| Reaction Details |
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 | Report a problem with these data |
| Target | Envelope glycoprotein gp160 |
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| Ligand | BDBM50568665 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2106391 (CHEMBL4815066) |
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| IC50 | 2900±n/a nM |
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| Citation |  Kobayakawa, T; Tsuji, K; Konno, K; Himeno, A; Masuda, A; Yang, T; Takahashi, K; Ishida, Y; Ohashi, N; Kuwata, T; Matsumoto, K; Yoshimura, K; Sakawaki, H; Miura, T; Harada, S; Matsushita, S; Tamamura, H Hybrids of Small-Molecule CD4 Mimics with Polyethylene Glycol Units as HIV Entry Inhibitors. J Med Chem64:1481-1496 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Envelope glycoprotein gp160 |
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| Name: | Envelope glycoprotein gp160 |
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| Synonyms: | envelope glycoprotein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 91798.58 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | gi_45357394 |
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| Residue: | 814 |
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| Sequence: | MRVKGIRRNYQHLWRWGTMLLGMLMICSAKEQLWVTAYYGVPVWKEATTTLFCASDAKAY
DTEVHNVWATHACVPTDPNPREVVMGNVTEEFNIWNNSMVEQMHEDIISLWDESLKPCVK
LTPLCVTFNCTNYNGTRNGTTTEPPEVKNCTTKETGIKNCSFNIATSGVEDRFKKEYALL
YTADIVQIDNSSINYTLIGCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGK
GPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEVVIRSDNFSDNAKTIIVQLKDPVVINCT
RPNNNTRKGIRIGPGRTFYTTERIIGDIRQAHCNISRTQWNNTLRLIAAKLKKQFNNKTI
IFRNSSGGDPEIVMHSFNCGGEFFYCNTTQLFNSTWVHNNTWVHNNTGNDTEEGTITLPC
RIKQIINMWQEVGKAMYAPPIKGQIRCSSNITGLILTRDGGNTSSNNETFRPGGGDMRDN
WRSELYKYKVVKIEPLGVAPTKARRRVVQREKRAVGMLGAMFLGFLGAAGSTMGAASLAL
TVQARQVVSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLGDQQLLGIWG
CSGKLICTTAVPWNDSWSNKSLKYIWDNMTWMQWEKEIDIHVDTIYQLLEASQYQQEKNE
KDLLELDKWESLWNWFDITNWLWYIKIFIMIVGGLIGLRIVFTVLSIVNRVRQGYSPLSL
QTRLPTQRGPDRPEGIEEEGGERQRHIRSISEWILNNYPGRPAEPVPLQLPPLERLTLDC
NEDCGTSGTQGVGSPQVFVESPPVLESGTKEECC
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| BDBM50568665 |
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| n/a |
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| Name | BDBM50568665 |
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| Synonyms: | CHEMBL4875361 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H60ClN11O4 |
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| Mol. Mass. | 746.386 |
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| SMILES | NC(=N)NCCCCCCCC(=O)NCCCC[C@H](NC(N)=N)C(=O)NCCN1CCC(CC11CCCCC1)NC(=O)C(=O)Nc1ccc(Cl)cc1 |r| |
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| Structure | 
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