Compile Data Set for Download or QSAR

Found 336 hits with Last Name = 'belliotti' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290221 (CHEMBL80919 | Thiophene-2-carboxylic acid (4-{2-[4...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccs3)CC2)c1Cl |wU:12.11,wD:15.18,(20.53,-4.53,;19.79,-5.88,;20.6,-7.19,;19.85,-8.55,;18.31,-8.59,;17.52,-7.26,;15.98,-7.29,;15.24,-8.63,;13.7,-8.66,;12.91,-7.36,;11.37,-7.38,;10.6,-8.73,;9.06,-8.73,;8.29,-10.06,;6.75,-10.06,;5.98,-8.73,;6.74,-7.4,;8.28,-7.4,;4.44,-8.75,;3.67,-10.08,;2.13,-10.09,;4.44,-11.41,;5.98,-11.49,;5.83,-14.15,;4.3,-14.05,;3.59,-12.7,;13.66,-6,;15.2,-5.98,;18.25,-5.91,;17.46,-4.6,)| Show InChI InChI=1S/C23H29Cl2N3OS/c24-19-3-1-4-20(22(19)25)28-14-12-27(13-15-28)11-10-17-6-8-18(9-7-17)26-23(29)21-5-2-16-30-21/h1-5,16-18H,6-15H2,(H,26,29)/t17-,18-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063292 (CHEMBL349426 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...) Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccccc12 |wU:17.22,wD:14.15,(10.31,-6.02,;11.15,-7.32,;12.69,-7.24,;13.39,-5.86,;14.93,-5.79,;15.76,-7.07,;15.07,-8.45,;13.53,-8.53,;17.3,-7,;17.99,-5.63,;19.5,-5.53,;20.36,-6.83,;19.66,-8.19,;18.13,-8.28,;8.79,-6.11,;7.95,-4.81,;6.42,-4.88,;5.72,-6.26,;6.55,-7.54,;8.09,-7.47,;4.18,-6.33,;3.34,-5.04,;4.04,-3.66,;3.23,-2.36,;1.69,-2.43,;.99,-3.81,;-.55,-3.87,;-1.26,-5.23,;-.44,-6.54,;1.1,-6.47,;1.8,-5.11,)| Show InChI InChI=1S/C26H33N5/c1-2-6-23(7-3-1)31-18-16-30(17-19-31)15-14-21-10-12-22(13-11-21)29-26-24-8-4-5-9-25(24)27-20-28-26/h1-9,20-22H,10-19H2,(H,27,28,29)/t21-,22-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cells				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...) Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [3H]- prazosin binding against Alpha-1A adrenergic receptor from rat submaxillary gland				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063279 (CHEMBL309623 | Cyclohexanecarboxylic acid {4-[2-(4...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)C1CCCCC1 |wU:6.6,wD:3.2,(1.34,-9.45,;2.88,-9.43,;3.66,-8.1,;5.2,-8.1,;5.97,-9.43,;7.51,-9.42,;8.29,-8.08,;9.83,-8.08,;10.6,-6.74,;12.14,-6.71,;12.89,-5.36,;14.44,-5.33,;15.22,-6.65,;14.48,-7.98,;12.94,-8.02,;16.77,-6.62,;17.56,-7.94,;19.09,-7.91,;19.85,-6.56,;19.04,-5.22,;17.5,-5.27,;7.51,-6.76,;5.96,-6.77,;3.66,-10.76,;5.19,-10.76,;5.95,-12.1,;5.18,-13.42,;3.66,-13.42,;2.88,-12.1,)| Show InChI InChI=1S/C25H39N3O/c29-25(22-7-3-1-4-8-22)26-23-13-11-21(12-14-23)15-16-27-17-19-28(20-18-27)24-9-5-2-6-10-24/h2,5-6,9-10,21-23H,1,3-4,7-8,11-20H2,(H,26,29)/t21-,23-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cells				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063279 (CHEMBL309623 | Cyclohexanecarboxylic acid {4-[2-(4...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)C1CCCCC1 |wU:6.6,wD:3.2,(1.34,-9.45,;2.88,-9.43,;3.66,-8.1,;5.2,-8.1,;5.97,-9.43,;7.51,-9.42,;8.29,-8.08,;9.83,-8.08,;10.6,-6.74,;12.14,-6.71,;12.89,-5.36,;14.44,-5.33,;15.22,-6.65,;14.48,-7.98,;12.94,-8.02,;16.77,-6.62,;17.56,-7.94,;19.09,-7.91,;19.85,-6.56,;19.04,-5.22,;17.5,-5.27,;7.51,-6.76,;5.96,-6.77,;3.66,-10.76,;5.19,-10.76,;5.95,-12.1,;5.18,-13.42,;3.66,-13.42,;2.88,-12.1,)| Show InChI InChI=1S/C25H39N3O/c29-25(22-7-3-1-4-8-22)26-23-13-11-21(12-14-23)15-16-27-17-19-28(20-18-27)24-9-5-2-6-10-24/h2,5-6,9-10,21-23H,1,3-4,7-8,11-20H2,(H,26,29)/t21-,23-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Rattus norvegicus (rat))	BDBM29568 (CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...) Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [3H]- prazosin binding against Alpha-1B adrenergic receptor from rat liver				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290206 (CHEMBL78800 | Thiophene-2-carboxylic acid (4-{2-[4...) Show SMILES Clc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1 |wU:13.13,wD:16.20,(14.4,-.17,;15.21,-1.48,;16.74,-1.45,;17.55,-2.76,;16.81,-4.11,;15.27,-4.15,;14.47,-2.83,;12.93,-2.85,;12.2,-4.2,;10.66,-4.23,;9.85,-2.92,;8.31,-2.95,;7.56,-4.29,;6.02,-4.3,;5.23,-5.63,;3.69,-5.63,;2.94,-4.3,;3.69,-2.97,;5.23,-2.97,;1.4,-4.32,;.63,-5.65,;-.91,-5.65,;1.4,-6.98,;2.92,-7.05,;2.78,-9.71,;1.24,-9.62,;.54,-8.27,;10.6,-1.57,;12.14,-1.55,)| Show InChI InChI=1S/C23H30ClN3OS/c24-20-4-1-2-5-21(20)27-15-13-26(14-16-27)12-11-18-7-9-19(10-8-18)25-23(28)22-6-3-17-29-22/h1-6,17-19H,7-16H2,(H,25,28)/t18-,19-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50063281 ((4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}...) Show SMILES COc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 |wU:17.21,wD:14.14,(16.78,-2.98,;16.09,-4.37,;16.94,-5.65,;18.47,-5.56,;19.33,-6.85,;18.62,-8.23,;17.09,-8.3,;16.26,-7.01,;14.71,-7.11,;14.02,-8.49,;12.47,-8.56,;11.63,-7.27,;10.08,-7.34,;9.24,-6.05,;7.71,-6.12,;6.86,-4.83,;5.33,-4.9,;4.62,-6.29,;5.46,-7.57,;7,-7.5,;3.07,-6.36,;2.23,-5.04,;2.95,-3.69,;2.11,-2.37,;.56,-2.44,;-.14,-3.83,;.7,-5.14,;12.33,-5.89,;13.87,-5.82,)| Show InChI InChI=1S/C23H33N5O/c1-29-22-6-3-2-5-21(22)28-17-15-27(16-18-28)14-11-19-7-9-20(10-8-19)26-23-24-12-4-13-25-23/h2-6,12-13,19-20H,7-11,14-18H2,1H3,(H,24,25,26)/t19-,20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290225 (CHEMBL78950 | Thiophene-2-carboxylic acid (4-{2-[4...) Show SMILES COc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1 |wU:14.14,wD:17.21,(16.01,-4.6,;17.55,-4.56,;18.35,-5.88,;19.89,-5.84,;20.69,-7.16,;19.95,-8.52,;18.41,-8.55,;17.61,-7.22,;16.07,-7.26,;15.34,-8.59,;13.8,-8.62,;13,-7.31,;11.46,-7.35,;10.69,-8.69,;9.15,-8.69,;8.38,-10.02,;6.84,-10.03,;6.07,-8.7,;6.84,-7.37,;8.38,-7.36,;4.53,-8.71,;3.76,-10.04,;2.22,-10.04,;4.53,-11.37,;6.07,-11.46,;5.93,-14.1,;4.39,-14.02,;3.69,-12.65,;13.75,-5.97,;15.29,-5.93,)| Show InChI InChI=1S/C24H33N3O2S/c1-29-22-6-3-2-5-21(22)27-16-14-26(15-17-27)13-12-19-8-10-20(11-9-19)25-24(28)23-7-4-18-30-23/h2-7,18-20H,8-17H2,1H3,(H,25,28)/t19-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50290221 (CHEMBL80919 | Thiophene-2-carboxylic acid (4-{2-[4...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccs3)CC2)c1Cl |wU:12.11,wD:15.18,(20.53,-4.53,;19.79,-5.88,;20.6,-7.19,;19.85,-8.55,;18.31,-8.59,;17.52,-7.26,;15.98,-7.29,;15.24,-8.63,;13.7,-8.66,;12.91,-7.36,;11.37,-7.38,;10.6,-8.73,;9.06,-8.73,;8.29,-10.06,;6.75,-10.06,;5.98,-8.73,;6.74,-7.4,;8.28,-7.4,;4.44,-8.75,;3.67,-10.08,;2.13,-10.09,;4.44,-11.41,;5.98,-11.49,;5.83,-14.15,;4.3,-14.05,;3.59,-12.7,;13.66,-6,;15.2,-5.98,;18.25,-5.91,;17.46,-4.6,)| Show InChI InChI=1S/C23H29Cl2N3OS/c24-19-3-1-4-20(22(19)25)28-14-12-27(13-15-28)11-10-17-6-8-18(9-7-17)26-23(29)21-5-2-16-30-21/h1-5,16-18H,6-15H2,(H,26,29)/t17-,18-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063291 (CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1cccs1 |wU:6.6,wD:3.2,(-4.1,-5.89,;-2.56,-5.89,;-1.79,-4.56,;-.25,-4.55,;.52,-5.88,;2.06,-5.86,;2.83,-4.53,;4.37,-4.53,;5.14,-3.2,;6.68,-3.16,;7.43,-1.82,;8.97,-1.78,;9.75,-3.1,;9.01,-4.44,;7.47,-4.46,;11.29,-3.06,;12.09,-4.39,;13.63,-4.36,;14.37,-3.01,;13.56,-1.69,;12.02,-1.73,;2.05,-3.2,;.51,-3.22,;-1.79,-7.22,;-.25,-7.3,;-.4,-9.95,;-1.93,-9.87,;-2.64,-8.5,)| Show InChI InChI=1S/C23H31N3OS/c27-23(22-7-4-18-28-22)24-20-10-8-19(9-11-20)12-13-25-14-16-26(17-15-25)21-5-2-1-3-6-21/h1-7,18-20H,8-17H2,(H,24,27)/t19-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063291 (CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1cccs1 |wU:6.6,wD:3.2,(-4.1,-5.89,;-2.56,-5.89,;-1.79,-4.56,;-.25,-4.55,;.52,-5.88,;2.06,-5.86,;2.83,-4.53,;4.37,-4.53,;5.14,-3.2,;6.68,-3.16,;7.43,-1.82,;8.97,-1.78,;9.75,-3.1,;9.01,-4.44,;7.47,-4.46,;11.29,-3.06,;12.09,-4.39,;13.63,-4.36,;14.37,-3.01,;13.56,-1.69,;12.02,-1.73,;2.05,-3.2,;.51,-3.22,;-1.79,-7.22,;-.25,-7.3,;-.4,-9.95,;-1.93,-9.87,;-2.64,-8.5,)| Show InChI InChI=1S/C23H31N3OS/c27-23(22-7-4-18-28-22)24-20-10-8-19(9-11-20)12-13-25-14-16-26(17-15-25)21-5-2-1-3-6-21/h1-7,18-20H,8-17H2,(H,24,27)/t19-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cells				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM85093 (CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM85093 (CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro binding affinity at human dopamine D4 receptor expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 8: 1499-502 (1999) BindingDB Entry DOI: 10.7270/Q2WH2P54
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50290206 (CHEMBL78800 | Thiophene-2-carboxylic acid (4-{2-[4...) Show SMILES Clc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1 |wU:13.13,wD:16.20,(14.4,-.17,;15.21,-1.48,;16.74,-1.45,;17.55,-2.76,;16.81,-4.11,;15.27,-4.15,;14.47,-2.83,;12.93,-2.85,;12.2,-4.2,;10.66,-4.23,;9.85,-2.92,;8.31,-2.95,;7.56,-4.29,;6.02,-4.3,;5.23,-5.63,;3.69,-5.63,;2.94,-4.3,;3.69,-2.97,;5.23,-2.97,;1.4,-4.32,;.63,-5.65,;-.91,-5.65,;1.4,-6.98,;2.92,-7.05,;2.78,-9.71,;1.24,-9.62,;.54,-8.27,;10.6,-1.57,;12.14,-1.55,)| Show InChI InChI=1S/C23H30ClN3OS/c24-20-4-1-2-5-21(20)27-15-13-26(14-16-27)12-11-18-7-9-19(10-8-18)25-23(28)22-6-3-17-29-22/h1-6,17-19H,7-16H2,(H,25,28)/t18-,19-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290214 (CHEMBL312430 | Furan-2-carboxylic acid (4-{2-[4-(2...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccco3)CC2)c1Cl |wU:12.11,wD:15.18,(20.54,-4.81,;19.81,-6.17,;20.61,-7.5,;19.86,-8.85,;18.32,-8.87,;17.53,-7.56,;15.99,-7.59,;15.27,-8.92,;13.73,-8.96,;12.93,-7.65,;11.39,-7.68,;10.62,-9.01,;9.08,-9.03,;8.31,-10.36,;6.77,-10.37,;6,-9.04,;6.75,-7.71,;8.29,-7.7,;4.46,-9.04,;3.69,-10.37,;2.15,-10.38,;4.46,-11.7,;5.96,-11.37,;6.74,-12.67,;5.72,-13.84,;4.3,-13.23,;13.67,-6.31,;15.21,-6.28,;18.28,-6.21,;17.48,-4.9,)| Show InChI InChI=1S/C23H29Cl2N3O2/c24-19-3-1-4-20(22(19)25)28-14-12-27(13-15-28)11-10-17-6-8-18(9-7-17)26-23(29)21-5-2-16-30-21/h1-5,16-18H,6-15H2,(H,26,29)/t17-,18-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290209 (CHEMBL310577 | Thiophene-2-carboxylic acid (4-{2-[...) Show SMILES COc1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1 |wU:14.14,wD:17.21,(17.13,-1.01,;17.93,-2.33,;17.18,-3.67,;18,-4.99,;17.25,-6.35,;15.71,-6.38,;14.92,-5.05,;15.66,-3.71,;13.38,-5.09,;12.65,-6.42,;11.11,-6.45,;10.3,-5.14,;8.76,-5.18,;8,-6.52,;6.46,-6.52,;5.68,-7.85,;4.14,-7.86,;3.38,-6.53,;4.14,-5.2,;5.68,-5.19,;1.84,-6.54,;1.07,-7.87,;-.47,-7.87,;1.84,-9.2,;3.37,-9.29,;3.23,-11.93,;1.69,-11.85,;.99,-10.48,;11.04,-3.8,;12.58,-3.76,)| Show InChI InChI=1S/C24H33N3O2S/c1-29-22-5-2-4-21(18-22)27-15-13-26(14-16-27)12-11-19-7-9-20(10-8-19)25-24(28)23-6-3-17-30-23/h2-6,17-20H,7-16H2,1H3,(H,25,28)/t19-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50290225 (CHEMBL78950 | Thiophene-2-carboxylic acid (4-{2-[4...) Show SMILES COc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1 |wU:14.14,wD:17.21,(16.01,-4.6,;17.55,-4.56,;18.35,-5.88,;19.89,-5.84,;20.69,-7.16,;19.95,-8.52,;18.41,-8.55,;17.61,-7.22,;16.07,-7.26,;15.34,-8.59,;13.8,-8.62,;13,-7.31,;11.46,-7.35,;10.69,-8.69,;9.15,-8.69,;8.38,-10.02,;6.84,-10.03,;6.07,-8.7,;6.84,-7.37,;8.38,-7.36,;4.53,-8.71,;3.76,-10.04,;2.22,-10.04,;4.53,-11.37,;6.07,-11.46,;5.93,-14.1,;4.39,-14.02,;3.69,-12.65,;13.75,-5.97,;15.29,-5.93,)| Show InChI InChI=1S/C24H33N3O2S/c1-29-22-6-3-2-5-21(22)27-16-14-26(15-17-27)13-12-19-8-10-20(11-9-19)25-24(28)23-7-4-18-30-23/h2-7,18-20H,8-17H2,1H3,(H,25,28)/t19-,20-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50290218 (CHEMBL78617 | Cyclopentanecarboxylic acid (4-{2-[4...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCCC3)CC2)c1Cl |wU:12.11,wD:15.18,(19.07,-5.05,;18.32,-6.4,;19.14,-7.71,;18.39,-9.08,;16.85,-9.11,;16.06,-7.78,;14.52,-7.82,;13.79,-9.15,;12.25,-9.18,;11.44,-7.87,;9.9,-7.91,;9.15,-9.25,;7.61,-9.25,;6.82,-10.58,;5.28,-10.59,;4.53,-9.26,;5.28,-7.93,;6.82,-7.92,;2.99,-9.27,;2.22,-10.6,;.68,-10.6,;2.94,-11.58,;1.7,-12.48,;2.17,-13.95,;3.71,-13.95,;4.18,-12.48,;12.19,-6.53,;13.73,-6.49,;16.8,-6.44,;15.99,-5.12,)| Show InChI InChI=1S/C24H35Cl2N3O/c25-21-6-3-7-22(23(21)26)29-16-14-28(15-17-29)13-12-18-8-10-20(11-9-18)27-24(30)19-4-1-2-5-19/h3,6-7,18-20H,1-2,4-5,8-17H2,(H,27,30)/t18-,20-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [3H]- pentazocine binding against alpha-1 from guinea pig brain				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290221 (CHEMBL80919 | Thiophene-2-carboxylic acid (4-{2-[4...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccs3)CC2)c1Cl |wU:12.11,wD:15.18,(20.53,-4.53,;19.79,-5.88,;20.6,-7.19,;19.85,-8.55,;18.31,-8.59,;17.52,-7.26,;15.98,-7.29,;15.24,-8.63,;13.7,-8.66,;12.91,-7.36,;11.37,-7.38,;10.6,-8.73,;9.06,-8.73,;8.29,-10.06,;6.75,-10.06,;5.98,-8.73,;6.74,-7.4,;8.28,-7.4,;4.44,-8.75,;3.67,-10.08,;2.13,-10.09,;4.44,-11.41,;5.98,-11.49,;5.83,-14.15,;4.3,-14.05,;3.59,-12.7,;13.66,-6,;15.2,-5.98,;18.25,-5.91,;17.46,-4.6,)| Show InChI InChI=1S/C23H29Cl2N3OS/c24-19-3-1-4-20(22(19)25)28-14-12-27(13-15-28)11-10-17-6-8-18(9-7-17)26-23(29)21-5-2-16-30-21/h1-5,16-18H,6-15H2,(H,26,29)/t17-,18-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083349 (6-[4-(3,4-Dimethyl-phenyl)-piperidin-1-ylmethyl]-4...) Show SMILES Cc1ccc(cc1C)C1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C22H26N2O2/c1-15-3-5-19(11-16(15)2)18-7-9-24(10-8-18)13-17-4-6-21-20(12-17)23-22(25)14-26-21/h3-6,11-12,18H,7-10,13-14H2,1-2H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50455438 (CHEMBL3084971) Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@H](CC1)Nc1ncccn1 |wU:17.22,14.15,(9.21,-6,;10.05,-7.3,;11.58,-7.21,;12.42,-8.52,;13.96,-8.42,;14.64,-7.05,;13.8,-5.77,;12.28,-5.84,;16.18,-6.98,;17.02,-8.26,;18.53,-8.17,;19.23,-6.81,;18.39,-5.51,;16.85,-5.6,;7.67,-6.09,;6.97,-7.44,;5.43,-7.51,;4.59,-6.23,;5.31,-4.86,;6.83,-4.79,;3.05,-6.3,;2.21,-5.02,;.7,-5.09,;-.14,-3.81,;.56,-2.43,;2.1,-2.36,;2.94,-3.64,)| Show InChI InChI=1S/C22H31N5/c1-2-5-21(6-3-1)27-17-15-26(16-18-27)14-11-19-7-9-20(10-8-19)25-22-23-12-4-13-24-22/h1-6,12-13,19-20H,7-11,14-18H2,(H,23,24,25)/t19-,20+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290210 (CHEMBL78368 | Thiophene-2-carboxylic acid (4-{2-[4...) Show SMILES Clc1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1 |wU:13.13,wD:16.20,(18.02,-2.32,;17.27,-3.67,;18.09,-5,;17.34,-6.35,;15.8,-6.38,;15.01,-5.06,;15.75,-3.72,;13.47,-5.09,;12.74,-6.42,;11.2,-6.46,;10.39,-5.16,;8.85,-5.19,;8.1,-6.52,;6.56,-6.53,;5.77,-7.86,;4.23,-7.87,;3.48,-6.54,;4.23,-5.21,;5.77,-5.2,;1.94,-6.54,;1.17,-7.87,;-.37,-7.89,;1.94,-9.2,;3.46,-9.29,;3.32,-11.95,;1.78,-11.86,;1.08,-10.5,;11.14,-3.81,;12.68,-3.78,)| Show InChI InChI=1S/C23H30ClN3OS/c24-19-3-1-4-21(17-19)27-14-12-26(13-15-27)11-10-18-6-8-20(9-7-18)25-23(28)22-5-2-16-29-22/h1-5,16-18,20H,6-15H2,(H,25,28)/t18-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063279 (CHEMBL309623 | Cyclohexanecarboxylic acid {4-[2-(4...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)C1CCCCC1 |wU:6.6,wD:3.2,(1.34,-9.45,;2.88,-9.43,;3.66,-8.1,;5.2,-8.1,;5.97,-9.43,;7.51,-9.42,;8.29,-8.08,;9.83,-8.08,;10.6,-6.74,;12.14,-6.71,;12.89,-5.36,;14.44,-5.33,;15.22,-6.65,;14.48,-7.98,;12.94,-8.02,;16.77,-6.62,;17.56,-7.94,;19.09,-7.91,;19.85,-6.56,;19.04,-5.22,;17.5,-5.27,;7.51,-6.76,;5.96,-6.77,;3.66,-10.76,;5.19,-10.76,;5.95,-12.1,;5.18,-13.42,;3.66,-13.42,;2.88,-12.1,)| Show InChI InChI=1S/C25H39N3O/c29-25(22-7-3-1-4-8-22)26-23-13-11-21(12-14-23)15-16-27-17-19-28(20-18-27)24-9-5-2-6-10-24/h2,5-6,9-10,21-23H,1,3-4,7-8,11-20H2,(H,26,29)/t21-,23-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (NEONATAL RAT)	BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [3H]- Yohimbine binding against rat kidney cortex Alpha-2B adrenergic receptor				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50063280 (CHEMBL355371 | {4-[2-(4-Pyridin-2-yl-piperazin-1-y...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,(9.19,-6.02,;10.03,-7.31,;11.57,-7.24,;12.41,-8.52,;13.95,-8.45,;14.64,-7.07,;13.8,-5.79,;12.27,-5.86,;16.18,-6.98,;17,-8.26,;18.54,-8.19,;19.23,-6.82,;18.38,-5.53,;16.86,-5.63,;7.67,-6.09,;6.83,-4.81,;5.3,-4.88,;4.59,-6.26,;5.43,-7.54,;6.97,-7.47,;3.05,-6.33,;2.21,-5.02,;.7,-5.11,;-.14,-3.81,;.56,-2.43,;2.1,-2.36,;2.94,-3.67,)| Show InChI InChI=1S/C21H30N6/c1-2-10-22-20(4-1)27-16-14-26(15-17-27)13-9-18-5-7-19(8-6-18)25-21-23-11-3-12-24-21/h1-4,10-12,18-19H,5-9,13-17H2,(H,23,24,25)/t18-,19-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290213 (CHEMBL80875 | Thiophene-2-carboxylic acid {4-[2-(4...) Show SMILES Cc1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1 |wU:13.13,wD:16.20,(17.72,-2.83,;16.97,-4.18,;17.79,-5.51,;17.04,-6.87,;15.5,-6.89,;14.71,-5.58,;15.45,-4.23,;13.17,-5.61,;12.44,-6.94,;10.9,-6.98,;10.09,-5.67,;8.55,-5.7,;7.79,-7.03,;6.25,-7.05,;5.47,-8.38,;3.93,-8.38,;3.17,-7.05,;3.93,-5.72,;5.47,-5.72,;1.63,-7.05,;.86,-8.38,;-.68,-8.4,;1.63,-9.71,;3.16,-9.81,;3.02,-12.46,;1.48,-12.37,;.78,-11.01,;10.83,-4.32,;12.37,-4.29,)| Show InChI InChI=1S/C24H33N3OS/c1-19-4-2-5-22(18-19)27-15-13-26(14-16-27)12-11-20-7-9-21(10-8-20)25-24(28)23-6-3-17-29-23/h2-6,17-18,20-21H,7-16H2,1H3,(H,25,28)/t20-,21-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290217 (CHEMBL78916 | N-{4-[2-(4-Phenyl-piperazin-1-yl)-et...) Show SMILES CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1 |wU:7.7,wD:4.3,(4.65,-12.02,;3.76,-10.79,;2.22,-10.79,;4.53,-9.46,;6.07,-9.45,;6.84,-10.78,;8.38,-10.76,;9.15,-9.43,;10.69,-9.43,;11.46,-8.1,;13,-8.06,;13.8,-9.36,;15.34,-9.34,;16.08,-8,;15.29,-6.68,;13.75,-6.72,;17.62,-7.96,;18.35,-6.63,;19.89,-6.59,;20.7,-7.91,;19.95,-9.26,;18.41,-9.29,;8.38,-8.1,;6.84,-8.12,)| Show InChI InChI=1S/C20H31N3O/c1-17(24)21-19-9-7-18(8-10-19)11-12-22-13-15-23(16-14-22)20-5-3-2-4-6-20/h2-6,18-19H,7-16H2,1H3,(H,21,24)/t18-,19-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083341 (7-(4-p-Tolyl-piperidin-1-ylmethyl)-4H-benzo[1,4]ox...) Show SMILES Cc1ccc(cc1)C1CCN(Cc2ccc3NC(=O)COc3c2)CC1 Show InChI InChI=1S/C21H24N2O2/c1-15-2-5-17(6-3-15)18-8-10-23(11-9-18)13-16-4-7-19-20(12-16)25-14-21(24)22-19/h2-7,12,18H,8-11,13-14H2,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083337 (7-[4-(3,4-Dimethyl-phenyl)-piperidin-1-ylmethyl]-4...) Show SMILES Cc1ccc(cc1C)C1CCN(Cc2ccc3NC(=O)COc3c2)CC1 Show InChI InChI=1S/C22H26N2O2/c1-15-3-5-19(11-16(15)2)18-7-9-24(10-8-18)13-17-4-6-20-21(12-17)26-14-22(25)23-20/h3-6,11-12,18H,7-10,13-14H2,1-2H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083350 (6-(4-p-Tolyl-piperidin-1-ylmethyl)-4H-benzo[1,4]ox...) Show SMILES Cc1ccc(cc1)C1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C21H24N2O2/c1-15-2-5-17(6-3-15)18-8-10-23(11-9-18)13-16-4-7-20-19(12-16)22-21(24)14-25-20/h2-7,12,18H,8-11,13-14H2,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50290214 (CHEMBL312430 | Furan-2-carboxylic acid (4-{2-[4-(2...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccco3)CC2)c1Cl |wU:12.11,wD:15.18,(20.54,-4.81,;19.81,-6.17,;20.61,-7.5,;19.86,-8.85,;18.32,-8.87,;17.53,-7.56,;15.99,-7.59,;15.27,-8.92,;13.73,-8.96,;12.93,-7.65,;11.39,-7.68,;10.62,-9.01,;9.08,-9.03,;8.31,-10.36,;6.77,-10.37,;6,-9.04,;6.75,-7.71,;8.29,-7.7,;4.46,-9.04,;3.69,-10.37,;2.15,-10.38,;4.46,-11.7,;5.96,-11.37,;6.74,-12.67,;5.72,-13.84,;4.3,-13.23,;13.67,-6.31,;15.21,-6.28,;18.28,-6.21,;17.48,-4.9,)| Show InChI InChI=1S/C23H29Cl2N3O2/c24-19-3-1-4-20(22(19)25)28-14-12-27(13-15-28)11-10-17-6-8-18(9-7-17)26-23(29)21-5-2-16-30-21/h1-5,16-18H,6-15H2,(H,26,29)/t17-,18-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063281 ((4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}...) Show SMILES COc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 |wU:17.21,wD:14.14,(16.78,-2.98,;16.09,-4.37,;16.94,-5.65,;18.47,-5.56,;19.33,-6.85,;18.62,-8.23,;17.09,-8.3,;16.26,-7.01,;14.71,-7.11,;14.02,-8.49,;12.47,-8.56,;11.63,-7.27,;10.08,-7.34,;9.24,-6.05,;7.71,-6.12,;6.86,-4.83,;5.33,-4.9,;4.62,-6.29,;5.46,-7.57,;7,-7.5,;3.07,-6.36,;2.23,-5.04,;2.95,-3.69,;2.11,-2.37,;.56,-2.44,;-.14,-3.83,;.7,-5.14,;12.33,-5.89,;13.87,-5.82,)| Show InChI InChI=1S/C23H33N5O/c1-29-22-6-3-2-5-21(22)28-17-15-27(16-18-28)14-11-19-7-9-20(10-8-19)26-23-24-12-4-13-25-23/h2-6,12-13,19-20H,7-11,14-18H2,1H3,(H,24,25,26)/t19-,20-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [3H]- MK-912 binding against human recombinant Alpha-2A adrenergic receptor				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290232 (CHEMBL309501 | Thiophene-2-carboxylic acid {4-[2-(...) Show SMILES Cc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1 |wU:13.13,wD:16.20,(14.33,-.78,;15.14,-2.08,;16.67,-2.05,;17.48,-3.37,;16.74,-4.72,;15.2,-4.76,;14.4,-3.44,;12.86,-3.46,;12.13,-4.81,;10.59,-4.84,;9.78,-3.53,;8.24,-3.55,;7.49,-4.9,;5.95,-4.91,;5.16,-6.24,;3.62,-6.24,;2.87,-4.91,;3.62,-3.58,;5.16,-3.58,;1.33,-4.92,;.56,-6.25,;-.98,-6.26,;1.33,-7.58,;2.85,-7.66,;2.71,-10.32,;1.17,-10.23,;.47,-8.87,;10.53,-2.18,;12.07,-2.15,)| Show InChI InChI=1S/C24H33N3OS/c1-19-5-2-3-6-22(19)27-16-14-26(15-17-27)13-12-20-8-10-21(11-9-20)25-24(28)23-7-4-18-29-23/h2-7,18,20-21H,8-17H2,1H3,(H,25,28)/t20-,21-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063292 (CHEMBL349426 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...) Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccccc12 |wU:17.22,wD:14.15,(10.31,-6.02,;11.15,-7.32,;12.69,-7.24,;13.39,-5.86,;14.93,-5.79,;15.76,-7.07,;15.07,-8.45,;13.53,-8.53,;17.3,-7,;17.99,-5.63,;19.5,-5.53,;20.36,-6.83,;19.66,-8.19,;18.13,-8.28,;8.79,-6.11,;7.95,-4.81,;6.42,-4.88,;5.72,-6.26,;6.55,-7.54,;8.09,-7.47,;4.18,-6.33,;3.34,-5.04,;4.04,-3.66,;3.23,-2.36,;1.69,-2.43,;.99,-3.81,;-.55,-3.87,;-1.26,-5.23,;-.44,-6.54,;1.1,-6.47,;1.8,-5.11,)| Show InChI InChI=1S/C26H33N5/c1-2-6-23(7-3-1)31-18-16-30(17-19-31)15-14-21-10-12-22(13-11-21)29-26-24-8-4-5-9-25(24)27-20-28-26/h1-9,20-22H,10-19H2,(H,27,28,29)/t21-,22-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063291 (CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1cccs1 |wU:6.6,wD:3.2,(-4.1,-5.89,;-2.56,-5.89,;-1.79,-4.56,;-.25,-4.55,;.52,-5.88,;2.06,-5.86,;2.83,-4.53,;4.37,-4.53,;5.14,-3.2,;6.68,-3.16,;7.43,-1.82,;8.97,-1.78,;9.75,-3.1,;9.01,-4.44,;7.47,-4.46,;11.29,-3.06,;12.09,-4.39,;13.63,-4.36,;14.37,-3.01,;13.56,-1.69,;12.02,-1.73,;2.05,-3.2,;.51,-3.22,;-1.79,-7.22,;-.25,-7.3,;-.4,-9.95,;-1.93,-9.87,;-2.64,-8.5,)| Show InChI InChI=1S/C23H31N3OS/c27-23(22-7-4-18-28-22)24-20-10-8-19(9-11-20)12-13-25-14-16-26(17-15-25)21-5-2-1-3-6-21/h1-7,18-20H,8-17H2,(H,24,27)/t19-,20-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063291 (CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1cccs1 |wU:6.6,wD:3.2,(-4.1,-5.89,;-2.56,-5.89,;-1.79,-4.56,;-.25,-4.55,;.52,-5.88,;2.06,-5.86,;2.83,-4.53,;4.37,-4.53,;5.14,-3.2,;6.68,-3.16,;7.43,-1.82,;8.97,-1.78,;9.75,-3.1,;9.01,-4.44,;7.47,-4.46,;11.29,-3.06,;12.09,-4.39,;13.63,-4.36,;14.37,-3.01,;13.56,-1.69,;12.02,-1.73,;2.05,-3.2,;.51,-3.22,;-1.79,-7.22,;-.25,-7.3,;-.4,-9.95,;-1.93,-9.87,;-2.64,-8.5,)| Show InChI InChI=1S/C23H31N3OS/c27-23(22-7-4-18-28-22)24-20-10-8-19(9-11-20)12-13-25-14-16-26(17-15-25)21-5-2-1-3-6-21/h1-7,18-20H,8-17H2,(H,24,27)/t19-,20-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50063296 (CHEMBL165679 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...) Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,(9.21,-6.02,;10.05,-7.32,;11.59,-7.24,;12.43,-8.53,;13.97,-8.45,;14.66,-7.08,;13.82,-5.79,;12.29,-5.86,;16.2,-6.99,;17.03,-8.27,;18.56,-8.18,;19.26,-6.83,;18.41,-5.53,;16.88,-5.63,;7.68,-6.1,;6.84,-4.81,;5.31,-4.88,;4.6,-6.26,;5.44,-7.54,;6.98,-7.47,;3.06,-6.33,;2.22,-5.03,;.7,-5.11,;-.14,-3.81,;.56,-2.44,;2.1,-2.37,;2.94,-3.67,)| Show InChI InChI=1S/C22H31N5/c1-2-5-21(6-3-1)27-17-15-26(16-18-27)14-11-19-7-9-20(10-8-19)25-22-23-12-4-13-24-22/h1-6,12-13,19-20H,7-11,14-18H2,(H,23,24,25)/t19-,20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063276 (CHEMBL164604 | {4-[2-(4-Phenyl-3,6-dihydro-2H-pyri...) Show SMILES C(CN1CCC(=CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,c:5,(9.23,-6.05,;10.08,-7.34,;11.62,-7.27,;12.47,-8.55,;14.01,-8.48,;14.71,-7.1,;13.86,-5.82,;12.33,-5.89,;16.25,-7.01,;17.08,-8.3,;18.62,-8.23,;19.32,-6.85,;18.46,-5.56,;16.93,-5.65,;7.7,-6.12,;6.86,-4.83,;5.32,-4.9,;4.61,-6.28,;5.46,-7.57,;7,-7.5,;3.07,-6.35,;2.22,-5.04,;.7,-5.14,;-.14,-3.82,;.56,-2.44,;2.11,-2.37,;2.95,-3.68,)| Show InChI InChI=1S/C23H30N4/c1-2-5-20(6-3-1)21-12-17-27(18-13-21)16-11-19-7-9-22(10-8-19)26-23-24-14-4-15-25-23/h1-6,12,14-15,19,22H,7-11,13,16-18H2,(H,24,25,26)/t19-,22-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cells				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083339 (6-[4-(4-Methoxy-phenyl)-piperidin-1-ylmethyl]-4H-b...) Show SMILES COc1ccc(cc1)C1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C21H24N2O3/c1-25-18-5-3-16(4-6-18)17-8-10-23(11-9-17)13-15-2-7-20-19(12-15)22-21(24)14-26-20/h2-7,12,17H,8-11,13-14H2,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50063276 (CHEMBL164604 | {4-[2-(4-Phenyl-3,6-dihydro-2H-pyri...) Show SMILES C(CN1CCC(=CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,c:5,(9.23,-6.05,;10.08,-7.34,;11.62,-7.27,;12.47,-8.55,;14.01,-8.48,;14.71,-7.1,;13.86,-5.82,;12.33,-5.89,;16.25,-7.01,;17.08,-8.3,;18.62,-8.23,;19.32,-6.85,;18.46,-5.56,;16.93,-5.65,;7.7,-6.12,;6.86,-4.83,;5.32,-4.9,;4.61,-6.28,;5.46,-7.57,;7,-7.5,;3.07,-6.35,;2.22,-5.04,;.7,-5.14,;-.14,-3.82,;.56,-2.44,;2.11,-2.37,;2.95,-3.68,)| Show InChI InChI=1S/C23H30N4/c1-2-5-20(6-3-1)21-12-17-27(18-13-21)16-11-19-7-9-22(10-8-19)26-23-24-14-4-15-25-23/h1-6,12,14-15,19,22H,7-11,13,16-18H2,(H,24,25,26)/t19-,22-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290218 (CHEMBL78617 | Cyclopentanecarboxylic acid (4-{2-[4...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCCC3)CC2)c1Cl |wU:12.11,wD:15.18,(19.07,-5.05,;18.32,-6.4,;19.14,-7.71,;18.39,-9.08,;16.85,-9.11,;16.06,-7.78,;14.52,-7.82,;13.79,-9.15,;12.25,-9.18,;11.44,-7.87,;9.9,-7.91,;9.15,-9.25,;7.61,-9.25,;6.82,-10.58,;5.28,-10.59,;4.53,-9.26,;5.28,-7.93,;6.82,-7.92,;2.99,-9.27,;2.22,-10.6,;.68,-10.6,;2.94,-11.58,;1.7,-12.48,;2.17,-13.95,;3.71,-13.95,;4.18,-12.48,;12.19,-6.53,;13.73,-6.49,;16.8,-6.44,;15.99,-5.12,)| Show InChI InChI=1S/C24H35Cl2N3O/c25-21-6-3-7-22(23(21)26)29-16-14-28(15-17-29)13-12-18-8-10-20(11-9-18)27-24(30)19-4-1-2-5-19/h3,6-7,18-20H,1-2,4-5,8-17H2,(H,27,30)/t18-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290212 (CHEMBL80315 | Thiophene-2-carboxylic acid (4-{2-[4...) Show SMILES CN([C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1)C(=O)c1cccs1 |wU:5.5,wD:2.1,(2.41,-5.51,;3.2,-6.86,;4.74,-6.84,;5.49,-8.17,;7.03,-8.17,;7.81,-6.84,;9.35,-6.83,;10.11,-5.49,;11.65,-5.47,;12.39,-4.11,;13.93,-4.09,;14.73,-5.4,;14,-6.74,;12.46,-6.77,;16.27,-5.37,;17.06,-6.69,;18.6,-6.66,;19.35,-5.3,;18.53,-3.99,;19.28,-2.64,;17,-4.02,;16.2,-2.71,;7.03,-5.51,;5.49,-5.51,;2.43,-8.17,;.89,-8.2,;3.2,-9.52,;4.72,-9.59,;4.58,-12.25,;3.04,-12.16,;2.34,-10.81,)| Show InChI InChI=1S/C24H31Cl2N3OS/c1-27(24(30)22-6-3-17-31-22)19-9-7-18(8-10-19)11-12-28-13-15-29(16-14-28)21-5-2-4-20(25)23(21)26/h2-6,17-19H,7-16H2,1H3/t18-,19-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083338 (6-(4-p-Tolyl-piperazin-1-ylmethyl)-4H-benzo[1,4]ox...) Show SMILES Cc1ccc(cc1)N1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C20H23N3O2/c1-15-2-5-17(6-3-15)23-10-8-22(9-11-23)13-16-4-7-19-18(12-16)21-20(24)14-25-19/h2-7,12H,8-11,13-14H2,1H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083342 (7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-be...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2ccc3NC(=O)COc3c2)CC1 Show InChI InChI=1S/C19H20ClN3O2/c20-15-2-4-16(5-3-15)23-9-7-22(8-10-23)12-14-1-6-17-18(11-14)25-13-19(24)21-17/h1-6,11H,7-10,12-13H2,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290211 (CHEMBL311575 | Thiophene-2-carboxylic acid {4-[2-(...) Show SMILES Cc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1 |wU:13.13,wD:16.20,(19.33,-5.48,;17.79,-5.51,;17.04,-6.87,;15.5,-6.89,;14.71,-5.58,;15.45,-4.23,;16.97,-4.18,;13.17,-5.61,;12.37,-4.29,;10.83,-4.32,;10.09,-5.67,;8.55,-5.7,;7.79,-7.03,;6.25,-7.05,;5.47,-8.38,;3.93,-8.38,;3.17,-7.05,;3.93,-5.72,;5.47,-5.72,;1.63,-7.05,;.86,-8.38,;-.68,-8.4,;1.63,-9.71,;3.16,-9.81,;3.02,-12.46,;1.48,-12.37,;.78,-11.01,;10.9,-6.98,;12.44,-6.94,)| Show InChI InChI=1S/C24H33N3OS/c1-19-4-10-22(11-5-19)27-16-14-26(15-17-27)13-12-20-6-8-21(9-7-20)25-24(28)23-3-2-18-29-23/h2-5,10-11,18,20-21H,6-9,12-17H2,1H3,(H,25,28)/t20-,21-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair

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