Compile Data Set for Download or QSAR

Found 261 hits with Last Name = 'corbin' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063292 (CHEMBL349426 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...) Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccccc12 |wU:17.22,wD:14.15,(10.31,-6.02,;11.15,-7.32,;12.69,-7.24,;13.39,-5.86,;14.93,-5.79,;15.76,-7.07,;15.07,-8.45,;13.53,-8.53,;17.3,-7,;17.99,-5.63,;19.5,-5.53,;20.36,-6.83,;19.66,-8.19,;18.13,-8.28,;8.79,-6.11,;7.95,-4.81,;6.42,-4.88,;5.72,-6.26,;6.55,-7.54,;8.09,-7.47,;4.18,-6.33,;3.34,-5.04,;4.04,-3.66,;3.23,-2.36,;1.69,-2.43,;.99,-3.81,;-.55,-3.87,;-1.26,-5.23,;-.44,-6.54,;1.1,-6.47,;1.8,-5.11,)| Show InChI InChI=1S/C26H33N5/c1-2-6-23(7-3-1)31-18-16-30(17-19-31)15-14-21-10-12-22(13-11-21)29-26-24-8-4-5-9-25(24)27-20-28-26/h1-9,20-22H,10-19H2,(H,27,28,29)/t21-,22-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cells				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (MOUSE)	BDBM50286859 (2-{2-[(S)-2-({1-[(S)-6-Amino-2-((S)-(S)-2,6-diamin...) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCN)NC[C@@H](N)CCCCN)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C40H67N9O6/c1-5-26(4)35(38(52)47-33(40(54)55)21-25(2)3)48-36(50)32(22-27-23-44-30-15-7-6-14-29(27)30)46-37(51)34-17-12-20-49(34)39(53)31(16-9-11-19-42)45-24-28(43)13-8-10-18-41/h6-7,14-15,23,25-26,28,31-35,44-45H,5,8-13,16-22,24,41-43H2,1-4H3,(H,46,51)(H,47,52)(H,48,50)(H,54,55)/t26-,28-,31-,32-,33-,34+,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Neurotensin Receptor				Bioorg Med Chem Lett 5: 997-1002 (1995) Article DOI: 10.1016/0960-894X(95)00155-M BindingDB Entry DOI: 10.7270/Q2GQ6Z76
					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (MOUSE)	BDBM50240339 ((S)-2-((S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)-5-g...) Show SMILES CN[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(O)=O)C(C)(C)C |r,wU:2.1,43.45,wD:25.26,29.29,47.49,13.12,(-9.76,-17.57,;-8.43,-18.35,;-7.09,-17.6,;-7.09,-16.06,;-8.41,-15.28,;-8.4,-13.73,;-9.73,-12.95,;-9.72,-11.41,;-11.06,-10.63,;-8.38,-10.64,;-5.76,-18.38,;-5.77,-19.91,;-4.42,-17.61,;-3.09,-18.39,;-3.1,-19.93,;-4.44,-20.7,;-4.45,-22.24,;-5.78,-23,;-5.8,-24.54,;-1.74,-17.63,;-1.73,-16.1,;-.42,-18.41,;-0,-19.94,;1.55,-19.94,;2.08,-18.51,;.87,-17.56,;.94,-16,;-.36,-15.18,;2.3,-15.29,;3.6,-16.11,;3.53,-17.65,;4.83,-18.49,;6.26,-17.92,;7.23,-19.11,;6.4,-20.41,;6.81,-21.89,;5.72,-22.98,;4.24,-22.59,;3.84,-21.1,;4.92,-20.02,;4.97,-15.4,;5.05,-13.86,;6.27,-16.23,;7.64,-15.53,;8.93,-16.36,;8.86,-17.9,;10.3,-15.65,;11.59,-16.49,;11.52,-18.02,;12.82,-18.86,;12.82,-20.4,;14.19,-18.15,;12.96,-15.78,;14.25,-16.61,;13.04,-14.25,;7.72,-13.99,;7.71,-12.44,;9.26,-14.02,;6.18,-13.96,)| Show InChI InChI=1S/C41H67N11O7/c1-24(2)21-31(39(58)59)50-37(56)33(41(3,4)5)51-35(54)30(22-25-23-47-27-14-8-7-13-26(25)27)49-36(55)32-17-12-20-52(32)38(57)29(15-9-10-18-42)48-34(53)28(45-6)16-11-19-46-40(43)44/h7-8,13-14,23-24,28-33,45,47H,9-12,15-22,42H2,1-6H3,(H,48,53)(H,49,55)(H,50,56)(H,51,54)(H,58,59)(H4,43,44,46)/t28-,29-,30-,31-,32-,33+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.0640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administration				Bioorg Med Chem Lett 5: 997-1002 (1995) Article DOI: 10.1016/0960-894X(95)00155-M BindingDB Entry DOI: 10.7270/Q2GQ6Z76
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...) Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [3H]- prazosin binding against Alpha-1A adrenergic receptor from rat submaxillary gland				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (MOUSE)	BDBM50286864 ((S)-2-{(S)-2-[(S)-2-({(R)-1-[5-Guanidino-2-(3-guan...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1CCCN1C(=O)C(CCCNC(N)=N)CCCNC(N)=N)C(C)(C)C)C(O)=O Show InChI InChI=1S/C38H61N11O6/c1-22(2)19-28(35(54)55)47-33(52)30(38(3,4)5)48-31(50)27(20-24-21-45-26-14-7-6-13-25(24)26)46-32(51)29-15-10-18-49(29)34(53)23(11-8-16-43-36(39)40)12-9-17-44-37(41)42/h6-7,13-14,21-23,27-30,45H,8-12,15-20H2,1-5H3,(H,46,51)(H,47,52)(H,48,50)(H,54,55)(H4,39,40,43)(H4,41,42,44)/t27-,28-,29+,30+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Neurotensin Receptor				Bioorg Med Chem Lett 5: 997-1002 (1995) Article DOI: 10.1016/0960-894X(95)00155-M BindingDB Entry DOI: 10.7270/Q2GQ6Z76
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063279 (CHEMBL309623 | Cyclohexanecarboxylic acid {4-[2-(4...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)C1CCCCC1 |wU:6.6,wD:3.2,(1.34,-9.45,;2.88,-9.43,;3.66,-8.1,;5.2,-8.1,;5.97,-9.43,;7.51,-9.42,;8.29,-8.08,;9.83,-8.08,;10.6,-6.74,;12.14,-6.71,;12.89,-5.36,;14.44,-5.33,;15.22,-6.65,;14.48,-7.98,;12.94,-8.02,;16.77,-6.62,;17.56,-7.94,;19.09,-7.91,;19.85,-6.56,;19.04,-5.22,;17.5,-5.27,;7.51,-6.76,;5.96,-6.77,;3.66,-10.76,;5.19,-10.76,;5.95,-12.1,;5.18,-13.42,;3.66,-13.42,;2.88,-12.1,)| Show InChI InChI=1S/C25H39N3O/c29-25(22-7-3-1-4-8-22)26-23-13-11-21(12-14-23)15-16-27-17-19-28(20-18-27)24-9-5-2-6-10-24/h2,5-6,9-10,21-23H,1,3-4,7-8,11-20H2,(H,26,29)/t21-,23-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cells				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Rattus norvegicus (rat))	BDBM29568 (CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...) Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [3H]- prazosin binding against Alpha-1B adrenergic receptor from rat liver				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (MOUSE)	BDBM50366427 (CHEMBL1793865) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCN)NC[C@@H](N)CCCCN)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C38H66N8O7/c1-5-25(4)33(36(50)44-31(38(52)53)21-24(2)3)45-34(48)30(22-26-14-16-28(47)17-15-26)43-35(49)32-13-10-20-46(32)37(51)29(12-7-9-19-40)42-23-27(41)11-6-8-18-39/h14-17,24-25,27,29-33,42,47H,5-13,18-23,39-41H2,1-4H3,(H,43,49)(H,44,50)(H,45,48)(H,52,53)/t25-,27-,29-,30-,31-,32+,33-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Neurotensin Receptor				Bioorg Med Chem Lett 5: 997-1002 (1995) Article DOI: 10.1016/0960-894X(95)00155-M BindingDB Entry DOI: 10.7270/Q2GQ6Z76
					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (MOUSE)	BDBM50286868 ((1S,2S,4S)-2-{2-[(S)-2-({1-[6-Amino-2-(2,6-diamino...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCN)NC[C@@H](N)CCCCN)C(C)(C)C)C(O)=O Show InChI InChI=1S/C38H66N8O7/c1-24(2)21-30(37(52)53)44-35(50)32(38(3,4)5)45-33(48)29(22-25-14-16-27(47)17-15-25)43-34(49)31-13-10-20-46(31)36(51)28(12-7-9-19-40)42-23-26(41)11-6-8-18-39/h14-17,24,26,28-32,42,47H,6-13,18-23,39-41H2,1-5H3,(H,43,49)(H,44,50)(H,45,48)(H,52,53)/t26-,28-,29-,30-,31+,32+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Neurotensin Receptor				Bioorg Med Chem Lett 5: 997-1002 (1995) Article DOI: 10.1016/0960-894X(95)00155-M BindingDB Entry DOI: 10.7270/Q2GQ6Z76
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50063281 ((4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}...) Show SMILES COc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 |wU:17.21,wD:14.14,(16.78,-2.98,;16.09,-4.37,;16.94,-5.65,;18.47,-5.56,;19.33,-6.85,;18.62,-8.23,;17.09,-8.3,;16.26,-7.01,;14.71,-7.11,;14.02,-8.49,;12.47,-8.56,;11.63,-7.27,;10.08,-7.34,;9.24,-6.05,;7.71,-6.12,;6.86,-4.83,;5.33,-4.9,;4.62,-6.29,;5.46,-7.57,;7,-7.5,;3.07,-6.36,;2.23,-5.04,;2.95,-3.69,;2.11,-2.37,;.56,-2.44,;-.14,-3.83,;.7,-5.14,;12.33,-5.89,;13.87,-5.82,)| Show InChI InChI=1S/C23H33N5O/c1-29-22-6-3-2-5-21(22)28-17-15-27(16-18-28)14-11-19-7-9-20(10-8-19)26-23-24-12-4-13-25-23/h2-6,12-13,19-20H,7-11,14-18H2,1H3,(H,24,25,26)/t19-,20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (MOUSE)	BDBM50240845 ((S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amin...) Show SMILES [#6]-[#6]-[#6@@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](-[#8])=O |r| Show InChI InChI=1S/C38H64N12O8/c1-5-22(4)30(34(55)48-28(36(57)58)19-21(2)3)49-32(53)27(20-23-12-14-24(51)15-13-23)47-33(54)29-11-8-18-50(29)35(56)26(10-7-17-45-38(42)43)46-31(52)25(39)9-6-16-44-37(40)41/h12-15,21-22,25-30,51H,5-11,16-20,39H2,1-4H3,(H,46,52)(H,47,54)(H,48,55)(H,49,53)(H,57,58)(H4,40,41,44)(H4,42,43,45)/t22-,25+,26+,27+,28+,29+,30+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Neurotensin Receptor				Bioorg Med Chem Lett 5: 997-1002 (1995) Article DOI: 10.1016/0960-894X(95)00155-M BindingDB Entry DOI: 10.7270/Q2GQ6Z76
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020221 ((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...) Show SMILES CCCN(CCC)C1CCc2c(O)cccc2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity of the compound is the ability to displace [3H]-spiperone from human Dopamine receptor D3 expressed in CHO-K1 cells.				J Med Chem 38: 3132-7 (1995) BindingDB Entry DOI: 10.7270/Q28W3C9S
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063291 (CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1cccs1 |wU:6.6,wD:3.2,(-4.1,-5.89,;-2.56,-5.89,;-1.79,-4.56,;-.25,-4.55,;.52,-5.88,;2.06,-5.86,;2.83,-4.53,;4.37,-4.53,;5.14,-3.2,;6.68,-3.16,;7.43,-1.82,;8.97,-1.78,;9.75,-3.1,;9.01,-4.44,;7.47,-4.46,;11.29,-3.06,;12.09,-4.39,;13.63,-4.36,;14.37,-3.01,;13.56,-1.69,;12.02,-1.73,;2.05,-3.2,;.51,-3.22,;-1.79,-7.22,;-.25,-7.3,;-.4,-9.95,;-1.93,-9.87,;-2.64,-8.5,)| Show InChI InChI=1S/C23H31N3OS/c27-23(22-7-4-18-28-22)24-20-10-8-19(9-11-20)12-13-25-14-16-26(17-15-25)21-5-2-1-3-6-21/h1-7,18-20H,8-17H2,(H,24,27)/t19-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cells				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50032644 (CHEMBL110888 | N*6*,N*6*-Dipropyl-5,6,7,8-tetrahyd...) Show SMILES CCCN(CCC)C1CCc2nc(N)ccc2C1 Show InChI InChI=1S/C15H25N3/c1-3-9-18(10-4-2)13-6-7-14-12(11-13)5-8-15(16)17-14/h5,8,13H,3-4,6-7,9-11H2,1-2H3,(H2,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity of the compound is the ability to displace [3H]-spiperone from human Dopamine receptor D3 expressed in CHO-K1 cells.				J Med Chem 38: 3132-7 (1995) BindingDB Entry DOI: 10.7270/Q28W3C9S
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM85093 (CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM85093 (CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro binding affinity at human dopamine D4 receptor expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 8: 1499-502 (1999) BindingDB Entry DOI: 10.7270/Q2WH2P54
					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (MOUSE)	BDBM50286866 (2-{2-[(S)-2-({1-[(S)-6-Amino-2-((S)-2,6-diamino-he...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCN)NC[C@@H](N)CCCCN)C(C)(C)C)C(O)=O Show InChI InChI=1S/C40H67N9O6/c1-25(2)21-32(39(54)55)47-37(52)34(40(3,4)5)48-35(50)31(22-26-23-44-29-15-7-6-14-28(26)29)46-36(51)33-17-12-20-49(33)38(53)30(16-9-11-19-42)45-24-27(43)13-8-10-18-41/h6-7,14-15,23,25,27,30-34,44-45H,8-13,16-22,24,41-43H2,1-5H3,(H,46,51)(H,47,52)(H,48,50)(H,54,55)/t27-,30-,31-,32-,33+,34+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Neurotensin Receptor				Bioorg Med Chem Lett 5: 997-1002 (1995) Article DOI: 10.1016/0960-894X(95)00155-M BindingDB Entry DOI: 10.7270/Q2GQ6Z76
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083349 (6-[4-(3,4-Dimethyl-phenyl)-piperidin-1-ylmethyl]-4...) Show SMILES Cc1ccc(cc1C)C1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C22H26N2O2/c1-15-3-5-19(11-16(15)2)18-7-9-24(10-8-18)13-17-4-6-21-20(12-17)23-22(25)14-26-21/h3-6,11-12,18H,7-10,13-14H2,1-2H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [3H]- pentazocine binding against alpha-1 from guinea pig brain				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50032643 (CHEMBL105512 | N*6*,N*6*-Dipropyl-4,5,6,7-tetrahyd...) Show SMILES CCCN(CCC)C1CCc2nc(N)sc2C1 Show InChI InChI=1S/C13H23N3S/c1-3-7-16(8-4-2)10-5-6-11-12(9-10)17-13(14)15-11/h10H,3-9H2,1-2H3,(H2,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity of the compound is the ability to displace [3H]-spiperone from human Dopamine receptor D3 expressed in CHO-K1 cells				J Med Chem 38: 3132-7 (1995) BindingDB Entry DOI: 10.7270/Q28W3C9S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50455438 (CHEMBL3084971) Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@H](CC1)Nc1ncccn1 |wU:17.22,14.15,(9.21,-6,;10.05,-7.3,;11.58,-7.21,;12.42,-8.52,;13.96,-8.42,;14.64,-7.05,;13.8,-5.77,;12.28,-5.84,;16.18,-6.98,;17.02,-8.26,;18.53,-8.17,;19.23,-6.81,;18.39,-5.51,;16.85,-5.6,;7.67,-6.09,;6.97,-7.44,;5.43,-7.51,;4.59,-6.23,;5.31,-4.86,;6.83,-4.79,;3.05,-6.3,;2.21,-5.02,;.7,-5.09,;-.14,-3.81,;.56,-2.43,;2.1,-2.36,;2.94,-3.64,)| Show InChI InChI=1S/C22H31N5/c1-2-5-21(6-3-1)27-17-15-26(16-18-27)14-11-19-7-9-20(10-8-19)25-22-23-12-4-13-24-22/h1-6,12-13,19-20H,7-11,14-18H2,(H,23,24,25)/t19-,20+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (NEONATAL RAT)	BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [3H]- Yohimbine binding against rat kidney cortex Alpha-2B adrenergic receptor				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50063280 (CHEMBL355371 | {4-[2-(4-Pyridin-2-yl-piperazin-1-y...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,(9.19,-6.02,;10.03,-7.31,;11.57,-7.24,;12.41,-8.52,;13.95,-8.45,;14.64,-7.07,;13.8,-5.79,;12.27,-5.86,;16.18,-6.98,;17,-8.26,;18.54,-8.19,;19.23,-6.82,;18.38,-5.53,;16.86,-5.63,;7.67,-6.09,;6.83,-4.81,;5.3,-4.88,;4.59,-6.26,;5.43,-7.54,;6.97,-7.47,;3.05,-6.33,;2.21,-5.02,;.7,-5.11,;-.14,-3.81,;.56,-2.43,;2.1,-2.36,;2.94,-3.67,)| Show InChI InChI=1S/C21H30N6/c1-2-10-22-20(4-1)27-16-14-26(15-17-27)13-9-18-5-7-19(8-6-18)25-21-23-11-3-12-24-21/h1-4,10-12,18-19H,5-9,13-17H2,(H,23,24,25)/t18-,19-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083337 (7-[4-(3,4-Dimethyl-phenyl)-piperidin-1-ylmethyl]-4...) Show SMILES Cc1ccc(cc1C)C1CCN(Cc2ccc3NC(=O)COc3c2)CC1 Show InChI InChI=1S/C22H26N2O2/c1-15-3-5-19(11-16(15)2)18-7-9-24(10-8-18)13-17-4-6-20-21(12-17)26-14-22(25)23-20/h3-6,11-12,18H,7-10,13-14H2,1-2H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083341 (7-(4-p-Tolyl-piperidin-1-ylmethyl)-4H-benzo[1,4]ox...) Show SMILES Cc1ccc(cc1)C1CCN(Cc2ccc3NC(=O)COc3c2)CC1 Show InChI InChI=1S/C21H24N2O2/c1-15-2-5-17(6-3-15)18-8-10-23(11-9-18)13-16-4-7-19-20(12-16)25-14-21(24)22-19/h2-7,12,18H,8-11,13-14H2,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50055721 (3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12 |wU:17.22,wD:14.15,(13.38,-6.36,;14.69,-7.13,;16.04,-6.36,;17.37,-7.13,;18.7,-6.36,;18.68,-4.79,;17.33,-4.05,;16.01,-4.82,;20.02,-4.02,;21.34,-4.79,;22.68,-4.02,;22.66,-2.48,;21.33,-1.71,;19.99,-2.48,;12.03,-7.1,;10.72,-6.33,;9.37,-7.1,;9.38,-8.64,;10.72,-9.41,;12.03,-8.64,;8.1,-9.47,;8.02,-11.01,;6.54,-11.43,;5.68,-10.15,;4.15,-9.92,;3.59,-8.48,;4.59,-7.29,;6.1,-7.52,;6.64,-8.96,)| Show InChI InChI=1S/C25H32N4/c1-2-6-24-22(5-1)23(19-27-24)21-10-8-20(9-11-21)12-14-28-15-17-29(18-16-28)25-7-3-4-13-26-25/h1-7,13,19-21,27H,8-12,14-18H2/t20-,21-	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Division of Warner Lambert Company Curated by ChEMBL					Assay Description Binding affinity was determined in vitro on rat striatum using [3H]-N-propylnorapomorphine against Dopamine receptor D2				J Med Chem 40: 250-9 (1997) Article DOI: 10.1021/jm960597m BindingDB Entry DOI: 10.7270/Q28W3CD4
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083350 (6-(4-p-Tolyl-piperidin-1-ylmethyl)-4H-benzo[1,4]ox...) Show SMILES Cc1ccc(cc1)C1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C21H24N2O2/c1-15-2-5-17(6-3-15)18-8-10-23(11-9-18)13-16-4-7-20-19(12-16)22-21(24)14-25-20/h2-7,12,18H,8-11,13-14H2,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063281 ((4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}...) Show SMILES COc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 |wU:17.21,wD:14.14,(16.78,-2.98,;16.09,-4.37,;16.94,-5.65,;18.47,-5.56,;19.33,-6.85,;18.62,-8.23,;17.09,-8.3,;16.26,-7.01,;14.71,-7.11,;14.02,-8.49,;12.47,-8.56,;11.63,-7.27,;10.08,-7.34,;9.24,-6.05,;7.71,-6.12,;6.86,-4.83,;5.33,-4.9,;4.62,-6.29,;5.46,-7.57,;7,-7.5,;3.07,-6.36,;2.23,-5.04,;2.95,-3.69,;2.11,-2.37,;.56,-2.44,;-.14,-3.83,;.7,-5.14,;12.33,-5.89,;13.87,-5.82,)| Show InChI InChI=1S/C23H33N5O/c1-29-22-6-3-2-5-21(22)28-17-15-27(16-18-28)14-11-19-7-9-20(10-8-19)26-23-24-12-4-13-25-23/h2-6,12-13,19-20H,7-11,14-18H2,1H3,(H,24,25,26)/t19-,20-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [3H]- MK-912 binding against human recombinant Alpha-2A adrenergic receptor				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063292 (CHEMBL349426 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...) Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccccc12 |wU:17.22,wD:14.15,(10.31,-6.02,;11.15,-7.32,;12.69,-7.24,;13.39,-5.86,;14.93,-5.79,;15.76,-7.07,;15.07,-8.45,;13.53,-8.53,;17.3,-7,;17.99,-5.63,;19.5,-5.53,;20.36,-6.83,;19.66,-8.19,;18.13,-8.28,;8.79,-6.11,;7.95,-4.81,;6.42,-4.88,;5.72,-6.26,;6.55,-7.54,;8.09,-7.47,;4.18,-6.33,;3.34,-5.04,;4.04,-3.66,;3.23,-2.36,;1.69,-2.43,;.99,-3.81,;-.55,-3.87,;-1.26,-5.23,;-.44,-6.54,;1.1,-6.47,;1.8,-5.11,)| Show InChI InChI=1S/C26H33N5/c1-2-6-23(7-3-1)31-18-16-30(17-19-31)15-14-21-10-12-22(13-11-21)29-26-24-8-4-5-9-25(24)27-20-28-26/h1-9,20-22H,10-19H2,(H,27,28,29)/t21-,22-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063291 (CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1cccs1 |wU:6.6,wD:3.2,(-4.1,-5.89,;-2.56,-5.89,;-1.79,-4.56,;-.25,-4.55,;.52,-5.88,;2.06,-5.86,;2.83,-4.53,;4.37,-4.53,;5.14,-3.2,;6.68,-3.16,;7.43,-1.82,;8.97,-1.78,;9.75,-3.1,;9.01,-4.44,;7.47,-4.46,;11.29,-3.06,;12.09,-4.39,;13.63,-4.36,;14.37,-3.01,;13.56,-1.69,;12.02,-1.73,;2.05,-3.2,;.51,-3.22,;-1.79,-7.22,;-.25,-7.3,;-.4,-9.95,;-1.93,-9.87,;-2.64,-8.5,)| Show InChI InChI=1S/C23H31N3OS/c27-23(22-7-4-18-28-22)24-20-10-8-19(9-11-20)12-13-25-14-16-26(17-15-25)21-5-2-1-3-6-21/h1-7,18-20H,8-17H2,(H,24,27)/t19-,20-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50063296 (CHEMBL165679 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...) Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,(9.21,-6.02,;10.05,-7.32,;11.59,-7.24,;12.43,-8.53,;13.97,-8.45,;14.66,-7.08,;13.82,-5.79,;12.29,-5.86,;16.2,-6.99,;17.03,-8.27,;18.56,-8.18,;19.26,-6.83,;18.41,-5.53,;16.88,-5.63,;7.68,-6.1,;6.84,-4.81,;5.31,-4.88,;4.6,-6.26,;5.44,-7.54,;6.98,-7.47,;3.06,-6.33,;2.22,-5.03,;.7,-5.11,;-.14,-3.81,;.56,-2.44,;2.1,-2.37,;2.94,-3.67,)| Show InChI InChI=1S/C22H31N5/c1-2-5-21(6-3-1)27-17-15-26(16-18-27)14-11-19-7-9-20(10-8-19)25-22-23-12-4-13-24-22/h1-6,12-13,19-20H,7-11,14-18H2,(H,23,24,25)/t19-,20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063276 (CHEMBL164604 | {4-[2-(4-Phenyl-3,6-dihydro-2H-pyri...) Show SMILES C(CN1CCC(=CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,c:5,(9.23,-6.05,;10.08,-7.34,;11.62,-7.27,;12.47,-8.55,;14.01,-8.48,;14.71,-7.1,;13.86,-5.82,;12.33,-5.89,;16.25,-7.01,;17.08,-8.3,;18.62,-8.23,;19.32,-6.85,;18.46,-5.56,;16.93,-5.65,;7.7,-6.12,;6.86,-4.83,;5.32,-4.9,;4.61,-6.28,;5.46,-7.57,;7,-7.5,;3.07,-6.35,;2.22,-5.04,;.7,-5.14,;-.14,-3.82,;.56,-2.44,;2.11,-2.37,;2.95,-3.68,)| Show InChI InChI=1S/C23H30N4/c1-2-5-20(6-3-1)21-12-17-27(18-13-21)16-11-19-7-9-22(10-8-19)26-23-24-14-4-15-25-23/h1-6,12,14-15,19,22H,7-11,13,16-18H2,(H,24,25,26)/t19-,22-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cells				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (MOUSE)	BDBM50286861 ((S)-2-{(S)-2-[(S)-2-({(R)-1-[6-Amino-2-(4-amino-bu...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1CCCN1C(=O)C(CCCCN)CCCCN)C(C)(C)C)C(O)=O Show InChI InChI=1S/C38H61N7O6/c1-24(2)21-30(37(50)51)43-35(48)32(38(3,4)5)44-33(46)29(22-26-23-41-28-16-7-6-15-27(26)28)42-34(47)31-17-12-20-45(31)36(49)25(13-8-10-18-39)14-9-11-19-40/h6-7,15-16,23-25,29-32,41H,8-14,17-22,39-40H2,1-5H3,(H,42,47)(H,43,48)(H,44,46)(H,50,51)/t29-,30-,31+,32+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Neurotensin Receptor				Bioorg Med Chem Lett 5: 997-1002 (1995) Article DOI: 10.1016/0960-894X(95)00155-M BindingDB Entry DOI: 10.7270/Q2GQ6Z76
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083339 (6-[4-(4-Methoxy-phenyl)-piperidin-1-ylmethyl]-4H-b...) Show SMILES COc1ccc(cc1)C1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C21H24N2O3/c1-25-18-5-3-16(4-6-18)17-8-10-23(11-9-17)13-15-2-7-20-19(12-15)22-21(24)14-26-20/h2-7,12,17H,8-11,13-14H2,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50063276 (CHEMBL164604 | {4-[2-(4-Phenyl-3,6-dihydro-2H-pyri...) Show SMILES C(CN1CCC(=CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,c:5,(9.23,-6.05,;10.08,-7.34,;11.62,-7.27,;12.47,-8.55,;14.01,-8.48,;14.71,-7.1,;13.86,-5.82,;12.33,-5.89,;16.25,-7.01,;17.08,-8.3,;18.62,-8.23,;19.32,-6.85,;18.46,-5.56,;16.93,-5.65,;7.7,-6.12,;6.86,-4.83,;5.32,-4.9,;4.61,-6.28,;5.46,-7.57,;7,-7.5,;3.07,-6.35,;2.22,-5.04,;.7,-5.14,;-.14,-3.82,;.56,-2.44,;2.11,-2.37,;2.95,-3.68,)| Show InChI InChI=1S/C23H30N4/c1-2-5-20(6-3-1)21-12-17-27(18-13-21)16-11-19-7-9-22(10-8-19)26-23-24-14-4-15-25-23/h1-6,12,14-15,19,22H,7-11,13,16-18H2,(H,24,25,26)/t19-,22-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083342 (7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-be...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2ccc3NC(=O)COc3c2)CC1 Show InChI InChI=1S/C19H20ClN3O2/c20-15-2-4-16(5-3-15)23-9-7-22(8-10-23)12-14-1-6-17-18(11-14)25-13-19(24)21-17/h1-6,11H,7-10,12-13H2,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083338 (6-(4-p-Tolyl-piperazin-1-ylmethyl)-4H-benzo[1,4]ox...) Show SMILES Cc1ccc(cc1)N1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C20H23N3O2/c1-15-2-5-17(6-3-15)23-10-8-22(9-11-23)13-16-4-7-19-18(12-16)21-20(24)14-25-19/h2-7,12H,8-11,13-14H2,1H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50063277 ((4-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-...) Show SMILES Fc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 |wU:16.20,wD:13.13,(20.1,-6.75,;18.55,-6.85,;17.69,-5.56,;16.16,-5.65,;15.48,-7.01,;16.31,-8.3,;17.85,-8.23,;13.94,-7.11,;13.24,-8.49,;11.7,-8.56,;10.85,-7.27,;9.31,-7.34,;8.46,-6.05,;6.93,-6.12,;6.09,-4.83,;4.55,-4.9,;3.84,-6.29,;4.69,-7.57,;6.23,-7.5,;2.3,-6.36,;1.45,-5.04,;2.18,-3.69,;1.34,-2.37,;-.21,-2.44,;-.91,-3.83,;-.07,-5.14,;11.56,-5.89,;13.09,-5.82,)| Show InChI InChI=1S/C22H30FN5/c23-19-4-8-21(9-5-19)28-16-14-27(15-17-28)13-10-18-2-6-20(7-3-18)26-22-24-11-1-12-25-22/h1,4-5,8-9,11-12,18,20H,2-3,6-7,10,13-17H2,(H,24,25,26)/t18-,20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50063288 (CHEMBL165047 | Methyl-{4-[2-(4-phenyl-piperazin-1-...) Show SMILES CN([C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1ncccn1 |wU:2.1,wD:5.5,(2.36,-7.7,;3.06,-6.33,;4.6,-6.26,;5.31,-4.88,;6.85,-4.81,;7.69,-6.11,;9.22,-6.03,;10.06,-7.32,;11.6,-7.25,;12.3,-5.87,;13.84,-5.8,;14.68,-7.08,;13.98,-8.46,;12.44,-8.54,;16.22,-7,;16.9,-5.63,;18.43,-5.54,;19.28,-6.83,;18.58,-8.19,;17.05,-8.28,;6.99,-7.48,;5.45,-7.55,;2.22,-5.03,;.7,-5.12,;-.14,-3.82,;.56,-2.44,;2.1,-2.37,;2.94,-3.67,)| Show InChI InChI=1S/C23H33N5/c1-26(23-24-13-5-14-25-23)21-10-8-20(9-11-21)12-15-27-16-18-28(19-17-27)22-6-3-2-4-7-22/h2-7,13-14,20-21H,8-12,15-19H2,1H3/t20-,21-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063276 (CHEMBL164604 | {4-[2-(4-Phenyl-3,6-dihydro-2H-pyri...) Show SMILES C(CN1CCC(=CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,c:5,(9.23,-6.05,;10.08,-7.34,;11.62,-7.27,;12.47,-8.55,;14.01,-8.48,;14.71,-7.1,;13.86,-5.82,;12.33,-5.89,;16.25,-7.01,;17.08,-8.3,;18.62,-8.23,;19.32,-6.85,;18.46,-5.56,;16.93,-5.65,;7.7,-6.12,;6.86,-4.83,;5.32,-4.9,;4.61,-6.28,;5.46,-7.57,;7,-7.5,;3.07,-6.35,;2.22,-5.04,;.7,-5.14,;-.14,-3.82,;.56,-2.44,;2.11,-2.37,;2.95,-3.68,)| Show InChI InChI=1S/C23H30N4/c1-2-5-20(6-3-1)21-12-17-27(18-13-21)16-11-19-7-9-22(10-8-19)26-23-24-14-4-15-25-23/h1-6,12,14-15,19,22H,7-11,13,16-18H2,(H,24,25,26)/t19-,22-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063286 (CHEMBL164723 | {4-[2-(4-Pyridin-3-yl-piperazin-1-y...) Show SMILES C(CN1CCN(CC1)c1cccnc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,(9.24,-6.05,;10.08,-7.34,;11.63,-7.27,;12.47,-8.56,;14.02,-8.49,;14.71,-7.11,;13.87,-5.82,;12.33,-5.89,;16.26,-7.01,;17.09,-8.3,;18.62,-8.23,;19.33,-6.85,;18.47,-5.56,;16.94,-5.65,;7.71,-6.12,;6.86,-4.83,;5.33,-4.9,;4.62,-6.29,;5.46,-7.57,;7,-7.5,;3.07,-6.36,;2.23,-5.04,;.7,-5.14,;-.14,-3.83,;.56,-2.44,;2.11,-2.37,;2.95,-3.69,)| Show InChI InChI=1S/C21H30N6/c1-3-20(17-22-9-1)27-15-13-26(14-16-27)12-8-18-4-6-19(7-5-18)25-21-23-10-2-11-24-21/h1-3,9-11,17-19H,4-8,12-16H2,(H,23,24,25)/t18-,19-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cells				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063288 (CHEMBL165047 | Methyl-{4-[2-(4-phenyl-piperazin-1-...) Show SMILES CN([C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1ncccn1 |wU:2.1,wD:5.5,(2.36,-7.7,;3.06,-6.33,;4.6,-6.26,;5.31,-4.88,;6.85,-4.81,;7.69,-6.11,;9.22,-6.03,;10.06,-7.32,;11.6,-7.25,;12.3,-5.87,;13.84,-5.8,;14.68,-7.08,;13.98,-8.46,;12.44,-8.54,;16.22,-7,;16.9,-5.63,;18.43,-5.54,;19.28,-6.83,;18.58,-8.19,;17.05,-8.28,;6.99,-7.48,;5.45,-7.55,;2.22,-5.03,;.7,-5.12,;-.14,-3.82,;.56,-2.44,;2.1,-2.37,;2.94,-3.67,)| Show InChI InChI=1S/C23H33N5/c1-26(23-24-13-5-14-25-23)21-10-8-20(9-11-21)12-15-27-16-18-28(19-17-27)22-6-3-2-4-7-22/h2-7,13-14,20-21H,8-12,15-19H2,1H3/t20-,21-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063298 ((4-{2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-eth...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)Nc3ncccn3)CC2)c1Cl |wU:15.18,wD:12.11,(19.11,-4.18,;18.42,-5.56,;19.28,-6.84,;18.57,-8.23,;17.04,-8.3,;16.21,-7.01,;14.66,-7.1,;13.82,-5.81,;12.29,-5.88,;11.59,-7.27,;10.04,-7.34,;9.2,-6.05,;7.66,-6.12,;6.82,-4.83,;5.29,-4.9,;4.57,-6.28,;5.42,-7.57,;6.96,-7.5,;3.03,-6.35,;2.19,-5.04,;.66,-5.13,;-.18,-3.82,;.52,-2.44,;2.07,-2.37,;2.91,-3.68,;12.43,-8.55,;13.98,-8.48,;16.89,-5.65,;16.04,-4.36,)| Show InChI InChI=1S/C22H29Cl2N5/c23-19-3-1-4-20(21(19)24)29-15-13-28(14-16-29)12-9-17-5-7-18(8-6-17)27-22-25-10-2-11-26-22/h1-4,10-11,17-18H,5-9,12-16H2,(H,25,26,27)/t17-,18-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cells				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50032641 (CHEMBL105977 | Dipropyl-(5,6,7,8-tetrahydro-quinol...) Show SMILES CCCN(CCC)C1CCc2ncccc2C1 Show InChI InChI=1S/C15H24N2/c1-3-10-17(11-4-2)14-7-8-15-13(12-14)6-5-9-16-15/h5-6,9,14H,3-4,7-8,10-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity of the compound is the ability to displace [3H]-spiperone from human Dopamine receptor D3 expressed in CHO-K1 cells.				J Med Chem 38: 3132-7 (1995) BindingDB Entry DOI: 10.7270/Q28W3C9S
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50032644 (CHEMBL110888 | N*6*,N*6*-Dipropyl-5,6,7,8-tetrahyd...) Show SMILES CCCN(CCC)C1CCc2nc(N)ccc2C1 Show InChI InChI=1S/C15H25N3/c1-3-9-18(10-4-2)13-6-7-14-12(11-13)5-8-15(16)17-14/h5,8,13H,3-4,6-7,9-11H2,1-2H3,(H2,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity of the compound is the ability to displace [3H]-N-0437 from human Dopamine receptor D2 expressed in CHO-K1 cells				J Med Chem 38: 3132-7 (1995) BindingDB Entry DOI: 10.7270/Q28W3C9S
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083345 (7-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-4H-b...) Show SMILES COc1ccc(cc1)N1CCN(Cc2ccc3NC(=O)COc3c2)CC1 Show InChI InChI=1S/C20H23N3O3/c1-25-17-5-3-16(4-6-17)23-10-8-22(9-11-23)13-15-2-7-18-19(12-15)26-14-20(24)21-18/h2-7,12H,8-11,13-14H2,1H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083340 (6-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-4...) Show SMILES Cc1ccc(cc1C)N1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C21H25N3O2/c1-15-3-5-18(11-16(15)2)24-9-7-23(8-10-24)13-17-4-6-20-19(12-17)22-21(25)14-26-20/h3-6,11-12H,7-10,13-14H2,1-2H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063296 (CHEMBL165679 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...) Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,(9.21,-6.02,;10.05,-7.32,;11.59,-7.24,;12.43,-8.53,;13.97,-8.45,;14.66,-7.08,;13.82,-5.79,;12.29,-5.86,;16.2,-6.99,;17.03,-8.27,;18.56,-8.18,;19.26,-6.83,;18.41,-5.53,;16.88,-5.63,;7.68,-6.1,;6.84,-4.81,;5.31,-4.88,;4.6,-6.26,;5.44,-7.54,;6.98,-7.47,;3.06,-6.33,;2.22,-5.03,;.7,-5.11,;-.14,-3.81,;.56,-2.44,;2.1,-2.37,;2.94,-3.67,)| Show InChI InChI=1S/C22H31N5/c1-2-5-21(6-3-1)27-17-15-26(16-18-27)14-11-19-7-9-20(10-8-19)25-22-23-12-4-13-24-22/h1-6,12-13,19-20H,7-11,14-18H2,(H,23,24,25)/t19-,20-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063295 (CHEMBL165664 | [4-(4-Phenyl-piperazin-1-ylmethyl)-...) Show SMILES C([C@H]1CC[C@@H](CC1)Nc1ncccn1)N1CCN(CC1)c1ccccc1 |wU:4.7,wD:1.0,(7.44,-9.5,;6.6,-8.2,;7.3,-6.83,;6.46,-5.54,;4.91,-5.61,;4.22,-6.99,;5.06,-8.3,;4.07,-4.33,;4.76,-2.95,;3.91,-1.67,;4.61,-.29,;6.16,-.21,;7,-1.5,;6.3,-2.88,;8.98,-9.41,;9.69,-8.05,;11.21,-7.96,;12.06,-9.26,;11.37,-10.64,;9.83,-10.71,;13.6,-9.17,;14.43,-10.46,;15.96,-10.37,;16.66,-9.01,;15.81,-7.72,;14.28,-7.81,)| Show InChI InChI=1S/C21H29N5/c1-2-5-20(6-3-1)26-15-13-25(14-16-26)17-18-7-9-19(10-8-18)24-21-22-11-4-12-23-21/h1-6,11-12,18-19H,7-10,13-17H2,(H,22,23,24)/t18-,19-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair

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