| Reaction Details |
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 | Report a problem with these data |
| Target | Spindlin-1 |
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| Ligand | BDBM50505578 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1823337 (CHEMBL4323101) |
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| Kd | 72±n/a nM |
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| Citation |  Fagan, V; Johansson, C; Gileadi, C; Monteiro, O; Dunford, JE; Nibhani, R; Philpott, M; Malzahn, J; Wells, G; Faram, R; Cribbs, AP; Halidi, N; Li, F; Chau, I; Greschik, H; Velupillai, S; Allali-Hassani, A; Bennett, J; Christott, T; Giroud, C; Lewis, AM; Huber, KVM; Athanasou, N; Bountra, C; Jung, M; Schüle, R; Vedadi, M; Arrowsmith, C; Xiong, Y; Jin, J; Fedorov, O; Farnie, G; Brennan, PE; Oppermann, U A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. J Med Chem62:9008-9025 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Spindlin-1 |
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| Name: | Spindlin-1 |
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| Synonyms: | OCR | Ovarian cancer-related protein | SPIN | SPIN1 | SPIN1_HUMAN | Spindlin-1 | Spindlin1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29602.24 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_119259 |
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| Residue: | 262 |
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| Sequence: | MKTPFGKTPGQRSRADAGHAGVSANMMKKRTSHKKHRSSVGPSKPVSQPRRNIVGCRIQH
GWKEGNGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELNKDERVSALEVLPDRVAT
SRISDAHLADTMIGKAVEHMFETEDGSKDEWRGMVLARAPVMNTWFYITYEKDPVLYMYQ
LLDDYKEGDLRIMPDSNDSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKP
SVYFIKFDDDFHIYVYDLVKTS
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| BDBM50505578 |
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| n/a |
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| Name | BDBM50505578 |
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| Synonyms: | CHEMBL4570122 |
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| Type | Small organic molecule |
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| Emp. Form. | C43H60N8O4 |
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| Mol. Mass. | 752.9877 |
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| SMILES | CC1(C)C(N)=Nc2cc(OCCCN3Cc4ccc(OCCc5cn(CCC(=O)N6CCC(CCN7CCCC7)CC6)nn5)cc4C3)c(OCC3CC3)cc12 |c:4| |
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| Structure | 
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