| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM50362701 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_797511 (CHEMBL1943341) |
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| EC50 | 6200±n/a nM |
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| Citation |  Houze, JB; Zhu, L; Sun, Y; Akerman, M; Qiu, W; Zhang, AJ; Sharma, R; Schmitt, M; Wang, Y; Liu, J; Liu, J; Medina, JC; Reagan, JD; Luo, J; Tonn, G; Zhang, J; Lu, JY; Chen, M; Lopez, E; Nguyen, K; Yang, L; Tang, L; Tian, H; Shuttleworth, SJ; Lin, DC AMG 837: a potent, orally bioavailable GPR40 agonist. Bioorg Med Chem Lett22:1267-70 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 31473.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14842 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
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| BDBM50362701 |
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| n/a |
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| Name | BDBM50362701 |
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| Synonyms: | CHEMBL1939647 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20O3 |
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| Mol. Mass. | 308.371 |
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| SMILES | CC#CC(CC(O)=O)c1ccc(OCCc2ccccc2)cc1 |
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| Structure | 
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