Reaction Details | |||
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Target | D(2) dopamine receptor | ||
Ligand | BDBM50063291 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_60370 (CHEMBL672206) | ||
Ki | 3.4±n/a nM | ||
Citation | Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Aminopyrimidines with high affinity for both serotonin and dopamine receptors. J Med Chem41:760-71 (1998) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
D(2) dopamine receptor | |||
Name: | D(2) dopamine receptor | ||
Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 | ||
Type: | Cell-surface receptors | ||
Mol. Mass.: | 50647.10 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P14416 | ||
Residue: | 443 | ||
Sequence: |
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BDBM50063291 | |||
n/a | |||
Name | BDBM50063291 | ||
Synonyms: | CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4-phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-amide | ||
Type | Small organic molecule | ||
Emp. Form. | C23H31N3OS | ||
Mol. Mass. | 397.577 | ||
SMILES | O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1cccs1 |wU:6.6,wD:3.2,(-4.1,-5.89,;-2.56,-5.89,;-1.79,-4.56,;-.25,-4.55,;.52,-5.88,;2.06,-5.86,;2.83,-4.53,;4.37,-4.53,;5.14,-3.2,;6.68,-3.16,;7.43,-1.82,;8.97,-1.78,;9.75,-3.1,;9.01,-4.44,;7.47,-4.46,;11.29,-3.06,;12.09,-4.39,;13.63,-4.36,;14.37,-3.01,;13.56,-1.69,;12.02,-1.73,;2.05,-3.2,;.51,-3.22,;-1.79,-7.22,;-.25,-7.3,;-.4,-9.95,;-1.93,-9.87,;-2.64,-8.5,)| | ||
Structure |