| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50604767 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2249285 (CHEMBL5163495) |
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| EC50 | 9241±n/a nM |
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| Citation |  Xing, G; Li, D; Woo, AY; Zhi, Z; Ji, L; Xing, R; Lv, H; He, B; An, H; Zhao, H; Lin, B; Pan, L; Cheng, M Discovery of a Highly Selective ? J Med Chem65:5514-5527 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50604767 |
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| n/a |
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| Name | BDBM50604767 |
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| Synonyms: | CHEMBL5186459 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H21BrClN3O |
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| Mol. Mass. | 374.704 |
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| SMILES | Cl.Nc1c(Br)cc(cc1C#N)C(CO)NC1CCCCC1 |
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| Structure | 
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