Reaction Details | |||
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Target | Leucine-rich repeat serine/threonine-protein kinase 2 [1-1200,1251-2527,G2019S] | ||
Ligand | BDBM523030 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | LanthaScreen Assay | ||
IC50 | 0.800±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Leucine-rich repeat serine/threonine-protein kinase 2 [1-1200,1251-2527,G2019S] | |||
Name: | Leucine-rich repeat serine/threonine-protein kinase 2 [1-1200,1251-2527,G2019S] | ||
Synonyms: | LRRK2 | LRRK2_HUMAN | Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)(G2019S) | PARK8 | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 280290.60 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q5S007[1-1200,1251-2527,G2019S] | ||
Residue: | 2477 | ||
Sequence: |
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BDBM523030 | |||
n/a | |||
Name | BDBM523030 | ||
Synonyms: | US11161854, Example 2.5-1 | US11161854, Example 2.5-2 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H28N6O2 | ||
Mol. Mass. | 456.5395 | ||
SMILES | COc1nc(cc(n1)-n1ncc2ccc(cc12)C1(CC11CC1)C#N)N1CC2(CC1C2)C(C)(C)O |(-1.14,-4.36,;-1.62,-2.9,;-.59,-1.75,;.92,-2.07,;1.95,-.93,;1.47,.53,;-.03,.85,;-1.06,-.29,;-.51,2.32,;.4,3.57,;-.51,4.81,;-1.97,4.34,;-3.31,5.11,;-4.64,4.34,;-4.64,2.8,;-3.31,2.03,;-1.97,2.8,;-5.97,2.03,;-6.74,.69,;-5.2,.69,;-4.43,-.64,;-3.66,.69,;-7.06,3.11,;-8.15,4.2,;3.46,-1.25,;4.08,-2.66,;5.61,-2.5,;5.93,-.99,;4.6,-.22,;4.6,-1.76,;6.64,-3.64,;8.15,-3.32,;6.17,-5.11,;7.12,-2.18,)| | ||
Structure | ![]() |