| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Somatostatin receptor type 5 |
|---|
| Ligand | BDBM50468148 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1798207 (CHEMBL4270324) |
|---|
| IC50 | 43±n/a nM |
|---|
| Citation |  Liu, W; Hussain, Z; Zang, Y; Sweis, RF; Romero, FA; Finke, PE; Moningka, R; Bao, J; Plotkin, MA; Shang, J; Dingley, KH; Salituro, G; Murphy, BA; Howard, AD; Ujjainwalla, F; Wood, HB; Duffy, JL Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists. ACS Med Chem Lett9:1088-1093 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Somatostatin receptor type 5 |
|---|
| Name: | Somatostatin receptor type 5 |
|---|
| Synonyms: | SS-5-R | SS5-R | SS5R | SSR5_MOUSE | Smstr5 | Somatostatin receptor | Somatostatin receptor 5 | Somatostatin receptor type 5 | Sstr5 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 40022.97 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_833921 |
|---|
| Residue: | 362 |
|---|
| Sequence: | MEPLSLTSTPSWNASAASSSSHNWSLVDPVSPMGARAVLVPVLYLLVCTVGLGGNTLVIY
VVLRYAKMKTVTNVYILNLAVADVLFMLGLPFLATQNAVSYWPFGSFLCRLVMTLDGINQ
FTSIFCLMVMSVDRYLAVVHPLRSARWRRPRVAKLASAAVWVFSLLMSLPLLVFADVQEG
WGTCNLSWPEPVGLWGAAFITYTSVLGFFGPLLVICLCYLLIVVKVKAAGMRVGSSRRRR
SERKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPEEPTSAGLYFFVVVLSYANSCANP
LLYGFLSDNFRQSFRKALCLRRGYGVEDADAIEPRPDKSGRPQTTLPTRSCEANGLMQTS
RL
|
|
|
|---|
| BDBM50468148 |
|---|
| n/a |
|---|
| Name | BDBM50468148 |
|---|
| Synonyms: | CHEMBL4289325 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H25F3N2O4 |
|---|
| Mol. Mass. | 474.4722 |
|---|
| SMILES | OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3cc(ccc3C3CC3)C(F)(F)F)CC2)OC1=O |
|---|
| Structure | 
|
|---|
Search and Browse
