| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-induced degradation protein 4 homolog |
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| Ligand | BDBM50589804 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2194344 (CHEMBL5106704) |
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| IC50 | 4800±n/a nM |
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| Citation |  Chana, CK; Maisonneuve, P; Posternak, G; Grinberg, NGA; Poirson, J; Ona, SM; Ceccarelli, DF; Mader, P; St-Cyr, DJ; Pau, V; Kurinov, I; Tang, X; Deng, D; Cui, W; Su, W; Kuai, L; Soll, R; Tyers, M; Röst, HL; Batey, RA; Taipale, M; Gingras, AC; Sicheri, F Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4. J Med Chem65:12725-12746 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-induced degradation protein 4 homolog |
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| Name: | Glucose-induced degradation protein 4 homolog |
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| Synonyms: | C17orf39 | GID4 | GID4_HUMAN | VID24 | Vacuolar import and degradation protein 24 homolog |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33527.13 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_120713 |
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| Residue: | 300 |
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| Sequence: | MCARGQVGRGTQLRTGRPCSQVPGSRWRPERLLRRQRAGGRPSRPHPARARPGLSLPATL
LGSRAAAAVPLPLPPALAPGDPAMPVRTECPPPAGASAASAASLIPPPPINTQQPGVATS
LLYSGSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKGLTEEYPTLTTFFEGEII
SKKHPFLTRKWDADEDVDRKHWGKFLAFYQYAKSFNSDDFDYEELKNGDYVFMRWKEQFL
VPDHTIKDISGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNLTHVPEHSAPIYEFR
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| BDBM50589804 |
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| n/a |
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| Name | BDBM50589804 |
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| Synonyms: | CHEMBL5191076 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H36N4O3 |
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| Mol. Mass. | 512.6425 |
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| SMILES | CNC(=O)[C@H](Cc1ccc(C)cc1)NC(=O)[C@@H](C\C=C\c1ccccc1)NC(=O)CNCc1ccccc1 |r| |
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| Structure | 
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