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373112 (1-(2- phenylimidazo[1,2- a]pyridin-3-yl)-3-[2- (1H...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373100 (1,3-bis(2-methyl-4- phenylpyrimidin-5- yl)urea | U...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373127 (1-[5-fluoro-2- (trifluoromethyl) benzyl]-3-(2-meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373123 (1-[4-fluoro-2- (trifluoromethyl) benzyl]-3-(1-phen...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373126 (1-(1-methyl-5- phenyl-1H-pyrazol- 4-yl)-3-[2- (tri...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373113 (1-(2- phenylimidazo[1,2- a]pyridin-3-yl)-3-(2- phe...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373131 (1-(1-methyl-5- phenyl-1H-pyrazol- 4-yl)-3-[2- (tri...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373110 (1-[3-(1-methyl-1H- imidazol-2- yl)phenyl]-3-(2- ph...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373093 (1-(3-methyl-1- phenyl-1H-pyrazol- 5-yl)-3-pyridin-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373120 (1-(2-methyl-4- phenyl-1,3-thiazol- 5-yl)-3-(2- phe...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373125 (1-[(1S)-1- cyclohexylethyl]-3- (2-methyl-4- phenyl...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373119 (1-(2-methyl-4- phenylpyrimidin-5- yl)-3-(2-methyl-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373096 (1-biphenyl-2-yl-3- (2-methyl-4- phenylpyrimidin-5-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373086 (1,3-bis(3-methyl-1- phenyl-1H-pyrazol- 5-yl)urea |...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373091 (1-(4-bromopyridin- 2-yl)-3-(3-methyl-1- phenyl-1H-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373094 (1-(5- methoxypyridin-2- yl)-3-(3-methyl-1- phenyl-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373116 (1-(1-methyl-4- phenyl-1H-imidazol- 5-yl)-3-(2-meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373103 (1-(2-methyl-4- phenylpyrimidin-5- yl)-3-pyridin-2-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373117 (1-(1,2-dimethyl-4- phenyl-1H-imidazol- 5-yl)-3-(2-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373098 (1-(2-methyl-4- phenylpyrimidin-5- yl)-3-naphthalen...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373105 (1-[2-chloro-4- (trifluoromethyl) phenyl]-3-(2- phe...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373106 (1-(2- phenylimidazo[1,2- a]pyridin-3-yl)-3-[4- (tr...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373088 (1-(6-bromopyridin- 2-yl)-3-(3-methyl-1- phenyl-1H-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM373090 (1-(2,3- dimethylphenyl)-3- (3-methyl-1-phenyl- 1H-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we... | J Med Chem 51: 861-74 (2008) BindingDB Entry DOI: 10.7270/Q26975VH | |||||||||||
More data for this Ligand-Target Pair |