| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50609011 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2275977 |
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| Ki | 1675±n/a nM |
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| Citation |  Chakraborty, S; Uprety, R; Slocum, ST; Irie, T; Le Rouzic, V; Li, X; Wilson, LL; Scouller, B; Alder, AF; Kruegel, AC; Ansonoff, M; Varadi, A; Eans, SO; Hunkele, A; Allaoa, A; Kalra, S; Xu, J; Pan, YX; Pintar, J; Kivell, BM; Pasternak, GW; Cameron, MD; McLaughlin, JP; Sames, D; Majumdar, S Oxidative Metabolism as a Modulator of Kratom's Biological Actions. J Med Chem64:16553-16572 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44431.62 |
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| Organism: | MOUSE |
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| Description: | OPIATE Mu OPRM1 MOUSE::P42866 |
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| Residue: | 398 |
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| Sequence: | MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50609011 |
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| n/a |
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| Name | BDBM50609011 |
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| Synonyms: | CHEMBL5287921 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H36N2O10 |
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| Mol. Mass. | 560.5928 |
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| SMILES | [H][C@@]12C[C@@H]([C@H](CC)CN1CCc1c2[nH]c2cccc(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)c12)C(=C/OC)\C(=O)OC |r| |
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| Structure | 
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