Compile Data Set for Download or QSAR

Found 114 hits with Last Name = 'lu' and Initial = 'jy'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pendrin (Mus musculus)	BDBM50512539 (CHEMBL4466170) Show SMILES Cn1nc(COc2cc(F)cc(F)c2)c2CN(CCc12)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C21H19ClF2N4O2/c1-27-20-6-7-28(21(29)25-16-4-2-13(22)3-5-16)11-18(20)19(26-27)12-30-17-9-14(23)8-15(24)10-17/h2-5,8-10H,6-7,11-12H2,1H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512543 (CHEMBL4546564) Show SMILES Cn1nc(COc2cc(F)cc(F)c2)c2CN(CCc12)C(=O)Nc1ccc(Br)cc1 Show InChI InChI=1S/C21H19BrF2N4O2/c1-27-20-6-7-28(21(29)25-16-4-2-13(22)3-5-16)11-18(20)19(26-27)12-30-17-9-14(23)8-15(24)10-17/h2-5,8-10H,6-7,11-12H2,1H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512535 (CHEMBL4435424) Show SMILES Cn1nc(COc2cc(F)c(F)c(F)c2)c2CN(CCc12)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C21H18ClF3N4O2/c1-28-19-6-7-29(21(30)26-13-4-2-12(22)3-5-13)10-15(19)18(27-28)11-31-14-8-16(23)20(25)17(24)9-14/h2-5,8-9H,6-7,10-11H2,1H3,(H,26,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512536 (CHEMBL4446784) Show SMILES Cn1nc(COc2ccc(F)c(F)c2)c2CN(CCc12)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C21H19ClF2N4O2/c1-27-20-8-9-28(21(29)25-14-4-2-13(22)3-5-14)11-16(20)19(26-27)12-30-15-6-7-17(23)18(24)10-15/h2-7,10H,8-9,11-12H2,1H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512537 (CHEMBL4474736) Show SMILES Cn1nc(COc2cccc(F)c2)c2CN(CCc12)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C21H20ClFN4O2/c1-26-20-9-10-27(21(28)24-16-7-5-14(22)6-8-16)12-18(20)19(25-26)13-29-17-4-2-3-15(23)11-17/h2-8,11H,9-10,12-13H2,1H3,(H,24,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Homo sapiens)	BDBM50512537 (CHEMBL4474736) Show SMILES Cn1nc(COc2cccc(F)c2)c2CN(CCc12)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C21H20ClFN4O2/c1-26-20-9-10-27(21(28)24-16-7-5-14(22)6-8-16)12-18(20)19(25-26)13-29-17-4-2-3-15(23)11-17/h2-8,11H,9-10,12-13H2,1H3,(H,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512533 (CHEMBL4575750) Show SMILES Cn1nc(COc2cc(F)cc(F)c2)c2CN(CCc12)C(=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C22H20F2N4O3/c1-27-20-7-8-28(22(30)25-21(29)14-5-3-2-4-6-14)12-18(20)19(26-27)13-31-17-10-15(23)9-16(24)11-17/h2-6,9-11H,7-8,12-13H2,1H3,(H,25,29,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512534 (CHEMBL4578218) Show SMILES Cn1nc(COc2cc(F)cc(F)c2)c2CN(CCc12)C(=O)NC1CCCCC1 Show InChI InChI=1S/C21H26F2N4O2/c1-26-20-7-8-27(21(28)24-16-5-3-2-4-6-16)12-18(20)19(25-26)13-29-17-10-14(22)9-15(23)11-17/h9-11,16H,2-8,12-13H2,1H3,(H,24,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512530 (CHEMBL4546431) Show SMILES Cn1nc(COc2cc(F)cc(F)c2)c2CN(CCc12)C(=S)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C21H19ClF2N4OS/c1-27-20-6-7-28(21(30)25-16-4-2-13(22)3-5-16)11-18(20)19(26-27)12-29-17-9-14(23)8-15(24)10-17/h2-5,8-10H,6-7,11-12H2,1H3,(H,25,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512529 (CHEMBL4436619) Show SMILES Cn1nc(COc2cc(F)cc(F)c2)c2CN(CCc12)S(=O)(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H18F5N3O3S/c1-28-20-6-7-29(33(30,31)17-4-2-13(3-5-17)21(24,25)26)11-18(20)19(27-28)12-32-16-9-14(22)8-15(23)10-16/h2-5,8-10H,6-7,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512531 (CHEMBL4577192) Show SMILES CN(C)c1ccc(NC(=S)N2CCc3c(C2)c(COc2cc(F)cc(F)c2)nn3C)cc1 Show InChI InChI=1S/C23H25F2N5OS/c1-28(2)18-6-4-17(5-7-18)26-23(32)30-9-8-22-20(13-30)21(27-29(22)3)14-31-19-11-15(24)10-16(25)12-19/h4-7,10-12H,8-9,13-14H2,1-3H3,(H,26,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512528 (CHEMBL4590521) Show SMILES Cn1nc(C(O)=O)c2CN(CCc12)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H15ClN4O3/c1-19-12-6-7-20(8-11(12)13(18-19)14(21)22)15(23)17-10-4-2-9(16)3-5-10/h2-5H,6-8H2,1H3,(H,17,23)(H,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512540 (CHEMBL4444793) Show SMILES CCN(CC)S(=O)(=O)N1CCc2c(C1)c(COc1cc(F)cc(F)c1)nn2C Show InChI InChI=1S/C18H24F2N4O3S/c1-4-23(5-2)28(25,26)24-7-6-18-16(11-24)17(21-22(18)3)12-27-15-9-13(19)8-14(20)10-15/h8-10H,4-7,11-12H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512541 (CHEMBL4571849) Show SMILES Cn1nc(COc2cc(F)cc(F)c2)c2CN(CCc12)C(=S)NC1CCCCC1 Show InChI InChI=1S/C21H26F2N4OS/c1-26-20-7-8-27(21(29)24-16-5-3-2-4-6-16)12-18(20)19(25-26)13-28-17-10-14(22)9-15(23)11-17/h9-11,16H,2-8,12-13H2,1H3,(H,24,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512542 (CHEMBL4445120) Show SMILES CCOC(=O)c1nn(C)c2CCN(Cc12)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C17H19ClN4O3/c1-3-25-16(23)15-13-10-22(9-8-14(13)21(2)20-15)17(24)19-12-6-4-11(18)5-7-12/h4-7H,3,8-10H2,1-2H3,(H,19,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512527 (CHEMBL4529094) Show SMILES Cn1nc(COc2cc(F)cc(F)c2)c2CN(CCc12)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H18ClF2N3O3S/c1-25-20-6-7-26(30(27,28)17-4-2-13(21)3-5-17)11-18(20)19(24-25)12-29-16-9-14(22)8-15(23)10-16/h2-5,8-10H,6-7,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512532 (CHEMBL4444063) Show SMILES Cn1nc(COc2cc(F)cc(F)c2)c2CN(CCc12)S(C)(=O)=O Show InChI InChI=1S/C15H17F2N3O3S/c1-19-15-3-4-20(24(2,21)22)8-13(15)14(18-19)9-23-12-6-10(16)5-11(17)7-12/h5-7H,3-4,8-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Pendrin (Mus musculus)	BDBM50512538 (CHEMBL4576357) Show SMILES CC(C)NC(=O)N1CCc2c(C1)c(COc1cc(F)cc(F)c1)nn2C Show InChI InChI=1S/C18H22F2N4O2/c1-11(2)21-18(25)24-5-4-17-15(9-24)16(22-23(17)3)10-26-14-7-12(19)6-13(20)8-14/h6-8,11H,4-5,9-10H2,1-3H3,(H,21,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...				Bioorg Med Chem Lett 29: 2119-2123 (2019) Article DOI: 10.1016/j.bmcl.2019.07.003 BindingDB Entry DOI: 10.7270/Q28D00M9
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299669 ((R)-1-phenyl-N-((4-phenyl-1H-imidazol-2-yl)methyl)...) Show SMILES C[C@@H](NCc1nc(cn1C)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C19H21N3/c1-15(16-9-5-3-6-10-16)20-13-19-21-18(14-22(19)2)17-11-7-4-8-12-17/h3-12,14-15,20H,13H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299670 ((R)-3-(2-chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl...) Show SMILES COc1cccc(c1)[C@@H](C)NCCCc1ccccc1Cl |r| Show InChI InChI=1S/C18H22ClNO/c1-14(16-8-5-10-17(13-16)21-2)20-12-6-9-15-7-3-4-11-18(15)19/h3-5,7-8,10-11,13-14,20H,6,9,12H2,1-2H3/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	194	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299671 ((R)-N-((1-methyl-4-phenyl-1H-imidazol-2-yl)methyl)...) Show SMILES C[C@@H](NCc1nc(c[nH]1)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C18H19N3/c1-14(15-8-4-2-5-9-15)19-13-18-20-12-17(21-18)16-10-6-3-7-11-16/h2-12,14,19H,13H2,1H3,(H,20,21)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299672 ((R)-1-phenyl-N-((2-phenyl-1,3-thiazol-5-yl)methyl)...) Show SMILES C[C@@H](NCc1cnc(s1)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C18H18N2S/c1-14(15-8-4-2-5-9-15)19-12-17-13-20-18(21-17)16-10-6-3-7-11-16/h2-11,13-14,19H,12H2,1H3/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299673 ((R)-1-phenyl-N-((4-phenyl-1,3-oxazol-2-yl)methyl)e...) Show SMILES C[C@@H](NCc1nc(co1)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C18H18N2O/c1-14(15-8-4-2-5-9-15)19-12-18-20-17(13-21-18)16-10-6-3-7-11-16/h2-11,13-14,19H,12H2,1H3/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299674 ((R)-1-phenyl-N-((4-phenyl-1,3-thiazol-2-yl)methyl)...) Show SMILES C[C@@H](NCc1nc(cs1)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C18H18N2S/c1-14(15-8-4-2-5-9-15)19-12-18-20-17(13-21-18)16-10-6-3-7-11-16/h2-11,13-14,19H,12H2,1H3/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299675 ((1R)-1-phenyl-N-((1-phenyl-1H-pyrazol-3-yl)methyl)...) Show SMILES C[C@@H](NCc1ccn(n1)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C18H19N3/c1-15(16-8-4-2-5-9-16)19-14-17-12-13-21(20-17)18-10-6-3-7-11-18/h2-13,15,19H,14H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299676 ((1R)-1-phenyl-N-((1R)-1-(1-(4-(trifluoromethyl)phe...) Show SMILES C[C@@H](N[C@H](C)c1ccccc1)c1ccn(n1)-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C20H20F3N3/c1-14(16-6-4-3-5-7-16)24-15(2)19-12-13-26(25-19)18-10-8-17(9-11-18)20(21,22)23/h3-15,24H,1-2H3/t14-,15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	233	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299677 ((1R)-N-((1R)-1-phenylethyl)-1-(1-(4-(trifluorometh...) Show SMILES CC[C@@H](N[C@H](C)c1ccccc1)c1ccn(n1)-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H22F3N3/c1-3-19(25-15(2)16-7-5-4-6-8-16)20-13-14-27(26-20)18-11-9-17(10-12-18)21(22,23)24/h4-15,19,25H,3H2,1-2H3/t15-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299678 ((1R)-2-methyl-N-((1R)-1-phenylethyl)-1-(1-(4-(trif...) Show SMILES CC(C)[C@@H](N[C@H](C)c1ccccc1)c1ccn(n1)-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C22H24F3N3/c1-15(2)21(26-16(3)17-7-5-4-6-8-17)20-13-14-28(27-20)19-11-9-18(10-12-19)22(23,24)25/h4-16,21,26H,1-3H3/t16-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299679 ((1R)-1-(3-fluorophenyl)-N-((1-(4-(trifluoromethyl)...) Show SMILES C[C@@H](N[C@H](C)c1cccc(F)c1)c1ccn(n1)-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C20H19F4N3/c1-13(15-4-3-5-17(21)12-15)25-14(2)19-10-11-27(26-19)18-8-6-16(7-9-18)20(22,23)24/h3-14,25H,1-2H3/t13-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	148	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299680 ((1R)-1-(3-chlorophenyl)-N-((1-(4-(trifluoromethyl)...) Show SMILES C[C@@H](N[C@H](C)c1cccc(Cl)c1)c1ccn(n1)-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C20H19ClF3N3/c1-13(15-4-3-5-17(21)12-15)25-14(2)19-10-11-27(26-19)18-8-6-16(7-9-18)20(22,23)24/h3-14,25H,1-2H3/t13-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	92	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299681 ((R)-N-((R)-1-(5-methoxy-1-(4-(trifluoromethyl)phen...) Show SMILES COc1cc(nn1-c1ccc(cc1)C(F)(F)F)[C@@H](C)N[C@H](C)c1ccccc1 |r| Show InChI InChI=1S/C21H22F3N3O/c1-14(16-7-5-4-6-8-16)25-15(2)19-13-20(28-3)27(26-19)18-11-9-17(10-12-18)21(22,23)24/h4-15,25H,1-3H3/t14-,15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299682 ((1R)-1-(3-chlorophenyl)-N-((1R)-1-(5-methoxy-1-(4-...) Show SMILES COc1cc(nn1-c1ccc(cc1)C(F)(F)F)[C@@H](C)N[C@H](C)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C21H21ClF3N3O/c1-13(15-5-4-6-17(22)11-15)26-14(2)19-12-20(29-3)28(27-19)18-9-7-16(8-10-18)21(23,24)25/h4-14,26H,1-3H3/t13-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	41	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299683 (1(R)-1-(1-(4-bromophenyl)-5-methoxy-1H-pyrazol-3-y...) Show SMILES COc1cc(nn1-c1ccc(Br)cc1)[C@@H](C)N[C@H](C)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H21BrClN3O/c1-13(15-5-4-6-17(22)11-15)23-14(2)19-12-20(26-3)25(24-19)18-9-7-16(21)8-10-18/h4-14,23H,1-3H3/t13-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299684 ((1R)-1-(3-chlorophenyl)-N-((1R)-1-(1-(3-chlorophen...) Show SMILES COc1cc(nn1-c1cccc(Cl)c1)[C@@H](C)N[C@H](C)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H21Cl2N3O/c1-13(15-6-4-7-16(21)10-15)23-14(2)19-12-20(26-3)25(24-19)18-9-5-8-17(22)11-18/h4-14,23H,1-3H3/t13-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299685 (4-(3-((R)-1-((R)-1-(3-chlorophenyl)ethylamino)ethy...) Show SMILES COc1cc(nn1-c1ccc(cc1)C(O)=O)[C@@H](C)N[C@H](C)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C21H22ClN3O3/c1-13(16-5-4-6-17(22)11-16)23-14(2)19-12-20(28-3)25(24-19)18-9-7-15(8-10-18)21(26)27/h4-14,23H,1-3H3,(H,26,27)/t13-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50299686 ((R)-1-(1-(4-(1H-tetrazol-5-yl)phenyl)-5-methoxy-1H...) Show SMILES COc1cc(nn1-c1ccc(cc1)-c1nnn[nH]1)[C@@H](C)N[C@H](C)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C21H22ClN7O/c1-13(16-5-4-6-17(22)11-16)23-14(2)19-12-20(30-3)29(26-19)18-9-7-15(8-10-18)21-24-27-28-25-21/h4-14,23H,1-3H3,(H,24,25,27,28)/t13-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay				J Med Chem 52: 6535-8 (2009) Article DOI: 10.1021/jm9012278 BindingDB Entry DOI: 10.7270/Q28052PS
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325724 ((R)-1-phenyl-N-((6-(trifluoromethoxy)-4'-(trifluor...) Show SMILES C[C@@H](NCc1ccc(OC(F)(F)F)c(c1)-c1ccc(cc1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C23H19F6NO/c1-15(17-5-3-2-4-6-17)30-14-16-7-12-21(31-23(27,28)29)20(13-16)18-8-10-19(11-9-18)22(24,25)26/h2-13,15,30H,14H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in absence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325725 ((R)-N-benzyl-1-(3-methoxyphenyl)ethanamine | CHEMB...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1ccccc1 |r| Show InChI InChI=1S/C16H19NO/c1-13(15-9-6-10-16(11-15)18-2)17-12-14-7-4-3-5-8-14/h3-11,13,17H,12H2,1-2H3/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325726 ((R)-N-(2-chlorobenzyl)-1-(3-methoxyphenyl)ethanami...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1ccccc1Cl |r| Show InChI InChI=1S/C16H18ClNO/c1-12(13-7-5-8-15(10-13)19-2)18-11-14-6-3-4-9-16(14)17/h3-10,12,18H,11H2,1-2H3/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325727 ((R)-N-((2'-chlorobiphenyl-3-yl)methyl)-1-(3-methox...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1cccc(c1)-c1ccccc1Cl |r| Show InChI InChI=1S/C22H22ClNO/c1-16(18-8-6-10-20(14-18)25-2)24-15-17-7-5-9-19(13-17)21-11-3-4-12-22(21)23/h3-14,16,24H,15H2,1-2H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325728 ((R)-N-(4-methoxybenzyl)-1-(3-methoxyphenyl)ethanam...) Show SMILES COc1ccc(CN[C@H](C)c2cccc(OC)c2)cc1 |r| Show InChI InChI=1S/C17H21NO2/c1-13(15-5-4-6-17(11-15)20-3)18-12-14-7-9-16(19-2)10-8-14/h4-11,13,18H,12H2,1-3H3/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325729 ((R)-N-((2'-fluorobiphenyl-3-yl)methyl)-1-(3-methox...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1cccc(c1)-c1ccccc1F |r| Show InChI InChI=1S/C22H22FNO/c1-16(18-8-6-10-20(14-18)25-2)24-15-17-7-5-9-19(13-17)21-11-3-4-12-22(21)23/h3-14,16,24H,15H2,1-2H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325730 ((R)-1-(3-methoxyphenyl)-N-((2'-methylbiphenyl-3-yl...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1cccc(c1)-c1ccccc1C |r| Show InChI InChI=1S/C23H25NO/c1-17-8-4-5-13-23(17)21-11-6-9-19(14-21)16-24-18(2)20-10-7-12-22(15-20)25-3/h4-15,18,24H,16H2,1-3H3/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325731 ((R)-N-((2'-methoxybiphenyl-3-yl)methyl)-1-(3-metho...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1cccc(c1)-c1ccccc1OC |r| Show InChI InChI=1S/C23H25NO2/c1-17(19-9-7-11-21(15-19)25-2)24-16-18-8-6-10-20(14-18)22-12-4-5-13-23(22)26-3/h4-15,17,24H,16H2,1-3H3/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325732 ((R)-N-((4'-methoxybiphenyl-3-yl)methyl)-1-(3-metho...) Show SMILES COc1ccc(cc1)-c1cccc(CN[C@H](C)c2cccc(OC)c2)c1 |r| Show InChI InChI=1S/C23H25NO2/c1-17(20-7-5-9-23(15-20)26-3)24-16-18-6-4-8-21(14-18)19-10-12-22(25-2)13-11-19/h4-15,17,24H,16H2,1-3H3/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	870	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325733 ((R)-1-(3-methoxyphenyl)-N-((4'-(trifluoromethyl)bi...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1cccc(c1)-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C23H22F3NO/c1-16(19-6-4-8-22(14-19)28-2)27-15-17-5-3-7-20(13-17)18-9-11-21(12-10-18)23(24,25)26/h3-14,16,27H,15H2,1-2H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325734 ((R)-N-((6-methoxy-4'-(trifluoromethyl)biphenyl-3-y...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1ccc(OC)c(c1)-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C24H24F3NO2/c1-16(19-5-4-6-21(14-19)29-2)28-15-17-7-12-23(30-3)22(13-17)18-8-10-20(11-9-18)24(25,26)27/h4-14,16,28H,15H2,1-3H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325735 ((R)-N-((6-methoxy-4'-(trifluoromethyl)biphenyl-3-y...) Show SMILES COc1ccc(CN[C@H](C)c2ccccc2)cc1-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C23H22F3NO/c1-16(18-6-4-3-5-7-18)27-15-17-8-13-22(28-2)21(14-17)19-9-11-20(12-10-19)23(24,25)26/h3-14,16,27H,15H2,1-2H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325736 ((R)-1-(3-fluorophenyl)-N-((6-methoxy-4'-(trifluoro...) Show SMILES COc1ccc(CN[C@H](C)c2cccc(F)c2)cc1-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C23H21F4NO/c1-15(18-4-3-5-20(24)13-18)28-14-16-6-11-22(29-2)21(12-16)17-7-9-19(10-8-17)23(25,26)27/h3-13,15,28H,14H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325737 (CHEMBL1224343 | N-((6-methoxy-4'-(trifluoromethyl)...) Show SMILES COc1ccc(CNC(C)c2cccc(C)c2)cc1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H24F3NO/c1-16-5-4-6-20(13-16)17(2)28-15-18-7-12-23(29-3)22(14-18)19-8-10-21(11-9-19)24(25,26)27/h4-14,17,28H,15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair

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